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Items: 1 to 50 of 68

1.

Interplay between coding and exonic splicing regulatory sequences.

Fontrodona N, Aubé F, Claude JB, Polvèche H, Lemaire S, Tranchevent LC, Modolo L, Mortreux F, Bourgeois CF, Auboeuf D.

Genome Res. 2019 May;29(5):711-722. doi: 10.1101/gr.241315.118. Epub 2019 Apr 8.

PMID:
30962178
2.

Pluripotent Stem Cell-Based Drug Screening Reveals Cardiac Glycosides as Modulators of Myotonic Dystrophy Type 1.

Maury Y, Poydenot P, Brinon B, Lesueur L, Gide J, Roquevière S, Côme J, Polvèche H, Auboeuf D, Alexandre Denis J, Pietu G, Furling D, Lechuga M, Baghdoyan S, Peschanski M, Martinat C.

iScience. 2019 Jan 25;11:258-271. doi: 10.1016/j.isci.2018.12.019. Epub 2018 Dec 27.

3.

The RNA helicase DDX17 controls the transcriptional activity of REST and the expression of proneural microRNAs in neuronal differentiation.

Lambert MP, Terrone S, Giraud G, Benoit-Pilven C, Cluet D, Combaret V, Mortreux F, Auboeuf D, Bourgeois CF.

Nucleic Acids Res. 2018 Sep 6;46(15):7686-7700. doi: 10.1093/nar/gky545.

4.

Complementarity of assembly-first and mapping-first approaches for alternative splicing annotation and differential analysis from RNAseq data.

Benoit-Pilven C, Marchet C, Chautard E, Lima L, Lambert MP, Sacomoto G, Rey A, Cologne A, Terrone S, Dulaurier L, Claude JB, Bourgeois CF, Auboeuf D, Lacroix V.

Sci Rep. 2018 Mar 9;8(1):4307. doi: 10.1038/s41598-018-21770-7.

5.

Alternative mRNA processing sites decrease genetic variability while increasing functional diversity.

Auboeuf D.

Transcription. 2018;9(2):75-87. doi: 10.1080/21541264.2017.1373891. Epub 2017 Nov 3. Review.

6.

The RNA helicase DDX5 is a reprogramming roadblock.

Bourgeois CF, Auboeuf D.

Stem Cell Investig. 2017 Sep 27;4:79. doi: 10.21037/sci.2017.09.04. eCollection 2017. No abstract available.

7.

Genome evolution is driven by gene expression-generated biophysical constraints through RNA-directed genetic variation: A hypothesis.

Auboeuf D.

Bioessays. 2017 Oct;39(10). doi: 10.1002/bies.201700069. Epub 2017 Sep 8. Review.

PMID:
28885715
8.

Translational reprogramming of colorectal cancer cells induced by 5-fluorouracil through a miRNA-dependent mechanism.

Bash-Imam Z, Thérizols G, Vincent A, Lafôrets F, Polay Espinoza M, Pion N, Macari F, Pannequin J, David A, Saurin JC, Mertani HC, Textoris J, Auboeuf D, Catez F, Dalla Venezia N, Dutertre M, Marcel V, Diaz JJ.

Oncotarget. 2017 Jul 11;8(28):46219-46233. doi: 10.18632/oncotarget.17597.

9.

Identification of protein features encoded by alternative exons using Exon Ontology.

Tranchevent LC, Aubé F, Dulaurier L, Benoit-Pilven C, Rey A, Poret A, Chautard E, Mortada H, Desmet FO, Chakrama FZ, Moreno-Garcia MA, Goillot E, Janczarski S, Mortreux F, Bourgeois CF, Auboeuf D.

Genome Res. 2017 Jun;27(6):1087-1097. doi: 10.1101/gr.212696.116. Epub 2017 Apr 18.

10.

TET2 exon 2 skipping is an independent favorable prognostic factor for cytogenetically normal acute myelogenous leukemia (AML): TET2 exon 2 skipping in AML.

