Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 743


AAAAI Mast Cell Disorders Committee Work Group Report: Mast cell activation syndrome (MCAS) diagnosis and management.

Weiler CR, Austen KF, Akin C, Barkoff MS, Bernstein JA, Bonadonna P, Butterfield JH, Carter M, Fox CC, Maitland A, Pongdee T, Mustafa SS, Ravi A, Tobin MC, Vliagoftis H, Schwartz LB.

J Allergy Clin Immunol. 2019 Oct;144(4):883-896. doi: 10.1016/j.jaci.2019.08.023. Epub 2019 Aug 30.


Roles of cysteinyl leukotrienes and their receptors in immune cell-related functions.

Kanaoka Y, Austen KF.

Adv Immunol. 2019;142:65-84. doi: 10.1016/ Epub 2019 May 14.


Mechanical Skin Injury Promotes Food Anaphylaxis by Driving Intestinal Mast Cell Expansion.

Leyva-Castillo JM, Galand C, Kam C, Burton O, Gurish M, Musser MA, Goldsmith JD, Hait E, Nurko S, Brombacher F, Dong C, Finkelman FD, Lee RT, Ziegler S, Chiu I, Austen KF, Geha RS.

Immunity. 2019 May 21;50(5):1262-1275.e4. doi: 10.1016/j.immuni.2019.03.023. Epub 2019 Apr 23.


Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis.

Duah E, Teegala LR, Kondeti V, Adapala RK, Keshamouni VG, Kanaoka Y, Austen KF, Thodeti CK, Paruchuri S.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):199-204. doi: 10.1073/pnas.1817325115. Epub 2018 Dec 17.


Mentoring: An art and a responsibility.

Austen KF.

J Allergy Clin Immunol. 2018 Mar;141(3):880-881. doi: 10.1016/j.jaci.2018.01.004. Epub 2018 Jan 31. No abstract available.


Resolution of a human mast cell development conundrum.

Austen KF, Gurish MF.

Blood. 2017 Oct 19;130(16):1777-1778. doi: 10.1182/blood-2017-09-802173. No abstract available.


Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future.

Valent P, Akin C, Hartmann K, Nilsson G, Reiter A, Hermine O, Sotlar K, Sperr WR, Escribano L, George TI, Kluin-Nelemans HC, Ustun C, Triggiani M, Brockow K, Gotlib J, Orfao A, Schwartz LB, Broesby-Olsen S, Bindslev-Jensen C, Kovanen PT, Galli SJ, Austen KF, Arber DA, Horny HP, Arock M, Metcalfe DD.

Cancer Res. 2017 Mar 15;77(6):1261-1270. doi: 10.1158/0008-5472.CAN-16-2234. Epub 2017 Mar 2. Review.


Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s.

von Moltke J, O'Leary CE, Barrett NA, Kanaoka Y, Austen KF, Locksley RM.

J Exp Med. 2017 Jan;214(1):27-37. doi: 10.1084/jem.20161274. Epub 2016 Dec 23.


CysLT1 Receptor Is Protective against Oxidative Stress in a Model of Irritant-Induced Asthma.

McGovern T, Goldberger M, Chen M, Allard B, Hamamoto Y, Kanaoka Y, Austen KF, Powell WS, Martin JG.

J Immunol. 2016 Jul 1;197(1):266-77. doi: 10.4049/jimmunol.1501084. Epub 2016 May 25.


Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99.

Bankova LG, Lai J, Yoshimoto E, Boyce JA, Austen KF, Kanaoka Y, Barrett NA.

Proc Natl Acad Sci U S A. 2016 May 31;113(22):6242-7. doi: 10.1073/pnas.1605957113. Epub 2016 May 16.


Expression profiling of constitutive mast cells reveals a unique identity within the immune system.

Dwyer DF, Barrett NA, Austen KF; Immunological Genome Project Consortium.

Nat Immunol. 2016 Jul;17(7):878-87. doi: 10.1038/ni.3445. Epub 2016 May 2.


