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BOLD-based cerebrovascular reactivity vascular transfer function isolates amplitude and timing responses to better characterize cerebral small vessel disease.

Atwi S, Shao H, Crane DE, da Costa L, Aviv RI, Mikulis DJ, Black SE, MacIntosh BJ.

NMR Biomed. 2019 Jan 29:e4064. doi: 10.1002/nbm.4064. [Epub ahead of print]


Response by Vagal et al to Letter Regarding Article, "Collateral Clock Is More Important Than Time Clock for Tissue Fate: A Natural History Study of Acute Ischemic Strokes".

Vagal A, Aviv R, Wintermark M.

Stroke. 2018 Dec;49(12):e340. doi: 10.1161/STROKEAHA.118.023440. No abstract available.


Collateral Clock Is More Important Than Time Clock for Tissue Fate.

Vagal A, Aviv R, Sucharew H, Reddy M, Hou Q, Michel P, Jovin T, Tomsick T, Wintermark M, Khatri P.

Stroke. 2018 Sep;49(9):2102-2107. doi: 10.1161/STROKEAHA.118.021484.


Cost-effectiveness of targeted thrombolytic therapy for stroke patients using multi-modal CT compared to usual practice.

Reeves P, Edmunds K, Levi C, Lin L, Cheng X, Aviv R, Kleinig T, Butcher K, Zhang J, Parsons M, Bivard A.

PLoS One. 2018 Oct 23;13(10):e0206203. doi: 10.1371/journal.pone.0206203. eCollection 2018.


Prospective Multicenter Study of Changes in MTT after Aneurysmal SAH and Relationship to Delayed Cerebral Ischemia in Patients with Good- and Poor-Grade Admission Status.

Murphy A, Lee TY, Marotta TR, Spears J, Macdonald RL, Aviv RI, Baker A, Bharatha A.

AJNR Am J Neuroradiol. 2018 Nov;39(11):2027-2033. doi: 10.3174/ajnr.A5844. Epub 2018 Oct 18.


Single-phase CT angiography: collateral grade is independent of scan weighting.

Bisson DA, Mahmoudian D, Shatil AS, Waggass G, Zhang L, Levi C, Spratt NJ, Lin L, Liebeskind D, Parsons M, Bivard A, Aviv RI.

Neuroradiology. 2019 Jan;61(1):19-28. doi: 10.1007/s00234-018-2105-2. Epub 2018 Oct 4.


Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data.

Al-Shahi Salman R, Frantzias J, Lee RJ, Lyden PD, Battey TWK, Ayres AM, Goldstein JN, Mayer SA, Steiner T, Wang X, Arima H, Hasegawa H, Oishi M, Godoy DA, Masotti L, Dowlatshahi D, Rodriguez-Luna D, Molina CA, Jang DK, Davalos A, Castillo J, Yao X, Claassen J, Volbers B, Kazui S, Okada Y, Fujimoto S, Toyoda K, Li Q, Khoury J, Delgado P, Sabín JÁ, Hernández-Guillamon M, Prats-Sánchez L, Cai C, Kate MP, McCourt R, Venkatasubramanian C, Diringer MN, Ikeda Y, Worthmann H, Ziai WC, d'Esterre CD, Aviv RI, Raab P, Murai Y, Zazulia AR, Butcher KS, Seyedsaadat SM, Grotta JC, Martí-Fàbregas J, Montaner J, Broderick J, Yamamoto H, Staykov D, Connolly ES, Selim M, Leira R, Moon BH, Demchuk AM, Di Napoli M, Fujii Y, Anderson CS, Rosand J; VISTA-ICH Collaboration; ICH Growth Individual Patient Data Meta-analysis Collaborators.

Lancet Neurol. 2018 Oct;17(10):885-894. doi: 10.1016/S1474-4422(18)30253-9. Epub 2018 Aug 14. Erratum in: Lancet Neurol. 2018 Sep 19;:.


