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Items: 1 to 50 of 91

1.

Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation.

Austin JW, Buckner CM, Kardava L, Wang W, Zhang X, Melson VA, Swanson RG, Martins AJ, Zhou JQ, Hoehn KB, Fisk JN, Dimopoulos Y, Chassiakos A, O'Dell S, Smelkinson MG, Seamon CA, Kwan RW, Sneller MC, Pittaluga S, Doria-Rose NA, McDermott A, Li Y, Chun TW, Kleinstein SH, Tsang JS, Petrovas C, Moir S.

Sci Transl Med. 2019 Nov 27;11(520). pii: eaax0904. doi: 10.1126/scitranslmed.aax0904.

PMID:
31776286
2.

IgG3 regulates tissue-like memory B cells in HIV-infected individuals.

Kardava L, Sohn H, Youn C, Austin JW, Wang W, Buckner CM, Justement JS, Melson VA, Roth GE, Hand MA, Gittens KR, Kwan RW, Sneller MC, Li Y, Chun TW, Sun PD, Pierce SK, Moir S.

Nat Immunol. 2018 Sep;19(9):1001-1012. doi: 10.1038/s41590-018-0180-5. Epub 2018 Aug 13.

3.

It's not all about the honey.

Siu K, Rehan M, Austin JW, Ramachandran Nair R, Pernica J.

Paediatr Child Health. 2017 Mar;22(1):37-38. doi: 10.1093/pch/pxx009. Epub 2017 Mar 30. No abstract available.

4.

Tracking sources of Clostridium botulinum type E contamination in seal meat.

Leclair D, Farber JM, Pagotto F, Suppa S, Doidge B, Austin JW.

Int J Circumpolar Health. 2017;76(1):1380994. doi: 10.1080/22423982.2017.1380994.

5.

The molecular signature of murine T cell homeostatic proliferation reveals both inflammatory and immune inhibition patterns.

Fortner KA, Bond JP, Austin JW, Boss JM, Budd RC.

J Autoimmun. 2017 Aug;82:47-61. doi: 10.1016/j.jaut.2017.05.003. Epub 2017 May 24.

6.

Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature.

Peck MW, Smith TJ, Anniballi F, Austin JW, Bano L, Bradshaw M, Cuervo P, Cheng LW, Derman Y, Dorner BG, Fisher A, Hill KK, Kalb SR, Korkeala H, Lindström M, Lista F, Lúquez C, Mazuet C, Pirazzini M, Popoff MR, Rossetto O, Rummel A, Sesardic D, Singh BR, Stringer SC.

Toxins (Basel). 2017 Jan 18;9(1). pii: E38. doi: 10.3390/toxins9010038. Review.

7.

Genetic and Epigenetic Regulation of PD-1 Expression.

Bally AP, Austin JW, Boss JM.

J Immunol. 2016 Mar 15;196(6):2431-7. doi: 10.4049/jimmunol.1502643. Review.

8.

Evolution of Chromosomal Clostridium botulinum Type E Neurotoxin Gene Clusters: Evidence Provided by Their Rare Plasmid-Borne Counterparts.

Carter AT, Austin JW, Weedmark KA, Peck MW.

Genome Biol Evol. 2016 Mar 2;8(3):540-55. doi: 10.1093/gbe/evw017.

9.

Clostridium botulinum Group II Isolate Phylogenomic Profiling Using Whole-Genome Sequence Data.

Weedmark KA, Mabon P, Hayden KL, Lambert D, Van Domselaar G, Austin JW, Corbett CR.

Appl Environ Microbiol. 2015 Sep 1;81(17):5938-48. doi: 10.1128/AEM.01155-15. Epub 2015 Jun 26.

10.

NF-κB regulates PD-1 expression in macrophages.

Bally AP, Lu P, Tang Y, Austin JW, Scharer CD, Ahmed R, Boss JM.

J Immunol. 2015 May 1;194(9):4545-54. doi: 10.4049/jimmunol.1402550. Epub 2015 Mar 25.

11.

Do Size and Insecticide Treatment Matter? Evaluation of Different Nets against Phlebotomus argentipes, the Vector of Visceral Leishmaniasis in Nepal.

Das ML, Rowland M, Austin JW, De Lazzari E, Picado A.

