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Items: 1 to 50 of 113

1.

Bromodomain inhibitor JQ1 reversibly blocks IFN-γ production.

Gibbons HR, Mi DJ, Farley VM, Esmond T, Kaood MB, Aune TM.

Sci Rep. 2019 Jul 16;9(1):10280. doi: 10.1038/s41598-019-46516-x.

2.

Juvenile idiopathic arthritis associated with a mutation in GATA3.

Patrick AE, Wang W, Brokamp E, Graham TB, Aune TM, Duis JB.

Arthritis Res Ther. 2019 Jun 25;21(1):156. doi: 10.1186/s13075-019-1946-3.

3.

Endogenous double-stranded Alu RNA elements stimulate IFN-responses in relapsing remitting multiple sclerosis.

Heinrich MJ, Purcell CA, Pruijssers AJ, Zhao Y, Spurlock CF 3rd, Sriram S, Ogden KM, Dermody TS, Scholz MB, Crooke PS 3rd, Karijolich J, Aune TM.

J Autoimmun. 2019 Jun;100:40-51. doi: 10.1016/j.jaut.2019.02.003. Epub 2019 Feb 28.

PMID:
30826177
4.

Longitudinal changes in the expression of IL-33 and IL-33 regulated genes in relapsing remitting MS.

Sriram S, Shaginurova G, Tossberg JT, Natarajan C, Spurlock CF 3rd, Aune TM.

PLoS One. 2018 Dec 18;13(12):e0208755. doi: 10.1371/journal.pone.0208755. eCollection 2018.

5.

Biological Effects of IL-26 on T Cell-Mediated Skin Inflammation, Including Psoriasis.

Itoh T, Hatano R, Komiya E, Otsuka H, Narita Y, Aune TM, Dang NH, Matsuoka S, Naito H, Tominaga M, Takamori K, Morimoto C, Ohnuma K.

J Invest Dermatol. 2019 Apr;139(4):878-889. doi: 10.1016/j.jid.2018.09.037. Epub 2018 Nov 10.

PMID:
30423328
6.

Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells.

Gibbons HR, Shaginurova G, Kim LC, Chapman N, Spurlock CF 3rd, Aune TM.

Front Immunol. 2018 Oct 29;9:2512. doi: 10.3389/fimmu.2018.02512. eCollection 2018.

7.

Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells.

Spurlock CF 3rd, Shaginurova G, Tossberg JT, Hester JD, Chapman N, Guo Y, Crooke PS 3rd, Aune TM.

J Immunol. 2017 Jul 15;199(2):547-558. doi: 10.4049/jimmunol.1700232. Epub 2017 Jun 9.

8.

Expression of long non-coding RNAs in autoimmunity and linkage to enhancer function and autoimmune disease risk genetic variants.

Aune TM, Crooke PS 3rd, Patrick AE, Tossberg JT, Olsen NJ, Spurlock CF 3rd.

J Autoimmun. 2017 Jul;81:99-109. doi: 10.1016/j.jaut.2017.03.014. Epub 2017 Apr 15.

9.

Biogenesis and Transcriptional Regulation of Long Noncoding RNAs in the Human Immune System.

Spurlock CF 3rd, Crooke PS 3rd, Aune TM.

J Immunol. 2016 Dec 15;197(12):4509-4517. Review.

10.

Long noncoding RNAs in T lymphocytes.

Aune TM, Crooke PS 3rd, Spurlock CF 3rd.

J Leukoc Biol. 2016 Jan;99(1):31-44. doi: 10.1189/jlb.1RI0815-389R. Epub 2015 Nov 4. Review.

11.

Long non-coding RNAs in innate and adaptive immunity.

Aune TM, Spurlock CF 3rd.

Virus Res. 2016 Jan 2;212:146-60. doi: 10.1016/j.virusres.2015.07.003. Epub 2015 Jul 9. Review.

12.