Intravenous Thrombolysis May Not Improve Clinical Outcome of Acute Ischemic Stroke Patients Without a Baseline Vessel Occlusion.

Tian H, Parsons MW, Levi CR, Cheng X, Aviv RI, Spratt NJ, Kleinig TJ, O'Brien B, Butcher KS, Lin L, Zhang J, Dong Q, Chen C, Bivard A.

Front Neurol. 2018 Jun 6;9:405. doi: 10.3389/fneur.2018.00405. eCollection 2018.


Carotid near-occlusion can be identified with ultrasound by low flow velocity distal to the stenosis.

Johansson E, Benhabib H, Herod W, Hopyan J, Machnowska M, Maggisano R, Aviv R, Fox AJ.

Acta Radiol. 2019 Mar;60(3):396-404. doi: 10.1177/0284185118780900. Epub 2018 Jun 13.


Combining Spot Sign and Intracerebral Hemorrhage Score to Estimate Functional Outcome: Analysis From the PREDICT Cohort.

Schneider H, Huynh TJ, Demchuk AM, Dowlatshahi D, Rodriguez-Luna D, Silva Y, Aviv R, Dzialowski I; PREDICT/Sunnybrook ICH CTA Study Group.

Stroke. 2018 Jun;49(6):1511-1514. doi: 10.1161/STROKEAHA.118.020679. Epub 2018 May 2.


Predicting Intracerebral Hemorrhage Expansion With Noncontrast Computed Tomography: The BAT Score.

Morotti A, Dowlatshahi D, Boulouis G, Al-Ajlan F, Demchuk AM, Aviv RI, Yu L, Schwab K, Romero JM, Gurol ME, Viswanathan A, Anderson CD, Chang Y, Greenberg SM, Qureshi AI, Rosand J, Goldstein JN; ATACH-II, NETT, and PREDICT Investigators.

Stroke. 2018 May;49(5):1163-1169. doi: 10.1161/STROKEAHA.117.020138. Epub 2018 Apr 18. Erratum in: Stroke. 2018 Sep;49(9):e297.


Rationale and evidence for the development of a durable device-based cardiac neuromodulation therapy for hypertension.

Yang B, Wang Y, Zhang F, Ju W, Chen H, Mika Y, Aviv R, Evans SJ, Burkhoff D, Wang J, Chen M.

J Am Soc Hypertens. 2018 May;12(5):381-391. doi: 10.1016/j.jash.2018.03.004. Epub 2018 Mar 21.


Lack of Early Improvement Predicts Poor Outcome Following Acute Intracerebral Hemorrhage.

Yogendrakumar V, Smith EE, Demchuk AM, Aviv RI, Rodriguez-Luna D, Molina CA, Silva Blas Y, Dzialowski I, Kobayashi A, Boulanger JM, Lum C, Gubitz G, Padma V, Roy J, Kase CS, Bhatia R, Ali M, Lyden P, Hill MD, Dowlatshahi D; Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign [PREDICT]/Sunnybrook ICH CTA Study Group and the Virtual International Stroke Trials Archive (VISTA)-ICH Collaborators.

Crit Care Med. 2018 Apr;46(4):e310-e317. doi: 10.1097/CCM.0000000000002962.


Carotid near-occlusion frequently has high peak systolic velocity on Doppler ultrasound.

Khangure SR, Benhabib H, Machnowska M, Fox AJ, Grönlund C, Herod W, Maggisano R, Sjöberg A, Wester P, Hojjat SP, Hopyan J, Aviv RI, Johansson E.

Neuroradiology. 2018 Jan;60(1):17-25. doi: 10.1007/s00234-017-1938-4. Epub 2017 Nov 25.


Do Intracerebral Hemorrhage Nonexpanders Actually Expand Into the Ventricular Space?

Dowlatshahi D, Deshpande A, Aviv RI, Rodriguez-Luna D, Molina CA, Blas YS, Dzialowski I, Kobayashi A, Boulanger JM, Lum C, Gubitz GJ, Padma V, Roy J, Kase CS, Bhatia R, Hill MD, Demchuk AM; PREDICT ICH CTA Study Group.

