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Development and Characterization of a Genetic Mouse Model of KRAS Mutated Colorectal Cancer.

Maitra R, Thavornwatanayong T, Venkatesh MK, Chandy C, Vachss D, Augustine T, Guzik H, Koba W, Liu Q, Goel S.

Int J Mol Sci. 2019 Nov 13;20(22). pii: E5677. doi: 10.3390/ijms20225677.


Distribution and risk assessment of trace metals in multifarious matrices of Vembanad Lake system, Peninsular India.

ShyleshChandran MS, Ramasamy EV, Mohan M, N SS, Jayasooryan KK, Augustine T, Mohan K.

Mar Pollut Bull. 2019 Aug;145:490-498. doi: 10.1016/j.marpolbul.2019.06.034. Epub 2019 Jun 25.


Excision repair cross-complementing group-1 (ERCC1) induction kinetics and polymorphism are markers of inferior outcome in patients with colorectal cancer treated with oxaliplatin.

Rao D, Mallick AB, Augustine T, Daroqui C, Jiffry J, Merla A, Chaudhary I, Seetharam R, Sood A, Gajavelli S, Aparo S, Rajdev L, Kaubisch A, Chuy J, Negassa A, Mariadason JM, Maitra R, Goel S.

Oncotarget. 2019 Sep 17;10(53):5510-5522. doi: 10.18632/oncotarget.27140. eCollection 2019 Sep 17.


Monthly variance in UK renal transplantation activity: a national retrospective cohort study.

Lowe M, Maidstone R, Poulton K, Worthington J, Durrington HJ, Ray DW, van Dellen D, Asderakis A, Blaikley J, Augustine T.

BMJ Open. 2019 Sep 17;9(9):e028786. doi: 10.1136/bmjopen-2018-028786.


Living donor kidney transplantation: often a missed opportunity.

Sharma V, Summers A, Picton M, Ainsworth J, Van Dellen D, Jones R, Augustine T.

Br J Gen Pract. 2019 Aug 29;69(686):428-429. doi: 10.3399/bjgp19X705173. Print 2019 Sep. No abstract available.


Novel protective and risk loci in hip dysplasia in German Shepherds.

Mikkola LI, Holopainen S, Lappalainen AK, Pessa-Morikawa T, Augustine TJP, Arumilli M, Hytönen MK, Hakosalo O, Lohi H, Iivanainen A.

PLoS Genet. 2019 Jul 19;15(7):e1008197. doi: 10.1371/journal.pgen.1008197. eCollection 2019 Jul.


Single stage hand assisted laparoscopic and trans thoracic excision of multifocal paraaortic and cardiac paragangliomas.

Ong KJY, Shaw A, Wadsworth R, Ball S, Hasan R, Augustine T.

J Surg Case Rep. 2019 Jun 20;2019(6):rjz169. doi: 10.1093/jscr/rjz169. eCollection 2019 Jun.


Early nerve fibre regeneration in individuals with type 1 diabetes after simultaneous pancreas and kidney transplantation.

Azmi S, Jeziorska M, Ferdousi M, Petropoulos IN, Ponirakis G, Marshall A, Alam U, Asghar O, Atkinson A, Jones W, Boulton AJM, Brines M, Augustine T, Malik RA.

Diabetologia. 2019 Aug;62(8):1478-1487. doi: 10.1007/s00125-019-4897-y. Epub 2019 Jun 7.


Insulin therapy in organ donation and transplantation.

Shapey IM, Summers A, Yiannoullou P, Bannard-Smith J, Augustine T, Rutter MK, van Dellen D.

Diabetes Obes Metab. 2019 Jul;21(7):1521-1528. doi: 10.1111/dom.13728. Epub 2019 Apr 14. Review.


Unusual Cause of Upper Gastrointestinal Bleeding in Cirrhosis.

Augustine T, Perisetti A, Tharian B.

Clin Gastroenterol Hepatol. 2019 Mar 19. pii: S1542-3565(19)30290-3. doi: 10.1016/j.cgh.2019.03.026. [Epub ahead of print] No abstract available.


Breast cancer cell-induced platelet activation is compounded by tamoxifen and anastrozole in vitro.

Pather K, Dix-Peek T, Duarte R, Chetty N, Augustine TN.

Thromb Res. 2019 May;177:51-58. doi: 10.1016/j.thromres.2019.02.027. Epub 2019 Feb 23.


Major Adverse Cardiovascular Events Following Simultaneous Pancreas and Kidney Transplantation in the United Kingdom.

Yiannoullou P, Summers A, Goh SC, Fullwood C, Khambalia H, Moinuddin Z, Shapey IM, Naish J, Miller C, Augustine T, Rutter MK, van Dellen D.