Mohamed AM, Balsat M, Koering C, Maucort-Boulch D, Boissel N, Payen-Gay L, Cheok M, Mortada H, Auboeuf D, Pinatel C, El-Hamri M, Tigaud I, Hayette S, Dumontet C, Cros E, Flandrin-Gresta P, Nibourel O, Preudhomme C, Thomas X, Nicolini FE, Solly F, Guyotat D, Campos L, Michallet M, Ceraulo A, Mortreux F, Wattel E.

Leuk Res. 2017 May;56:21-28. doi: 10.1016/j.leukres.2017.01.012. Epub 2017 Jan 16.

PMID:
28167452
11.

Putative RNA-Directed Adaptive Mutations in Cancer Evolution.

Auboeuf D.

Transcription. 2016 Aug 10:0. [Epub ahead of print]

12.

Nucleosome eviction in mitosis assists condensin loading and chromosome condensation.

Toselli-Mollereau E, Robellet X, Fauque L, Lemaire S, Schiklenk C, Klein C, Hocquet C, Legros P, N'Guyen L, Mouillard L, Chautard E, Auboeuf D, Haering CH, Bernard P.

EMBO J. 2016 Jul 15;35(14):1565-81. doi: 10.15252/embj.201592849. Epub 2016 Jun 6.

13.

The multiple functions of RNA helicases as drivers and regulators of gene expression.

Bourgeois CF, Mortreux F, Auboeuf D.

Nat Rev Mol Cell Biol. 2016 Jul;17(7):426-38. doi: 10.1038/nrm.2016.50. Epub 2016 Jun 2. Review.

PMID:
27251421
14.

The proto-oncogenic protein TAL1 controls TGF-β1 signaling through interaction with SMAD3.

Terme JM, Lemaire S, Auboeuf D, Mocquet V, Jalinot P.

Biochim Open. 2016 May 14;2:69-78. doi: 10.1016/j.biopen.2016.05.001. eCollection 2016 Jun.

15.

Candidate gene prioritization with Endeavour.

Tranchevent LC, Ardeshirdavani A, ElShal S, Alcaide D, Aerts J, Auboeuf D, Moreau Y.

Nucleic Acids Res. 2016 Jul 8;44(W1):W117-21. doi: 10.1093/nar/gkw365. Epub 2016 Apr 30.

16.

Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy.

Freyermuth F, Rau F, Kokunai Y, Linke T, Sellier C, Nakamori M, Kino Y, Arandel L, Jollet A, Thibault C, Philipps M, Vicaire S, Jost B, Udd B, Day JW, Duboc D, Wahbi K, Matsumura T, Fujimura H, Mochizuki H, Deryckere F, Kimura T, Nukina N, Ishiura S, Lacroix V, Campan-Fournier A, Navratil V, Chautard E, Auboeuf D, Horie M, Imoto K, Lee KY, Swanson MS, de Munain AL, Inada S, Itoh H, Nakazawa K, Ashihara T, Wang E, Zimmer T, Furling D, Takahashi MP, Charlet-Berguerand N.

Nat Commun. 2016 Apr 11;7:11067. doi: 10.1038/ncomms11067.

17.

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents.

Merlevede J, Droin N, Qin T, Meldi K, Yoshida K, Morabito M, Chautard E, Auboeuf D, Fenaux P, Braun T, Itzykson R, de Botton S, Quesnel B, Commes T, Jourdan E, Vainchenker W, Bernard O, Pata-Merci N, Solier S, Gayevskiy V, Dinger ME, Cowley MJ, Selimoglu-Buet D, Meyer V, Artiguenave F, Deleuze JF, Preudhomme C, Stratton MR, Alexandrov LB, Padron E, Ogawa S, Koscielny S, Figueroa M, Solary E.

Nat Commun. 2016 Feb 24;7:10767. doi: 10.1038/ncomms10767.

18.

In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin.

Laustriat D, Gide J, Barrault L, Chautard E, Benoit C, Auboeuf D, Boland A, Battail C, Artiguenave F, Deleuze JF, Bénit P, Rustin P, Franc S, Charpentier G, Furling D, Bassez G, Nissan X, Martinat C, Peschanski M, Baghdoyan S.