Stroke. 2018 Jan;49(1):201-203. doi: 10.1161/STROKEAHA.117.018716. Epub 2017 Nov 22.


Spatial Correlation of Pathology and Perfusion Changes within the Cortex and White Matter in Multiple Sclerosis.

Mulholland AD, Vitorino R, Hojjat SP, Ma AY, Zhang L, Lee L, Carroll TJ, Cantrell CG, Figley CR, Aviv RI.

AJNR Am J Neuroradiol. 2018 Jan;39(1):91-96. doi: 10.3174/ajnr.A5410. Epub 2017 Nov 2.


An Algorithm for Managing Intraosseous Vascular Anomalies of the Craniofacial Skeleton.

Isaac KV, Teshima TL, Aviv RI, Fazl M, da Costa L, Mainprize T, Antonyshyn O.

J Craniofac Surg. 2018 May;29(3):622-627. doi: 10.1097/SCS.0000000000004014.


Normal appearing white matter permeability: a marker of inflammation and information processing speed deficit among relapsing remitting multiple sclerosis patients.

Eftekhari E, Hojjat SP, Vitorino R, Carroll TJ, Cantrell CG, Lee L, Taylor MW, Morrow SA, Benhabib H, Aviv RI, Kassner A.

Neuroradiology. 2017 Aug;59(8):771-780. doi: 10.1007/s00234-017-1862-7. Epub 2017 Jun 16.


CT-based Techniques for Brain Perfusion.

Krishnan P, Murphy A, Aviv RI.

Top Magn Reson Imaging. 2017 Jun;26(3):113-119. doi: 10.1097/RMR.0000000000000129. Review.


Use of Noncontrast Computed Tomography and Computed Tomographic Perfusion in Predicting Intracerebral Hemorrhage After Intravenous Alteplase Therapy.

Batchelor C, Pordeli P, d'Esterre CD, Najm M, Al-Ajlan FS, Boesen ME, McDougall C, Hur L, Fainardi E, Shankar JJS, Rubiera M, Khaw AV, Hill MD, Demchuk AM, Sajobi TT, Goyal M, Lee TY, Aviv RI, Menon BK.

Stroke. 2017 Jun;48(6):1548-1553. doi: 10.1161/STROKEAHA.117.016616. Epub 2017 Apr 26.


Imaging biomarkers in Parkinson's disease and Parkinsonian syndromes: current and emerging concepts.

Saeed U, Compagnone J, Aviv RI, Strafella AP, Black SE, Lang AE, Masellis M.

Transl Neurodegener. 2017 Mar 28;6:8. doi: 10.1186/s40035-017-0076-6. eCollection 2017. Review.


Changes in Cerebral Perfusion with Induced Hypertension in Aneurysmal Subarachnoid Hemorrhage: A Pilot and Feasibility Study.

Murphy A, de Oliveira Manoel AL, Macdonald RL, Baker A, Lee TY, Marotta T, Montanera W, Aviv R, Bharatha A.

Neurocrit Care. 2017 Aug;27(1):3-10. doi: 10.1007/s12028-017-0379-6.


Critical Illness-Associated Cerebral Microbleeds.

Fanou EM, Coutinho JM, Shannon P, Kiehl TR, Levi MM, Wilcox ME, Aviv RI, Mandell DM.

Stroke. 2017 Apr;48(4):1085-1087. doi: 10.1161/STROKEAHA.116.016289. Epub 2017 Feb 24.


The relationship between white matter fiber damage and gray matter perfusion in large-scale functionally defined networks in multiple sclerosis.

Ma AY, Vitorino RC, Hojjat SP, Mulholland AD, Zhang L, Lee L, Carroll TJ, Cantrell CG, Figley CR, Aviv RI.

Mult Scler. 2017 Dec;23(14):1884-1892. doi: 10.1177/1352458517691149. Epub 2017 Feb 9.