PLoS One. 2014 Dec 10;9(12):e114915. doi: 10.1371/journal.pone.0114915. eCollection 2014.

12.

Outbreak of type E foodborne botulism linked to traditionally prepared salted fish in Ontario, Canada.

Walton RN, Clemens A, Chung J, Moore S, Wharton D, Haydu L, de Villa E, Sanders G, Bussey J, Richardson D, Austin JW.

Foodborne Pathog Dis. 2014 Oct;11(10):830-4. doi: 10.1089/fpd.2014.1783. Epub 2014 Sep 4.

PMID:
25188279
13.

Two novel toxin variants revealed by whole-genome sequencing of 175 Clostridium botulinum type E strains.

Weedmark KA, Lambert DL, Mabon P, Hayden KL, Urfano CJ, Leclair D, Van Domselaar G, Austin JW, Corbett CR.

Appl Environ Microbiol. 2014 Oct;80(20):6334-45. doi: 10.1128/AEM.01573-14. Epub 2014 Aug 8.

14.

Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types.

Lohsen S, Majumder P, Scharer CD, Barwick BG, Austin JW, Zinzow-Kramer WM, Boss JM.

Genes Immun. 2014 Dec;15(8):543-55. doi: 10.1038/gene.2014.49. Epub 2014 Aug 7.

15.

Three classes of plasmid (47-63 kb) carry the type B neurotoxin gene cluster of group II Clostridium botulinum.

Carter AT, Austin JW, Weedmark KA, Corbett C, Peck MW.

Genome Biol Evol. 2014 Aug;6(8):2076-87. doi: 10.1093/gbe/evu164.

16.

STAT3, STAT4, NFATc1, and CTCF regulate PD-1 through multiple novel regulatory regions in murine T cells.

Austin JW, Lu P, Majumder P, Ahmed R, Boss JM.

J Immunol. 2014 May 15;192(10):4876-86. doi: 10.4049/jimmunol.1302750. Epub 2014 Apr 7.

17.

Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection.

Lu P, Youngblood BA, Austin JW, Mohammed AU, Butler R, Ahmed R, Boss JM.

J Exp Med. 2014 Mar 10;211(3):515-27. doi: 10.1084/jem.20130208. Epub 2014 Mar 3.

18.

Riluzole attenuates neuropathic pain and enhances functional recovery in a rodent model of cervical spondylotic myelopathy.

Moon ES, Karadimas SK, Yu WR, Austin JW, Fehlings MG.

Neurobiol Dis. 2014 Feb;62:394-406. doi: 10.1016/j.nbd.2013.10.020. Epub 2013 Oct 29.

PMID:
24184328
19.

Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells.

Youngblood B, Noto A, Porichis F, Akondy RS, Ndhlovu ZM, Austin JW, Bordi R, Procopio FA, Miura T, Allen TM, Sidney J, Sette A, Walker BD, Ahmed R, Boss JM, Sékaly RP, Kaufmann DE.

J Immunol. 2013 Jul 15;191(2):540-4. doi: 10.4049/jimmunol.1203161. Epub 2013 Jun 14.

20.

Foodborne botulism in Canada, 1985-2005.

Leclair D, Fung J, Isaac-Renton JL, Proulx JF, May-Hadford J, Ellis A, Ashton E, Bekal S, Farber JM, Blanchfield B, Austin JW.

Emerg Infect Dis. 2013 Jun;19(6):961-8. doi: 10.3201/eid1906.120873.

21.

Individual characteristics and management decisions affect outcome of anticoagulated patients with intracranial hemorrhage.

Hawryluk GW, Furlan JC, Austin JW, Fehlings MG.

World Neurosurg. 2014 May-Jun;81(5-6):742-51. doi: 10.1016/j.wneu.2013.01.080. Epub 2013 Jan 19. Review.

PMID:
23336984
22.

Distribution of Clostridium botulinum type E strains in Nunavik, Northern Quebec, Canada.

Leclair D, Farber JM, Doidge B, Blanchfield B, Suppa S, Pagotto F, Austin JW.

Appl Environ Microbiol. 2013 Jan;79(2):646-54. doi: 10.1128/AEM.05999-11. Epub 2012 Nov 16.

23.

