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Items: 21

1.

Targeting NOTCH activation in small cell lung cancer through LSD1 inhibition.

Augert A, Eastwood E, Ibrahim AH, Wu N, Grunblatt E, Basom R, Liggitt D, Eaton KD, Martins R, Poirier JT, Rudin CM, Milletti F, Cheng WY, Mack F, MacPherson D.

Sci Signal. 2019 Feb 5;12(567). pii: eaau2922. doi: 10.1126/scisignal.aau2922.

PMID:
30723171
2.

Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition.

Jia D, Augert A, Kim DW, Eastwood E, Wu N, Ibrahim AH, Kim KB, Dunn CT, Pillai SPS, Gazdar AF, Bolouri H, Park KS, MacPherson D.

Cancer Discov. 2018 Nov;8(11):1422-1437. doi: 10.1158/2159-8290.CD-18-0385. Epub 2018 Sep 4.

PMID:
30181244
3.

Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance).

Augert A, Zhang Q, Bates B, Cui M, Wang X, Wildey G, Dowlati A, MacPherson D.

J Thorac Oncol. 2017 Apr;12(4):704-713. doi: 10.1016/j.jtho.2016.12.011. Epub 2016 Dec 19.

4.

The PLA2R1-JAK2 pathway upregulates ERRα and its mitochondrial program to exert tumor-suppressive action.

Griveau A, Devailly G, Eberst L, Navaratnam N, Le Calvé B, Ferrand M, Faull P, Augert A, Dante R, Vanacker JM, Vindrieux D, Bernard D.

Oncogene. 2016 Sep 22;35(38):5033-42. doi: 10.1038/onc.2016.43. Epub 2016 Apr 4.

PMID:
27041564
5.

Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape.

Wiel C, Gras B, Vindrieux D, Warnier M, Gitenay D, Le Calvé B, Ferrand M, Augert A, Bernard D.

Oncogene. 2016 Mar 24;35(12):1596-601. doi: 10.1038/onc.2015.218. Epub 2015 Jun 15.

PMID:
26073088
6.

Treating transcriptional addiction in small cell lung cancer.

Augert A, MacPherson D.

Cancer Cell. 2014 Dec 8;26(6):783-784. doi: 10.1016/j.ccell.2014.11.012.

7.

[New physiopathological roles for the PLA2R1 receptor in cancer and membranous nephropathy].

Girard CA, Seitz-Polski B, Dolla G, Augert A, Vindrieux D, Bernard D, Lambeau G.

Med Sci (Paris). 2014 May;30(5):519-25. doi: 10.1051/medsci/20143005014. Epub 2014 Jun 13. Review. French.

8.

Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence.

Wiel C, Lallet-Daher H, Gitenay D, Gras B, Le Calvé B, Augert A, Ferrand M, Prevarskaya N, Simonnet H, Vindrieux D, Bernard D.

Nat Commun. 2014 May 6;5:3792. doi: 10.1038/ncomms4792.

PMID:
24797322
9.

Repression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growth.

Vindrieux D, Devailly G, Augert A, Le Calvé B, Ferrand M, Pigny P, Payen L, Lambeau G, Perrais M, Aubert S, Simonnet H, Dante R, Bernard D.

Oncotarget. 2014 Feb 28;5(4):1004-13.

10.

PTEN is a potent suppressor of small cell lung cancer.

Cui M, Augert A, Rongione M, Conkrite K, Parazzoli S, Nikitin AY, Ingolia N, MacPherson D.

Mol Cancer Res. 2014 May;12(5):654-9. doi: 10.1158/1541-7786.MCR-13-0554. Epub 2014 Jan 30.

11.

Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis.

Wiel C, Augert A, Vincent DF, Gitenay D, Vindrieux D, Le Calvé B, Arfi V, Lallet-Daher H, Reynaud C, Treilleux I, Bartholin L, Lelievre E, Bernard D.

Cell Death Dis. 2013 Oct 10;4:e855. doi: 10.1038/cddis.2013.382.

12.

PLA2R1 mediates tumor suppression by activating JAK2.

Vindrieux D, Augert A, Girard CA, Gitenay D, Lallet-Daher H, Wiel C, Le Calvé B, Gras B, Ferrand M, Verbeke S, de Launoit Y, Leroy X, Puisieux A, Aubert S, Perrais M, Gelb M, Simonnet H, Lambeau G, Bernard D.

Cancer Res. 2013 Oct 15;73(20):6334-45. doi: 10.1158/0008-5472.CAN-13-0318. Epub 2013 Sep 5.

13.

PLA2R1 kills cancer cells by inducing mitochondrial stress.

Augert A, Vindrieux D, Girard CA, Le Calvé B, Gras B, Ferrand M, Bouchet BP, Puisieux A, de Launoit Y, Simonnet H, Lambeau G, Bernard D.

Free Radic Biol Med. 2013 Dec;65:969-977. doi: 10.1016/j.freeradbiomed.2013.08.177. Epub 2013 Aug 29.

PMID:
23994771
14.

Platelet-derived growth factor B induces senescence and transformation in normal human fibroblasts.

Vindrieux D, Gras B, Garcia-Belinchon M, Mourah S, Lebbe C, Augert A, Bernard D.

Aging (Albany NY). 2013 Jul;5(7):531-8.

15.

Potassium channel KCNA1 modulates oncogene-induced senescence and transformation.

Lallet-Daher H, Wiel C, Gitenay D, Navaratnam N, Augert A, Le Calvé B, Verbeke S, Carling D, Aubert S, Vindrieux D, Bernard D.

Cancer Res. 2013 Aug 15;73(16):5253-65. doi: 10.1158/0008-5472.CAN-12-3690. Epub 2013 Jun 17.

16.

NUAK1 links genomic instability and senescence.

Bernard D, Augert A.

Aging (Albany NY). 2010 Jun;2(6):317-9. No abstract available.

17.

Regulation of ploidy and senescence by the AMPK-related kinase NUAK1.

Humbert N, Navaratnam N, Augert A, Da Costa M, Martien S, Wang J, Martinez D, Abbadie C, Carling D, de Launoit Y, Gil J, Bernard D.

EMBO J. 2010 Jan 20;29(2):376-86. doi: 10.1038/emboj.2009.342. Epub 2009 Nov 19.

18.

[Senescent-associated factors: pro- and anti-tumoral actions].

Augert A, Bernard D.

Med Sci (Paris). 2009 Oct;25(10):789-90. doi: 10.1051/medsci/20092510789. French. No abstract available.

19.

A genetic screen identifies topoisomerase 1 as a regulator of senescence.

Humbert N, Martien S, Augert A, Da Costa M, Mauen S, Abbadie C, de Launoit Y, Gil J, Bernard D.

Cancer Res. 2009 May 15;69(10):4101-6. doi: 10.1158/0008-5472.CAN-08-2864. Epub 2009 May 12.

20.

The M-type receptor PLA2R regulates senescence through the p53 pathway.

Augert A, Payré C, de Launoit Y, Gil J, Lambeau G, Bernard D.

EMBO Rep. 2009 Mar;10(3):271-7. doi: 10.1038/embor.2008.255. Epub 2009 Feb 6.

21.

Chemokine signaling via the CXCR2 receptor reinforces senescence.

Acosta JC, O'Loghlen A, Banito A, Guijarro MV, Augert A, Raguz S, Fumagalli M, Da Costa M, Brown C, Popov N, Takatsu Y, Melamed J, d'Adda di Fagagna F, Bernard D, Hernando E, Gil J.

Cell. 2008 Jun 13;133(6):1006-18. doi: 10.1016/j.cell.2008.03.038.

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