Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 132

1.

The nutritional environment determines which and how intestinal stem cells contribute to homeostasis and tumorigenesis.

Li W, Zimmerman SE, Peregrina K, Houston M, Mayoral J, Zhang J, Maqbool S, Zhang Z, Cai Y, Ye K, Augenlicht LH.

Carcinogenesis. 2019 Aug 22;40(8):937-946. doi: 10.1093/carcin/bgz106.

PMID:
31169292
2.

Modelling western dietary habits in the mouse: easier said than done.

Fodde R, Schmitt M, Schewe M, Augenlicht LH.

Hepatobiliary Surg Nutr. 2017 Apr;6(2):138-140. doi: 10.21037/hbsn.2017.01.20. No abstract available.

3.

Environmental Impact on Intestinal Stem Cell Functions in Mucosal Homeostasis and Tumorigenesis.

Augenlicht LH.

J Cell Biochem. 2017 May;118(5):943-952. doi: 10.1002/jcb.25719. Epub 2017 Jan 11. Review.

4.

Calcium and 1,25-dihydroxyvitamin D3 modulate genes of immune and inflammatory pathways in the human colon: a human crossover trial.

Protiva P, Pendyala S, Nelson C, Augenlicht LH, Lipkin M, Holt PR.

Am J Clin Nutr. 2016 May;103(5):1224-31. doi: 10.3945/ajcn.114.105304. Epub 2016 Mar 23.

5.

The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner.

Shin J, Carr A, Corner GA, Tögel L, Dávalos-Salas M, Tran H, Chueh AC, Al-Obaidi S, Chionh F, Ahmed N, Buchanan DD, Young JP, Malo MS, Hodin RA, Arango D, Sieber OM, Augenlicht LH, Dhillon AS, Weber TK, Mariadason JM.

J Biol Chem. 2015 Jun 19;290(25):15392. doi: 10.1074/jbc.A114.557546. No abstract available.

6.

Real time analysis of metabolic profile in ex vivo mouse intestinal crypt organoid cultures.

Bas T, Augenlicht LH.

J Vis Exp. 2014 Nov 3;(93):e52026. doi: 10.3791/52026.

7.

Vitamin D is a determinant of mouse intestinal Lgr5 stem cell functions.

Peregrina K, Houston M, Daroqui C, Dhima E, Sellers RS, Augenlicht LH.

Carcinogenesis. 2015 Jan;36(1):25-31. doi: 10.1093/carcin/bgu221. Epub 2014 Oct 24.

8.

The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner.

Shin J, Carr A, Corner GA, Tögel L, Dávalos-Salas M, Tran H, Chueh AC, Al-Obaidi S, Chionh F, Ahmed N, Buchanan DD, Young JP, Malo MS, Hodin RA, Arango D, Sieber OM, Augenlicht LH, Dhillon AS, Weber TK, Mariadason JM.

J Biol Chem. 2014 Sep 5;289(36):25306-16. doi: 10.1074/jbc.M114.557546. Epub 2014 Jul 18. Erratum in: J Biol Chem. 2015 Jun 19;290(25):15392. Dávaos-Salas, Mercedes [Corrected to Dávalos-Salas, Mercedes].

9.

Circulating soluble cytokine receptors and colorectal cancer risk.

Ho GY, Wang T, Zheng SL, Tinker L, Xu J, Rohan TE, Wassertheil-Smoller S, Xue X, Augenlicht LH, Peters U, Phipps AI, Strickler HD, Gunter MJ, Cushman M.

Cancer Epidemiol Biomarkers Prev. 2014 Jan;23(1):179-88. doi: 10.1158/1055-9965.EPI-13-0545. Epub 2013 Nov 5.

10.

Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals.

Shan M, Gentile M, Yeiser JR, Walland AC, Bornstein VU, Chen K, He B, Cassis L, Bigas A, Cols M, Comerma L, Huang B, Blander JM, Xiong H, Mayer L, Berin C, Augenlicht LH, Velcich A, Cerutti A.

Science. 2013 Oct 25;342(6157):447-53. doi: 10.1126/science.1237910. Epub 2013 Sep 26.

11.

The effect of lung cancer on cytokine expression in peripheral blood mononuclear cells.

Chang DH, Rutledge JR, Patel AA, Heerdt BG, Augenlicht LH, Korst RJ.

PLoS One. 2013 Jun 6;8(6):e64456. doi: 10.1371/journal.pone.0064456. Print 2013.

12.

Abdominal obesity, independent from caloric intake, accounts for the development of intestinal tumors in Apc(1638N/+) female mice.

