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Items: 35

1.

Identification of novel inhibitors of auxin-induced Ca2+ signaling via a plant-based chemical screen.

De Vriese K, Himschoot E, Dunser K, Nguyen L, Drozdzecki A, Costa A, Nowack MK, Kleine-Vehn J, Audenaert D, Beeckman T, Vanneste S.

Plant Physiol. 2019 Feb 8. pii: pp.01393.2018. doi: 10.1104/pp.18.01393. [Epub ahead of print]

2.

Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors.

Mishev K, Lu Q, Denoo B, Peurois F, Dejonghe W, Hullaert J, De Rycke R, Boeren S, Bretou M, De Munck S, Sharma I, Goodman K, Kalinowska K, Storme V, Nguyen LSL, Drozdzecki A, Martins S, Nerinckx W, Audenaert D, Vert G, Madder A, Otegui MS, Isono E, Savvides SN, Annaert W, De Vries S, Cherfils J, Winne J, Russinova E.

Plant Cell. 2018 Oct;30(10):2573-2593. doi: 10.1105/tpc.18.00145. Epub 2018 Jul 17.

PMID:
30018157
3.

Multi-Parametric Screening in Arabidopsis thaliana Seedlings.

Nguyen L, Drozdzecki A, Goossens V, De Rybel B, Beeckman T, Audenaert D.

Methods Mol Biol. 2018;1795:1-7. doi: 10.1007/978-1-4939-7874-8_1.

PMID:
29846914
4.

Mitochondrial Defects Confer Tolerance against Cellulose Deficiency.

Hu Z, Vanderhaeghen R, Cools T, Wang Y, De Clercq I, Leroux O, Nguyen L, Belt K, Millar AH, Audenaert D, Hilson P, Small I, Mouille G, Vernhettes S, Van Breusegem F, Whelan J, Höfte H, De Veylder L.

Plant Cell. 2016 Sep;28(9):2276-2290. doi: 10.1105/tpc.16.00540. Epub 2016 Aug 19.

5.

Chemical Genetics Uncovers Novel Inhibitors of Lignification, Including p-Iodobenzoic Acid Targeting CINNAMATE-4-HYDROXYLASE.

Van de Wouwer D, Vanholme R, Decou R, Goeminne G, Audenaert D, Nguyen L, Höfer R, Pesquet E, Vanholme B, Boerjan W.

Plant Physiol. 2016 Sep;172(1):198-220. doi: 10.1104/pp.16.00430. Epub 2016 Aug 2.

6.

CEP5 and XIP1/CEPR1 regulate lateral root initiation in Arabidopsis.

Roberts I, Smith S, Stes E, De Rybel B, Staes A, van de Cotte B, Njo MF, Dedeyne L, Demol H, Lavenus J, Audenaert D, Gevaert K, Beeckman T, De Smet I.

J Exp Bot. 2016 Aug;67(16):4889-99. doi: 10.1093/jxb/erw231. Epub 2016 Jun 13.

7.

Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidification.

Dejonghe W, Kuenen S, Mylle E, Vasileva M, Keech O, Viotti C, Swerts J, Fendrych M, Ortiz-Morea FA, Mishev K, Delang S, Scholl S, Zarza X, Heilmann M, Kourelis J, Kasprowicz J, Nguyen le SL, Drozdzecki A, Van Houtte I, Szatmári AM, Majda M, Baisa G, Bednarek SY, Robert S, Audenaert D, Testerink C, Munnik T, Van Damme D, Heilmann I, Schumacher K, Winne J, Friml J, Verstreken P, Russinova E.

Nat Commun. 2016 Jun 8;7:11710. doi: 10.1038/ncomms11710.

8.

Cyclic programmed cell death stimulates hormone signaling and root development in Arabidopsis.

Xuan W, Band LR, Kumpf RP, Van Damme D, Parizot B, De Rop G, Opdenacker D, Möller BK, Skorzinski N, Njo MF, De Rybel B, Audenaert D, Nowack MK, Vanneste S, Beeckman T.

Science. 2016 Jan 22;351(6271):384-7. doi: 10.1126/science.aad2776.

9.

Activation of auxin signalling counteracts photorespiratory H2O2-dependent cell death.

Kerchev P, Mühlenbock P, Denecker J, Morreel K, Hoeberichts FA, Van Der Kelen K, Vandorpe M, Nguyen L, Audenaert D, Van Breusegem F.

Plant Cell Environ. 2015 Feb;38(2):253-65.

10.

Root Cap-Derived Auxin Pre-patterns the Longitudinal Axis of the Arabidopsis Root.

Xuan W, Audenaert D, Parizot B, Möller BK, Njo MF, De Rybel B, De Rop G, Van Isterdael G, Mähönen AP, Vanneste S, Beeckman T.

Curr Biol. 2015 May 18;25(10):1381-8. doi: 10.1016/j.cub.2015.03.046. Epub 2015 May 7.

11.

Mitochondrial perturbation negatively affects auxin signaling.

Kerchev PI, De Clercq I, Denecker J, Mühlenbock P, Kumpf R, Nguyen L, Audenaert D, Dejonghe W, Van Breusegem F.