Diabetes Care. 2019 Apr;42(4):665-673. doi: 10.2337/dc18-2111. Epub 2019 Feb 14.


Immunotherapeutic advances in gastrointestinal malignancies.

Rao D, Parakrama R, Augustine T, Liu Q, Goel S, Maitra R.

NPJ Precis Oncol. 2019 Feb 5;3:4. doi: 10.1038/s41698-018-0076-8. eCollection 2019. Review.


A single-center experience of post-transplant lymphomas involving the central nervous system with a review of current literature.

Velvet AJJ, Bhutani S, Papachristos S, Dwivedi R, Picton M, Augustine T, Morton M.

Oncotarget. 2019 Jan 11;10(4):437-448. doi: 10.18632/oncotarget.26522. eCollection 2019 Jan 11.


Systematic review to assess the possibility of return of cerebral and cardiac activity after normothermic regional perfusion for donors after circulatory death.

Shapey IM, Summers A, Augustine T, van Dellen D.

Br J Surg. 2019 Feb;106(3):174-180. doi: 10.1002/bjs.11046. Epub 2019 Jan 22.


Sensitization of colorectal cancer to irinotecan therapy by PARP inhibitor rucaparib.

Augustine T, Maitra R, Zhang J, Nayak J, Goel S.

Invest New Drugs. 2019 Oct;37(5):948-960. doi: 10.1007/s10637-018-00717-9. Epub 2019 Jan 5.


Laparoscopic hand-assisted adrenalectomy for tumours larger than 5 cm.

Buxton J, Vun SH, van Dellen D, Wadsworth R, Augustine T.

Clin Endocrinol (Oxf). 2019 Jan;90(1):74-78. doi: 10.1111/cen.13883. Epub 2018 Nov 15.


Should End-of-Life Preferences Be Discussed Routinely before High-Risk Surgery?

Doherty DT, Shapey IM, Moinuddin Z, Birtles L, Summers A, Ahamed A, van Dellen D, Augustine T.

J Palliat Med. 2018 Oct 4. doi: 10.1089/jpm.2018.0048. [Epub ahead of print]


Encapsulating peritoneal sclerosis following hyperthermic intraperitoneal chemotherapy.

Mangan C, Moinuddin Z, Summers A, de Reuver P, van Dellen D, Augustine T.

ANZ J Surg. 2019 Oct;89(10):E468-E469. doi: 10.1111/ans.14770. Epub 2018 Sep 2. No abstract available.


Simultaneous en-bloc pancreas and kidney transplantation from a small pediatric donor after circulatory death.

Dobbs S, Shapey IM, Summers A, Moinuddin Z, van Dellen D, Augustine T.

Am J Transplant. 2019 Mar;19(3):929-932. doi: 10.1111/ajt.15044. Epub 2018 Aug 27.


Priority areas for cannabis and cannabinoid product research in South Africa.

Augustine TN, Cairns CJ, Chetty S, Dannatt LG, Gravett N, Grey G, Grobler G, Jafta Z, Kamerman P, Lopes J, Matsabisa MG, Mugabo P, Mulder M, Parry C, Rataemane S, Siegfried N, Steenkamp V, Thomas E, Van Zyl-Smit R.

Afr J Prim Health Care Fam Med. 2018 Jun 21;10(1):e1-e3. doi: 10.4102/phcfm.v10i1.1711.


When politics meets science: What impact might Brexit have on organ donation and transplantation in the United Kingdom?

Shapey IM, Summers AM, Simkin IJ, Augustine T, van Dellen D.

Clin Transplant. 2018 Aug;32(8):e13299. doi: 10.1111/ctr.13299. Epub 2018 Jun 21.


A case of benign osteogenic tumour in Homo naledi: Evidence for peripheral osteoma in the U.W. 101-1142 mandible.

Odes EJ, Delezene LK, Randolph-Quinney PS, Smilg JS, Augustine TN, Jakata K, Berger LR.

Int J Paleopathol. 2018 Jun;21:47-55. doi: 10.1016/j.ijpp.2017.05.003. Epub 2017 May 20.


Rapid on-site evaluation facilitated the diagnosis of a rare case of Talaromyces marneffei infection.

Ma W, Thiryayi SA, Holbrook M, Shelton D, Narine N, Sweeney LC, Augustine T, Bailey S, Al-Najjar H, Rana DN.

Cytopathology. 2018 Oct;29(5):497-499. doi: 10.1111/cyt.12563. Epub 2018 Jun 12. No abstract available.


Organ donation among ethnic minorities: how UK primary care can help promote it.

Pradeep A, Siddiky A, Ormandy P, Augustine T.

