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Items: 42

1.

Therapeutic genome editing of triple-negative breast tumors using a noncationic and deformable nanolipogel.

Guo P, Yang J, Huang J, Auguste DT, Moses MA.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18295-18303. doi: 10.1073/pnas.1904697116. Epub 2019 Aug 26.

PMID:
31451668
2.

The effect of heterobifunctional crosslinkers on HEMA hydrogel modulus and toughness.

Boazak EM, Greene VK Jr, Auguste DT.

PLoS One. 2019 May 9;14(5):e0215895. doi: 10.1371/journal.pone.0215895. eCollection 2019.

3.

Dual complementary liposomes inhibit triple-negative breast tumor progression and metastasis.

Guo P, Yang J, Liu D, Huang L, Fell G, Huang J, Moses MA, Auguste DT.

Sci Adv. 2019 Mar 20;5(3):eaav5010. doi: 10.1126/sciadv.aav5010. eCollection 2019 Mar.

4.

Targeted Lipid Nanoemulsions Encapsulating Epigenetic Drugs Exhibit Selective Cytotoxicity on CDH1-/FOXM1+ Triple Negative Breast Cancer Cells.

Kim B, Pena CD, Auguste DT.

Mol Pharm. 2019 May 6;16(5):1813-1826. doi: 10.1021/acs.molpharmaceut.8b01065. Epub 2019 Mar 29.

PMID:
30883132
5.

Using Atomic Force Microscopy to Predict Tumor Specificity of ICAM1 Antibody-Directed Nanomedicines.

Guo P, Wang B, Liu D, Yang J, Subramanyam K, McCarthy CR, Hebert J, Moses MA, Auguste DT.

Nano Lett. 2018 Apr 11;18(4):2254-2262. doi: 10.1021/acs.nanolett.7b04801. Epub 2018 Mar 12.

PMID:
29505261
6.

Nanoparticle elasticity directs tumor uptake.

Guo P, Liu D, Subramanyam K, Wang B, Yang J, Huang J, Auguste DT, Moses MA.

Nat Commun. 2018 Jan 9;9(1):130. doi: 10.1038/s41467-017-02588-9.

7.

Incorporating gold nanoclusters and target-directed liposomes as a synergistic amplified colorimetric sensor for HER2-positive breast cancer cell detection.

Tao Y, Li M, Kim B, Auguste DT.

Theranostics. 2017 Feb 8;7(4):899-911. doi: 10.7150/thno.17927. eCollection 2017.

8.

A quantitative method for screening and identifying molecular targets for nanomedicine.

Guo P, Yang J, Bielenberg DR, Dillon D, Zurakowski D, Moses MA, Auguste DT.

J Control Release. 2017 Oct 10;263:57-67. doi: 10.1016/j.jconrel.2017.03.030. Epub 2017 Mar 22.

9.

Pattern-based sensing of triple negative breast cancer cells with dual-ligand cofunctionalized gold nanoclusters.

Tao Y, Li M, Auguste DT.

Biomaterials. 2017 Feb;116:21-33. doi: 10.1016/j.biomaterials.2016.11.050. Epub 2016 Nov 25.

10.

RGD-Targeted Liposome Binding and Uptake on Breast Cancer Cells Is Dependent on Elastin Linker Secondary Structure.

Veneti E, Tu RS, Auguste DT.

Bioconjug Chem. 2016 Aug 17;27(8):1813-21. doi: 10.1021/acs.bioconjchem.6b00205. Epub 2016 Aug 8.

PMID:
27463763
11.

Array-based identification of triple-negative breast cancer cells using fluorescent nanodot-graphene oxide complexes.

Tao Y, Auguste DT.

Biosens Bioelectron. 2016 Jul 15;81:431-437. doi: 10.1016/j.bios.2016.03.033. Epub 2016 Mar 15.

PMID:
27003608
12.

Patterned, tubular scaffolds mimic longitudinal and radial mechanics of the neonatal trachea.

Mansfield EG, Greene VK Jr, Auguste DT.

Acta Biomater. 2016 Mar;33:176-82. doi: 10.1016/j.actbio.2016.01.034. Epub 2016 Jan 25.

PMID:
26821338
13.

ICAM-1-Targeted, Lcn2 siRNA-Encapsulating Liposomes are Potent Anti-angiogenic Agents for Triple Negative Breast Cancer.

Guo P, Yang J, Jia D, Moses MA, Auguste DT.

Theranostics. 2016 Jan 1;6(1):1-13. doi: 10.7150/thno.12167. eCollection 2016.

14.