Mol Ther Nucleic Acids. 2015 Nov 3;4:e262. doi: 10.1038/mtna.2015.35.

19.

Oncogene- and drug resistance-associated alternative exon usage in acute myeloid leukemia (AML).

Mohamed AM, Balsat M, Thenoz M, Koering C, Payen-Gay L, Cheok M, Mortada H, Auboeuf D, Pinatel C, El-Hamri M, Dumontet C, Cros E, Flandrin-Gresta P, Nibourel O, Preudhomme C, Michallet M, Thomas X, Nicolini F, Solly F, Guyotat D, Campos L, Wattel E, Mortreux F.

Oncotarget. 2016 Jan 19;7(3):2889-909. doi: 10.18632/oncotarget.3898.

20.

HTLV-1-infected CD4+ T-cells display alternative exon usages that culminate in adult T-cell leukemia.

Thénoz M, Vernin C, Mortada H, Karam M, Pinatel C, Gessain A, Webb TR, Auboeuf D, Wattel E, Mortreux F.

Retrovirology. 2014 Dec 18;11:119. doi: 10.1186/s12977-014-0119-3.

21.

RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation.

Dardenne E, Polay Espinoza M, Fattet L, Germann S, Lambert MP, Neil H, Zonta E, Mortada H, Gratadou L, Deygas M, Chakrama FZ, Samaan S, Desmet FO, Tranchevent LC, Dutertre M, Rimokh R, Bourgeois CF, Auboeuf D.

Cell Rep. 2014 Jun 26;7(6):1900-13. doi: 10.1016/j.celrep.2014.05.010. Epub 2014 Jun 6.

22.

A recently evolved class of alternative 3'-terminal exons involved in cell cycle regulation by topoisomerase inhibitors.

Dutertre M, Chakrama FZ, Combe E, Desmet FO, Mortada H, Polay Espinoza M, Gratadou L, Auboeuf D.

Nat Commun. 2014 Feb 28;5:3395. doi: 10.1038/ncomms4395.

23.

Endothelial, epithelial, and fibroblast cells exhibit specific splicing programs independently of their tissue of origin.

Mallinjoud P, Villemin JP, Mortada H, Polay Espinoza M, Desmet FO, Samaan S, Chautard E, Tranchevent LC, Auboeuf D.

Genome Res. 2014 Mar;24(3):511-21. doi: 10.1101/gr.162933.113. Epub 2013 Dec 4.

24.

The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways.

Samaan S, Tranchevent LC, Dardenne E, Polay Espinoza M, Zonta E, Germann S, Gratadou L, Dutertre M, Auboeuf D.

Nucleic Acids Res. 2014 Feb;42(4):2197-207. doi: 10.1093/nar/gkt1216. Epub 2013 Nov 25.

25.

hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.

Chapat C, Kolytcheff C, Le Romancer M, Auboeuf D, De La Grange P, Chettab K, Sentis S, Corbo L.

EMBO J. 2013 Mar 6;32(5):688-700. doi: 10.1038/emboj.2013.11. Epub 2013 Feb 5.

26.

The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA export.

Zonta E, Bittencourt D, Samaan S, Germann S, Dutertre M, Auboeuf D.

Nucleic Acids Res. 2013 Jan 7;41(1):554-64. doi: 10.1093/nar/gks1046. Epub 2012 Nov 11.

27.

TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs.

Ballarino M, Jobert L, Dembélé D, de la Grange P, Auboeuf D, Tora L.

Oncogene. 2013 Sep 26;32(39):4646-55. doi: 10.1038/onc.2012.490. Epub 2012 Nov 5.

PMID:
23128393
28.

Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness.

Dardenne E, Pierredon S, Driouch K, Gratadou L, Lacroix-Triki M, Espinoza MP, Zonta E, Germann S, Mortada H, Villemin JP, Dutertre M, Lidereau R, Vagner S, Auboeuf D.