Validating a Predictive Model of Acute Advanced Imaging Biomarkers in Ischemic Stroke.

Bivard A, Levi C, Lin L, Cheng X, Aviv R, Spratt NJ, Lou M, Kleinig T, O'Brien B, Butcher K, Zhang J, Jannes J, Dong Q, Parsons M.

Stroke. 2017 Mar;48(3):645-650. doi: 10.1161/STROKEAHA.116.015143. Epub 2017 Jan 19.


Perfusion computed tomography in patients with stroke thrombolysis.

Kawano H, Bivard A, Lin L, Ma H, Cheng X, Aviv R, O'Brien B, Butcher K, Lou M, Zhang J, Jannes J, Dong Q, Levi CR, Parsons MW.

Brain. 2017 Mar 1;140(3):684-691. doi: 10.1093/brain/aww338.


Comparison of Time-Resolved and First-Pass Contrast-Enhanced MR Angiography in Pretherapeutic Evaluation of Spinal Dural Arteriovenous Fistulas.

Mathur S, Bharatha A, Huynh TJ, Aviv RI, Symons SP.

AJNR Am J Neuroradiol. 2017 Jan;38(1):206-212. doi: 10.3174/ajnr.A4962. Epub 2016 Nov 3.


First-Pass Contrast-Enhanced MR Angiography in Evaluation of Treated Spinal Arteriovenous Fistulas: Is Catheter Angiography Necessary?

Mathur S, Symons SP, Huynh TJ, Marotta TR, Aviv RI, Bharatha A.

AJNR Am J Neuroradiol. 2017 Jan;38(1):200-205. doi: 10.3174/ajnr.A4971. Epub 2016 Nov 3.


Zinc deficiency presenting as diarrhea and diffuse erythroderma.

Aviv R, Toh J, Eisenberg R, Khanna S, Jariwala SP.

Ann Allergy Asthma Immunol. 2016 Dec;117(6):707-708. doi: 10.1016/j.anai.2016.09.002. Epub 2016 Oct 19. No abstract available.


Comparison of Quantitative Cerebral Blood Flow Measurements Performed by Bookend Dynamic Susceptibility Contrast and Arterial Spin-Labeling MRI in Relapsing-Remitting Multiple Sclerosis.

D'Ortenzio RM, Hojjat SP, Vitorino R, Cantrell CG, Lee L, Feinstein A, O'Connor P, Carroll TJ, Aviv RI.

AJNR Am J Neuroradiol. 2016 Dec;37(12):2265-2272. Epub 2016 Sep 29.


Too good to treat? ischemic stroke patients with small computed tomography perfusion lesions may not benefit from thrombolysis.

Bivard A, Lou M, Levi CR, Krishnamurthy V, Cheng X, Aviv RI, McElduff P, Lin L, Kleinig T, O'Brien B, Butcher K, Jingfen Z, Jannes J, Dong Q, Parsons MW.

Ann Neurol. 2016 Aug;80(2):286-93. doi: 10.1002/ana.24714. Epub 2016 Jul 26.


Ultraearly hematoma growth in active intracerebral hemorrhage.

Rodriguez-Luna D, Coscojuela P, Rubiera M, Hill MD, Dowlatshahi D, Aviv RI, Silva Y, Dzialowski I, Lum C, Czlonkowska A, Boulanger JM, Kase CS, Gubitz G, Bhatia R, Padma V, Roy J, Tomasello A, Demchuk AM, Molina CA; PREDICT/Sunnybrook ICH CTA Study Group.

Neurology. 2016 Jul 26;87(4):357-64. doi: 10.1212/WNL.0000000000002897. Epub 2016 Jun 24.


Diagnostic Performance of Routine Brain MRI Sequences for Dural Venous Sinus Thrombosis.

Patel D, Machnowska M, Symons S, Yeung R, Fox AJ, Aviv RI, Jabehdar Maralani P.

AJNR Am J Neuroradiol. 2016 Nov;37(11):2026-2032. doi: 10.3174/ajnr.A4843. Epub 2016 Jun 16.