Cutting Edge: Chronic NF-κB Activation in CD4+ T Cells in Rheumatoid Arthritis Is Genetically Determined by HLA Risk Alleles.

Spurlock CF 3rd, Tossberg JT, Olsen NJ, Aune TM.

J Immunol. 2015 Aug 1;195(3):791-5. doi: 10.4049/jimmunol.1500267. Epub 2015 Jun 19.

13.

Expression and functions of long noncoding RNAs during human T helper cell differentiation.

Spurlock CF 3rd, Tossberg JT, Guo Y, Collier SP, Crooke PS 3rd, Aune TM.

Nat Commun. 2015 Apr 23;6:6932. doi: 10.1038/ncomms7932.

14.

Defective structural RNA processing in relapsing-remitting multiple sclerosis.

Spurlock CF 3rd, Tossberg JT, Guo Y, Sriram S, Crooke PS 3rd, Aune TM.

Genome Biol. 2015 Mar 25;16:58. doi: 10.1186/s13059-015-0629-x.

15.

Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes.

Ohnuma K, Hatano R, Aune TM, Otsuka H, Iwata S, Dang NH, Yamada T, Morimoto C.

J Immunol. 2015 Apr 15;194(8):3697-712. doi: 10.4049/jimmunol.1402785. Epub 2015 Mar 18.

16.

Regulation of the Th1 genomic locus from Ifng through Tmevpg1 by T-bet.

Collier SP, Henderson MA, Tossberg JT, Aune TM.

J Immunol. 2014 Oct 15;193(8):3959-65. doi: 10.4049/jimmunol.1401099. Epub 2014 Sep 15.

17.

Expression of IL-33 and its epigenetic regulation in Multiple Sclerosis.

Zhang F, Tossberg JT, Spurlock CF, Yao SY, Aune TM, Sriram S.

Ann Clin Transl Neurol. 2014 May 1;1(5):307-318.

18.

Methotrexate-mediated inhibition of nuclear factor κB activation by distinct pathways in T cells and fibroblast-like synoviocytes.

Spurlock CF 3rd, Gass HM 4th, Bryant CJ, Wells BC, Olsen NJ, Aune TM.

Rheumatology (Oxford). 2015 Jan;54(1):178-87. doi: 10.1093/rheumatology/keu279. Epub 2014 Aug 12.

19.

Methotrexate inhibits NF-κB activity via long intergenic (noncoding) RNA-p21 induction.

Spurlock CF 3rd, Tossberg JT, Matlock BK, Olsen NJ, Aune TM.

Arthritis Rheumatol. 2014 Nov;66(11):2947-57. doi: 10.1002/art.38805.

20.

KLF2 is a rate-limiting transcription factor that can be targeted to enhance regulatory T-cell production.

Pabbisetty SK, Rabacal W, Maseda D, Cendron D, Collins PL, Hoek KL, Parekh VV, Aune TM, Sebzda E.

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9579-84. doi: 10.1073/pnas.1323493111. Epub 2014 Jun 16.

21.

Methotrexate induces production of IL-1 and IL-6 in the monocytic cell line U937.

Olsen NJ, Spurlock CF 3rd, Aune TM.

Arthritis Res Ther. 2014 Jan 20;16(1):R17. doi: 10.1186/ar4444.

22.

The invasive chytrid fungus of amphibians paralyzes lymphocyte responses.

Fites JS, Ramsey JP, Holden WM, Collier SP, Sutherland DM, Reinert LK, Gayek AS, Dermody TS, Aune TM, Oswald-Richter K, Rollins-Smith LA.

Science. 2013 Oct 18;342(6156):366-9. doi: 10.1126/science.1243316.

23.

Using biomarkers to predict progression from clinically isolated syndrome to multiple sclerosis.

Tossberg JT, Crooke PS, Henderson MA, Sriram S, Mrelashvili D, Vosslamber S, Verweij CL, Olsen NJ, Aune TM.

