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Items: 42

1.

Deletion of Adam6 in Mus musculus leads to male subfertility and deficits in sperm ascent into the oviduct.

Voronina VA, Harris FM, Schmahl J, Galligan C, Oristian D, Zamfirova R, Gong G, Bai Y, Fury W, Rajamani S, Walls JR, Poueymirou WT, Esau L, Gale NW, Auerbach W, Murphy AJ, Macdonald LE.

Biol Reprod. 2019 Mar 1;100(3):686-696. doi: 10.1093/biolre/ioy210.

PMID:
30289441
2.

Injecting Embryonic Stem Cells into Eight-Cell-Stage Mouse Embryos.

Auerbach W, DeChiara TM.

Cold Spring Harb Protoc. 2017 Sep 1;2017(9):pdb.prot094367. doi: 10.1101/pdb.prot094367.

PMID:
28864571
3.

C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice.

Atanasio A, Decman V, White D, Ramos M, Ikiz B, Lee HC, Siao CJ, Brydges S, LaRosa E, Bai Y, Fury W, Burfeind P, Zamfirova R, Warshaw G, Orengo J, Oyejide A, Fralish M, Auerbach W, Poueymirou W, Freudenberg J, Gong G, Zambrowicz B, Valenzuela D, Yancopoulos G, Murphy A, Thurston G, Lai KM.

Sci Rep. 2016 Mar 16;6:23204. doi: 10.1038/srep23204.

4.

Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs.

Lai KM, Gong G, Atanasio A, Rojas J, Quispe J, Posca J, White D, Huang M, Fedorova D, Grant C, Miloscio L, Droguett G, Poueymirou WT, Auerbach W, Yancopoulos GD, Frendewey D, Rinn J, Valenzuela DM.

PLoS One. 2015 Apr 24;10(4):e0125522. doi: 10.1371/journal.pone.0125522. eCollection 2015.

5.

Generation of fertile and fecund F0 XY female mice from XY ES cells.

Kuno J, Poueymirou WT, Gong G, Siao CJ, Clarke G, Esau L, Kojak N, Posca J, Atanasio A, Strein J, Yancopoulos GD, Lai KM, DeChiara TM, Frendewey D, Auerbach W, Valenzuela DM.

Transgenic Res. 2015 Feb;24(1):19-29. doi: 10.1007/s11248-014-9815-y. Epub 2014 Aug 3.

PMID:
25087174
6.

Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes.

Macdonald LE, Karow M, Stevens S, Auerbach W, Poueymirou WT, Yasenchak J, Frendewey D, Valenzuela DM, Giallourakis CC, Alt FW, Yancopoulos GD, Murphy AJ.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5147-52. doi: 10.1073/pnas.1323896111. Epub 2014 Mar 25.

7.

Conditionals by inversion provide a universal method for the generation of conditional alleles.

Economides AN, Frendewey D, Yang P, Dominguez MG, Dore AT, Lobov IB, Persaud T, Rojas J, McClain J, Lengyel P, Droguett G, Chernomorsky R, Stevens S, Auerbach W, Dechiara TM, Pouyemirou W, Cruz JM Jr, Feeley K, Mellis IA, Yasenchack J, Hatsell SJ, Xie L, Latres E, Huang L, Zhang Y, Pefanis E, Skokos D, Deckelbaum RA, Croll SD, Davis S, Valenzuela DM, Gale NW, Murphy AJ, Yancopoulos GD.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3179-88. doi: 10.1073/pnas.1217812110. Epub 2013 Aug 5.

8.

Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo.

Rongvaux A, Willinger T, Takizawa H, Rathinam C, Auerbach W, Murphy AJ, Valenzuela DM, Yancopoulos GD, Eynon EE, Stevens S, Manz MG, Flavell RA.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2378-83. doi: 10.1073/pnas.1019524108. Epub 2011 Jan 24.

9.

Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung.

Willinger T, Rongvaux A, Takizawa H, Yancopoulos GD, Valenzuela DM, Murphy AJ, Auerbach W, Eynon EE, Stevens S, Manz MG, Flavell RA.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2390-5. doi: 10.1073/pnas.1019682108. Epub 2011 Jan 24.

10.

Producing fully ES cell-derived mice from eight-cell stage embryo injections.

DeChiara TM, Poueymirou WT, Auerbach W, Frendewey D, Yancopoulos GD, Valenzuela DM.

Methods Enzymol. 2010;476:285-94. doi: 10.1016/S0076-6879(10)76016-X.

PMID:
20691872
11.

Embryonic stem cell tumor model reveals role of vascular endothelial receptor tyrosine phosphatase in regulating Tie2 pathway in tumor angiogenesis.

