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The effect of l-thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures. Aviñó A et al. Biochim Biophys Acta Gen Subj. (2017)

Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers. Tintoré M et al. Int J Mol Sci. (2015)

User Evaluation of Neonatology Ward Design. Trujillo JL et al. HERD. (2017)

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Items: 1 to 50 of 154


The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting.

Pan J, McKenzie ZM, D'Avino AR, Mashtalir N, Lareau CA, St Pierre R, Wang L, Shilatifard A, Kadoch C.

Nat Genet. 2019 Mar 11. doi: 10.1038/s41588-019-0363-5. [Epub ahead of print]


Nasopharingeal bacterial and fungal colonization in HIV-positive versus HIV-negative adults.

Rossetti B, Lombardi F, Belmonti S, D'Andrea MM, Tordini G, D'Avino A, Borghetti A, Moschese D, De Luca A, Montagnani F.

New Microbiol. 2019 Jan 23;42(1). [Epub ahead of print]


Changes in bone mineral density in HIV-positive, virologically suppressed patients switching to lamivudine/dolutegravir dual therapy: preliminary results from clinical practice.

Ciccullo A, D'Avino A, Lassandro AP, Baldin G, Borghetti A, Dusina A, Emiliozzi A, Gagliardini R, Moschese D, Belmonti S, Lombardi F, Di Giambenedetto S.

Infez Med. 2018 Dec 1;26(4):336-340.


A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.

Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM, Pan J, Remillard DI, Lareau CA, Zullow HJ, Fortoul N, Gray NS, Bradner JE, Chan HM, Kadoch C.

Nat Cell Biol. 2018 Dec;20(12):1410-1420. doi: 10.1038/s41556-018-0221-1. Epub 2018 Nov 5.


Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes.

Mashtalir N, D'Avino AR, Michel BC, Luo J, Pan J, Otto JE, Zullow HJ, McKenzie ZM, Kubiak RL, St Pierre R, Valencia AM, Poynter SJ, Cassel SH, Ranish JA, Kadoch C.

Cell. 2018 Nov 15;175(5):1272-1288.e20. doi: 10.1016/j.cell.2018.09.032. Epub 2018 Oct 18.


Selective depletion of metastatic stem cells as therapy for human colorectal cancer.

Céspedes MV, Unzueta U, Aviñó A, Gallardo A, Álamo P, Sala R, Sánchez-Chardi A, Casanova I, Mangues MA, Lopez-Pousa A, Eritja R, Villaverde A, Vázquez E, Mangues R.

EMBO Mol Med. 2018 Oct;10(10). pii: e8772. doi: 10.15252/emmm.201708772.


Label-free DNA-methylation detection by direct ds-DNA fragment screening using poly-purine hairpins.

Huertas CS, Aviñó A, Kurachi C, Piqué A, Sandoval J, Eritja R, Esteller M, Lechuga LM.

Biosens Bioelectron. 2018 Nov 30;120:47-54. doi: 10.1016/j.bios.2018.08.027. Epub 2018 Aug 15.


Naturally occurring quaternary benzo[c]phenanthridine alkaloids selectively stabilize G-quadruplexes.

Jarosova P, Paroulek P, Rajecky M, Rajecka V, Taborska E, Eritja R, Aviñó A, Mazzini S, Gargallo R, Taborsky P.

Phys Chem Chem Phys. 2018 Aug 22;20(33):21772-21782. doi: 10.1039/c8cp02681e.


Study of light-induced formation of photodimers in the i-motif nucleic acid structure by rapid-scan FTIR difference spectroscopy and hybrid hard- and soft-modelling.

Benabou S, Ruckebusch C, Sliwa M, Aviñó A, Eritja R, Gargallo R, de Juan A.

Phys Chem Chem Phys. 2018 Jul 25;20(29):19635-19646. doi: 10.1039/c8cp00850g.


Multiple Multicomponent Reactions: Unexplored Substrates, Selective Processes, and Versatile Chemotypes in Biomedicine.

Ghashghaei O, Caputo S, Sintes M, Revés M, Kielland N, Estarellas C, Luque FJ, Aviñó A, Eritja R, Serna-Gallego A, Marrugal-Lorenzo JA, Pachón J, Sánchez-Céspedes J, Treadwell R, de Moliner F, Vendrell M, Lavilla R.