Licensed to Ill: IL-9 Generation in Immature Mast Cells Permits Food-Elicited Anaphylaxis.

Barrett NA, Austen KF.

Immunity. 2015 Oct 20;43(4):626-8. doi: 10.1016/j.immuni.2015.09.011.


Maturation of mast cell progenitors to mucosal mast cells during allergic pulmonary inflammation in mice.

Bankova LG, Dwyer DF, Liu AY, Austen KF, Gurish MF.

Mucosal Immunol. 2015 May;8(3):596-606. doi: 10.1038/mi.2014.91. Epub 2014 Oct 8.


B cells regulate CD4+ T cell responses to papain following B cell receptor-independent papain uptake.

Dwyer DF, Woodruff MC, Carroll MC, Austen KF, Gurish MF.

J Immunol. 2014 Jul 15;193(2):529-39. doi: 10.4049/jimmunol.1303247. Epub 2014 Jun 13.


K. Frank Austen. Boston, Mass., USA.

Austen KF.

Chem Immunol Allergy. 2014;100:340-1. doi: 10.1159/000360050. Epub 2014 May 22. No abstract available.


Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions.

Bankova LG, Lezcano C, Pejler G, Stevens RL, Murphy GF, Austen KF, Gurish MF.

J Immunol. 2014 Mar 15;192(6):2812-20. doi: 10.4049/jimmunol.1301794. Epub 2014 Feb 12.


Dectin-2 regulates the effector phase of house dust mite-elicited pulmonary inflammation independently from its role in sensitization.

Parsons MW, Li L, Wallace AM, Lee MJ, Katz HR, Fernandez JM, Saijo S, Iwakura Y, Austen KF, Kanaoka Y, Barrett NA.

J Immunol. 2014 Feb 15;192(4):1361-71. doi: 10.4049/jimmunol.1301809. Epub 2014 Jan 22.


Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand.

Kanaoka Y, Maekawa A, Austen KF.

J Biol Chem. 2013 Apr 19;288(16):10967-72. doi: 10.1074/jbc.C113.453704. Epub 2013 Mar 15.


Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis.

Bartnikas LM, Gurish MF, Burton OT, Leisten S, Janssen E, Oettgen HC, Beaupré J, Lewis CN, Austen KF, Schulte S, Hornick JL, Geha RS, Oyoshi MK.

J Allergy Clin Immunol. 2013 Feb;131(2):451-60.e1-6. doi: 10.1016/j.jaci.2012.11.032.


Mast cells recruited to mesenteric lymph nodes during helminth infection remain hypogranular and produce IL-4 and IL-6.

Liu AY, Dwyer DF, Jones TG, Bankova LG, Shen S, Katz HR, Austen KF, Gurish MF.

J Immunol. 2013 Feb 15;190(4):1758-66. doi: 10.4049/jimmunol.1202567. Epub 2013 Jan 14.


Cysteinyl leukotriene 2 receptor on dendritic cells negatively regulates ligand-dependent allergic pulmonary inflammation.

Barrett NA, Fernandez JM, Maekawa A, Xing W, Li L, Parsons MW, Austen KF, Kanaoka Y.

J Immunol. 2012 Nov 1;189(9):4556-65. doi: 10.4049/jimmunol.1201865. Epub 2012 Sep 21.


Developmental origin and functional specialization of mast cell subsets.

Gurish MF, Austen KF.

Immunity. 2012 Jul 27;37(1):25-33. doi: 10.1016/j.immuni.2012.07.003. Review.


Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis.

Oyoshi MK, He R, Kanaoka Y, ElKhal A, Kawamoto S, Lewis CN, Austen KF, Geha RS.

Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):4992-7. doi: 10.1073/pnas.1203127109. Epub 2012 Mar 13.


Mast cell deficiency, a game of kit and mouse.

Katz HR, Austen KF.

Immunity. 2011 Nov 23;35(5):668-70. doi: 10.1016/j.immuni.2011.11.004.