Li Z, Huang H, Boland P, Dominguez MG, Burfeind P, Lai KM, Lin HC, Gale NW, Daly C, Auerbach W, Valenzuela D, Yancopoulos GD, Thurston G.

Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22399-404. doi: 10.1073/pnas.0911189106. Epub 2009 Dec 15.

12.

VelociMouse: fully ES cell-derived F0-generation mice obtained from the injection of ES cells into eight-cell-stage embryos.

Dechiara TM, Poueymirou WT, Auerbach W, Frendewey D, Yancopoulos GD, Valenzuela DM.

Methods Mol Biol. 2009;530:311-24. doi: 10.1007/978-1-59745-471-1_16.

PMID:
19266341
13.

F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses.

Poueymirou WT, Auerbach W, Frendewey D, Hickey JF, Escaravage JM, Esau L, Doré AT, Stevens S, Adams NC, Dominguez MG, Gale NW, Yancopoulos GD, DeChiara TM, Valenzuela DM.

Nat Biotechnol. 2007 Jan;25(1):91-9. Epub 2006 Dec 24.

PMID:
17187059
14.

Recycling to the plasma membrane is delayed in EHD1 knockout mice.

Rapaport D, Auerbach W, Naslavsky N, Pasmanik-Chor M, Galperin E, Fein A, Caplan S, Joyner AL, Horowitz M.

Traffic. 2006 Jan;7(1):52-60.

15.

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6.

Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, Cheng HL, Kennedy C, Nunez N, Bronson R, Frendewey D, Auerbach W, Valenzuela D, Karow M, Hottiger MO, Hursting S, Barrett JC, Guarente L, Mulligan R, Demple B, Yancopoulos GD, Alt FW.

Cell. 2006 Jan 27;124(2):315-29.

16.

The exon 8-containing prosaposin gene splice variant is dispensable for mouse development, lysosomal function, and secretion.

Cohen T, Auerbach W, Ravid L, Bodennec J, Fein A, Futerman AH, Joyner AL, Horowitz M.

Mol Cell Biol. 2005 Mar;25(6):2431-40.

17.

Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality.

Hopkins KM, Auerbach W, Wang XY, Hande MP, Hang H, Wolgemuth DJ, Joyner AL, Lieberman HB.

Mol Cell Biol. 2004 Aug;24(16):7235-48.

18.

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis.

Valenzuela DM, Murphy AJ, Frendewey D, Gale NW, Economides AN, Auerbach W, Poueymirou WT, Adams NC, Rojas J, Yasenchak J, Chernomorsky R, Boucher M, Elsasser AL, Esau L, Zheng J, Griffiths JA, Wang X, Su H, Xue Y, Dominguez MG, Noguera I, Torres R, Macdonald LE, Stewart AF, DeChiara TM, Yancopoulos GD.

Nat Biotechnol. 2003 Jun;21(6):652-9. Epub 2003 May 5.

PMID:
12730667
19.

A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse development.

Nakashima M, Tanese N, Ito M, Auerbach W, Bai C, Furukawa T, Toyono T, Akamine A, Joyner AL.

Mech Dev. 2002 Nov;119(1):21-34.

20.

Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway.

Bai CB, Auerbach W, Lee JS, Stephen D, Joyner AL.

Development. 2002 Oct;129(20):4753-61.

21.

The upstream ectoderm enhancer in Pax6 has an important role in lens induction.

Dimanlig PV, Faber SC, Auerbach W, Makarenkova HP, Lang RA.

Development. 2001 Nov;128(22):4415-24.

22.

The HD mutation causes progressive lethal neurological disease in mice expressing reduced levels of huntingtin.

Auerbach W, Hurlbert MS, Hilditch-Maguire P, Wadghiri YZ, Wheeler VC, Cohen SI, Joyner AL, MacDonald ME, Turnbull DH.

Hum Mol Genet. 2001 Oct 15;10(22):2515-23.

PMID:
11709539
23.

Establishment and chimera analysis of 129/SvEv- and C57BL/6-derived mouse embryonic stem cell lines.

Auerbach W, Dunmore JH, Fairchild-Huntress V, Fang Q, Auerbach AB, Huszar D, Joyner AL.

Biotechniques. 2000 Nov;29(5):1024-8, 1030, 1032.

24.

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.

Wheeler VC, White JK, Gutekunst CA, Vrbanac V, Weaver M, Li XJ, Li SH, Yi H, Vonsattel JP, Gusella JF, Hersch S, Auerbach W, Joyner AL, MacDonald ME.

Hum Mol Genet. 2000 Mar 1;9(4):503-13.