Chemistry. 2018 Sep 25;24(54):14513-14521. doi: 10.1002/chem.201802877. Epub 2018 Aug 28.


The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma.

McBride MJ, Pulice JL, Beird HC, Ingram DR, D'Avino AR, Shern JF, Charville GW, Hornick JL, Nakayama RT, Garcia-Rivera EM, Araujo DM, Wang WL, Tsai JW, Yeagley M, Wagner AJ, Futreal PA, Khan J, Lazar AJ, Kadoch C.

Cancer Cell. 2018 Jun 11;33(6):1128-1141.e7. doi: 10.1016/j.ccell.2018.05.002. Epub 2018 May 31.


Glucose-nucleobase pairs within DNA: impact of hydrophobicity, alternative linking unit and DNA polymerase nucleotide insertion studies.

Vengut-Climent E, Peñalver P, Lucas R, Gómez-Pinto I, Aviñó A, Muro-Pastor AM, Galbis E, de Paz MV, Fonseca Guerra C, Bickelhaupt FM, Eritja R, González C, Morales JC.

Chem Sci. 2018 Mar 5;9(14):3544-3554. doi: 10.1039/c7sc04850e. eCollection 2018 Apr 14.


Exploring PAZ/3'-overhang interaction to improve siRNA specificity. A combined experimental and modeling study.

Alagia A, Jorge AF, Aviñó A, Cova TFGG, Crehuet R, Grijalvo S, Pais AACC, Eritja R.

Chem Sci. 2018 Jan 15;9(8):2074-2086. doi: 10.1039/c8sc00010g. eCollection 2018 Feb 28.


Atazanavir/ritonavir with lamivudine as maintenance therapy in virologically suppressed HIV-infected patients: 96 week outcomes of a randomized trial.

Fabbiani M, Gagliardini R, Ciccarelli N, Quiros Roldan E, Latini A, d'Ettorre G, Antinori A, Castagna A, Orofino G, Francisci D, Chinello P, Madeddu G, Grima P, Rusconi S, Del Pin B, Lombardi F, D'Avino A, Focà E, Colafigli M, Cauda R, Di Giambenedetto S, De Luca A; ATLAS-M Study Group .

J Antimicrob Chemother. 2018 Jul 1;73(7):1955-1964. doi: 10.1093/jac/dky123.


siRNA Modified with 2'-Deoxy-2'-C-methylpyrimidine Nucleosides.

Dellafiore M, Aviñó A, Alagia A, Montserrat JM, Iribarren AM, Eritja R.

Chembiochem. 2018 Jul 4;19(13):1409-1413. doi: 10.1002/cbic.201800077. Epub 2018 May 30.


DNA-based nanoscaffolds as vehicles for 5-fluoro-2'-deoxyuridine oligomers in colorectal cancer therapy.

Jorge AF, Aviñó A, Pais AACC, Eritja R, Fàbrega C.

Nanoscale. 2018 Apr 19;10(15):7238-7249. doi: 10.1039/c7nr08442k.


Evaluation of the effect of polymorphism on G-quadruplex-ligand interaction by means of spectroscopic and chromatographic techniques.

Benito S, Ferrer A, Benabou S, Aviñó A, Eritja R, Gargallo R.

Spectrochim Acta A Mol Biomol Spectrosc. 2018 May 5;196:185-195. doi: 10.1016/j.saa.2018.02.006. Epub 2018 Feb 6.


Switch to maraviroc with darunavir/r, both QD, in patients with suppressed HIV-1 was well tolerated but virologically inferior to standard antiretroviral therapy: 48-week results of a randomized trial.

Rossetti B, Gagliardini R, Meini G, Sterrantino G, Colangeli V, Re MC, Latini A, Colafigli M, Vignale F, Rusconi S, Micheli V, Di Biagio A, Orofino G, Ghisetti V, Fantauzzi A, Vullo V, Grima P, Francisci D, Mastroianni C, Antinori A, Trezzi M, Lisi L, Navarra P, Canovari B, D'Arminio Monforte A, Lamonica S, D'Avino A, Zazzi M, Di Giambenedetto S, De Luca A; for GUSTA trial study group.

PLoS One. 2017 Nov 21;12(11):e0187393. doi: 10.1371/journal.pone.0187393. eCollection 2017.


Comparison of NMR and crystal structures of membrane proteins and computational refinement to improve model quality.

Koehler Leman J, D'Avino AR, Bhatnagar Y, Gray JJ.

