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Items: 22

1.

Genomic Deletion at 10q23 in Prostate Cancer: More Than PTEN Loss?

Poluri RTK, Audet-Walsh É.

Front Oncol. 2018 Jun 29;8:246. doi: 10.3389/fonc.2018.00246. eCollection 2018.

2.

SREBF1 Activity Is Regulated by an AR/mTOR Nuclear Axis in Prostate Cancer.

Audet-Walsh É, Vernier M, Yee T, Laflamme C, Li S, Chen Y, Giguère V.

Mol Cancer Res. 2018 Sep;16(9):1396-1405. doi: 10.1158/1541-7786.MCR-17-0410. Epub 2018 May 21.

PMID:
29784665
3.

Nuclear mTOR acts as a transcriptional integrator of the androgen signaling pathway in prostate cancer.

Audet-Walsh É, Dufour CR, Yee T, Zouanat FZ, Yan M, Kalloghlian G, Vernier M, Caron M, Bourque G, Scarlata E, Hamel L, Brimo F, Aprikian AG, Lapointe J, Chevalier S, Giguère V.

Genes Dev. 2017 Jun 15;31(12):1228-1242. doi: 10.1101/gad.299958.117. Epub 2017 Jul 19.

4.

Inverse Regulation of DHT Synthesis Enzymes 5α-Reductase Types 1 and 2 by the Androgen Receptor in Prostate Cancer.

Audet-Walsh É, Yee T, Tam IS, Giguère V.

Endocrinology. 2017 Apr 1;158(4):1015-1021. doi: 10.1210/en.2016-1926.

PMID:
28324044
5.

Androgen-Dependent Repression of ERRγ Reprograms Metabolism in Prostate Cancer.

Audet-Walsh É, Yee T, McGuirk S, Vernier M, Ouellet C, St-Pierre J, Giguère V.

Cancer Res. 2017 Jan 15;77(2):378-389. doi: 10.1158/0008-5472.CAN-16-1204. Epub 2016 Nov 7.

6.

Correlation between prostate volume and single nucleotide polymorphisms implicated in the steroid pathway.

Cornu JN, Audet-Walsh E, Drouin S, Bigot P, Valeri A, Fournier G, Azzouzi AR, Roupret M, Cormier L, Chanock S, Guillemette C, Cussenot O, Lévesque E, Cancel-Tassin G.

World J Urol. 2017 Feb;35(2):293-298. doi: 10.1007/s00345-016-1869-4. Epub 2016 Jun 8.

PMID:
27277477
7.

Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα.

Yan M, Audet-Walsh É, Manteghi S, Dufour CR, Walker B, Baba M, St-Pierre J, Giguère V, Pause A.

Genes Dev. 2016 May 1;30(9):1034-46. doi: 10.1101/gad.281410.116.

8.

The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer.

Audet-Walsh É, Papadopoli DJ, Gravel SP, Yee T, Bridon G, Caron M, Bourque G, Giguère V, St-Pierre J.

Cell Rep. 2016 Feb 2;14(4):920-931. doi: 10.1016/j.celrep.2015.12.086. Epub 2016 Jan 21.

9.

The multiple universes of estrogen-related receptor α and γ in metabolic control and related diseases.

Audet-Walsh É, Giguére V.

Acta Pharmacol Sin. 2015 Jan;36(1):51-61. doi: 10.1038/aps.2014.121. Epub 2014 Dec 15. Review.

10.

The UGT1 locus is a determinant of prostate cancer recurrence after prostatectomy.

Laverdière I, Flageole C, Audet-Walsh É, Caron P, Fradet Y, Lacombe L, Lévesque É, Guillemette C.

Endocr Relat Cancer. 2015 Feb;22(1):77-85. doi: 10.1530/ERC-14-0423. Epub 2014 Dec 1.

PMID:
25452636
11.

Steroidogenic germline polymorphism predictors of prostate cancer progression in the estradiol pathway.

Lévesque E, Laverdière I, Audet-Walsh E, Caron P, Rouleau M, Fradet Y, Lacombe L, Guillemette C.

Clin Cancer Res. 2014 Jun 1;20(11):2971-83. doi: 10.1158/1078-0432.CCR-13-2567. Epub 2014 Mar 28.

12.

Molecular markers in key steroidogenic pathways, circulating steroid levels, and prostate cancer progression.

Lévesque É, Huang SP, Audet-Walsh É, Lacombe L, Bao BY, Fradet Y, Laverdière I, Rouleau M, Huang CY, Yu CC, Caron P, Guillemette C.