Cancer targeted therapeutics: From molecules to drug delivery vehicles.

Liu D, Auguste DT.

J Control Release. 2015 Dec 10;219:632-643. doi: 10.1016/j.jconrel.2015.08.041. Epub 2015 Sep 2.

15.

siRNA Delivery Impedes the Temporal Expression of Cytokine-Activated VCAM1 on Endothelial Cells.

Ho TT, You JO, Auguste DT.

Ann Biomed Eng. 2016 Apr;44(4):895-902. doi: 10.1007/s10439-015-1364-x. Epub 2015 Jun 23.

PMID:
26101035
16.

pH-responsive scaffolds generate a pro-healing response.

You JO, Rafat M, Almeda D, Maldonado N, Guo P, Nabzdyk CS, Chun M, LoGerfo FW, Hutchinson JW, Pradhan-Nabzdyk LK, Auguste DT.

Biomaterials. 2015 Jul;57:22-32. doi: 10.1016/j.biomaterials.2015.04.011. Epub 2015 Apr 21.

PMID:
25956194
17.

Mapping the CXCR4 receptor on breast cancer cells.

Wang B, Guo P, Auguste DT.

Biomaterials. 2015 Jul;57:161-8. doi: 10.1016/j.biomaterials.2015.04.023. Epub 2015 Apr 28.

PMID:
25916504
18.

Minimizing antibody surface density on liposomes while sustaining cytokine-activated EC targeting.

Almeda D, Wang B, Auguste DT.

Biomaterials. 2015 Feb;41:37-44. doi: 10.1016/j.biomaterials.2014.11.024. Epub 2014 Dec 2.

PMID:
25522963
19.

ICAM-1 as a molecular target for triple negative breast cancer.

Guo P, Huang J, Wang L, Jia D, Yang J, Dillon DA, Zurakowski D, Mao H, Moses MA, Auguste DT.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14710-5. doi: 10.1073/pnas.1408556111. Epub 2014 Sep 29.

20.

Inhibiting metastatic breast cancer cell migration via the synergy of targeted, pH-triggered siRNA delivery and chemokine axis blockade.

Guo P, You JO, Yang J, Jia D, Moses MA, Auguste DT.

Mol Pharm. 2014 Mar 3;11(3):755-65. doi: 10.1021/mp4004699. Epub 2014 Feb 12.

21.

A drug-delivery vehicle combining the targeting and thermal ablation of HER2+ breast-cancer cells with triggered drug release.

You JO, Guo P, Auguste DT.

Angew Chem Int Ed Engl. 2013 Apr 8;52(15):4141-6. doi: 10.1002/anie.201209804. Epub 2013 Mar 11. No abstract available.

22.

Using breast cancer cell CXCR4 surface expression to predict liposome binding and cytotoxicity.

Guo P, You JO, Yang J, Moses MA, Auguste DT.

Biomaterials. 2012 Nov;33(32):8104-10. doi: 10.1016/j.biomaterials.2012.07.043. Epub 2012 Aug 9.

23.

Synergistic effects of hypoxia and extracellular matrix cues in cardiomyogenesis.

Horton RE, Auguste DT.

Biomaterials. 2012 Sep;33(27):6313-9. doi: 10.1016/j.biomaterials.2012.05.063. Epub 2012 Jun 18.

PMID:
22717366
24.

Engineered endothelial cell adhesion via VCAM1 and E-selectin antibody-presenting alginate hydrogels.

Rafat M, Rotenstein LS, Hu JL, Auguste DT.

Acta Biomater. 2012 Jul;8(7):2697-703. doi: 10.1016/j.actbio.2012.04.010. Epub 2012 Apr 10.

PMID:
22504076
25.

Dual functionalized PVA hydrogels that adhere endothelial cells synergistically.

Rafat M, Rotenstein LS, You JO, Auguste DT.

Biomaterials. 2012 May;33(15):3880-6. doi: 10.1016/j.biomaterials.2012.02.017. Epub 2012 Feb 24.

PMID:
22364701
26.

Complementary targeting of liposomes to IL-1α and TNF-α activated endothelial cells via the transient expression of VCAM1 and E-selectin.

Gunawan RC, Almeda D, Auguste DT.

Biomaterials. 2011 Dec;32(36):9848-53. doi: 10.1016/j.biomaterials.2011.08.093. Epub 2011 Sep 22.

PMID:
21944721
27.

Cross-linked, heterogeneous colloidosomes exhibit pH-induced morphogenesis.

You JO, Rafat M, Auguste DT.