Nat Struct Mol Biol. 2012 Nov;19(11):1139-46. doi: 10.1038/nsmb.2390. Epub 2012 Sep 30.

PMID:
23022728
29.

Alternative splicing and cancer.

Auboeuf D, Carmo-Fonseca M, Valcarcel J, Biamonti G.

J Nucleic Acids. 2012;2012:363809. doi: 10.1155/2012/363809. Epub 2012 May 20. No abstract available.

30.

Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor.

Germann S, Gratadou L, Zonta E, Dardenne E, Gaudineau B, Fougère M, Samaan S, Dutertre M, Jauliac S, Auboeuf D.

Oncogene. 2012 Oct 18;31(42):4536-49. doi: 10.1038/onc.2011.618. Epub 2012 Jan 23.

PMID:
22266867
31.

Splicing programs and cancer.

Germann S, Gratadou L, Dutertre M, Auboeuf D.

J Nucleic Acids. 2012;2012:269570. doi: 10.1155/2012/269570. Epub 2011 Oct 24.

32.

Analysis of co-transcriptional RNA processing by RNA-ChIP assay.

Bittencourt D, Auboeuf D.

Methods Mol Biol. 2012;809:563-77. doi: 10.1007/978-1-61779-376-9_36.

PMID:
22113300
33.

The emerging role of pre-messenger RNA splicing in stress responses: sending alternative messages and silent messengers.

Dutertre M, Sanchez G, Barbier J, Corcos L, Auboeuf D.

RNA Biol. 2011 Sep-Oct;8(5):740-7. doi: 10.4161/rna.8.5.16016. Epub 2011 Jun 29. Review.

PMID:
21712650
34.

Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy.

Rau F, Freyermuth F, Fugier C, Villemin JP, Fischer MC, Jost B, Dembele D, Gourdon G, Nicole A, Duboc D, Wahbi K, Day JW, Fujimura H, Takahashi MP, Auboeuf D, Dreumont N, Furling D, Charlet-Berguerand N.

Nat Struct Mol Biol. 2011 Jun 19;18(7):840-5. doi: 10.1038/nsmb.2067.

PMID:
21685920
35.

Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation.

Schmidt U, Basyuk E, Robert MC, Yoshida M, Villemin JP, Auboeuf D, Aitken S, Bertrand E.

J Cell Biol. 2011 May 30;193(5):819-29. doi: 10.1083/jcb.201009012.

36.

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy.

Fugier C, Klein AF, Hammer C, Vassilopoulos S, Ivarsson Y, Toussaint A, Tosch V, Vignaud A, Ferry A, Messaddeq N, Kokunai Y, Tsuburaya R, de la Grange P, Dembele D, Francois V, Precigout G, Boulade-Ladame C, Hummel MC, Lopez de Munain A, Sergeant N, Laquerrière A, Thibault C, Deryckere F, Auboeuf D, Garcia L, Zimmermann P, Udd B, Schoser B, Takahashi MP, Nishino I, Bassez G, Laporte J, Furling D, Charlet-Berguerand N.

Nat Med. 2011 Jun;17(6):720-5. doi: 10.1038/nm.2374. Epub 2011 May 29.

PMID:
21623381
37.

Outcome of children treated with haematopoietic-stem cell transplantations from donors expressing the rare C77G variant of the PTPRC (CD45) gene.

Samaan S, Guérin-El Khourouj V, Auboeuf D, Peltier L, Pédron B, Ouachée-Chardin M, Gourgouillon N, Baruchel A, Dalle JH, Sterkers G.

Br J Haematol. 2011 Apr;153(1):47-57. doi: 10.1111/j.1365-2141.2011.08568.x. Epub 2011 Feb 17.

PMID:
21323873
38.

Cotranscriptional exon skipping in the genotoxic stress response.

Dutertre M, Sanchez G, De Cian MC, Barbier J, Dardenne E, Gratadou L, Dujardin G, Le Jossic-Corcos C, Corcos L, Auboeuf D.

Nat Struct Mol Biol. 2010 Nov;17(11):1358-66. doi: 10.1038/nsmb.1912. Epub 2010 Oct 24.

