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Items: 1 to 50 of 280

1.

Overview of Next-Generation Sequencing Technologies.

Slatko BE, Gardner AF, Ausubel FM.

Curr Protoc Mol Biol. 2018 Apr;122(1):e59. doi: 10.1002/cpmb.59.

PMID:
29851291
2.

Replication of the Ordered, Nonredundant Library of Pseudomonas aeruginosa strain PA14 Transposon Insertion Mutants.

Drenkard E, Hibbler RM, Gutu DA, Eaton AD, Silverio AL, Ausubel FM, Hurley BP, Yonker LM.

J Vis Exp. 2018 May 4;(135). doi: 10.3791/57298.

PMID:
29781996
3.

A new class of synthetic retinoid antibiotics effective against bacterial persisters.

Kim W, Zhu W, Hendricks GL, Van Tyne D, Steele AD, Keohane CE, Fricke N, Conery AL, Shen S, Pan W, Lee K, Rajamuthiah R, Fuchs BB, Vlahovska PM, Wuest WM, Gilmore MS, Gao H, Ausubel FM, Mylonakis E.

Nature. 2018 Apr 5;556(7699):103-107. doi: 10.1038/nature26157. Epub 2018 Mar 28.

PMID:
29590091
4.

Quorum-sensing regulator RhlR but not its autoinducer RhlI enables Pseudomonas to evade opsonization.

Haller S, Franchet A, Hakkim A, Chen J, Drenkard E, Yu S, Schirmeier S, Li Z, Martins N, Ausubel FM, Liégeois S, Ferrandon D.

EMBO Rep. 2018 May;19(5). pii: e44880. doi: 10.15252/embr.201744880. Epub 2018 Mar 9.

PMID:
29523648
5.

Both live and dead Enterococci activate Caenorhabditis elegans host defense via immune and stress pathways.

Yuen GJ, Ausubel FM.

Virulence. 2018 Dec 31;9(1):683-699. doi: 10.1080/21505594.2018.1438025.

6.

Rhizosphere-associated Pseudomonas induce systemic resistance to herbivores at the cost of susceptibility to bacterial pathogens.

Haney CH, Wiesmann CL, Shapiro LR, Melnyk RA, O'Sullivan LR, Khorasani S, Xiao L, Han J, Bush J, Carrillo J, Pierce NE, Ausubel FM.

Mol Ecol. 2018 Apr;27(8):1833-1847. doi: 10.1111/mec.14400. Epub 2017 Nov 23.

PMID:
29087012
7.

An Antipersister Strategy for Treatment of Chronic Pseudomonas aeruginosa Infections.

Koeva M, Gutu AD, Hebert W, Wager JD, Yonker LM, O'Toole GA, Ausubel FM, Moskowitz SM, Joseph-McCarthy D.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e00987-17. doi: 10.1128/AAC.00987-17. Print 2017 Dec.

8.

Investment in secreted enzymes during nutrient-limited growth is utility dependent.

Cezairliyan B, Ausubel FM.

Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):E7796-E7802. doi: 10.1073/pnas.1708580114. Epub 2017 Aug 28.

9.

Characterization of a Francisella tularensis-Caenorhabditis elegans Pathosystem for the Evaluation of Therapeutic Compounds.

Jayamani E, Tharmalingam N, Rajamuthiah R, Coleman JJ, Kim W, Okoli I, Hernandez AM, Lee K, Nau GJ, Ausubel FM, Mylonakis E.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00310-17. doi: 10.1128/AAC.00310-17. Print 2017 Sep.

10.

The NBS-LRR architectures of plant R-proteins and metazoan NLRs evolved in independent events.

Urbach JM, Ausubel FM.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1063-1068. doi: 10.1073/pnas.1619730114. Epub 2017 Jan 17.

11.

Influence of maternal breast milk ingestion on acquisition of the intestinal microbiome in preterm infants.

Gregory KE, Samuel BS, Houghteling P, Shan G, Ausubel FM, Sadreyev RI, Walker WA.

Microbiome. 2016 Dec 30;4(1):68. doi: 10.1186/s40168-016-0214-x.

12.

Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway.

McEwan DL, Feinbaum RL, Stroustrup N, Haas W, Conery AL, Anselmo A, Sadreyev R, Ausubel FM.

BMC Biol. 2016 Dec 7;14(1):105.

13.

Introduction to Gene Editing and Manipulation Using CRISPR/Cas9 Technology.

Newman M, Ausubel FM.