Remote Cerebellar Stroke Associated With Delusions and Disorganization.

Neufeld N, Gallagher D, Aviv R, Feinstein A.

J Neuropsychiatry Clin Neurosci. 2016 Jun 3:appineuropsych15110398. [Epub ahead of print] No abstract available.


Regional Frontal Perfusion Deficits in Relapsing-Remitting Multiple Sclerosis with Cognitive Decline.

Vitorino R, Hojjat SP, Cantrell CG, Feinstein A, Zhang L, Lee L, O'Connor P, Carroll TJ, Aviv RI.

AJNR Am J Neuroradiol. 2016 Oct;37(10):1800-1807. doi: 10.3174/ajnr.A4824. Epub 2016 May 19.


Cortical Perfusion Alteration in Normal-Appearing Gray Matter Is Most Sensitive to Disease Progression in Relapsing-Remitting Multiple Sclerosis.

Hojjat SP, Kincal M, Vitorino R, Cantrell CG, Feinstein A, Zhang L, Lee L, O'Connor P, Carroll TJ, Aviv RI.

AJNR Am J Neuroradiol. 2016 Aug;37(8):1454-61. doi: 10.3174/ajnr.A4737. Epub 2016 Mar 24.


Diffusion Tensor Imaging Tractography of the Facial Nerve in Patients With Cerebellopontine Angle Tumors.

Hilly O, Chen JM, Birch J, Hwang E, Lin VY, Aviv RI, Symons SP.

Otol Neurotol. 2016 Apr;37(4):388-93. doi: 10.1097/MAO.0000000000000984.


Magnitude of Hematoma Volume Measurement Error in Intracerebral Hemorrhage.

Rodriguez-Luna D, Boyko M, Subramaniam S, Klourfeld E, Jo P, Diederichs BJ, Kosior JC, Dowlatshahi D, Aviv RI, Molina CA, Hill MD, Demchuk AM; PREDICT/Sunnybrook ICH CTA study group.

Stroke. 2016 Apr;47(4):1124-6. doi: 10.1161/STROKEAHA.115.012170. Epub 2016 Feb 18.


Perfusion reduction in the absence of structural differences in cognitively impaired versus unimpaired RRMS patients.

Hojjat SP, Cantrell CG, Carroll TJ, Vitorino R, Feinstein A, Zhang L, Symons SP, Morrow SA, Lee L, O'Connor P, Aviv RI.

Mult Scler. 2016 Nov;22(13):1685-1694. Epub 2016 Feb 4.


Predicting Intracerebral Hemorrhage Growth With the Spot Sign: The Effect of Onset-to-Scan Time.

Dowlatshahi D, Brouwers HB, Demchuk AM, Hill MD, Aviv RI, Ufholz LA, Reaume M, Wintermark M, Hemphill JC 3rd, Murai Y, Wang Y, Zhao X, Wang Y, Li N, Sorimachi T, Matsumae M, Steiner T, Rizos T, Greenberg SM, Romero JM, Rosand J, Goldstein JN, Sharma M.

Stroke. 2016 Mar;47(3):695-700. doi: 10.1161/STROKEAHA.115.012012. Epub 2016 Feb 4. Review.


The predictive capacity of apparent diffusion coefficient (ADC) in response assessment of brain metastases following radiation.

Jakubovic R, Zhou S, Heyn C, Soliman H, Zhang L, Aviv R, Sahgal A.

Clin Exp Metastasis. 2016 Mar;33(3):277-84. doi: 10.1007/s10585-016-9778-x. Epub 2016 Jan 19.


Small intracerebral hemorrhages have a low spot sign prevalence and are less likely to expand.

Dowlatshahi D, Yogendrakumar V, Aviv RI, Rodriguez-Luna D, Molina CA, Silva Y, Dzialowski I, Czlonkowska A, Boulanger JM, Lum C, Gubitz G, Padma V, Roy J, Kase CS, Bhatia R, Hill MD, Demchuk AM; PREDICT/Sunnybrook ICH CTA study group.