Mol Plant. 2014 Jul;7(7):1138-50. doi: 10.1093/mp/ssu071. Epub 2014 Jun 5.

12.

TR-DB: an open-access database of compounds affecting the ethylene-induced triple response in Arabidopsis.

Hu Y, Callebert P, Vandemoortel I, Nguyen L, Audenaert D, Verschraegen L, Vandenbussche F, Van Der Straeten D.

Plant Physiol Biochem. 2014 Feb;75:128-37. doi: 10.1016/j.plaphy.2013.12.008. Epub 2014 Jan 4.

PMID:
24441765
13.

Synthetic molecules: helping to unravel plant signal transduction.

Xuan W, Murphy E, Beeckman T, Audenaert D, De Smet I.

J Chem Biol. 2013 Mar 3;6(2):43-50. doi: 10.1007/s12154-013-0091-8. eCollection 2013 Mar 3. Review.

14.

A secreted peptide acts on BIN2-mediated phosphorylation of ARFs to potentiate auxin response during lateral root development.

Cho H, Ryu H, Rho S, Hill K, Smith S, Audenaert D, Park J, Han S, Beeckman T, Bennett MJ, Hwang D, De Smet I, Hwang I.

Nat Cell Biol. 2014 Jan;16(1):66-76. doi: 10.1038/ncb2893. Epub 2013 Dec 22.

PMID:
24362628
15.

Fully automated compound screening in Arabidopsis thaliana seedlings.

Audenaert D, Nguyen L, De Rybel B, Beeckman T.

Methods Mol Biol. 2014;1056:3-9. doi: 10.1007/978-1-62703-592-7_1.

PMID:
24306857
16.

Small-molecule screens to study lateral root development.

Audenaert D, De Rybel B, Nguyen L, Beeckman T.

Methods Mol Biol. 2013;959:189-95. doi: 10.1007/978-1-62703-221-6_12.

PMID:
23299676
17.

A role for the root cap in root branching revealed by the non-auxin probe naxillin.

De Rybel B, Audenaert D, Xuan W, Overvoorde P, Strader LC, Kepinski S, Hoye R, Brisbois R, Parizot B, Vanneste S, Liu X, Gilday A, Graham IA, Nguyen L, Jansen L, Njo MF, Inzé D, Bartel B, Beeckman T.

Nat Chem Biol. 2012 Sep;8(9):798-805. doi: 10.1038/nchembio.1044. Epub 2012 Aug 12.

18.

Tackling drought stress: receptor-like kinases present new approaches.

Marshall A, Aalen RB, Audenaert D, Beeckman T, Broadley MR, Butenko MA, Caño-Delgado AI, de Vries S, Dresselhaus T, Felix G, Graham NS, Foulkes J, Granier C, Greb T, Grossniklaus U, Hammond JP, Heidstra R, Hodgman C, Hothorn M, Inzé D, Ostergaard L, Russinova E, Simon R, Skirycz A, Stahl Y, Zipfel C, De Smet I.

Plant Cell. 2012 Jun;24(6):2262-78. doi: 10.1105/tpc.112.096677. Epub 2012 Jun 12. Review.

19.

Small-molecule dissection of brassinosteroid signaling.

Codreanu MC, Audenaert D, Nguyen L, Beeckman T, Russinova E.

Methods Mol Biol. 2012;876:95-106. doi: 10.1007/978-1-61779-809-2_7.

PMID:
22576088
20.

KCNQ2 encephalopathy: emerging phenotype of a neonatal epileptic encephalopathy.

Weckhuysen S, Mandelstam S, Suls A, Audenaert D, Deconinck T, Claes LR, Deprez L, Smets K, Hristova D, Yordanova I, Jordanova A, Ceulemans B, Jansen A, Hasaerts D, Roelens F, Lagae L, Yendle S, Stanley T, Heron SE, Mulley JC, Berkovic SF, Scheffer IE, de Jonghe P.

Ann Neurol. 2012 Jan;71(1):15-25. doi: 10.1002/ana.22644.

PMID:
22275249
21.

A novel aux/IAA28 signaling cascade activates GATA23-dependent specification of lateral root founder cell identity.

De Rybel B, Vassileva V, Parizot B, Demeulenaere M, Grunewald W, Audenaert D, Van Campenhout J, Overvoorde P, Jansen L, Vanneste S, Möller B, Wilson M, Holman T, Van Isterdael G, Brunoud G, Vuylsteke M, Vernoux T, De Veylder L, Inzé D, Weijers D, Bennett MJ, Beeckman T.

Curr Biol. 2010 Oct 12;20(19):1697-706. doi: 10.1016/j.cub.2010.09.007. Epub 2010 Sep 30.

22.

The past, present, and future of chemical biology in auxin research.

De Rybel B, Audenaert D, Beeckman T, Kepinski S.

ACS Chem Biol. 2009 Dec 18;4(12):987-98. doi: 10.1021/cb9001624. Review.

PMID:
19736989
23.

Chemical inhibition of a subset of Arabidopsis thaliana GSK3-like kinases activates brassinosteroid signaling.