Cysteinyl leukotrienes impair hypoxic pulmonary vasoconstriction in endotoxemic mice.

Petersen B, Austen KF, Bloch KD, Hotta Y, Ichinose F, Kanaoka Y, Zapol WM.

Anesthesiology. 2011 Oct;115(4):804-11. doi: 10.1097/ALN.0b013e31822e94bd.


Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue.

Xing W, Austen KF, Gurish MF, Jones TG.

Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14210-5. doi: 10.1073/pnas.1111048108. Epub 2011 Aug 8.


The catalytic architecture of leukotriene C4 synthase with two arginine residues.

Saino H, Ukita Y, Ago H, Irikura D, Nisawa A, Ueno G, Yamamoto M, Kanaoka Y, Lam BK, Austen KF, Miyano M.

J Biol Chem. 2011 May 6;286(18):16392-401. doi: 10.1074/jbc.M110.150177. Epub 2011 Mar 16.


Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes.

Barrett NA, Rahman OM, Fernandez JM, Parsons MW, Xing W, Austen KF, Kanaoka Y.

J Exp Med. 2011 Mar 14;208(3):593-604. doi: 10.1084/jem.20100793. Epub 2011 Feb 28.


The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5.

Younan G, Suber F, Xing W, Shi T, Kunori Y, Abrink M, Pejler G, Schlenner SM, Rodewald HR, Moore FD Jr, Stevens RL, Adachi R, Austen KF, Gurish MF.

J Immunol. 2010 Dec 15;185(12):7681-90. doi: 10.4049/jimmunol.1002803. Epub 2010 Nov 12.


T regulatory cells control antigen-induced recruitment of mast cell progenitors to the lungs of C57BL/6 mice.

Jones TG, Finkelman FD, Austen KF, Gurish MF.

J Immunol. 2010 Aug 1;185(3):1804-11. doi: 10.4049/jimmunol.1001146. Epub 2010 Jul 2.


GPR17 regulates immune pulmonary inflammation induced by house dust mites.

Maekawa A, Xing W, Austen KF, Kanaoka Y.

J Immunol. 2010 Aug 1;185(3):1846-54. doi: 10.4049/jimmunol.1001131. Epub 2010 Jun 23. Erratum in: J Immunol. 2010 Oct 1;185(7):4506.


The role of the CCL2/CCR2 axis in mouse mast cell migration in vitro and in vivo.

Collington SJ, Hallgren J, Pease JE, Jones TG, Rollins BJ, Westwick J, Austen KF, Williams TJ, Gurish MF, Weller CL.

J Immunol. 2010 Jun 1;184(11):6114-23. doi: 10.4049/jimmunol.0904177. Epub 2010 Apr 28.


Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells.

Jones TG, Hallgren J, Humbles A, Burwell T, Finkelman FD, Alcaide P, Austen KF, Gurish MF.

J Immunol. 2009 Oct 15;183(8):5251-60. doi: 10.4049/jimmunol.0901471. Epub 2009 Sep 25.


Innate cells and T helper 2 cell immunity in airway inflammation.

Barrett NA, Austen KF.

Immunity. 2009 Sep 18;31(3):425-37. doi: 10.1016/j.immuni.2009.08.014. Review.


The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobiologic implications.

Austen KF, Maekawa A, Kanaoka Y, Boyce JA.

J Allergy Clin Immunol. 2009 Sep;124(3):406-14; quiz 415-6. doi: 10.1016/j.jaci.2009.05.046. Epub 2009 Aug 3. Review.


GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4.

Maekawa A, Balestrieri B, Austen KF, Kanaoka Y.

Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11685-90. doi: 10.1073/pnas.0905364106. Epub 2009 Jun 26.


Density functional theory study of the binding of glycine, proline, and hydroxyproline to the hydroxyapatite (0001) and (0110) surfaces.

Almora-Barrios N, Austen KF, de Leeuw NH.

Langmuir. 2009 May 5;25(9):5018-25. doi: 10.1021/la803842g.


Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells.

