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Items: 13


MEN1309/OBT076, a First-In-Class Antibody-Drug Conjugate Targeting CD205 in Solid Tumors.

Merlino G, Fiascarelli A, Bigioni M, Bressan A, Carrisi C, Bellarosa D, Salerno M, Bugianesi R, Manno R, Bernadó Morales C, Arribas J, Dusek RL, Ackroyd JE, Pham PH, Awdew R, Aud D, Trang M, Lynch CM, Terrett J, Wilson KE, Rohlff C, Manzini S, Pellacani A, Binaschi M.

Mol Cancer Ther. 2019 Sep;18(9):1533-1543. doi: 10.1158/1535-7163.MCT-18-0624. Epub 2019 Jun 21.


Targeting CD157 in AML using a novel, Fc-engineered antibody construct.

Krupka C, Lichtenegger FS, Köhnke T, Bögeholz J, Bücklein V, Roiss M, Altmann T, Do TU, Dusek R, Wilson K, Bisht A, Terrett J, Aud D, Pombo-Villar E, Rohlff C, Hiddemann W, Subklewe M.

Oncotarget. 2017 May 30;8(22):35707-35717. doi: 10.18632/oncotarget.16060.


Pamapimod, a novel p38 mitogen-activated protein kinase inhibitor: preclinical analysis of efficacy and selectivity.

Hill RJ, Dabbagh K, Phippard D, Li C, Suttmann RT, Welch M, Papp E, Song KW, Chang KC, Leaffer D, Kim YN, Roberts RT, Zabka TS, Aud D, Dal Porto J, Manning AM, Peng SL, Goldstein DM, Wong BR.

J Pharmacol Exp Ther. 2008 Dec;327(3):610-9. doi: 10.1124/jpet.108.139006. Epub 2008 Sep 5.


The candidate lupus susceptibility gene Ifi202a is largely dispensable for B-cell function.

Gubbels Bupp MR, Li M, Pashine A, Aud D, Peng SL.

Rheumatology (Oxford). 2008 Jan;47(1):103-4. Epub 2007 Nov 22. No abstract available.


Genetic mapping in mice identifies DMBT1 as a candidate modifier of mammary tumors and breast cancer risk.

Blackburn AC, Hill LZ, Roberts AL, Wang J, Aud D, Jung J, Nikolcheva T, Allard J, Peltz G, Otis CN, Cao QJ, Ricketts RS, Naber SP, Mollenhauer J, Poustka A, Malamud D, Jerry DJ.

Am J Pathol. 2007 Jun;170(6):2030-41.


Mechanisms of disease: Transcription factors in inflammatory arthritis.

Aud D, Peng SL.

Nat Clin Pract Rheumatol. 2006 Aug;2(8):434-42. Review.


Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members.

Patel AC, Morton JD, Kim EY, Alevy Y, Swanson S, Tucker J, Huang G, Agapov E, Phillips TE, Fuentes ME, Iglesias A, Aud D, Allard JD, Dabbagh K, Peltz G, Holtzman MJ.

Physiol Genomics. 2006 May 16;25(3):502-13. Epub 2006 Mar 28.


A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes.

Noble JA, White AM, Lazzeroni LC, Valdes AM, Mirel DB, Reynolds R, Grupe A, Aud D, Peltz G, Erlich HA.

Diabetes. 2003 Jun;52(6):1579-82.


In silico mapping of complex disease-related traits in mice.

Grupe A, Germer S, Usuka J, Aud D, Belknap JK, Klein RF, Ahluwalia MK, Higuchi R, Peltz G.

Science. 2001 Jun 8;292(5523):1915-8.


Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma.

Karp CL, Grupe A, Schadt E, Ewart SL, Keane-Moore M, Cuomo PJ, Köhl J, Wahl L, Kuperman D, Germer S, Aud D, Peltz G, Wills-Karp M.

Nat Immunol. 2000 Sep;1(3):221-6.


Interleukin-6 is required for a protective immune response to systemic Escherichia coli infection.

Dalrymple SA, Slattery R, Aud DM, Krishna M, Lucian LA, Murray R.

Infect Immun. 1996 Aug;64(8):3231-5.


Interleukin-6-deficient mice are highly susceptible to Listeria monocytogenes infection: correlation with inefficient neutrophilia.

Dalrymple SA, Lucian LA, Slattery R, McNeil T, Aud DM, Fuchino S, Lee F, Murray R.

Infect Immun. 1995 Jun;63(6):2262-8.


Mice deficient for the IL-3/GM-CSF/IL-5 beta c receptor exhibit lung pathology and impaired immune response, while beta IL3 receptor-deficient mice are normal.

Nishinakamura R, Nakayama N, Hirabayashi Y, Inoue T, Aud D, McNeil T, Azuma S, Yoshida S, Toyoda Y, Arai K, et al.

Immunity. 1995 Mar;2(3):211-22.

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