De Rybel B, Audenaert D, Vert G, Rozhon W, Mayerhofer J, Peelman F, Coutuer S, Denayer T, Jansen L, Nguyen L, Vanhoutte I, Beemster GT, Vleminckx K, Jonak C, Chory J, Inzé D, Russinova E, Beeckman T.

Chem Biol. 2009 Jun 26;16(6):594-604. doi: 10.1016/j.chembiol.2009.04.008.

24.

Familial occipitotemporal lobe epilepsy and migraine with visual aura: linkage to chromosome 9q.

Deprez L, Peeters K, Van Paesschen W, Claeys KG, Claes LR, Suls A, Audenaert D, Van Dyck T, Goossens D, Del-Favero J, De Jonghe P.

Neurology. 2007 Jun 5;68(23):1995-2002. Epub 2007 Apr 25.

PMID:
17460155
25.

Auxin-dependent regulation of lateral root positioning in the basal meristem of Arabidopsis.

De Smet I, Tetsumura T, De Rybel B, Frei dit Frey N, Laplaze L, Casimiro I, Swarup R, Naudts M, Vanneste S, Audenaert D, Inzé D, Bennett MJ, Beeckman T.

Development. 2007 Feb;134(4):681-90. Epub 2007 Jan 10.

26.

A novel GABRG2 mutation associated with febrile seizures.

Audenaert D, Schwartz E, Claeys KG, Claes L, Deprez L, Suls A, Van Dyck T, Lagae L, Van Broeckhoven C, Macdonald RL, De Jonghe P.

Neurology. 2006 Aug 22;67(4):687-90.

PMID:
16924025
27.

Microdeletions involving the SCN1A gene may be common in SCN1A-mutation-negative SMEI patients.

Suls A, Claeys KG, Goossens D, Harding B, Van Luijk R, Scheers S, Deprez L, Audenaert D, Van Dyck T, Beeckmans S, Smouts I, Ceulemans B, Lagae L, Buyse G, Barisic N, Misson JP, Wauters J, Del-Favero J, De Jonghe P, Claes LR.

Hum Mutat. 2006 Sep;27(9):914-20.

PMID:
16865694
28.

Genes and loci involved in febrile seizures and related epilepsy syndromes.

Audenaert D, Van Broeckhoven C, De Jonghe P.

Hum Mutat. 2006 May;27(5):391-401. Review.

PMID:
16550559
29.

Genome-wide linkage of febrile seizures and epilepsy to the FEB4 locus at 5q14.3-q23.1 and no MASS1 mutation.

Deprez L, Claes LR, Claeys KG, Audenaert D, Van Dyck T, Goossens D, Van Paesschen W, Del-Favero J, Van Broeckhoven C, De Jonghe P.

Hum Genet. 2006 Jan;118(5):618-25. Epub 2005 Nov 5.

PMID:
16273391
30.

A novel susceptibility locus at 2p24 for generalised epilepsy with febrile seizures plus.

Audenaert D, Claes L, Claeys KG, Deprez L, Van Dyck T, Goossens D, Del-Favero J, Van Paesschen W, Van Broeckhoven C, De Jonghe P.

J Med Genet. 2005 Dec;42(12):947-52. Epub 2005 Apr 12.

31.

De novo KCNQ2 mutations in patients with benign neonatal seizures.

Claes LR, Ceulemans B, Audenaert D, Deprez L, Jansen A, Hasaerts D, Weckx S, Claeys KG, Del-Favero J, Van Broeckhoven C, De Jonghe P.

Neurology. 2004 Dec 14;63(11):2155-8.

PMID:
15596769
32.

Novel locus on chromosome 12q22-q23.3 responsible for familial temporal lobe epilepsy associated with febrile seizures.

Claes L, Audenaert D, Deprez L, Van Paesschen W, Depondt C, Goossens D, Del-Favero J, Van Broeckhoven C, De Jonghe P.

J Med Genet. 2004 Sep;41(9):710-4. No abstract available.

33.

A deletion in SCN1B is associated with febrile seizures and early-onset absence epilepsy.

Audenaert D, Claes L, Ceulemans B, Löfgren A, Van Broeckhoven C, De Jonghe P.

Neurology. 2003 Sep 23;61(6):854-6.

PMID:
14504340
34.

De novo SCN1A mutations are a major cause of severe myoclonic epilepsy of infancy.

Claes L, Ceulemans B, Audenaert D, Smets K, Löfgren A, Del-Favero J, Ala-Mello S, Basel-Vanagaite L, Plecko B, Raskin S, Thiry P, Wolf NI, Van Broeckhoven C, De Jonghe P.

Hum Mutat. 2003 Jun;21(6):615-21.

PMID:
12754708
35.

Mutation analysis of 4 candidate genes for hereditary neuralgic amyotrophy (HNA).

Meuleman J, Kuhlenbäumer G, Audenaert D, Hünermund G, Hor H, Young P, Stögbauer F, Ringelstein EB, Van Broeckhoven C, De Jonghe P, Timmerman V.

Hum Genet. 2001 May;108(5):390-3.

PMID:
11409865

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