Immunoglobulin G (IgG) attenuates neuroinflammation and improves neurobehavioral recovery after cervical spinal cord injury.

Nguyen DH, Cho N, Satkunendrarajah K, Austin JW, Wang J, Fehlings MG.

J Neuroinflammation. 2012 Sep 21;9:224. doi: 10.1186/1742-2094-9-224.

24.

Constipation and poor feeding in an infant with botulism.

Schwartz KL, Austin JW, Science M.

CMAJ. 2012 Nov 20;184(17):1919-22. doi: 10.1503/cmaj.120340. Epub 2012 Sep 17. No abstract available.

25.

The relationship between localized subarachnoid inflammation and parenchymal pathophysiology after spinal cord injury.

Austin JW, Afshar M, Fehlings MG.

J Neurotrauma. 2012 Jul 1;29(10):1838-49. doi: 10.1089/neu.2012.2354.

26.

High molecular weight hyaluronan reduces lipopolysaccharide mediated microglial activation.

Austin JW, Gilchrist C, Fehlings MG.

J Neurochem. 2012 Jul;122(2):344-55. doi: 10.1111/j.1471-4159.2012.07789.x. Epub 2012 Jun 1.

27.

The effects of intrathecal injection of a hyaluronan-based hydrogel on inflammation, scarring and neurobehavioural outcomes in a rat model of severe spinal cord injury associated with arachnoiditis.

Austin JW, Kang CE, Baumann MD, DiDiodato L, Satkunendrarajah K, Wilson JR, Stanisz GJ, Shoichet MS, Fehlings MG.

Biomaterials. 2012 Jun;33(18):4555-64. doi: 10.1016/j.biomaterials.2012.03.022. Epub 2012 Mar 27.

PMID:
22459192
28.

Intestinal toxemia botulism in 3 adults, Ontario, Canada, 2006-2008.

Sheppard YD, Middleton D, Whitfield Y, Tyndel F, Haider S, Spiegelman J, Swartz RH, Nelder MP, Baker SL, Landry L, Maceachern R, Deamond S, Ross L, Peters G, Baird M, Rose D, Sanders G, Austin JW.

Emerg Infect Dis. 2012 Jan;18(1):1-6. doi: 10.3201/eid1801.110533.

29.

Survey of neurosurgical management of central nervous system hemorrhage in patients receiving anticoagulation therapy: current practice is highly variable and may be suboptimal.

Hawryluk GW, Furlan JC, Austin JW, Fehlings MG.

World Neurosurg. 2011 Sep-Oct;76(3-4):299-303. doi: 10.1016/j.wneu.2011.03.034.

PMID:
21986428
30.

Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells.

Youngblood B, Oestreich KJ, Ha SJ, Duraiswamy J, Akondy RS, West EE, Wei Z, Lu P, Austin JW, Riley JL, Boss JM, Ahmed R.

Immunity. 2011 Sep 23;35(3):400-12. doi: 10.1016/j.immuni.2011.06.015.

31.

Multiplex polymerase chain reaction diagnostics of bed bug (Hemiptera: Cimicidae).

Szalanski AL, Tripodi AD, Austin JW.

J Med Entomol. 2011 Jul;48(4):937-40.

PMID:
21845958
32.

Posttraumatic syringomyelia.

Fehlings MG, Austin JW.

J Neurosurg Spine. 2011 May;14(5):570-2; discussion 572. doi: 10.3171/2010.4.SPINE1047. Epub 2011 Feb 25. No abstract available.

PMID:
21388289
33.

Botulism in the North: a disease without borders.

Austin JW, Leclair D.

Clin Infect Dis. 2011 Mar 1;52(5):593-4. doi: 10.1093/cid/ciq256. No abstract available.

PMID:
21292664
34.

Management of anticoagulation following central nervous system hemorrhage in patients with high thromboembolic risk.

Hawryluk GW, Austin JW, Furlan JC, Lee JB, O'Kelly C, Fehlings MG.

J Thromb Haemost. 2010 Jul;8(7):1500-8. doi: 10.1111/j.1538-7836.2010.03882.x. Epub 2010 Apr 8.

35.

Abasic sites and strand breaks in DNA cause transcriptional mutagenesis in Escherichia coli.