Proteins. 2018 Jan;86(1):57-74. doi: 10.1002/prot.25402. Epub 2017 Nov 8.


Clinical Improvement of Subacute and Chronic Otitis Media With Effusion Treated With Hyaluronic Acid Plus Hypertonic Solution via Nasal Lavage: A Randomized Controlled Trial.

Cioffi L, Gallo P, D'Avino A, Carlomagno F, Aloi G, D'Onofrio A, Del Gaizo D, Giuliano M, De Franchis R, Sandomenico ML, Pecoraro A.

Glob Pediatr Health. 2017 Sep 1;4:2333794X17725983. doi: 10.1177/2333794X17725983. eCollection 2017.


3-Year efficacy and durability of simplification to single tablet regimens: a comparison between co-formulated efavirenz/emtricitabine/tenofovir and rilpivirine/emtricitabine/tenofovir.

Gagliardini R, Bandera A, Zaccarelli M, Sterrantino G, Latini A, D'Avino A, Lapadula G, Antinori A, Cauda R, De Luca A, Gori A, Di Giambenedetto S, Fabbiani M.

Antivir Ther. 2018;23(2):139-148. doi: 10.3851/IMP3188.


i-motif structures in long cytosine-rich sequences found upstream of the promoter region of the SMARCA4 gene.

Benabou S, Aviñó A, Lyonnais S, González C, Eritja R, De Juan A, Gargallo R.

Biochimie. 2017 Sep;140:20-33. doi: 10.1016/j.biochi.2017.06.005. Epub 2017 Jun 12.


Stabilization of Telomeric I-Motif Structures by (2'S)-2'-Deoxy-2'-C-Methylcytidine Residues.

Aviñó A, Dellafiore M, Gargallo R, González C, Iribarren AM, Montserrat J, Eritja R.

Chembiochem. 2017 Jun 19;18(12):1123-1128. doi: 10.1002/cbic.201700112. Epub 2017 May 15.


Lipid-lowering effect and changes in estimated cardiovascular risk after switching to a tenofovir-containing regimen for the treatment of HIV-infected patients.

Gagliardini R, Fabbiani M, Colafigli M, D'Avino A, Mondi A, Borghetti A, Lamonica S, Cauda R, De Luca A, Di Giambenedetto S.

J Chemother. 2017 Oct;29(5):299-307. doi: 10.1080/1120009X.2016.1269040. Epub 2016 Dec 26.


The effect of l-thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures.

Aviñó A, Mazzini S, Fàbrega C, Peñalver P, Gargallo R, Morales JC, Eritja R.

Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1205-1212. doi: 10.1016/j.bbagen.2016.09.030. Epub 2016 Oct 2.


The risk of late or advanced presentation of HIV infected patients is still high, associated factors evolve but impact on overall mortality is vanishing over calendar years: results from the Italian MASTER Cohort.

Raffetti E, Postorino MC, Castelli F, Casari S, Castelnuovo F, Maggiolo F, Di Filippo E, D'Avino A, Gori A, Ladisa N, Di Pietro M, Sighinolfi L, Zacchi F, Torti C.

BMC Public Health. 2016 Aug 25;16(1):878. doi: 10.1186/s12889-016-3477-z.


Controlling the Reversible Assembly of Liposomes through a Multistimuli Responsive Anchored DNA.

Hernández-Ainsa S, Ricci M, Hilton L, Aviñó A, Eritja R, Keyser UF.

Nano Lett. 2016 Jul 13;16(7):4462-6. doi: 10.1021/acs.nanolett.6b01618. Epub 2016 Jul 1.


Glucose-Nucleobase Pseudo Base Pairs: Biomolecular Interactions within DNA.

Vengut-Climent E, Gómez-Pinto I, Lucas R, Peñalver P, Aviñó A, Fonseca Guerra C, Bickelhaupt FM, Eritja R, González C, Morales JC.

Angew Chem Int Ed Engl. 2016 Jul 18;55(30):8643-7. doi: 10.1002/anie.201603510. Epub 2016 Jun 22.


Neuropsychological screening tools in Italian HIV+ patients: a comparison of Montreal Cognitive Assessment (MoCA) and Mini Mental State Examination (MMSE).

Milanini B, Ciccarelli N, Fabbiani M, Baldonero E, Limiti S, Gagliardini R, Borghetti A, D'Avino A, Mondi A, Colafigli M, Cauda R, Di Giambenedetto S.

