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Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines.

Patel A, Reuschel EL, Kraynyak KA, Racine T, Park DH, Scott VL, Audet J, Amante D, Wise MC, Keaton AA, Wong G, Villarreal DO, Walters J, Muthumani K, Shedlock DJ, de La Vega MA, Plyler R, Boyer J, Broderick KE, Yan J, Khan AS, Jones S, Bello A, Soule G, Tran KN, He S, Tierney K, Qiu X, Kobinger GP, Sardesai NY, Weiner DB.

J Infect Dis. 2018 Oct 10. doi: 10.1093/infdis/jiy537. [Epub ahead of print]


Fibroblast growth factor receptor 5 (FGFR5) is a co-receptor for FGFR1 that is up-regulated in beta-cells by cytokine-induced inflammation.

Regeenes R, Silva PN, Chang HH, Arany EJ, Shukalyuk AI, Audet J, Kilkenny DM, Rocheleau JV.

J Biol Chem. 2018 Nov 2;293(44):17218-17228. doi: 10.1074/jbc.RA118.003036. Epub 2018 Sep 14.


Intranasal vaccination with ebola virus GP amino acids 258-601 protects mice against lethal challenge.

Su QD, He SH, Yi Y, Qiu F, Lu XX, Jia ZY, Meng QL, Fan XT, Tian RG, Audet J, Qiu XG, Bi SL.

Vaccine. 2018 Oct 1;36(41):6053-6060. doi: 10.1016/j.vaccine.2018.09.003. Epub 2018 Sep 6.


Group cognitive-behavioural therapy for hoarding disorder: Systematic review and meta-analysis.

Bodryzlova Y, Audet JS, Bergeron K, O'Connor K.

Health Soc Care Community. 2018 Jul 23. doi: 10.1111/hsc.12598. [Epub ahead of print] Review.


The interplay between total mercury, methylmercury and dissolved organic matter in fluvial systems: A latitudinal study across Europe.

Bravo AG, Kothawala DN, Attermeyer K, Tessier E, Bodmer P, Ledesma JLJ, Audet J, Casas-Ruiz JP, Catalán N, Cauvy-Fraunié S, Colls M, Deininger A, Evtimova VV, Fonvielle JA, Fuß T, Gilbert P, Herrero Ortega S, Liu L, Mendoza-Lera C, Monteiro J, Mor JR, Nagler M, Niedrist GH, Nydahl AC, Pastor A, Pegg J, Gutmann Roberts C, Pilotto F, Portela AP, González-Quijano CR, Romero F, Rulík M, Amouroux D.

Water Res. 2018 Nov 1;144:172-182. doi: 10.1016/j.watres.2018.06.064. Epub 2018 Jun 29.


Group cognitive-behavioural treatment with long-term follow-up and targeting self-identity for hoarding disorder: An open trial.

O'Connor K, Bodryzlova Y, Audet JS, Koszegi N, Bergeron K, Guitard A.

Clin Psychol Psychother. 2018 Sep;25(5):701-709. doi: 10.1002/cpp.2304. Epub 2018 Jul 1.


Nitrogen and Phosphorus Removal from Agricultural Runoff in Integrated Buffer Zones.

Zak D, Kronvang B, Carstensen MV, Hoffmann CC, Kjeldgaard A, Larsen SE, Audet J, Egemose S, Jorgensen CA, Feuerbach P, Gertz F, Jensen HS.

Environ Sci Technol. 2018 Jun 5;52(11):6508-6517. doi: 10.1021/acs.est.8b01036. Epub 2018 May 15.


Divergence in problem-solving skills is associated with differential expression of glutamate receptors in wild finches.

Audet JN, Kayello L, Ducatez S, Perillo S, Cauchard L, Howard JT, O'Connell LA, Jarvis ED, Lefebvre L.

Sci Adv. 2018 Mar 14;4(3):eaao6369. doi: 10.1126/sciadv.aao6369. eCollection 2018 Mar.


Inductive reasoning and doubt in obsessive compulsive disorder.

