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Items: 1 to 50 of 202

2.

Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.

Veigel D, Wagner R, Stübiger G, Wuczkowski M, Filipits M, Horvat R, Benhamú B, López-Rodríguez ML, Leisser A, Valent P, Grusch M, Hegardt FG, García J, Serra D, Auersperg N, Colomer R, Grunt TW.

Int J Cancer. 2015 May 1;136(9):2078-90. doi: 10.1002/ijc.29261. Epub 2014 Nov 3.

3.
4.

Ovarian surface epithelium as a source of ovarian cancers: unwarranted speculation or evidence-based hypothesis?

Auersperg N.

Gynecol Oncol. 2013 Jul;130(1):246-51. doi: 10.1016/j.ygyno.2013.03.021. Epub 2013 Apr 2. Review.

PMID:
23558054
5.

The origin of ovarian cancers--hypotheses and controversies.

Auersperg N.

Front Biosci (Schol Ed). 2013 Jan 1;5:709-19. Review.

6.

TGF-beta induces serous borderline ovarian tumor cell invasion by activating EMT but triggers apoptosis in low-grade serous ovarian carcinoma cells.

Cheng JC, Auersperg N, Leung PC.

PLoS One. 2012;7(8):e42436. doi: 10.1371/journal.pone.0042436. Epub 2012 Aug 15.

7.

EGF-induced EMT and invasiveness in serous borderline ovarian tumor cells: a possible step in the transition to low-grade serous carcinoma cells?

Cheng JC, Auersperg N, Leung PC.

PLoS One. 2012;7(3):e34071. doi: 10.1371/journal.pone.0034071. Epub 2012 Mar 30.

8.

HOXA4 protein levels and localization in the aorta and in human abdominal aortic aneurysms.

Klausen C, Auersperg N.

BMC Physiol. 2011 Dec 14;11:18. doi: 10.1186/1472-6793-11-18.

9.

Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells.

Cheng JC, Auersperg N, Leung PC.

Oncogene. 2011 Sep 15;30(37):3930-42. doi: 10.1038/onc.2011.117. Epub 2011 Apr 11.

PMID:
21478913
10.

The origin of ovarian carcinomas: a unifying hypothesis.

Auersperg N.

Int J Gynecol Pathol. 2011 Jan;30(1):12-21. doi: 10.1097/PGP.0b013e3181f45f3e.

PMID:
21131839
11.

Inhibition of p53 induces invasion of serous borderline ovarian tumor cells by accentuating PI3K/Akt-mediated suppression of E-cadherin.

Cheng JC, Auersperg N, Leung PC.

Oncogene. 2011 Mar 3;30(9):1020-31. doi: 10.1038/onc.2010.486. Epub 2010 Oct 25.

PMID:
20972462
12.

Oviductal glycoprotein (OVGP1, MUC9): a differentiation-based mucin present in serum of women with ovarian cancer.

Maines-Bandiera S, Woo MM, Borugian M, Molday LL, Hii T, Gilks B, Leung PC, Molday RS, Auersperg N.

Int J Gynecol Cancer. 2010 Jan;20(1):16-22. doi: 10.1111/IGC.0b013e3181bcc96d.

PMID:
20130498
13.

Induction of papillary carcinoma in human ovarian surface epithelial cells using combined genetic elements and peritoneal microenvironment.

Zheng J, Mercado-Uribe I, Rosen DG, Chang B, Liu P, Yang G, Malpica A, Naora H, Auersperg N, Mills GB, Bast RC, Liu J.

Cell Cycle. 2010 Jan 1;9(1):140-6. Epub 2010 Jan 5.

14.

Cell motility and spreading are suppressed by HOXA4 in ovarian cancer cells: possible involvement of beta1 integrin.

Klausen C, Leung PC, Auersperg N.

Mol Cancer Res. 2009 Sep;7(9):1425-37. doi: 10.1158/1541-7786.MCR-08-0466. Epub 2009 Sep 1.

15.

Effects of growth differentiation factor 9 on cell cycle regulators and ERK42/44 in human granulosa cell proliferation.

Huang Q, Cheung AP, Zhang Y, Huang HF, Auersperg N, Leung PC.

Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1344-53. doi: 10.1152/ajpendo.90929.2008. Epub 2009 Apr 14.

16.

Expression and function of HOXA genes in normal and neoplastic ovarian epithelial cells.

Ota T, Klausen C, Salamanca MC, Woo HL, Leung PC, Auersperg N.

Differentiation. 2009 Feb;77(2):162-71. doi: 10.1016/j.diff.2008.09.018. Epub 2008 Oct 25.