Huffman DM, Augenlicht LH, Zhang X, Lofrese JJ, Atzmon G, Chamberland JP, Mantzoros CS.

Cancer Prev Res (Phila). 2013 Mar;6(3):177-87. doi: 10.1158/1940-6207.CAPR-12-0414.

13.

Dietary cholecalciferol and calcium levels in a Western-style defined rodent diet alter energy metabolism and inflammatory responses in mice.

Bastie CC, Gaffney-Stomberg E, Lee TW, Dhima E, Pessin JE, Augenlicht LH.

J Nutr. 2012 May;142(5):859-65. doi: 10.3945/jn.111.149914. Epub 2012 Mar 21.

14.

Intrinsic mitochondrial membrane potential and associated tumor phenotype are independent of MUC1 over-expression.

Houston MA, Augenlicht LH, Heerdt BG.

PLoS One. 2011;6(9):e25207. doi: 10.1371/journal.pone.0025207. Epub 2011 Sep 23.

15.

Intestinal epithelial-specific PTEN inactivation results in tumor formation.

Byun DS, Ahmed N, Nasser S, Shin J, Al-Obaidi S, Goel S, Corner GA, Wilson AJ, Flanagan DJ, Williams DS, Augenlicht LH, Vincan E, Mariadason JM.

Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G856-64. doi: 10.1152/ajpgi.00178.2011. Epub 2011 Aug 11.

16.

Stable differences in intrinsic mitochondrial membrane potential of tumor cell subpopulations reflect phenotypic heterogeneity.

Houston MA, Augenlicht LH, Heerdt BG.

Int J Cell Biol. 2011;2011:978583. doi: 10.1155/2011/978583. Epub 2011 Jul 2.

17.

Mybl2, downregulated during colon epithelial cell maturation, is suppressed by miR-365.

Papetti M, Augenlicht LH.

Am J Physiol Gastrointest Liver Physiol. 2011 Sep;301(3):G508-18. doi: 10.1152/ajpgi.00066.2011. Epub 2011 Jul 7.

18.

Paneth cell marker expression in intestinal villi and colon crypts characterizes dietary induced risk for mouse sporadic intestinal cancer.

Wang D, Peregrina K, Dhima E, Lin EY, Mariadason JM, Augenlicht LH.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10272-7. doi: 10.1073/pnas.1017668108. Epub 2011 Jun 7.

19.

MYBL2, a link between proliferation and differentiation in maturing colon epithelial cells.

Papetti M, Augenlicht LH.

J Cell Physiol. 2011 Mar;226(3):785-91. doi: 10.1002/jcp.22399.

20.

Transcriptional attenuation in colon carcinoma cells in response to butyrate.

Daroqui MC, Augenlicht LH.

Cancer Prev Res (Phila). 2010 Oct;3(10):1292-302. doi: 10.1158/1940-6207.CAPR-10-0083. Epub 2010 Sep 14.

21.

Prediction and testing of biological networks underlying intestinal cancer.

Patel VN, Bebek G, Mariadason JM, Wang D, Augenlicht LH, Chance MR.

PLoS One. 2010 Sep 1;5(9). pii: e12497. doi: 10.1371/journal.pone.0012497.

22.

Oxaliplatin resistance induced by ERCC1 up-regulation is abrogated by siRNA-mediated gene silencing in human colorectal cancer cells.

Seetharam RN, Sood A, Basu-Mallick A, Augenlicht LH, Mariadason JM, Goel S.

Anticancer Res. 2010 Jul;30(7):2531-8.

PMID:
20682979
23.

Altered dynamics of intestinal cell maturation in Apc1638N/+ mice.

Wang D, Pezo RC, Corner G, Sison C, Lesser ML, Shenoy SM, Mariadason JM, Singer RH, Augenlicht LH.

Cancer Res. 2010 Jul 1;70(13):5348-57. doi: 10.1158/0008-5472.CAN-09-4593. Epub 2010 Jun 22.

24.

Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction.

Wilson AJ, Chueh AC, Tögel L, Corner GA, Ahmed N, Goel S, Byun DS, Nasser S, Houston MA, Jhawer M, Smartt HJ, Murray LB, Nicholas C, Heerdt BG, Arango D, Augenlicht LH, Mariadason JM.

Cancer Res. 2010 Jan 15;70(2):609-20. doi: 10.1158/0008-5472.CAN-09-2327. Epub 2010 Jan 12.

25.

Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling.

Guilmeau S, Flandez M, Mariadason JM, Augenlicht LH.