Curr Protoc Mol Biol. 2016 Jul 1;115:31.4.1-6. doi: 10.1002/cpmb.14. Review.

14.

Mutation of the Glucosinolate Biosynthesis Enzyme Cytochrome P450 83A1 Monooxygenase Increases Camalexin Accumulation and Powdery Mildew Resistance.

Liu S, Bartnikas LM, Volko SM, Ausubel FM, Tang D.

Front Plant Sci. 2016 Mar 2;7:227. doi: 10.3389/fpls.2016.00227. eCollection 2016.

15.

NH125 kills methicillin-resistant Staphylococcus aureus persisters by lipid bilayer disruption.

Kim W, Fricke N, Conery AL, Fuchs BB, Rajamuthiah R, Jayamani E, Vlahovska PM, Ausubel FM, Mylonakis E.

Future Med Chem. 2016;8(3):257-69. doi: 10.4155/fmc.15.189. Epub 2016 Feb 24.

16.

On the Mechanism of Berberine-INF55 (5-Nitro-2-phenylindole) Hybrid Antibacterials.

Dolla NK, Chen C, Larkins-Ford J, Rajamuthiah R, Jagadeesan S, Conery AL, Ausubel FM, Mylonakis E, Bremner JB, Lewis K, Kelso MJ.

Aust J Chem. 2015;67:1471-1480.

17.

Antibacterial properties of 3-(phenylsulfonyl)-2-pyrazinecarbonitrile.

Rajamuthiah R, Jayamani E, Majed H, Conery AL, Kim W, Kwon B, Fuchs BB, Kelso MJ, Ausubel FM, Mylonakis E.

Bioorg Med Chem Lett. 2015 Nov 15;25(22):5203-7. doi: 10.1016/j.bmcl.2015.09.066. Epub 2015 Sep 30.

18.

Enhancing immunity by engineering DAMPs.

Cervone F, Ausubel FM, De Lorenzo G.

Oncotarget. 2015 Oct 6;6(30):28523-4. doi: 10.18632/oncotarget.5251. No abstract available.

19.

MICROBIOME. Plant microbiome blueprints.

Haney CH, Ausubel FM.

Science. 2015 Aug 21;349(6250):788-9. doi: 10.1126/science.aad0092. No abstract available.

PMID:
26293938
20.

Pseudomonas syringae enhances herbivory by suppressing the reactive oxygen burst in Arabidopsis.

Groen SC, Humphrey PT, Chevasco D, Ausubel FM, Pierce NE, Whiteman NK.

J Insect Physiol. 2016 Jan;84:90-102. doi: 10.1016/j.jinsphys.2015.07.011. Epub 2015 Jul 21.

21.

A Defensin from the Model Beetle Tribolium castaneum Acts Synergistically with Telavancin and Daptomycin against Multidrug Resistant Staphylococcus aureus.

Rajamuthiah R, Jayamani E, Conery AL, Fuchs BB, Kim W, Johnston T, Vilcinskas A, Ausubel FM, Mylonakis E.

PLoS One. 2015 Jun 10;10(6):e0128576. doi: 10.1371/journal.pone.0128576. eCollection 2015.

22.

Identification of an Antimicrobial Agent Effective against Methicillin-Resistant Staphylococcus aureus Persisters Using a Fluorescence-Based Screening Strategy.

Kim W, Conery AL, Rajamuthiah R, Fuchs BB, Ausubel FM, Mylonakis E.

PLoS One. 2015 Jun 3;10(6):e0127640. doi: 10.1371/journal.pone.0127640. eCollection 2015.

23.

Repurposing salicylanilide anthelmintic drugs to combat drug resistant Staphylococcus aureus.

Rajamuthiah R, Fuchs BB, Conery AL, Kim W, Jayamani E, Kwon B, Ausubel FM, Mylonakis E.

PLoS One. 2015 Apr 21;10(4):e0124595. doi: 10.1371/journal.pone.0124595. eCollection 2015.

24.

Plant immunity triggered by engineered in vivo release of oligogalacturonides, damage-associated molecular patterns.

Benedetti M, Pontiggia D, Raggi S, Cheng Z, Scaloni F, Ferrari S, Ausubel FM, Cervone F, De Lorenzo G.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5533-8. doi: 10.1073/pnas.1504154112. Epub 2015 Apr 13.

25.

Pathogen-secreted proteases activate a novel plant immune pathway.

Cheng Z, Li JF, Niu Y, Zhang XC, Woody OZ, Xiong Y, Djonović S, Millet Y, Bush J, McConkey BJ, Sheen J, Ausubel FM.