Clin Neuropsychol. 2016 Jan-Dec;30(sup1):1457-1468. Epub 2016 May 16.


User Evaluation of Neonatology Ward Design.

Trujillo JL, Aviñó AM, Millán CL.

HERD. 2017 Jan;10(2):23-48. doi: 10.1177/1937586716641275. Epub 2016 Jul 8.


Virological control and metabolic improvement in HIV-infected, virologically suppressed patients switching to lamivudine/dolutegravir dual therapy.

Borghetti A, Baldin G, Ciccullo A, Gagliardini R, D'Avino A, Mondi A, Ciccarelli N, Lamonica S, Fanti I, Trecarichi E, Fabbiani M, Cauda R, De Luca A, Di Giambenedetto S.

J Antimicrob Chemother. 2016 Aug;71(8):2359-61. doi: 10.1093/jac/dkw147. Epub 2016 May 4. No abstract available.


A New Radiographic Classification for Distal Shaft Fifth Metatarsal Fractures.

Soave RL, Bleazey S, Rudowsky A, Clarke RV, Avino A Jr, Kuchar DJ.

J Foot Ankle Surg. 2016 Jul-Aug;55(4):803-7. doi: 10.1053/j.jfas.2016.03.001. Epub 2016 Apr 12.


The Effect of Small Cosolutes that Mimic Molecular Crowding Conditions on the Stability of Triplexes Involving Duplex DNA.

Aviñó A, Mazzini S, Gargallo R, Eritja R.

Int J Mol Sci. 2016 Feb 5;17(2):211. doi: 10.3390/ijms17020211.


Sensitive and label-free detection of miRNA-145 by triplex formation.

Aviñó A, Huertas CS, Lechuga LM, Eritja R.

Anal Bioanal Chem. 2016 Jan;408(3):885-93. doi: 10.1007/s00216-015-9180-6. Epub 2015 Nov 24.


Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers.

Tintoré M, Mazzini S, Polito L, Marelli M, Latorre A, Somoza Á, Aviñó A, Fàbrega C, Eritja R.

Int J Mol Sci. 2015 Nov 18;16(11):27625-39. doi: 10.3390/ijms161126046.


Efficacy and safety of treatment simplification to atazanavir/ritonavir + lamivudine in HIV-infected patients with virological suppression: 144 week follow-up of the AtLaS pilot study.

Mondi A, Fabbiani M, Ciccarelli N, Colafigli M, D'Avino A, Borghetti A, Gagliardini R, Cauda R, De Luca A, Di Giambenedetto S.

J Antimicrob Chemother. 2015;70(6):1843-9. doi: 10.1093/jac/dkv037. Epub 2015 Feb 26.


Video-assisted thoracoscopic implantation of a diaphragmatic pacemaker in a child with tetraplegia: indications, technique, and results.

Filho Pinto DR, Tedde ML, Avino AJ, Brandão SL, Zanatta I, Hahn R.

J Bras Pneumol. 2015 Jan-Feb;41(1):90-4. doi: 10.1590/S1806-37132015000100011.


Switching to lamivudine plus darunavir/r dual therapy in a cohort of treatment-experienced HIV-positive patients: the experience of an Italian centre.

Borghetti A, Mondi A, Piccoli B, Gagliardini R, Lamonica S, Ciccarelli N, D'Avino A, Pallavicini F, Cauda R, De Luca A, Fabbiani M, Di Giambenedetto S.

J Int AIDS Soc. 2014 Nov 2;17(4 Suppl 3):19817. doi: 10.7448/IAS.17.4.19817. eCollection 2014.


Liver fibrosis is associated with cognitive impairment in HIV-positive patients.

Ciccarelli N, Fabbiani M, Grima P, Limiti S, Fanti I, Mondi A, Gagliardini R, D'Avino A, Borghetti A, Cauda R, Di Giambenedetto S.

J Int AIDS Soc. 2014 Nov 2;17(4 Suppl 3):19722. doi: 10.7448/IAS.17.4.19722. eCollection 2014.


Prevalence of osteoporosis and predictors of low BMD in a cohort of HIV-1-infected patients in Rome: features of a population at high risk.

D'Avino A, Lassandro A, Lamonica S, Piccoli B, Fabbiani M, Mondi A, Gagliardini R, Borghetti A, Fanti I, Pallavicini F, Cauda R, Di Giambenedetto S.