O'Connor K, Wilson S, Taillon A, Pélissier MC, Audet JS.

J Behav Ther Exp Psychiatry. 2018 Jun;59:65-71. doi: 10.1016/j.jbtep.2017.11.002. Epub 2017 Nov 7.


De novo PacBio long-read and phased avian genome assemblies correct and add to reference genes generated with intermediate and short reads.

Korlach J, Gedman G, Kingan SB, Chin CS, Howard JT, Audet JN, Cantin L, Jarvis ED.

Gigascience. 2017 Oct 1;6(10):1-16. doi: 10.1093/gigascience/gix085.


Cognitive psychophysiological treatment of bodily-focused repetitive behaviors in adults: An open trial.

O'Connor K, Lavoie M, Desaulniers B, Audet JS.

J Clin Psychol. 2018 Mar;74(3):273-285. doi: 10.1002/jclp.22501. Epub 2017 Aug 16.


The role of feared possible selves in obsessive-compulsive and related disorders: A comparative analysis of a core cognitive self-construct in clinical samples.

Aardema F, Moulding R, Melli G, Radomsky AS, Doron G, Audet JS, Purcell-Lalonde M.

Clin Psychol Psychother. 2018 Jan;25(1):e19-e29. doi: 10.1002/cpp.2121. Epub 2017 Aug 9.


Deep-sequencing of Marburg virus genome during sequential mouse passaging and cell-culture adaptation reveals extensive changes over time.

Wei H, Audet J, Wong G, He S, Huang X, Cutts T, Theriault S, Xu B, Kobinger G, Qiu X.

Sci Rep. 2017 Jun 13;7(1):3390. doi: 10.1038/s41598-017-03318-3.


DNA vaccination protects mice against Zika virus-induced damage to the testes.

Griffin BD, Muthumani K, Warner BM, Majer A, Hagan M, Audet J, Stein DR, Ranadheera C, Racine T, De La Vega MA, Piret J, Kucas S, Tran KN, Frost KL, De Graff C, Soule G, Scharikow L, Scott J, McTavish G, Smid V, Park YK, Maslow JN, Sardesai NY, Kim JJ, Yao XJ, Bello A, Lindsay R, Boivin G, Booth SA, Kobasa D, Embury-Hyatt C, Safronetz D, Weiner DB, Kobinger GP.

Nat Commun. 2017 Jun 7;8:15743. doi: 10.1038/ncomms15743.


Augmentation of Psychotherapy through Alternative Preconscious Priming: A Case Series Exploring Effects on Residual Symptoms.

Zidani M, Audet JS, Borgeat F, Aardema F, O'Connor KP, Khazaal Y.

Front Psychiatry. 2017 Jan 31;8:8. doi: 10.3389/fpsyt.2017.00008. eCollection 2017.


Over facilitation of unadapted cognitive processes in obsessive compulsive disorder as assessed with the computerized mirror pointing task.

Dulude G, O'Connor K, Audet JS, Bedard MA.

J Psychiatr Res. 2017 Jun;89:73-80. doi: 10.1016/j.jpsychires.2017.01.014. Epub 2017 Jan 31.


Sex-dependent effects of chromogranin B P413L allelic variant as disease modifier in amyotrophic lateral sclerosis.

Ohta Y, Soucy G, Phaneuf D, Audet JN, Gros-Louis F, Rouleau GA, Blasco H, Corcia P, Andersen PM, Nordin F, Yamashita T, Abe K, Julien JP.

Hum Mol Genet. 2016 Nov 1;25(21):4771-4786. doi: 10.1093/hmg/ddw304.


Pathogenicity Comparison Between the Kikwit and Makona Ebola Virus Variants in Rhesus Macaques.

Wong G, Qiu X, de La Vega MA, Fernando L, Wei H, Bello A, Fausther-Bovendo H, Audet J, Kroeker A, Kozak R, Tran K, He S, Tierney K, Soule G, Moffat E, Günther S, Gao GF, Strong J, Embury-Hyatt C, Kobinger G.

J Infect Dis. 2016 Oct 15;214(suppl 3):S281-S289. Epub 2016 Sep 19.