Br J Gen Pract. 2018 Mar;68(668):134-135. doi: 10.3399/bjgp18X695093. No abstract available.


Links between a biomarker profile, cold ischaemic time and clinical outcome following simultaneous pancreas and kidney transplantation.

Khambalia HA, Alexander MY, Nirmalan M, Weston R, Pemberton P, Moinuddin Z, Summers A, van Dellen D, Augustine T.

Cytokine. 2018 May;105:8-16. doi: 10.1016/j.cyto.2018.01.006. Epub 2018 Feb 8.


Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study.

Hernandez-Fuentes MP, Franklin C, Rebollo-Mesa I, Mollon J, Delaney F, Perucha E, Stapleton C, Borrows R, Byrne C, Cavalleri G, Clarke B, Clatworthy M, Feehally J, Fuggle S, Gagliano SA, Griffin S, Hammad A, Higgins R, Jardine A, Keogan M, Leach T, MacPhee I, Mark PB, Marsh J, Maxwell P, McKane W, McLean A, Newstead C, Augustine T, Phelan P, Powis S, Rowe P, Sheerin N, Solomon E, Stephens H, Thuraisingham R, Trembath R, Topham P, Vaughan R, Sacks SH, Conlon P, Opelz G, Soranzo N, Weale ME, Lord GM; United Kingdom and Ireland Renal Transplant Consortium (UKIRTC) and the Wellcome Trust Case Control Consortium (WTCCC)-3.

Am J Transplant. 2018 Jun;18(6):1370-1379. doi: 10.1111/ajt.14594. Epub 2018 Feb 1.


In Vivo Measurement of Surface Pressures and Retraction Distances Applied on Abdominal Organs During Surgery.

Shah D, Alderson A, Corden J, Satyadas T, Augustine T.

Surg Innov. 2018 Feb;25(1):50-56. doi: 10.1177/1553350617745952. Epub 2017 Dec 15.


Obesity and listing for renal transplantation: weighing the evidence for a growing problem.

Hossain M, Woywodt A, Augustine T, Sharma V.

Clin Kidney J. 2017 Oct;10(5):703-708. doi: 10.1093/ckj/sfx022. Epub 2017 Apr 22.


Pancreas transplantation: the donor's side of the story.

Shapey IM, Summers A, Augustine T, Rutter MK, van Dellen D.

BMJ. 2017 Aug 17;358:j3784. doi: 10.1136/bmj.j3784. No abstract available.


Telomere length regulation through epidermal growth factor receptor signaling in cancer.

Augustine T, Maitra R, Goel S.

Genes Cancer. 2017 May;8(5-6):550-558. doi: 10.18632/genesandcancer.140. Review.


Toll like receptor 3 as an immunotherapeutic target for KRAS mutated colorectal cancer.

Maitra R, Augustine T, Dayan Y, Chandy C, Coffey M, Goel S.

Oncotarget. 2017 May 23;8(21):35138-35153. doi: 10.18632/oncotarget.16812.


Cyclin F/FBXO1 Interacts with HIV-1 Viral Infectivity Factor (Vif) and Restricts Progeny Virion Infectivity by Ubiquitination and Proteasomal Degradation of Vif Protein through SCFcyclin F E3 Ligase Machinery.

Augustine T, Chaudhary P, Gupta K, Islam S, Ghosh P, Santra MK, Mitra D.

J Biol Chem. 2017 Mar 31;292(13):5349-5363. doi: 10.1074/jbc.M116.765842. Epub 2017 Feb 9.


Renal Allograft Failure After Ipilimumab Therapy for Metastatic Melanoma: A Case Report and Review of the Literature.

Jose A, Yiannoullou P, Bhutani S, Denley H, Morton M, Picton M, Summers A, van Dellen D, Augustine T.

Transplant Proc. 2016 Nov;48(9):3137-3141. doi: 10.1016/j.transproceed.2016.07.019. Review.


Kidney Transplant Recipients Requiring Critical Care Admission Within One Year of Transplant.

Okidi OO, Van Dellen D, Sobajo C, Summers A, Greer JR, Augustine T.

Exp Clin Transplant. 2017 Feb;15(1):40-46. doi: 10.6002/ect.2015.0356. Epub 2016 Dec 2.


Transperitoneal Enucleation of a Kidney Transplant Allograft Renal Cell Carcinoma.

Sarantitis I, Pararajasingam R, Forgacs B, Denley H, Wood G, Augustine T.

Exp Clin Transplant. 2018 Oct;16(5):614-616. doi: 10.6002/ect.2016.0037. Epub 2016 Nov 18.


Ultrastructural investigation of the time-dependent relationship between breast cancer cells and thrombosis induction.

van der Spuy WJ, Augustine TN.