Nature. 2015 May 14;521(7551):213-6. doi: 10.1038/nature14243. Epub 2015 Mar 2.

26.

A new antibiotic with potent activity targets MscL.

Iscla I, Wray R, Blount P, Larkins-Ford J, Conery AL, Ausubel FM, Ramu S, Kavanagh A, Huang JX, Blaskovich MA, Cooper MA, Obregon-Henao A, Orme I, Tjandra ES, Stroeher UH, Brown MH, Macardle C, van Holst N, Ling Tong C, Slattery AD, Gibson CT, Raston CL, Boulos RA.

J Antibiot (Tokyo). 2015 Jul;68(7):453-62. doi: 10.1038/ja.2015.4. Epub 2015 Feb 4.

27.

Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa.

Kirienko NV, Ausubel FM, Ruvkun G.

Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1821-6. doi: 10.1073/pnas.1424954112. Epub 2015 Jan 26.

28.

Insect-derived cecropins display activity against Acinetobacter baumannii in a whole-animal high-throughput Caenorhabditis elegans model.

Jayamani E, Rajamuthiah R, Larkins-Ford J, Fuchs BB, Conery AL, Vilcinskas A, Ausubel FM, Mylonakis E.

Antimicrob Agents Chemother. 2015 Mar;59(3):1728-37. doi: 10.1128/AAC.04198-14. Epub 2015 Jan 12.

29.

Jasmonate signalling in Arabidopsis involves SGT1b-HSP70-HSP90 chaperone complexes.

Zhang XC, Millet YA, Cheng Z, Bush J, Ausubel FM.

Nat Plants. 2015;1. pii: 15049. Epub 2015 Apr 27.

30.

Associations with rhizosphere bacteria can confer an adaptive advantage to plants.

Haney CH, Samuel BS, Bush J, Ausubel FM.

Nat Plants. 2015;1(6). pii: 15051. Epub 2015 May 11.

31.

Twists and turns: my career path and concerns about the future.

Ausubel FM.

Genetics. 2014 Oct;198(2):431-4. doi: 10.1534/genetics.114.169102.

32.

Next-Gen Sequencing-Based Mapping and Identification of Ethyl Methanesulfonate-Induced Mutations in Arabidopsis thaliana.

Zhang XC, Millet Y, Ausubel FM, Borowsky M.

Curr Protoc Mol Biol. 2014 Oct 1;108:7.18.1-16. doi: 10.1002/0471142727.mb0718s108.

PMID:
25271717
33.

Apoplastic peroxidases are required for salicylic acid-mediated defense against Pseudomonas syringae.

Mammarella ND, Cheng Z, Fu ZQ, Daudi A, Bolwell GP, Dong X, Ausubel FM.

Phytochemistry. 2015 Apr;112:110-21. doi: 10.1016/j.phytochem.2014.07.010. Epub 2014 Aug 2.

34.

The evolutionarily conserved mediator subunit MDT-15/MED15 links protective innate immune responses and xenobiotic detoxification.

Pukkila-Worley R, Feinbaum RL, McEwan DL, Conery AL, Ausubel FM.

PLoS Pathog. 2014 May 29;10(5):e1004143. doi: 10.1371/journal.ppat.1004143. eCollection 2014 May.

35.

Pseudomonas aeruginosa PA14 pathogenesis in Caenorhabditis elegans.

Kirienko NV, Cezairliyan BO, Ausubel FM, Powell JR.

Methods Mol Biol. 2014;1149:653-69. doi: 10.1007/978-1-4939-0473-0_50.

PMID:
24818940
36.

High-throughput screening for novel anti-infectives using a C. elegans pathogenesis model.

Conery AL, Larkins-Ford J, Ausubel FM, Kirienko NV.

Curr Protoc Chem Biol. 2014 Mar 14;6(1):25-37. doi: 10.1002/9780470559277.ch130160.

37.

Pathogenesis and Models of Enterococcal Infection.

Garsin DA, Frank KL, Silanpää J, Ausubel FM, Hartke A, Shankar N, Murray BE.

In: Gilmore MS, Clewell DB, Ike Y, Shankar N, editors. Enterococci: From Commensals to Leading Causes of Drug Resistant Infection [Internet]. Boston: Massachusetts Eye and Ear Infirmary; 2014-.
2014 Feb 7.

38.

Whole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureus.

Rajamuthiah R, Fuchs BB, Jayamani E, Kim Y, Larkins-Ford J, Conery A, Ausubel FM, Mylonakis E.