Oncogene. 2010 Feb 18;29(7):992-1002. doi: 10.1038/onc.2009.393. Epub 2009 Nov 23.

PMID:
19935714
26.

Gene expression profiling of primary and metastatic colon cancers identifies a reduced proliferative rate in metastatic tumors.

Ganepola GA, Mazziotta RM, Weeresinghe D, Corner GA, Parish CJ, Chang DH, Tebbutt NC, Murone C, Ahmed N, Augenlicht LH, Mariadason JM.

Clin Exp Metastasis. 2010;27(1):1-9. doi: 10.1007/s10585-009-9295-2. Epub 2009 Nov 1.

PMID:
19882219
27.

An A13 repeat within the 3'-untranslated region of epidermal growth factor receptor (EGFR) is frequently mutated in microsatellite instability colon cancers and is associated with increased EGFR expression.

Yuan Z, Shin J, Wilson A, Goel S, Ling YH, Ahmed N, Dopeso H, Jhawer M, Nasser S, Montagna C, Fordyce K, Augenlicht LH, Aaltonen LA, Arango D, Weber TK, Mariadason JM.

Cancer Res. 2009 Oct 1;69(19):7811-8. doi: 10.1158/0008-5472.CAN-09-0986. Epub 2009 Sep 29. Erratum in: Cancer Res. 2010 Feb 1;70(3):1275.

28.

PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.

Pysz MA, Leontieva OV, Bateman NW, Uronis JM, Curry KJ, Threadgill DW, Janssen KP, Robine S, Velcich A, Augenlicht LH, Black AR, Black JD.

Exp Cell Res. 2009 May 1;315(8):1415-28. doi: 10.1016/j.yexcr.2009.02.002. Epub 2009 Feb 14.

29.

Butyrate and vitamin D3 induce transcriptional attenuation at the cyclin D1 locus in colonic carcinoma cells.

Maier S, Daroqui MC, Scherer S, Roepcke S, Velcich A, Shenoy SM, Singer RH, Augenlicht LH.

J Cell Physiol. 2009 Mar;218(3):638-42. doi: 10.1002/jcp.21642.

30.

Western-style diet-induced colonic tumors and their modulation by calcium and vitamin D in C57Bl/6 mice: a preclinical model for human sporadic colon cancer.

Newmark HL, Yang K, Kurihara N, Fan K, Augenlicht LH, Lipkin M.

Carcinogenesis. 2009 Jan;30(1):88-92. doi: 10.1093/carcin/bgn229. Epub 2008 Nov 18.

31.

KLF4 regulation in intestinal epithelial cell maturation.

Flandez M, Guilmeau S, Blache P, Augenlicht LH.

Exp Cell Res. 2008 Dec 10;314(20):3712-23. doi: 10.1016/j.yexcr.2008.10.004. Epub 2008 Oct 21.

32.

Proteomic changes during intestinal cell maturation in vivo.

Chang J, Chance MR, Nicholas C, Ahmed N, Guilmeau S, Flandez M, Wang D, Byun DS, Nasser S, Albanese JM, Corner GA, Heerdt BG, Wilson AJ, Augenlicht LH, Mariadason JM.

J Proteomics. 2008 Dec 2;71(5):530-46. doi: 10.1016/j.jprot.2008.08.003. Epub 2008 Sep 12.

33.

HDAC4 promotes growth of colon cancer cells via repression of p21.

Wilson AJ, Byun DS, Nasser S, Murray LB, Ayyanar K, Arango D, Figueroa M, Melnick A, Kao GD, Augenlicht LH, Mariadason JM.

Mol Biol Cell. 2008 Oct;19(10):4062-75. doi: 10.1091/mbc.E08-02-0139. Epub 2008 Jul 16.

34.

Intestinal deletion of Pofut1 in the mouse inactivates notch signaling and causes enterocolitis.

Guilmeau S, Flandez M, Bancroft L, Sellers RS, Tear B, Stanley P, Augenlicht LH.

Gastroenterology. 2008 Sep;135(3):849-60, 860.e1-6. doi: 10.1053/j.gastro.2008.05.050. Epub 2008 May 21.

35.

Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors.

Pezo RC, Gandhi SJ, Shirley LA, Pestell RG, Augenlicht LH, Singer RH.

Cancer Res. 2008 Jul 1;68(13):4977-82. doi: 10.1158/0008-5472.CAN-07-6770.

36.

Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation.

Bi X, Tong C, Dockendorff A, Bancroft L, Gallagher L, Guzman G, Iozzo RV, Augenlicht LH, Yang W.