Micron. 2016 Nov;90:59-63. doi: 10.1016/j.micron.2016.08.006. Epub 2016 Aug 27.


An ethical dilemma: malignant melanoma in a 51-year-old patient awaiting simultaneous kidney and pancreas transplantation for type 1 diabetes.

Kirby LC, Banerjee A, Augustine T, Douglas JF.

Br J Dermatol. 2016 Jul;175(1):172-4. doi: 10.1111/bjd.14554.


Circulating Cell-Free Unmethylated DNA as a Marker of Graft Dysfunction in Pancreas Transplantation.

Shapey IM, Summers AM, Augustine T, Rutter MK, van Dellen D.

Am J Transplant. 2016 Oct;16(10):3064-3065. doi: 10.1111/ajt.13949. Epub 2016 Jul 28. No abstract available.


Thrombin-Mediated Platelet Activation of Lysed Whole Blood and Platelet-Rich Plasma: A Comparison Between Platelet Activation Markers and Ultrastructural Alterations.

Augustine TN, van der Spuy WJ, Kaberry LL, Shayi M.

Microsc Microanal. 2016 Jun;22(3):630-9. doi: 10.1017/S1431927616000854.


HSP70 binding protein 1 (HspBP1) suppresses HIV-1 replication by inhibiting NF-κB mediated activation of viral gene expression.

Chaudhary P, Khan SZ, Rawat P, Augustine T, Raynes DA, Guerriero V, Mitra D.

Nucleic Acids Res. 2016 Feb 29;44(4):1613-29. doi: 10.1093/nar/gkv1151. Epub 2015 Nov 3.


Incidence and Histologic Features of Transplant Graft Pancreatitis: A Single Center Experience.

van Dellen D, Summers A, Trevelyan S, Tavakoli A, Augustine T, Pararajasingam R.

Exp Clin Transplant. 2015 Oct;13(5):449-52.


Utilization of organs from donors after circulatory death for vascularized pancreas and islet of Langerhans transplantation: recommendations from an expert group.

Berney T, Boffa C, Augustine T, Badet L, de Koning E, Pratschke J, Socci C, Friend P.

Transpl Int. 2016 Jul;29(7):798-806. doi: 10.1111/tri.12681. Epub 2015 Sep 24. Review.


A prospective cohort study of risk prediction in simultaneous pancreas and kidney transplantation.

Khambalia HA, Moinuddin Z, Summers AM, Tavakoli A, Pararajasingam R, Campbell T, Dhanda R, Forgacs B, Augustine T, van Dellen D.

Ann R Coll Surg Engl. 2015 Sep;97(6):445-50. doi: 10.1308/rcsann.2015.0001. Epub 2015 Aug 14.


Establishment of a heterotypic 3D culture system to evaluate the interaction of TREG lymphocytes and NK cells with breast cancer.

Augustine TN, Dix-Peek T, Duarte R, Candy GP.

J Immunol Methods. 2015 Nov;426:1-13. doi: 10.1016/j.jim.2015.07.003. Epub 2015 Jul 26.


Encapsulating peritoneal sclerosis: presentation without preceding symptoms.

Yiannoullou P, Kanesalingam K, van Dellen D, Augustine T.

Saudi J Kidney Dis Transpl. 2015 Mar;26(2):329-34.


Encapsulating peritoneal sclerosis-a rare but devastating peritoneal disease.

Moinuddin Z, Summers A, Van Dellen D, Augustine T, Herrick SE.

Front Physiol. 2015 Jan 5;5:470. doi: 10.3389/fphys.2014.00470. eCollection 2014. Review.


Telomere length is a novel predictive biomarker of sensitivity to anti-EGFR therapy in metastatic colorectal cancer.

Augustine TA, Baig M, Sood A, Budagov T, Atzmon G, Mariadason JM, Aparo S, Maitra R, Goel S.

Br J Cancer. 2015 Jan 20;112(2):313-8. doi: 10.1038/bjc.2014.561. Epub 2014 Nov 20.


Successful management of a ruptured mycotic pseudoaneurysm following pancreas transplantation using bovine pericardial patch: a case report.

Yiannoullou P, van Dellen D, Khambalia H, Forgacs B, Tavakoli A, Murray D, Augustine T.

Transplant Proc. 2014 Jul-Aug;46(6):2023-5. doi: 10.1016/j.transproceed.2014.06.051.


Oncolytic reovirus preferentially induces apoptosis in KRAS mutant colorectal cancer cells, and synergizes with irinotecan.

Maitra R, Seetharam R, Tesfa L, Augustine TA, Klampfer L, Coffey MC, Mariadason JM, Goel S.

Oncotarget. 2014 May 15;5(9):2807-19.

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