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Items: 34

1.

An immunosuppressive macrophage profile attenuates the prognostic impact of CD20-positive B cells in human soft tissue sarcoma.

Tsagozis P, Augsten M, Zhang Y, Li T, Hesla A, Bergh J, Haglund F, Tobin NP, Ehnman M.

Cancer Immunol Immunother. 2019 Jun;68(6):927-936. doi: 10.1007/s00262-019-02322-y. Epub 2019 Mar 16.

2.

A Novel ACKR2-Dependent Role of Fibroblast-Derived CXCL14 in Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer.

Sjöberg E, Meyrath M, Milde L, Herrera M, Lövrot J, Hägerstrand D, Frings O, Bartish M, Rolny C, Sonnhammer E, Chevigné A, Augsten M, Östman A.

Clin Cancer Res. 2019 Jun 15;25(12):3702-3717. doi: 10.1158/1078-0432.CCR-18-1294. Epub 2019 Mar 8.

PMID:
30850359
3.

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.

Stafford WC, Peng X, Olofsson MH, Zhang X, Luci DK, Lu L, Cheng Q, Trésaugues L, Dexheimer TS, Coussens NP, Augsten M, Ahlzén HM, Orwar O, Östman A, Stone-Elander S, Maloney DJ, Jadhav A, Simeonov A, Linder S, Arnér ESJ.

Sci Transl Med. 2018 Feb 14;10(428). pii: eaaf7444. doi: 10.1126/scitranslmed.aaf7444.

PMID:
29444979
4.

Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death.

Cheteh EH, Augsten M, Rundqvist H, Bianchi J, Sarne V, Egevad L, Bykov VJ, Östman A, Wiman KG.

Cell Death Dis. 2017 Jun 1;8(6):e2848. doi: 10.1038/cddis.2017.225.

5.

Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype.

Shen X, Burguillos MA, Osman AM, Frijhoff J, Carrillo-Jiménez A, Kanatani S, Augsten M, Saidi D, Rodhe J, Kavanagh E, Rongvaux A, Rraklli V, Nyman U, Holmberg J, Östman A, Flavell RA, Barragan A, Venero JL, Blomgren K, Joseph B.

Nat Immunol. 2016 Nov;17(11):1282-1290. doi: 10.1038/ni.3545. Epub 2016 Sep 12.

PMID:
27618552
6.

Expression of the chemokine CXCL14 in the tumour stroma is an independent marker of survival in breast cancer.

Sjöberg E, Augsten M, Bergh J, Jirström K, Östman A.

Br J Cancer. 2016 May 10;114(10):1117-24. doi: 10.1038/bjc.2016.104. Epub 2016 Apr 26.

7.

All trans-retinoic acid abrogates the pro-tumorigenic phenotype of prostate cancer tumor-associated macrophages.

Tsagozis P, Augsten M, Pisa P.

Int Immunopharmacol. 2014 Nov;23(1):8-13. doi: 10.1016/j.intimp.2014.07.037. Epub 2014 Aug 14.

PMID:
25130608
8.

Local and systemic protumorigenic effects of cancer-associated fibroblast-derived GDF15.

Bruzzese F, Hägglöf C, Leone A, Sjöberg E, Roca MS, Kiflemariam S, Sjöblom T, Hammarsten P, Egevad L, Bergh A, Ostman A, Budillon A, Augsten M.

Cancer Res. 2014 Jul 1;74(13):3408-17. doi: 10.1158/0008-5472.CAN-13-2259. Epub 2014 Apr 29.

9.

Cancer-associated fibroblasts as another polarized cell type of the tumor microenvironment.

Augsten M.

Front Oncol. 2014 Mar 27;4:62. doi: 10.3389/fonc.2014.00062. eCollection 2014. Review.

10.

Cancer-associated fibroblasts expressing CXCL14 rely upon NOS1-derived nitric oxide signaling for their tumor-supporting properties.