PMID:
19281776
17.

HOX cofactors expression and regulation in the human ovary.

Ota T, Asahina H, Park SH, Huang Q, Minegishi T, Auersperg N, Leung PC.

Reprod Biol Endocrinol. 2008 Oct 30;6:49. doi: 10.1186/1477-7827-6-49.

18.

SV40 early genes induce neoplastic properties in serous borderline ovarian tumor cells.

Woo MM, Salamanca CM, Symowicz J, Stack MS, Miller DM, Leung PC, Gilks CB, Auersperg N.

Gynecol Oncol. 2008 Oct;111(1):125-31. doi: 10.1016/j.ygyno.2008.06.021. Epub 2008 Aug 3.

PMID:
18678400
19.

The eukaryotic translation elongation factor eEF1A2 induces neoplastic properties and mediates tumorigenic effects of ZNF217 in precursor cells of human ovarian carcinomas.

Sun Y, Wong N, Guan Y, Salamanca CM, Cheng JC, Lee JM, Gray JW, Auersperg N.

Int J Cancer. 2008 Oct 15;123(8):1761-9. doi: 10.1002/ijc.23708.

20.

The origin of ovarian carcinomas: a developmental view.

Auersperg N, Woo MM, Gilks CB.

Gynecol Oncol. 2008 Sep;110(3):452-4. doi: 10.1016/j.ygyno.2008.05.031. Epub 2008 Jul 7. No abstract available.

PMID:
18603285
21.

Role of PELP1/MNAR signaling in ovarian tumorigenesis.

Dimple C, Nair SS, Rajhans R, Pitcheswara PR, Liu J, Balasenthil S, Le XF, Burow ME, Auersperg N, Tekmal RR, Broaddus RR, Vadlamudi RK.

Cancer Res. 2008 Jun 15;68(12):4902-9. doi: 10.1158/0008-5472.CAN-07-5698.

22.

Ovarian cancer: linking genomics to new target discovery and molecular markers--the way ahead.

Hennessy BT, Murph M, Nanjundan M, Carey M, Auersperg N, Almeida J, Coombes KR, Liu J, Lu Y, Gray JW, Mills GB.

Adv Exp Med Biol. 2008;617:23-40. doi: 10.1007/978-0-387-69080-3_3. Review. No abstract available.

23.

Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer.

Astanehe A, Arenillas D, Wasserman WW, Leung PC, Dunn SE, Davies BR, Mills GB, Auersperg N.

J Cell Sci. 2008 Mar 1;121(Pt 5):664-74. doi: 10.1242/jcs.013029. Epub 2008 Feb 12.

24.

Serous borderline ovarian tumors in long-term culture: phenotypic and genotypic distinction from invasive ovarian carcinomas.

Woo MM, Salamanca CM, Miller M, Symowicz J, Leung PC, Oliveira C, Ehlen TG, Gilks CB, Huntsman D, Auersperg N.

Int J Gynecol Cancer. 2008 Nov-Dec;18(6):1234-47. doi: 10.1111/j.1525-1438.2007.01171.x. Epub 2008 Jan 23.

PMID:
18217967
25.

HOXA7 in epithelial ovarian cancer: interrelationships between differentiation and clinical features.

Ota T, Gilks CB, Longacre T, Leung PC, Auersperg N.

Reprod Sci. 2007 Sep;14(6):605-14.

PMID:
17959889
26.

Differential role of gonadotropin-releasing hormone on human ovarian epithelial cancer cell invasion.

Chen CL, Cheung LW, Lau MT, Choi JH, Auersperg N, Wang HS, Wong AS, Leung PC.

Endocrine. 2007 Jun;31(3):311-20.

PMID:
17906381
27.

The morphogenic function of E-cadherin-mediated adherens junctions in epithelial ovarian carcinoma formation and progression.

Wu C, Cipollone J, Maines-Bandiera S, Tan C, Karsan A, Auersperg N, Roskelley CD.

Differentiation. 2008 Feb;76(2):193-205. Epub 2007 Jul 2.

PMID:
17608733
28.

An improved assay to quantitate the invasiveness of cells in modified Boyden chambers.

Woo MM, Salamanca CM, Minor A, Auersperg N.

In Vitro Cell Dev Biol Anim. 2007 Jan;43(1):7-9.

PMID:
17570027
29.

Modulation of angiogenic phenotype alters tumorigenicity in rat ovarian epithelial cells.

Schumacher JJ, Dings RP, Cosin J, Subramanian IV, Auersperg N, Ramakrishnan S.