Bajan Birds Pull Strings: Two Wild Antillean Species Enter the Select Club of String-Pullers.

Audet JN, Ducatez S, Lefebvre L.

PLoS One. 2016 Aug 17;11(8):e0156112. doi: 10.1371/journal.pone.0156112. eCollection 2016.


An Adenovirus Vaccine Expressing Ebola Virus Variant Makona Glycoprotein Is Efficacious in Guinea Pigs and Nonhuman Primates.

Wu S, Kroeker A, Wong G, He S, Hou L, Audet J, Wei H, Zhang Z, Fernando L, Soule G, Tran K, Bi S, Zhu T, Yu X, Chen W, Qiu X.

J Infect Dis. 2016 Oct 15;214(suppl 3):S326-S332. Epub 2016 Aug 4. Erratum in: J Infect Dis. 2017 Jan 1;215(1):165.


Ferrets Infected with Bundibugyo Virus or Ebola Virus Recapitulate Important Aspects of Human Filovirus Disease.

Kozak R, He S, Kroeker A, de La Vega MA, Audet J, Wong G, Urfano C, Antonation K, Embury-Hyatt C, Kobinger GP, Qiu X.

J Virol. 2016 Sep 29;90(20):9209-23. doi: 10.1128/JVI.01033-16. Print 2016 Oct 15.


Post-exposure treatment with whole inactivated H5N1 avian influenza virus protects against lethal homologous virus infection in mice.

Hagan M, Ranadheera C, Audet J, Morin J, Leung A, Kobasa D.

Sci Rep. 2016 Jul 12;6:29433. doi: 10.1038/srep29433.


Prophylactic Efficacy of Quercetin 3-β-O-d-Glucoside against Ebola Virus Infection.

Qiu X, Kroeker A, He S, Kozak R, Audet J, Mbikay M, Chrétien M.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5182-8. doi: 10.1128/AAC.00307-16. Print 2016 Sep.


Innovativeness and the effects of urbanization on risk-taking behaviors in wild Barbados birds.

Ducatez S, Audet JN, Rodriguez JR, Kayello L, Lefebvre L.

Anim Cogn. 2017 Jan;20(1):33-42. doi: 10.1007/s10071-016-1007-0. Epub 2016 Jun 10.


The Inference-Based Approach (IBA) to the Treatment of Obsessive-Compulsive Disorder: An Open Trial Across Symptom Subtypes and Treatment-Resistant Cases.

Aardema F, O Connor KP, Delorme ME, Audet JS.

Clin Psychol Psychother. 2017 Mar;24(2):289-301. doi: 10.1002/cpp.2024. Epub 2016 Jun 9.


Two-mAb cocktail protects macaques against the Makona variant of Ebola virus.

Qiu X, Audet J, Lv M, He S, Wong G, Wei H, Luo L, Fernando L, Kroeker A, Fausther Bovendo H, Bello A, Li F, Ye P, Jacobs M, Ippolito G, Saphire EO, Bi S, Shen B, Gao GF, Zeitlin L, Feng J, Zhang B, Kobinger GP.

Sci Transl Med. 2016 Mar 9;8(329):329ra33. doi: 10.1126/scitranslmed.aad9875.


Feeding innovations in a nested phylogeny of Neotropical passerines.

Lefebvre L, Ducatez S, Audet JN.

Philos Trans R Soc Lond B Biol Sci. 2016 Mar 19;371(1690). pii: 20150188. doi: 10.1098/rstb.2015.0188. Review.


Quantitative serology assays for determination of antibody responses to Ebola virus glycoprotein and matrix protein in nonhuman primates and humans.

Vu H, Shulenin S, Grolla A, Audet J, He S, Kobinger G, Unfer RC, Warfield KL, Aman MJ, Holtsberg FW.

Antiviral Res. 2016 Feb;126:55-61. doi: 10.1016/j.antiviral.2015.11.012. Epub 2015 Dec 8.