J Int AIDS Soc. 2014 Nov 2;17(4 Suppl 3):19570. doi: 10.7448/IAS.17.4.19570. eCollection 2014.


Oligonucleotide delivery: a patent review (2010 - 2013).

Grijalvo S, Aviñó A, Eritja R.

Expert Opin Ther Pat. 2014 Jul;24(7):801-19. doi: 10.1517/13543776.2014.915944. Epub 2014 May 5. Review.


[Diagnosis and management of acute pharyngotonsillitis in the primary care pediatrician's office].

Vicedomini D, Lalinga G, Lugli N, D'Avino A.

Minerva Pediatr. 2014 Feb;66(1):69-76. Review. Italian.


Effects of sugar functional groups, hydrophobicity, and fluorination on carbohydrate-DNA stacking interactions in water.

Lucas R, Peñalver P, Gómez-Pinto I, Vengut-Climent E, Mtashobya L, Cousin J, Maldonado OS, Perez V, Reynes V, Aviñó A, Eritja R, González C, Linclau B, Morales JC.

J Org Chem. 2014 Mar 21;79(6):2419-29. doi: 10.1021/jo402700y. Epub 2014 Mar 5.


Ophthalmic artery resistance index is increased in HIV-Infected patients and is influenced by protease inhibitors exposure.

Fabbiani M, Grima P, Borghetti A, Colafigli M, D'Avino A, Mondi A, Gagliardini R, De Luca A, Cauda R, Di Giambenedetto S.

J Infect. 2014 May;68(5):500-3. doi: 10.1016/j.jinf.2014.01.012. Epub 2014 Feb 6. No abstract available.


Single tablet regimens are associated with reduced Efavirenz withdrawal in antiretroviral therapy naïve or switching for simplification HIV-infected patients.

Fabbiani M, Zaccarelli M, Grima P, Prosperi M, Fanti I, Colafigli M, D'Avino A, Mondi A, Borghetti A, Fantoni M, Cauda R, Di Giambenedetto S.

BMC Infect Dis. 2014 Jan 13;14:26. doi: 10.1186/1471-2334-14-26.


Specific loop modifications of the thrombin-binding aptamer trigger the formation of parallel structures.

Aviñó A, Portella G, Ferreira R, Gargallo R, Mazzini S, Gabelica V, Orozco M, Eritja R.

FEBS J. 2014 Feb;281(4):1085-99. doi: 10.1111/febs.12670. Epub 2014 Jan 2.


Safety and efficacy of treatment switch to raltegravir plus tenofovir/emtricitabine or abacavir/lamivudine in patients with optimal virological control: 48-week results from a randomized pilot study (Raltegravir Switch for Toxicity or Adverse Events, RASTA Study).

Fabbiani M, Mondi A, Colafigli M, D'Ettorre G, Paoletti F, D'Avino A, Ciccarelli N, Sidella L, Murri R, Fortuna S, Vullo V, Cauda R, De Luca A, Di Giambenedetto S.

Scand J Infect Dis. 2014 Jan;46(1):34-45. doi: 10.3109/00365548.2013.840920. Epub 2013 Oct 28.


Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops.

Benabou S, Ferreira R, Aviñó A, González C, Lyonnais S, Solà M, Eritja R, Jaumot J, Gargallo R.

Biochim Biophys Acta. 2014 Jan;1840(1):41-52. doi: 10.1016/j.bbagen.2013.08.028. Epub 2013 Sep 6.


The association of high-sensitivity c-reactive protein and other biomarkers with cardiovascular disease in patients treated for HIV: a nested case-control study.

De Luca A, de Gaetano Donati K, Colafigli M, Cozzi-Lepri A, De Curtis A, Gori A, Sighinolfi L, Giacometti A, Capobianchi MR, D'Avino A, Iacoviello L, Cauda R, D'Arminio Monforte A.

BMC Infect Dis. 2013 Sep 3;13:414. doi: 10.1186/1471-2334-13-414.


An aptamer-gated silica mesoporous material for thrombin detection.

Oroval M, Climent E, Coll C, Eritja R, Aviñó A, Marcos MD, Sancenón F, Martínez-Máñez R, Amorós P.

Chem Commun (Camb). 2013 Jun 18;49(48):5480-2. doi: 10.1039/c3cc42157k. Epub 2013 May 10.


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