Int J Stroke. 2016 Feb;11(2):191-7. doi: 10.1177/1747493015616635.


Regional reduction in cortical blood flow among cognitively impaired adults with relapsing-remitting multiple sclerosis patients.

Hojjat SP, Cantrell CG, Vitorino R, Feinstein A, Shirzadi Z, MacIntosh BJ, Crane DE, Zhang L, Morrow SA, Lee L, O'Connor P, Carroll TJ, Aviv RI.

Mult Scler. 2016 Oct;22(11):1421-1428. Epub 2016 Jan 11.


Perihematomal Edema Is Greater in the Presence of a Spot Sign but Does Not Predict Intracerebral Hematoma Expansion.

Rodriguez-Luna D, Stewart T, Dowlatshahi D, Kosior JC, Aviv RI, Molina CA, Silva Y, Dzialowski I, Lum C, Czlonkowska A, Boulanger JM, Kase CS, Gubitz G, Bhatia R, Padma V, Roy J, Subramaniam S, Hill MD, Demchuk AM; PREDICT/Sunnybrook ICH CTA Study Group.

Stroke. 2016 Feb;47(2):350-5. doi: 10.1161/STROKEAHA.115.011295. Epub 2015 Dec 22.


Multiphase CT Angiography: A Poor Man's Perfusion CT?

Aviv RI, Parsons M, Bivard A, Jahromi B, Wintermark M.

Radiology. 2015 Dec;277(3):922-4. doi: 10.1148/radiol.2015150820. No abstract available.


Emergency Imaging of Intracerebral Haemorrhage.

Alobeidi F, Aviv RI.

Front Neurol Neurosci. 2015;37:13-26. doi: 10.1159/000437110. Epub 2015 Nov 12. Review.


Effect of Collaterals on Clinical Presentation, Baseline Imaging, Complications, and Outcome in Acute Stroke.

Fanou EM, Knight J, Aviv RI, Hojjat SP, Symons SP, Zhang L, Wintermark M.

AJNR Am J Neuroradiol. 2015 Dec;36(12):2285-91. doi: 10.3174/ajnr.A4453. Epub 2015 Oct 15.


Validation of the 9-Point and 24-Point Hematoma Expansion Prediction Scores and Derivation of the PREDICT A/B Scores.

Huynh TJ, Aviv RI, Dowlatshahi D, Gladstone DJ, Laupacis A, Kiss A, Hill MD, Molina CA, Rodriguez-Luna D, Dzialowski I, Silva Y, Kobayashi A, Lum C, Boulanger JM, Gubitz G, Bhatia R, Padma V, Roy J, Kase CS, Symons SP, Demchuk AM; PREDICT/Sunnybrook CTA Investigators.

Stroke. 2015 Nov;46(11):3105-10. doi: 10.1161/STROKEAHA.115.009893. Epub 2015 Oct 13.


Intracerebral Hematoma Morphologic Appearance on Noncontrast Computed Tomography Predicts Significant Hematoma Expansion.

Blacquiere D, Demchuk AM, Al-Hazzaa M, Deshpande A, Petrcich W, Aviv RI, Rodriguez-Luna D, Molina CA, Silva Blas Y, Dzialowski I, Czlonkowska A, Boulanger JM, Lum C, Gubitz G, Padma V, Roy J, Kase CS, Bhatia R, Hill MD, Dowlatshahi D; PREDICT/Sunnybrook ICH CTA Study Group.

Stroke. 2015 Nov;46(11):3111-6. doi: 10.1161/STROKEAHA.115.010566. Epub 2015 Oct 8.


Non Tumor Perfusion Changes Following Stereotactic Radiosurgery to Brain Metastases.

Jakubovic R, Sahgal A, Ruschin M, Pejović-Milić A, Milwid R, Aviv RI.

Technol Cancer Res Treat. 2015 Aug;14(4):497-503. doi: 10.1177/1533034614600279.

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