J Clin Bioinforma. 2013 Oct 3;3(1):18. doi: 10.1186/2043-9113-3-18.

24.

Epigenetic Activation and Silencing of the Gene that Encodes IFN-γ.

Aune TM, Collins PL, Collier SP, Henderson MA, Chang S.

Front Immunol. 2013 May 16;4:112. doi: 10.3389/fimmu.2013.00112. eCollection 2013.

25.

Using gene expression data to identify certain gastro-intestinal diseases.

Crooke PS, Tossberg JT, Horst SN, Tauscher JL, Henderson MA, Beaulieu DB, Schwartz DA, Olsen NJ, Aune TM.

J Clin Bioinforma. 2012 Nov 21;2(1):20. doi: 10.1186/2043-9113-2-20.

26.

Reciprocal regulation of Rag expression in thymocytes by the zinc-finger proteins, Zfp608 and Zfp609.

Reed NP, Henderson MA, Oltz EM, Aune TM.

Genes Immun. 2013 Jan;14(1):7-12. doi: 10.1038/gene.2012.47. Epub 2012 Oct 18.

27.

Cutting edge: influence of Tmevpg1, a long intergenic noncoding RNA, on the expression of Ifng by Th1 cells.

Collier SP, Collins PL, Williams CL, Boothby MR, Aune TM.

J Immunol. 2012 Sep 1;189(5):2084-8. doi: 10.4049/jimmunol.1200774. Epub 2012 Jul 30. Erratum in: J Immunol. 2014 Jan 1;192(1):533.

28.

Lineage-specific adjacent IFNG and IL26 genes share a common distal enhancer element.

Collins PL, Henderson MA, Aune TM.

Genes Immun. 2012 Sep;13(6):481-8. doi: 10.1038/gene.2012.22. Epub 2012 May 24.

29.

Diverse functions of distal regulatory elements at the IFNG locus.

Collins PL, Henderson MA, Aune TM.

J Immunol. 2012 Feb 15;188(4):1726-33. doi: 10.4049/jimmunol.1102879. Epub 2012 Jan 13.

30.

Methotrexate increases expression of cell cycle checkpoint genes via JNK activation.

Spurlock CF 3rd, Tossberg JT, Fuchs HA, Olsen NJ, Aune TM.

Arthritis Rheum. 2012 Jun;64(6):1780-9. doi: 10.1002/art.34342. Epub 2011 Dec 19.

31.

Gene-expression signatures: biomarkers toward diagnosing multiple sclerosis.

Tossberg JT, Crooke PS, Henderson MA, Sriram S, Mrelashvili D, Chitnis S, Polman C, Vosslamber S, Verweij CL, Olsen NJ, Aune TM.

Genes Immun. 2012 Feb;13(2):146-54. doi: 10.1038/gene.2011.66. Epub 2011 Sep 22.

32.

Increased sensitivity to apoptosis induced by methotrexate is mediated by JNK.

Spurlock CF 3rd, Aune ZT, Tossberg JT, Collins PL, Aune JP, Huston JW 3rd, Crooke PS, Olsen NJ, Aune TM.

Arthritis Rheum. 2011 Sep;63(9):2606-16. doi: 10.1002/art.30457.

33.
34.

Peripheral blood gene expression profiles in metabolic syndrome, coronary artery disease and type 2 diabetes.

Grayson BL, Wang L, Aune TM.

Genes Immun. 2011 Jul;12(5):341-51. doi: 10.1038/gene.2011.13. Epub 2011 Mar 3.

35.

An efficient hierarchical generalized linear mixed model for pathway analysis of genome-wide association studies.

Wang L, Jia P, Wolfinger RD, Chen X, Grayson BL, Aune TM, Zhao Z.

Bioinformatics. 2011 Mar 1;27(5):686-92. doi: 10.1093/bioinformatics/btq728. Epub 2011 Jan 25.

36.