PMID:
10699173
25.

Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse.

Wheeler VC, Auerbach W, White JK, Srinidhi J, Auerbach A, Ryan A, Duyao MP, Vrbanac V, Weaver M, Gusella JF, Joyner AL, MacDonald ME.

Hum Mol Genet. 1999 Jan;8(1):115-22.

PMID:
9887339
26.

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion.

White JK, Auerbach W, Duyao MP, Vonsattel JP, Gusella JF, Joyner AL, MacDonald ME.

Nat Genet. 1997 Dec;17(4):404-10.

PMID:
9398841
27.

Profound effects on vascular development caused by perturbations during organogenesis.

Auerbach R, Auerbach W.

Am J Pathol. 1997 Nov;151(5):1183-6. Review. No abstract available.

28.

Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia.

Chen M, Tomkins DJ, Auerbach W, McKerlie C, Youssoufian H, Liu L, Gan O, Carreau M, Auerbach A, Groves T, Guidos CJ, Freedman MH, Cross J, Percy DH, Dick JE, Joyner AL, Buchwald M.

Nat Genet. 1996 Apr;12(4):448-51.

PMID:
8630504
29.

Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor.

Rozmahel R, Wilschanski M, Matin A, Plyte S, Oliver M, Auerbach W, Moore A, Forstner J, Durie P, Nadeau J, Bear C, Tsui LC.

Nat Genet. 1996 Mar;12(3):280-7. Erratum in: Nat Genet 1996 May;13(1):129.

PMID:
8589719
30.

Targeted inactivation of the mouse Huntington's disease gene homolog Hdh.

MacDonald ME, Duyao M, Calzonetti T, Auerbach A, Ryan A, Barnes G, White JK, Auerbach W, Vonsattel JP, Gusella JF, Joyner AL.

Cold Spring Harb Symp Quant Biol. 1996;61:627-38. No abstract available.

PMID:
9246489
31.

Angiogenesis inhibition: a review.

Auerbach W, Auerbach R.

Pharmacol Ther. 1994 Sep;63(3):265-311. Review.

PMID:
7530374
32.

Expression of a mutant regulatory subunit of cAMP-dependent protein kinase in the Caco-2 human colonic carcinoma cell line.

Mihajlovic V, Krolczyk AJ, Auerbach W, Buchwald M, Schimmer BP.

Biochem Cell Biol. 1992 Oct-Nov;70(10-11):1039-46.

PMID:
1338409
33.

Regulation of CFTR expression and function during differentiation of intestinal epithelial cells.

Sood R, Bear C, Auerbach W, Reyes E, Jensen T, Kartner N, Riordan JR, Buchwald M.

EMBO J. 1992 Jul;11(7):2487-94.

34.

Assays for angiogenesis: a review.

Auerbach R, Auerbach W, Polakowski I.

Pharmacol Ther. 1991;51(1):1-11. Review.

PMID:
1722898
35.

Regulation of expression of CFTR in human intestinal epithelial cells.

Buchwald M, Sood R, Auerbach W.

Adv Exp Med Biol. 1991;290:241-50; discussion 250-2.

PMID:
1719762
36.
37.

Transformed sweat gland and nasal epithelial cell lines from control and cystic fibrosis individuals.

Buchanan JA, Yeger H, Tabcharani JA, Jensen TJ, Auerbach W, Hanrahan JW, Riodan JR, Buchwald M.

J Cell Sci. 1990 Jan;95 ( Pt 1):109-23.

38.

Non-seminoma testis treated by irradiation at the Rotterdamsch Radio-Therapeutisch Instituut: the risk of metastasis.

van der Werf-Messing BH, Auerbach WM, van Putten WL.

Radiother Oncol. 1984 Aug;2(2):101-5.

PMID:
6505280
39.

Regional differences in the growth of normal and neoplastic cells.

Auerbach R, Auerbach W.

Science. 1982 Jan 8;215(4529):127-34.

PMID:
7053564
40.

Hematology problem.

Auerbach W, Leclair SJ.

Am J Med Technol. 1982 Jan;48(1):47-8. No abstract available.

PMID:
7200324
41.

Primary chondrosarcoma of the ovary.

Talerman A, Auerbach WM, van Meurs AJ.

Histopathology. 1981 May;5(3):319-24.

PMID:
7239452
42.

HISTOCHEMISTRY OF HYDROLYTIC AND OXIDATIVE ENZYMES IN EXPERIMENTAL SKIN CARCINOMA OF THE MOUSE.

AUERBACH WM.

Cancer Res. 1964 Jul;24:937-46. No abstract available.

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