Clauson CL, Oestreich KJ, Austin JW, Doetsch PW.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3657-62. doi: 10.1073/pnas.0913191107. Epub 2010 Feb 8.

36.

Systemic polyethylene glycol promotes neurological recovery and tissue sparing in rats after cervical spinal cord injury.

Baptiste DC, Austin JW, Zhao W, Nahirny A, Sugita S, Fehlings MG.

J Neuropathol Exp Neurol. 2009 Jun;68(6):661-76. doi: 10.1097/NEN.0b013e3181a72605.

PMID:
19458542
37.

Physical and genetic characterization of an outer-membrane protein (OmpM1) containing an N-terminal S-layer-like homology domain from the phylogenetically Gram-positive gut anaerobe Mitsuokella multacida.

Kalmokoff ML, Austin JW, Cyr TD, Hefford MA, Teather RM, Selinger LB.

Anaerobe. 2009 Jun;15(3):74-81. doi: 10.1016/j.anaerobe.2009.01.001. Epub 2009 Jan 20.

PMID:
19344649
38.

Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum.

Carter AT, Paul CJ, Mason DR, Twine SM, Alston MJ, Logan SM, Austin JW, Peck MW.

BMC Genomics. 2009 Mar 19;10:115. doi: 10.1186/1471-2164-10-115.

39.

Bowel loops and eyelid droops.

Spiegelman J, Cescon DW, Friedman Y, Mazza BV, Austin JW, Rachlis A, Murray BJ.

CMAJ. 2008 Oct 21;179(9):927-9. doi: 10.1503/cmaj.080651.

40.

A quantitative ELISA for bioactive anti-Nogo-A, a promising regenerative molecule for spinal cord injury repair.

Baumann MD, Austin JW, Fehlings MG, Shoichet MS.

Methods. 2009 Feb;47(2):104-8. doi: 10.1016/j.ymeth.2008.07.007. Epub 2008 Aug 12.

PMID:
18703145
41.

Flagellar glycosylation in Clostridium botulinum.

Twine SM, Paul CJ, Vinogradov E, McNally DJ, Brisson JR, Mullen JA, McMullin DR, Jarrell HC, Austin JW, Kelly JF, Logan SM.

FEBS J. 2008 Sep;275(17):4428-44. doi: 10.1111/j.1742-4658.2008.06589.x. Epub 2008 Jul 30.

42.

Molecular mechanisms of Fas-mediated cell death in oligodendrocytes.

Austin JW, Fehlings MG.

J Neurotrauma. 2008 May;25(5):411-26. doi: 10.1089/neu.2007.0436.

PMID:
18435595
43.

Mitochondrial and ribosomal internal transcribed spacer 1 diversity of Cimex lectularius (Hemiptera: Cimicidae).

Szalanski AL, Austin JW, McKern JA, Steelman CD, Gold RE.

J Med Entomol. 2008 Mar;45(2):229-36.

PMID:
18402138
44.

An outbreak of foodborne botulism in Ontario.

Loutfy MR, Austin JW, Blanchfield B, Fong IW.

Can J Infect Dis. 2003 Jul;14(4):206-9.

47.

Flagellin diversity in Clostridium botulinum groups I and II: a new strategy for strain identification.

Paul CJ, Twine SM, Tam KJ, Mullen JA, Kelly JF, Austin JW, Logan SM.

Appl Environ Microbiol. 2007 May;73(9):2963-75. Epub 2007 Mar 9.

48.

Repeated low-level exposure of the round goby (Neogobius melanostomas) to Clostridium botulinum type E neurotoxin.

Yule AM, LePage V, Austin JW, Barker IK, Moccia RD.

J Wildl Dis. 2006 Jul;42(3):494-500.

PMID:
17092879
49.

Toxicity of Clostridium botulinum type E neurotoxin to Great Lakes fish: implications for avian botulism.

Yule AM, Barker IK, Austin JW, Moccia RD.

J Wildl Dis. 2006 Jul;42(3):479-93.

PMID:
17092878
50.

Differentiation of group I and group II strains of Clostridium botulinum by focal plane array Fourier transform infrared spectroscopy.

Kirkwood J, Ghetler A, Sedman J, Leclair D, Pagotto F, Austin JW, Ismail AA.

J Food Prot. 2006 Oct;69(10):2377-83.

PMID:
17066916

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