Cancer Res. 2007 Apr 15;67(8):3683-90.

30.

Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro.

He X, Pool M, Darcy KM, Lim SB, Auersperg N, Coon JS, Beck WT.

Oncogene. 2007 Jul 26;26(34):4961-8. Epub 2007 Feb 19.

31.

Multiple roles of the candidate oncogene ZNF217 in ovarian epithelial neoplastic progression.

Li P, Maines-Bandiera S, Kuo WL, Guan Y, Sun Y, Hills M, Huang G, Collins CC, Leung PC, Gray JW, Auersperg N.

Int J Cancer. 2007 May 1;120(9):1863-73.

32.

Immunolocalization of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and type I GnRH receptor during follicular development in the human ovary.

Choi JH, Gilks CB, Auersperg N, Leung PC.

J Clin Endocrinol Metab. 2006 Nov;91(11):4562-70. Epub 2006 Sep 5.

PMID:
16954155
33.

Pigment epithelium-derived factor is estrogen sensitive and inhibits the growth of human ovarian cancer and ovarian surface epithelial cells.

Cheung LW, Au SC, Cheung AN, Ngan HY, Tombran-Tink J, Auersperg N, Wong AS.

Endocrinology. 2006 Sep;147(9):4179-91. Epub 2006 Jun 15.

PMID:
16777976
38.

4-HPR modulates gene expression in ovarian cells.

Brewer M, Kirkpatrick ND, Wharton JT, Wang J, Hatch K, Auersperg N, Utzinger U, Gershenson D, Bast R, Zou C.

Int J Cancer. 2006 Sep 1;119(5):1005-13.

39.

Cell type- and stage-specific changes in HOXA7 protein expression in human ovarian folliculogenesis: possible role of GDF-9.

Ota T, Choi KB, Gilks CB, Leung PC, Auersperg N.

Differentiation. 2006 Feb;74(1):1-10.

PMID:
16466395
40.

Molecular pathways regulating EGF-induced epithelio-mesenchymal transition in human ovarian surface epithelium.

Ahmed N, Maines-Bandiera S, Quinn MA, Unger WG, Dedhar S, Auersperg N.

Am J Physiol Cell Physiol. 2006 Jun;290(6):C1532-42. Epub 2006 Jan 4.

41.

Caspase-1alpha is down-regulated in human ovarian cancer cells and the overexpression of caspase-1alpha induces apoptosis.

Feng Q, Li P, Salamanca C, Huntsman D, Leung PC, Auersperg N.

Cancer Res. 2005 Oct 1;65(19):8591-6.

43.

Proteomic analysis of a preneoplastic phenotype in ovarian surface epithelial cells derived from prophylactic oophorectomies.

He QY, Zhou Y, Wong E, Ehlen TG, Auersperg N, Chiu JF, Wong AS.

Gynecol Oncol. 2005 Jul;98(1):68-76.

PMID:
15913737
44.

In vitro model of normal, immortalized ovarian surface epithelial and ovarian cancer cells for chemoprevention of ovarian cancer.

Brewer M, Wharton JT, Wang J, McWatters A, Auersperg N, Gershenson D, Bast R, Zou C.

Gynecol Oncol. 2005 Aug;98(2):182-92.

PMID:
15907982
45.

Re: "Cultures of ovarian surface epithelium from women with and without a hereditary predisposition to develop female adnexal carcinoma".

Auersperg N.

Gynecol Oncol. 2005 Apr;97(1):302-4; author reply 304-5. No abstract available.

PMID:
15790484
46.

Cyclooxygenase-2 functions as a downstream mediator of lysophosphatidic acid to promote aggressive behavior in ovarian carcinoma cells.

Symowicz J, Adley BP, Woo MM, Auersperg N, Hudson LG, Stack MS.

Cancer Res. 2005 Mar 15;65(6):2234-42.

48.
49.

Proteome changes in ovarian epithelial cells derived from women with BRCA1 mutations and family histories of cancer.

Smith-Beckerman DM, Fung KW, Williams KE, Auersperg N, Godwin AK, Burlingame AL.

Mol Cell Proteomics. 2005 Feb;4(2):156-68. Epub 2004 Dec 9.

50.

Gain of OGP, an estrogen-regulated oviduct-specific glycoprotein, is associated with the development of endometrial hyperplasia and endometrial cancer.

Woo MM, Alkushi A, Verhage HG, Magliocco AM, Leung PC, Gilks CB, Auersperg N.

Clin Cancer Res. 2004 Dec 1;10(23):7958-64.

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