Ebola viral load at diagnosis associates with patient outcome and outbreak evolution.

de La Vega MA, Caleo G, Audet J, Qiu X, Kozak RA, Brooks JI, Kern S, Wolz A, Sprecher A, Greig J, Lokuge K, Kargbo DK, Kargbo B, Di Caro A, Grolla A, Kobasa D, Strong JE, Ippolito G, Van Herp M, Kobinger GP.

J Clin Invest. 2015 Dec;125(12):4421-8. doi: 10.1172/JCI83162. Epub 2015 Nov 9.


Development and Characterization of a Guinea Pig-Adapted Sudan Virus.

Wong G, He S, Wei H, Kroeker A, Audet J, Leung A, Cutts T, Graham J, Kobasa D, Embury-Hyatt C, Kobinger GP, Qiu X.

J Virol. 2015 Oct 21;90(1):392-9. doi: 10.1128/JVI.02331-15. Print 2016 Jan 1.


Eutrophication effects on greenhouse gas fluxes from shallow-lake mesocosms override those of climate warming.

Davidson TA, Audet J, Svenning JC, Lauridsen TL, Søndergaard M, Landkildehus F, Larsen SE, Jeppesen E.

Glob Chang Biol. 2015 Dec;21(12):4449-63. doi: 10.1111/gcb.13062.


Core and region-enriched networks of behaviorally regulated genes and the singing genome.

Whitney O, Pfenning AR, Howard JT, Blatti CA, Liu F, Ward JM, Wang R, Audet JN, Kellis M, Mukherjee S, Sinha S, Hartemink AJ, West AE, Jarvis ED.

Science. 2014 Dec 12;346(6215):1256780. doi: 10.1126/science.1256780.


Convergent differential regulation of SLIT-ROBO axon guidance genes in the brains of vocal learners.

Wang R, Chen CC, Hara E, Rivas MV, Roulhac PL, Howard JT, Chakraborty M, Audet JN, Jarvis ED.

J Comp Neurol. 2015 Apr 15;523(6):892-906. doi: 10.1002/cne.23719. Epub 2014 Dec 30.


Immune evasion in ebolavirus infections.

Audet J, Kobinger GP.

Viral Immunol. 2015 Feb;28(1):10-8. doi: 10.1089/vim.2014.0066. Review.


Problem-solving and learning in Carib grackles: individuals show a consistent speed-accuracy trade-off.

Ducatez S, Audet JN, Lefebvre L.

Anim Cogn. 2015 Mar;18(2):485-96. doi: 10.1007/s10071-014-0817-1. Epub 2014 Nov 9.


Molecular characterization of the monoclonal antibodies composing ZMAb: a protective cocktail against Ebola virus.

Audet J, Wong G, Wang H, Lu G, Gao GF, Kobinger G, Qiu X.

Sci Rep. 2014 Nov 6;4:6881. doi: 10.1038/srep06881.


A Single Dose Respiratory Recombinant Adenovirus-Based Vaccine Provides Long-Term Protection for Non-Human Primates from Lethal Ebola Infection.

Choi JH, Jonsson-Schmunk K, Qiu X, Shedlock DJ, Strong J, Xu JX, Michie KL, Audet J, Fernando L, Myers MJ, Weiner D, Bajrovic I, Tran LQ, Wong G, Bello A, Kobinger GP, Schafer SC, Croyle MA.

Mol Pharm. 2015 Aug 3;12(8):2712-31. doi: 10.1021/mp500646d. Epub 2014 Nov 14.


Morphological and molecular sexing of the monochromatic Barbados bullfinch, Loxigilla barbadensis.

Audet JN, Ducatez S, Lefebvre L.

Zoolog Sci. 2014 Oct;31(10):687-91. doi: 10.2108/zs140025.


Immunization with vesicular stomatitis virus vaccine expressing the Ebola glycoprotein provides sustained long-term protection in rodents.

Wong G, Audet J, Fernando L, Fausther-Bovendo H, Alimonti JB, Kobinger GP, Qiu X.

Vaccine. 2014 Sep 29;32(43):5722-9. doi: 10.1016/j.vaccine.2014.08.028. Epub 2014 Aug 27.


Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp.

Qiu X, Wong G, Audet J, Bello A, Fernando L, Alimonti JB, Fausther-Bovendo H, Wei H, Aviles J, Hiatt E, Johnson A, Morton J, Swope K, Bohorov O, Bohorova N, Goodman C, Kim D, Pauly MH, Velasco J, Pettitt J, Olinger GG, Whaley K, Xu B, Strong JE, Zeitlin L, Kobinger GP.

Nature. 2014 Oct 2;514(7520):47-53. doi: 10.1038/nature13777. Epub 2014 Aug 29.


Establishment and characterization of a lethal mouse model for the Angola strain of Marburg virus.

Qiu X, Wong G, Audet J, Cutts T, Niu Y, Booth S, Kobinger GP.

J Virol. 2014 Nov;88(21):12703-14. doi: 10.1128/JVI.01643-14. Epub 2014 Aug 20.


Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb.

Qiu X, Audet J, Wong G, Fernando L, Bello A, Pillet S, Alimonti JB, Kobinger GP.

Sci Rep. 2013 Nov 28;3:3365. doi: 10.1038/srep03365.


mAbs and Ad-vectored IFN-α therapy rescue Ebola-infected nonhuman primates when administered after the detection of viremia and symptoms.

Qiu X, Wong G, Fernando L, Audet J, Bello A, Strong J, Alimonti JB, Kobinger GP.

Sci Transl Med. 2013 Oct 16;5(207):207ra143. doi: 10.1126/scitranslmed.3006605.


Automated digital microfluidic platform for magnetic-particle-based immunoassays with optimization by design of experiments.

Choi K, Ng AH, Fobel R, Chang-Yen DA, Yarnell LE, Pearson EL, Oleksak CM, Fischer AT, Luoma RP, Robinson JM, Audet J, Wheeler AR.

Anal Chem. 2013 Oct 15;85(20):9638-46. doi: 10.1021/ac401847x. Epub 2013 Aug 26.


Independent appearance of an innovative feeding behaviour in Antillean bullfinches.

Ducatez S, Audet JN, Lefebvre L.

Anim Cogn. 2013 May;16(3):525-9. doi: 10.1007/s10071-013-0612-4. Epub 2013 Feb 14.


Abnormal regenerative responses and impaired axonal outgrowth after nerve crush in TDP-43 transgenic mouse models of amyotrophic lateral sclerosis.

Swarup V, Audet JN, Phaneuf D, Kriz J, Julien JP.

J Neurosci. 2012 Dec 12;32(50):18186-95. doi: 10.1523/JNEUROSCI.2267-12.2012.


Standardization of the filovirus plaque assay for use in preclinical studies.

Shurtleff AC, Biggins JE, Keeney AE, Zumbrun EE, Bloomfield HA, Kuehne A, Audet JL, Alfson KJ, Griffiths A, Olinger GG, Bavari S; Filovirus Animal Nonclinical Group (FANG) Assay Working Group.

Viruses. 2012 Dec 6;4(12):3511-30. doi: 10.3390/v4123511. Review.


Biochemical measurements on single erythroid progenitor cells shed light on the combinatorial regulation of red blood cell production.

Wang W, Akbarian V, Audet J.

Mol Biosyst. 2013 Feb 2;9(2):234-45. doi: 10.1039/c2mb25348h. Epub 2012 Nov 21.


Pragmatic inference, not semantic competence, guides 3-year-olds' interpretation of unknown number words.

Brooks N, Audet J, Barner D.

Dev Psychol. 2013 Jun;49(6):1066-75. doi: 10.1037/a0029384. Epub 2012 Jul 23.


Successful treatment of ebola virus-infected cynomolgus macaques with monoclonal antibodies.

Qiu X, Audet J, Wong G, Pillet S, Bello A, Cabral T, Strong JE, Plummer F, Corbett CR, Alimonti JB, Kobinger GP.

Sci Transl Med. 2012 Jun 13;4(138):138ra81. doi: 10.1126/scitranslmed.3003876.

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