Barrett NA, Maekawa A, Rahman OM, Austen KF, Kanaoka Y.

J Immunol. 2009 Jan 15;182(2):1119-28.


New tools to support collaboration and virtual organizations.

Frame I, Austen KF, Calleja M, Dove MT, White TO, Wilson DJ.

Philos Trans A Math Phys Eng Sci. 2009 Mar 13;367(1890):1051-6. doi: 10.1098/rsta.2008.0193.


eScience for molecular-scale simulations and the eMinerals project.

Salje EK, Artacho E, Austen KF, Bruin RP, Calleja M, Chappell HF, Chiang GT, Dove MT, Frame I, Goodwin AL, Kleese van Dam K, Marmier A, Parker SC, Pruneda JM, Todorov IT, Trachenko K, Tyer RP, Walker AM, White TO.

Philos Trans A Math Phys Eng Sci. 2009 Mar 13;367(1890):967-85. doi: 10.1098/rsta.2008.0195.


Outbreak of adverse reactions associated with contaminated heparin.

Blossom DB, Kallen AJ, Patel PR, Elward A, Robinson L, Gao G, Langer R, Perkins KM, Jaeger JL, Kurkjian KM, Jones M, Schillie SF, Shehab N, Ketterer D, Venkataraman G, Kishimoto TK, Shriver Z, McMahon AW, Austen KF, Kozlowski S, Srinivasan A, Turabelidze G, Gould CV, Arduino MJ, Sasisekharan R.

N Engl J Med. 2008 Dec 18;359(25):2674-84. doi: 10.1056/NEJMoa0806450. Epub 2008 Dec 3. Erratum in: N Engl J Med. 2010 Mar 18;362(11):1056.


Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors.

Maekawa A, Kanaoka Y, Xing W, Austen KF.

Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16695-700. doi: 10.1073/pnas.0808993105. Epub 2008 Oct 17.


Contaminated heparin associated with adverse clinical events and activation of the contact system.

Kishimoto TK, Viswanathan K, Ganguly T, Elankumaran S, Smith S, Pelzer K, Lansing JC, Sriranganathan N, Zhao G, Galcheva-Gargova Z, Al-Hakim A, Bailey GS, Fraser B, Roy S, Rogers-Cotrone T, Buhse L, Whary M, Fox J, Nasr M, Dal Pan GJ, Shriver Z, Langer RS, Venkataraman G, Austen KF, Woodcock J, Sasisekharan R.

N Engl J Med. 2008 Jun 5;358(23):2457-67. doi: 10.1056/NEJMoa0803200. Epub 2008 Apr 23. Erratum in: N Engl J Med. 2010 Mar 18;362(11):1056.


The cysteinyl leukotrienes: where do they come from? What are they? Where are they going?

Austen KF.

Nat Immunol. 2008 Feb;9(2):113-5. doi: 10.1038/ni0208-113.


Pulmonary CXCR2 regulates VCAM-1 and antigen-induced recruitment of mast cell progenitors.

Hallgren J, Jones TG, Abonia JP, Xing W, Humbles A, Austen KF, Gurish MF.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20478-83. Epub 2007 Dec 10.


Mast cell deficiency in Kit(W-sh) mice does not impair antibody-mediated arthritis.

Zhou JS, Xing W, Friend DS, Austen KF, Katz HR.

J Exp Med. 2007 Nov 26;204(12):2797-802. Epub 2007 Nov 6.


Doing what I like.

Austen KF.

Annu Rev Immunol. 2008;26:1-28.


Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis.

Ago H, Kanaoka Y, Irikura D, Lam BK, Shimamura T, Austen KF, Miyano M.

Nature. 2007 Aug 2;448(7153):609-12. Epub 2007 Jul 15.


Additional functions for the cysteinyl leukotrienes recognized through studies of inflammatory processes in null strains.

Austen KF.

Prostaglandins Other Lipid Mediat. 2007 May;83(3):182-7. Epub 2007 Jan 17. Review.


Supplemental Content

Loading ...
Support Center