Genome-wide analysis of copy number variation in type 1 diabetes.

Grayson BL, Smith ME, Thomas JW, Wang L, Dexheimer P, Jeffrey J, Fain PR, Nanduri P, Eisenbarth GS, Aune TM.

PLoS One. 2010 Nov 15;5(11):e15393. doi: 10.1371/journal.pone.0015393.

37.

Follicular B cell trafficking within the spleen actively restricts humoral immune responses.

Hoek KL, Gordy LE, Collins PL, Parekh VV, Aune TM, Joyce S, Thomas JW, Van Kaer L, Sebzda E.

Immunity. 2010 Aug 27;33(2):254-65. doi: 10.1016/j.immuni.2010.07.016. Epub 2010 Aug 5.

38.

Distal regions of the human IFNG locus direct cell type-specific expression.

Collins PL, Chang S, Henderson M, Soutto M, Davis GM, McLoed AG, Townsend MJ, Glimcher LH, Mortlock DP, Aune TM.

J Immunol. 2010 Aug 1;185(3):1492-501. doi: 10.4049/jimmunol.1000124. Epub 2010 Jun 23.

39.

Keeping one's option open.

Collins PL, Aune TM.

Immunity. 2010 May 28;32(5):581-3. doi: 10.1016/j.immuni.2010.05.008.

40.

Change in mRNA Expression after Atenolol, a Beta-adrenergic Receptor Antagonist and Association with Pharmacological Response.

Kohli U, Grayson BL, Aune TM, Ghimire LV, Kurnik D, Stein CM.

Arch Drug Inf. 2009 Sep;2(3):41-50.

41.

Epigenetics and T helper 1 differentiation.

Aune TM, Collins PL, Chang S.

Immunology. 2009 Mar;126(3):299-305. doi: 10.1111/j.1365-2567.2008.03026.x. Epub 2008 Dec 18. Review.

42.

Prediction of disease severity in patients with early rheumatoid arthritis by gene expression profiling.

Liu Z, Sokka T, Maas K, Olsen NJ, Aune TM.

Hum Genomics Proteomics. 2009 Apr 27;2009. pii: 484351. doi: 10.4061/2009/484351.

43.
44.
45.

Identification of molecular biomarkers for multiple sclerosis.

Fossey SC, Vnencak-Jones CL, Olsen NJ, Sriram S, Garrison G, Deng X, Crooke PS 3rd, Aune TM.

J Mol Diagn. 2007 Apr;9(2):197-204.

46.

Selective matrix attachment regions in T helper cell subsets support loop conformation in the Ifng gene.

Eivazova ER, Vassetzky YS, Aune TM.

Genes Immun. 2007 Jan;8(1):35-43. Epub 2006 Nov 9.

PMID:
17093503
47.

Control of thymocyte development and recombination-activating gene expression by the zinc finger protein Zfp608.

Zhang F, Thomas LR, Oltz EM, Aune TM.

Nat Immunol. 2006 Dec;7(12):1309-16. Epub 2006 Oct 22.

PMID:
17057722
48.

Deregulated stress system in non-obese diabetic lymphocyte.

Liu Z, Aune TM.

Genes Immun. 2006 Jul;7(5):352-8. Epub 2006 May 11.

PMID:
16691184
49.

Highly conserved gene expression profiles in humans with allergic rhinitis altered by immunotherapy.

Liu Z, Yelverton RW, Kraft B, Tanner SB, Olsen NJ, Aune TM.

Clin Exp Allergy. 2005 Dec;35(12):1581-90.

PMID:
16393324
50.

Identification of gene expression signatures in autoimmune disease without the influence of familial resemblance.

Liu Z, Maas K, Aune TM.

Hum Mol Genet. 2006 Feb 1;15(3):501-9. Epub 2005 Dec 21. Erratum in: Hum Mol Genet. 2006 Oct 1;15(19):2973.

PMID:
16371420

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