Langmuir. 2011 Sep 20;27(18):11282-6. doi: 10.1021/la202430m. Epub 2011 Aug 18.

PMID:
21823661
28.

Nanoengineering the heart: conductive scaffolds enhance connexin 43 expression.

You JO, Rafat M, Ye GJ, Auguste DT.

Nano Lett. 2011 Sep 14;11(9):3643-8. doi: 10.1021/nl201514a. Epub 2011 Aug 3.

PMID:
21800912
29.

Bioresponsive matrices in drug delivery.

You JO, Almeda D, Ye GJ, Auguste DT.

J Biol Eng. 2010 Nov 29;4:15. doi: 10.1186/1754-1611-4-15.

30.

Immunoliposomes that target endothelium in vitro are dependent on lipid raft formation.

Gunawan RC, Auguste DT.

Mol Pharm. 2010 Oct 4;7(5):1569-75. doi: 10.1021/mp9003095. Epub 2010 Aug 17.

PMID:
20666515
31.

The effect of swelling and cationic character on gene transfection by pH-sensitive nanocarriers.

You JO, Auguste DT.

Biomaterials. 2010 Sep;31(26):6859-66. doi: 10.1016/j.biomaterials.2010.04.048. Epub 2010 May 20.

PMID:
20493524
32.

Conductive, physiologically responsive hydrogels.

You JO, Auguste DT.

Langmuir. 2010 Apr 6;26(7):4607-12. doi: 10.1021/la100294p.

PMID:
20199077
33.

The role of antibody synergy and membrane fluidity in the vascular targeting of immunoliposomes.

Gunawan RC, Auguste DT.

Biomaterials. 2010 Feb;31(5):900-7. doi: 10.1016/j.biomaterials.2009.09.107. Epub 2009 Oct 30.

PMID:
19879646
34.

Nanocarrier cross-linking density and pH sensitivity regulate intracellular gene transfer.

You JO, Auguste DT.

Nano Lett. 2009 Dec;9(12):4467-73. doi: 10.1021/nl902789s.

PMID:
19842673
35.

Fabrication of reversibly adhesive fluidic devices using magnetism.

Rafat M, Raad DR, Rowat AC, Auguste DT.

Lab Chip. 2009 Oct 21;9(20):3016-9. doi: 10.1039/b907957b. Epub 2009 Jul 22.

PMID:
19789760
36.

Engineering microenvironments for embryonic stem cell differentiation to cardiomyocytes.

Horton RE, Millman JR, Colton CK, Auguste DT.

Regen Med. 2009 Sep;4(5):721-32. doi: 10.2217/rme.09.48. Review.

PMID:
19761397
37.

Embryoid body morphology influences diffusive transport of inductive biochemicals: a strategy for stem cell differentiation.

Sachlos E, Auguste DT.

Biomaterials. 2008 Dec;29(34):4471-80. doi: 10.1016/j.biomaterials.2008.08.012. Epub 2008 Sep 14.

PMID:
18793799
38.

Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes.

Auguste DT, Furman K, Wong A, Fuller J, Armes SP, Deming TJ, Langer R.

J Control Release. 2008 Sep 24;130(3):266-74. doi: 10.1016/j.jconrel.2008.06.004. Epub 2008 Jun 12.

39.

Surface rheology of hydrophobically modified PEG polymers associating with a phospholipid monolayer at the air-water interface.

Auguste DT, Kirkwood J, Kohn J, Fuller GG, Prud'homme RK.

Langmuir. 2008 Apr 15;24(8):4056-64. doi: 10.1021/la703079p. Epub 2008 Mar 5.

PMID:
18318552
40.

Feedback-regulated paclitaxel delivery based on poly(N,N-dimethylaminoethyl methacrylate-co-2-hydroxyethyl methacrylate) nanoparticles.

You JO, Auguste DT.

Biomaterials. 2008 Apr;29(12):1950-7. doi: 10.1016/j.biomaterials.2007.12.041. Epub 2008 Feb 5.

PMID:
18255142
41.

pH triggered release of protective poly(ethylene glycol)-b-polycation copolymers from liposomes.

Auguste DT, Armes SP, Brzezinska KR, Deming TJ, Kohn J, Prud'homme RK.

Biomaterials. 2006 Apr;27(12):2599-608. Epub 2005 Dec 27.

PMID:
16380161
42.

Association of hydrophobically-modified poly(ethylene glycol) with fusogenic liposomes.

Auguste DT, Prud'homme RK, Ahl PL, Meers P, Kohn J.

Biochim Biophys Acta. 2003 Oct 13;1616(2):184-95.

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