Carcinogenesis. 2008 Jul;29(7):1435-40. doi: 10.1093/carcin/bgn141. Epub 2008 Jun 12.

37.

Expression of selenium-binding protein 1 characterizes intestinal cell maturation and predicts survival for patients with colorectal cancer.

Li T, Yang W, Li M, Byun DS, Tong C, Nasser S, Zhuang M, Arango D, Mariadason JM, Augenlicht LH.

Mol Nutr Food Res. 2008 Nov;52(11):1289-99. doi: 10.1002/mnfr.200700331.

PMID:
18435490
38.

PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab.

Jhawer M, Goel S, Wilson AJ, Montagna C, Ling YH, Byun DS, Nasser S, Arango D, Shin J, Klampfer L, Augenlicht LH, Perez-Soler R, Mariadason JM.

Cancer Res. 2008 Mar 15;68(6):1953-61. doi: 10.1158/0008-5472.CAN-07-5659. Erratum in: Cancer Res. 2008 Aug 15;68(16):6859. Soler, Roman Perez [corrected to Perez-Soler, Roman]. Cancer Res. 2009 Dec 1;69(23):9156.

39.

Sulindac suppresses beta-catenin expression in human cancer cells.

Han A, Song Z, Tong C, Hu D, Bi X, Augenlicht LH, Yang W.

Eur J Pharmacol. 2008 Mar 31;583(1):26-31. doi: 10.1016/j.ejphar.2007.12.034. Epub 2008 Feb 5.

40.

p27kip1 Regulates cdk2 activity in the proliferating zone of the mouse intestinal epithelium: potential role in neoplasia.

Smartt HJ, Guilmeau S, Nasser SV, Nicholas C, Bancroft L, Simpson SA, Yeh N, Yang W, Mariadason JM, Koff A, Augenlicht LH.

Gastroenterology. 2007 Jul;133(1):232-43. Epub 2007 Apr 25.

PMID:
17631145
41.

c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression.

Tong C, Yin Z, Song Z, Dockendorff A, Huang C, Mariadason J, Flavell RA, Davis RJ, Augenlicht LH, Yang W.

Am J Pathol. 2007 Jul;171(1):297-303.

42.

Drug-induced inactivation or gene silencing of class I histone deacetylases suppresses ovarian cancer cell growth: implications for therapy.

Khabele D, Son DS, Parl AK, Goldberg GL, Augenlicht LH, Mariadason JM, Rice VM.

Cancer Biol Ther. 2007 May;6(5):795-801. Epub 2007 Feb 14.

PMID:
17387270
43.

JNK1 is required for sulindac-mediated inhibition of cell proliferation and induction of apoptosis in vitro and in vivo.

Song Z, Tong C, Liang J, Dockendorff A, Huang C, Augenlicht LH, Yang W.

Eur J Pharmacol. 2007 Apr 10;560(2-3):95-100. Epub 2007 Jan 19.

44.

Interaction of genetic and dietary factors in mouse intestinal tumorigenesis.

Augenlicht LH, Yang W, Mariadason J, Velcich A, Klampfer L, Lipkin M, Yang K.

J Nutr. 2006 Oct;136(10):2695S-6S. No abstract available.

PMID:
16988154
45.

Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT.

Paroder V, Spencer SR, Paroder M, Arango D, Schwartz S Jr, Mariadason JM, Augenlicht LH, Eskandari S, Carrasco N.

Proc Natl Acad Sci U S A. 2006 May 9;103(19):7270-5. Epub 2006 May 2.

46.

Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer.

Wilson AJ, Byun DS, Popova N, Murray LB, L'Italien K, Sowa Y, Arango D, Velcich A, Augenlicht LH, Mariadason JM.

J Biol Chem. 2006 May 12;281(19):13548-58. Epub 2006 Mar 13.

47.
48.

Kaiso-deficient mice show resistance to intestinal cancer.

Prokhortchouk A, Sansom O, Selfridge J, Caballero IM, Salozhin S, Aithozhina D, Cerchietti L, Meng FG, Augenlicht LH, Mariadason JM, Hendrich B, Melnick A, Prokhortchouk E, Clarke A, Bird A.

Mol Cell Biol. 2006 Jan;26(1):199-208.

49.

Pathways in nutritional modulation of homeostasis and tumorigenesis.

Augenlicht LH.

J Nutr. 2005 Dec;135(12 Suppl):3025S-3026S. doi: 10.1093/jn/135.12.3025S. Review. No abstract available.

PMID:
16317165
50.

Supplemental Content

Loading ...
Support Center