PLoS One. 2014 Feb 19;9(2):e89189. doi: 10.1371/journal.pone.0089189. eCollection 2014.

39.

Enterococcus infection biology: lessons from invertebrate host models.

Yuen GJ, Ausubel FM.

J Microbiol. 2014 Mar;52(3):200-10. doi: 10.1007/s12275-014-4011-6. Epub 2014 Mar 1. Review.

40.

Virulence profile: Frederick M Ausubel.

Ausubel FM.

Virulence. 2013 Nov 15;4(8):730-3. doi: 10.4161/viru.26579. No abstract available.

41.

Pathogen-triggered ethylene signaling mediates systemic-induced susceptibility to herbivory in Arabidopsis.

Groen SC, Whiteman NK, Bahrami AK, Wilczek AM, Cui J, Russell JA, Cibrian-Jaramillo A, Butler IA, Rana JD, Huang GH, Bush J, Ausubel FM, Pierce NE.

Plant Cell. 2013 Nov;25(11):4755-66. doi: 10.1105/tpc.113.113415. Epub 2013 Nov 27.

42.

Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death.

Kirienko NV, Kirienko DR, Larkins-Ford J, Wählby C, Ruvkun G, Ausubel FM.

Cell Host Microbe. 2013 Apr 17;13(4):406-16. doi: 10.1016/j.chom.2013.03.003.

43.

Trehalose biosynthesis promotes Pseudomonas aeruginosa pathogenicity in plants.

Djonović S, Urbach JM, Drenkard E, Bush J, Feinbaum R, Ausubel JL, Traficante D, Risech M, Kocks C, Fischbach MA, Priebe GP, Ausubel FM.

PLoS Pathog. 2013 Mar;9(3):e1003217. doi: 10.1371/journal.ppat.1003217. Epub 2013 Mar 7.

44.

Identification of Pseudomonas aeruginosa phenazines that kill Caenorhabditis elegans.

Cezairliyan B, Vinayavekhin N, Grenfell-Lee D, Yuen GJ, Saghatelian A, Ausubel FM.

PLoS Pathog. 2013 Jan;9(1):e1003101. doi: 10.1371/journal.ppat.1003101. Epub 2013 Jan 3.

45.

FLS2-mediated responses to Ax21-derived peptides: response to the Mueller et al. commentary.

Danna CH, Zhang XC, Khatri A, Bent AF, Ronald PC, Ausubel FM.

Plant Cell. 2012 Aug;24(8):3174-6. Epub 2012 Aug 24. No abstract available.

46.

Genome-wide identification of Pseudomonas aeruginosa virulence-related genes using a Caenorhabditis elegans infection model.

Feinbaum RL, Urbach JM, Liberati NT, Djonovic S, Adonizio A, Carvunis AR, Ausubel FM.

PLoS Pathog. 2012;8(7):e1002813. doi: 10.1371/journal.ppat.1002813. Epub 2012 Jul 26.

47.

Genes involved in the evolution of herbivory by a leaf-mining, Drosophilid fly.

Whiteman NK, Gloss AD, Sackton TB, Groen SC, Humphrey PT, Lapoint RT, Sønderby IE, Halkier BA, Kocks C, Ausubel FM, Pierce NE.

Genome Biol Evol. 2012;4(9):900-16. doi: 10.1093/gbe/evs063. Epub 2012 Jul 19.

48.

Perception of volatiles produced by UVC-irradiated plants alters the response to viral infection in naïve neighboring plants.

Yao Y, Danna CH, Ausubel FM, Kovalchuk I.

Plant Signal Behav. 2012 Jul;7(7):741-5. doi: 10.4161/psb.20406. Epub 2012 Jul 1.

49.

Stimulation of host immune defenses by a small molecule protects C. elegans from bacterial infection.

Pukkila-Worley R, Feinbaum R, Kirienko NV, Larkins-Ford J, Conery AL, Ausubel FM.

PLoS Genet. 2012;8(6):e1002733. doi: 10.1371/journal.pgen.1002733. Epub 2012 Jun 14.

50.

An image analysis toolbox for high-throughput C. elegans assays.

Wählby C, Kamentsky L, Liu ZH, Riklin-Raviv T, Conery AL, O'Rourke EJ, Sokolnicki KL, Visvikis O, Ljosa V, Irazoqui JE, Golland P, Ruvkun G, Ausubel FM, Carpenter AE.

Nat Methods. 2012 Apr 22;9(7):714-6. doi: 10.1038/nmeth.1984.

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