PMID:
20972445
39.

Alternative splicing and breast cancer.

Dutertre M, Vagner S, Auboeuf D.

RNA Biol. 2010 Jul-Aug;7(4):403-11. Epub 2010 Jul 1. Review.

PMID:
20622514
40.

Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer.

Dutertre M, Gratadou L, Dardenne E, Germann S, Samaan S, Lidereau R, Driouch K, de la Grange P, Auboeuf D.

Cancer Res. 2010 May 1;70(9):3760-70. doi: 10.1158/0008-5472.CAN-09-3988. Epub 2010 Apr 20.

41.

Splicing factor and exon profiling across human tissues.

de la Grange P, Gratadou L, Delord M, Dutertre M, Auboeuf D.

Nucleic Acids Res. 2010 May;38(9):2825-38. doi: 10.1093/nar/gkq008. Epub 2010 Jan 27.

42.

Exon-based clustering of murine breast tumor transcriptomes reveals alternative exons whose expression is associated with metastasis.

Dutertre M, Lacroix-Triki M, Driouch K, de la Grange P, Gratadou L, Beck S, Millevoi S, Tazi J, Lidereau R, Vagner S, Auboeuf D.

Cancer Res. 2010 Feb 1;70(3):896-905. doi: 10.1158/0008-5472.CAN-09-2703. Epub 2010 Jan 26.

43.

NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene.

Fougère M, Gaudineau B, Barbier J, Guaddachi F, Feugeas JP, Auboeuf D, Jauliac S.

Oncogene. 2010 Apr 15;29(15):2292-301. doi: 10.1038/onc.2009.499. Epub 2010 Jan 25.

PMID:
20101218
44.

Widespread estrogen-dependent repression of micrornas involved in breast tumor cell growth.

Maillot G, Lacroix-Triki M, Pierredon S, Gratadou L, Schmidt S, Bénès V, Roché H, Dalenc F, Auboeuf D, Millevoi S, Vagner S.

Cancer Res. 2009 Nov 1;69(21):8332-40. doi: 10.1158/0008-5472.CAN-09-2206. Epub 2009 Oct 13.

45.

Coupled alteration of transcription and splicing by a single oncogene: boosting the effect on cyclin D1 activity.

Sanchez G, Delattre O, Auboeuf D, Dutertre M.

Cell Cycle. 2008 Aug;7(15):2299-305. Epub 2008 Jun 17. Review.

PMID:
18677114
46.

Cotranscriptional splicing potentiates the mRNA production from a subset of estradiol-stimulated genes.

Bittencourt D, Dutertre M, Sanchez G, Barbier J, Gratadou L, Auboeuf D.

Mol Cell Biol. 2008 Sep;28(18):5811-24. doi: 10.1128/MCB.02231-07. Epub 2008 Jul 21.

47.

Nonsense-mediated mRNA decay impacts MSI-driven carcinogenesis and anti-tumor immunity in colorectal cancers.

El-Bchiri J, Guilloux A, Dartigues P, Loire E, Mercier D, Buhard O, Sobhani I, de la Grange P, Auboeuf D, Praz F, Fléjou JF, Duval A.

PLoS One. 2008 Jul 9;3(7):e2583. doi: 10.1371/journal.pone.0002583.

48.

Alteration of cyclin D1 transcript elongation by a mutated transcription factor up-regulates the oncogenic D1b splice isoform in cancer.

Sanchez G, Bittencourt D, Laud K, Barbier J, Delattre O, Auboeuf D, Dutertre M.

Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6004-9. doi: 10.1073/pnas.0710748105. Epub 2008 Apr 14.

49.

Regulation of H-ras splice variant expression by cross talk between the p53 and nonsense-mediated mRNA decay pathways.

Barbier J, Dutertre M, Bittencourt D, Sanchez G, Gratadou L, de la Grange P, Auboeuf D.

Mol Cell Biol. 2007 Oct;27(20):7315-33. Epub 2007 Aug 20.

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