Augsten M, Sjöberg E, Frings O, Vorrink SU, Frijhoff J, Olsson E, Borg Å, Östman A.

Cancer Res. 2014 Jun 1;74(11):2999-3010. doi: 10.1158/0008-5472.CAN-13-2740. Epub 2014 Apr 7.

11.

Graded inhibition of oncogenic Ras-signaling by multivalent Ras-binding domains.

Augsten M, Böttcher A, Spanbroek R, Rubio I, Friedrich K.

Cell Commun Signal. 2014 Jan 2;12:1. doi: 10.1186/1478-811X-12-1.

12.

The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation.

Frijhoff J, Dagnell M, Augsten M, Beltrami E, Giorgio M, Östman A.

Free Radic Biol Med. 2014 Mar;68:268-77. doi: 10.1016/j.freeradbiomed.2013.12.022. Epub 2013 Dec 27.

PMID:
24378437
13.

Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling.

Dagnell M, Frijhoff J, Pader I, Augsten M, Boivin B, Xu J, Mandal PK, Tonks NK, Hellberg C, Conrad M, Arnér ES, Östman A.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13398-403. doi: 10.1073/pnas.1302891110. Epub 2013 Jul 30.

14.

Effect of acute exercise on prostate cancer cell growth.

Rundqvist H, Augsten M, Strömberg A, Rullman E, Mijwel S, Kharaziha P, Panaretakis T, Gustafsson T, Östman A.

PLoS One. 2013 Jul 5;8(7):e67579. doi: 10.1371/journal.pone.0067579. Print 2013.

15.

Sorafenib prolongs liver regeneration after hepatic resection in rats.

Mollbrink A, Augsten M, Hultcrantz R, Eriksson LC, Stål P.

J Surg Res. 2013 Oct;184(2):847-54. doi: 10.1016/j.jss.2013.04.062. Epub 2013 May 18.

PMID:
23726434
16.

Prognostic significance in breast cancer of a gene signature capturing stromal PDGF signaling.

Frings O, Augsten M, Tobin NP, Carlson J, Paulsson J, Pena C, Olsson E, Veerla S, Bergh J, Ostman A, Sonnhammer EL.

Am J Pathol. 2013 Jun;182(6):2037-47. doi: 10.1016/j.ajpath.2013.02.018. Epub 2013 Apr 10.

PMID:
23583284
17.

STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer.

Peña C, Céspedes MV, Lindh MB, Kiflemariam S, Mezheyeuski A, Edqvist PH, Hägglöf C, Birgisson H, Bojmar L, Jirström K, Sandström P, Olsson E, Veerla S, Gallardo A, Sjöblom T, Chang AC, Reddel RR, Mangues R, Augsten M, Ostman A.

Cancer Res. 2013 Feb 15;73(4):1287-97. doi: 10.1158/0008-5472.CAN-12-1875. Epub 2012 Dec 14.

18.

Comparison of contrast-enhanced multi-station MR angiography and digital subtraction angiography of the lower extremity arterial disease.

Burbelko M, Augsten M, Kalinowski MO, Heverhagen JT.

J Magn Reson Imaging. 2013 Jun;37(6):1427-35. doi: 10.1002/jmri.23944. Epub 2012 Nov 27.

PMID:
23188773
19.

Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells.

Kharaziha P, Rodriguez P, Li Q, Rundqvist H, Björklund AC, Augsten M, Ullén A, Egevad L, Wiklund P, Nilsson S, Kroemer G, Grander D, Panaretakis T.

Cell Death Dis. 2012 Jan 26;3:e262. doi: 10.1038/cddis.2012.1.

20.

Fetal HDL/apoE: a novel regulator of gene expression in human placental endothelial cells.

Augsten M, Hackl H, Ebner B, Chemelli A, Glatter O, Marsche G, Lang U, Desoye G, Wadsack C.

Physiol Genomics. 2011 Nov 21;43(22):1255-62. doi: 10.1152/physiolgenomics.00109.2011. Epub 2011 Sep 27.