Clin Cancer Res. 2013 Feb 1;19(3):699-709. doi: 10.1158/1078-0432.CCR-12-2812. Epub 2012 Nov 27.

13.

The impact of germline genetic variations in hydroxysteroid (17-beta) dehydrogenases on prostate cancer outcomes after prostatectomy.

Audet-Walsh É, Bellemare J, Lacombe L, Fradet Y, Fradet V, Douville P, Guillemette C, Lévesque É.

Eur Urol. 2012 Jul;62(1):88-96. doi: 10.1016/j.eururo.2011.12.021. Epub 2011 Dec 21.

PMID:
22209174
14.

Deletions of the androgen-metabolizing UGT2B genes have an effect on circulating steroid levels and biochemical recurrence after radical prostatectomy in localized prostate cancer.

Nadeau G, Bellemare J, Audet-Walsh É, Flageole C, Huang SP, Bao BY, Douville P, Caron P, Fradet Y, Lacombe L, Guillemette C, Lévesque E.

J Clin Endocrinol Metab. 2011 Sep;96(9):E1550-7. doi: 10.1210/jc.2011-1049. Epub 2011 Jul 6.

PMID:
21733997
15.

SRD5A polymorphisms and biochemical failure after radical prostatectomy.

Audet-Walsh E, Bellemare J, Nadeau G, Lacombe L, Fradet Y, Fradet V, Huang SP, Bao BY, Douville P, Girard H, Guillemette C, Lévesque E.

Eur Urol. 2011 Dec;60(6):1226-34. doi: 10.1016/j.eururo.2011.06.020. Epub 2011 Jun 29.

PMID:
21715084
16.

Profiling of endogenous estrogens, their precursors, and metabolites in endometrial cancer patients: association with risk and relationship to clinical characteristics.

Audet-Walsh E, Lépine J, Grégoire J, Plante M, Caron P, Têtu B, Ayotte P, Brisson J, Villeneuve L, Bélanger A, Guillemette C.

J Clin Endocrinol Metab. 2011 Feb;96(2):E330-9. doi: 10.1210/jc.2010-2050. Epub 2010 Dec 8.

PMID:
21147881
17.

Circulating estrogens in endometrial cancer cases and their relationship with tissular expression of key estrogen biosynthesis and metabolic pathways.

Lépine J, Audet-Walsh E, Grégoire J, Têtu B, Plante M, Ménard V, Ayotte P, Brisson J, Caron P, Villeneuve L, Bélanger A, Guillemette C.

J Clin Endocrinol Metab. 2010 Jun;95(6):2689-98. doi: 10.1210/jc.2010-2648. Epub 2010 Apr 6.

PMID:
20371658
18.

Profiling endogenous serum estrogen and estrogen-glucuronides by liquid chromatography-tandem mass spectrometry.

Caron P, Audet-Walsh E, Lépine J, Bélanger A, Guillemette C.

Anal Chem. 2009 Dec 15;81(24):10143-8. doi: 10.1021/ac9019126.

PMID:
19916521
19.

Werner's syndrome helicase participates in transcription of phenobarbital-inducible CYP2B genes in rat and mouse liver.

Lachaud AA, Auclair-Vincent S, Massip L, Audet-Walsh E, Lebel M, Anderson A.

Biochem Pharmacol. 2010 Feb 1;79(3):463-70. doi: 10.1016/j.bcp.2009.09.002. Epub 2009 Sep 6.

PMID:
19737542
20.

Glucocorticoids and phenobarbital induce murine CYP2B genes by independent mechanisms.

Audet-Walsh E, Auclair-Vincent S, Anderson A.

Expert Opin Drug Metab Toxicol. 2009 Dec;5(12):1501-11. doi: 10.1517/17425250903234709. Review.

PMID:
19732027
21.

Dexamethasone induction of murine CYP2B genes requires the glucocorticoid receptor.

Audet-Walsh E, Anderson A.

Drug Metab Dispos. 2009 Mar;37(3):580-8. doi: 10.1124/dmd.108.022772. Epub 2008 Dec 1.

22.

The CYP2B2 5' flank contains a complex glucocorticoid response unit.

Audet-Walsh E, Lachaud AA, Anderson A.

Biochem Pharmacol. 2008 Nov 15;76(10):1298-306. doi: 10.1016/j.bcp.2008.08.015. Epub 2008 Aug 22.

PMID:
18782568

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