PMID:
21954452
21.

A digest on the role of the tumor microenvironment in gastrointestinal cancers.

Augsten M, Hägglöf C, Peña C, Ostman A.

Cancer Microenviron. 2010 Mar 7;3(1):167-76. doi: 10.1007/s12307-010-0040-9.

22.

[Daytime sleepiness in patients with Obstructive Sleep Apnoea (OSA) - pathogenetic factors].

Koehler U, Apelt S, Augsten M, Dette F, Jerrentrup L, Langanke J, Cassel W.

Pneumologie. 2011 Mar;65(3):137-42. doi: 10.1055/s-0030-1255838. Epub 2010 Nov 26. Review. German.

23.

GAD1 is a biomarker for benign and malignant prostatic tissue.

Jaraj SJ, Augsten M, Häggarth L, Wester K, Pontén F, Ostman A, Egevad L.

Scand J Urol Nephrol. 2011 Feb;45(1):39-45. doi: 10.3109/00365599.2010.521189. Epub 2010 Nov 22.

PMID:
21091088
24.

[Sleep-disordered breathing in long-term opioid therapy].

Koehler U, Augsten M, Cassel W, Jerrentrup A, Nolte J, Dette F.

Dtsch Med Wochenschr. 2010 Jun;135(22):1125-8. doi: 10.1055/s-0030-1255135. Epub 2010 May 25. Review. German.

PMID:
20503139
25.

[Long-term opioid therapy and respiratory insufficiency during sleep].

Nolte JE, Dette F, Cassel W, Riese C, Augsten M, Koehler U.

Pneumologie. 2010 Apr;64(4):241-5. doi: 10.1055/s-0029-1243965. Epub 2010 Apr 7. Review. German.

26.

Forkhead box F1 regulates tumor-promoting properties of cancer-associated fibroblasts in lung cancer.

Saito RA, Micke P, Paulsson J, Augsten M, Peña C, Jönsson P, Botling J, Edlund K, Johansson L, Carlsson P, Jirström K, Miyazono K, Ostman A.

Cancer Res. 2010 Apr 1;70(7):2644-54. doi: 10.1158/0008-5472.CAN-09-3644. Epub 2010 Mar 16.

27.

CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth.

Augsten M, Hägglöf C, Olsson E, Stolz C, Tsagozis P, Levchenko T, Frederick MJ, Borg A, Micke P, Egevad L, Ostman A.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3414-9. doi: 10.1073/pnas.0813144106. Epub 2009 Feb 13.

28.

Cancer-associated fibroblasts and tumor growth--bystanders turning into key players.

Ostman A, Augsten M.

Curr Opin Genet Dev. 2009 Feb;19(1):67-73. doi: 10.1016/j.gde.2009.01.003. Epub 2009 Feb 9. Review.

PMID:
19211240
29.

Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.

Büttner S, Bitto A, Ring J, Augsten M, Zabrocki P, Eisenberg T, Jungwirth H, Hutter S, Carmona-Gutierrez D, Kroemer G, Winderickx J, Madeo F.

J Biol Chem. 2008 Mar 21;283(12):7554-60. doi: 10.1074/jbc.M708477200. Epub 2008 Jan 11.

31.

Live-cell imaging of endogenous Ras-GTP illustrates predominant Ras activation at the plasma membrane.

Augsten M, Pusch R, Biskup C, Rennert K, Wittig U, Beyer K, Blume A, Wetzker R, Friedrich K, Rubio I.

EMBO Rep. 2006 Jan;7(1):46-51.

32.
33.

[A method for the determination of thiocyanate in serum].

Augsten M, Depersdorff J.

Z Med Lab Diagn. 1982;23(4):226-8. German. No abstract available.

PMID:
7148078
34.

[Creatinine determination without deproteinization].

Depersdorff J, Augsten M.

Z Med Labortech. 1976;17(5):249-55. German. No abstract available.

PMID:
997712

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