Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 51


Conformational changes and catalytic inefficiency associated with Mot1-mediated TBP-DNA dissociation.

Heiss G, Ploetz E, Voith von Voithenberg L, Viswanathan R, Glaser S, Schluesche P, Madhira S, Meisterernst M, Auble DT, Lamb DC.

Nucleic Acids Res. 2019 Apr 8;47(6):2793-2806. doi: 10.1093/nar/gky1322.


Histone H3 lysine 4 methylation signature associated with human undernutrition.

Uchiyama R, Kupkova K, Shetty SJ, Linford AS, Pray-Grant MG, Wagar LE, Davis MM, Haque R, Gaultier A, Mayo MW, Grant PA, Petri WA Jr, Bekiranov S, Auble DT.

Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):E11264-E11273. doi: 10.1073/pnas.1722125115. Epub 2018 Nov 12.


Crystal structure of the full Swi2/Snf2 remodeler Mot1 in the resting state.

Butryn A, Woike S, Shetty SJ, Auble DT, Hopfner KP.

Elife. 2018 Oct 5;7. pii: e37774. doi: 10.7554/eLife.37774.


An Improved Method for Measuring Chromatin-binding Dynamics Using Time-dependent Formaldehyde Crosslinking.

Hoffman EA, Zaidi H, Shetty SJ, Bekiranov S, Auble DT.

Bio Protoc. 2018 Feb 20;8(4). pii: e2905. doi: 10.21769/bioprotoc.2905.


Second-generation method for analysis of chromatin binding with formaldehyde-cross-linking kinetics.

Zaidi H, Hoffman EA, Shetty SJ, Bekiranov S, Auble DT.

J Biol Chem. 2017 Nov 24;292(47):19338-19355. doi: 10.1074/jbc.M117.796441. Epub 2017 Sep 26.


Transcriptomes of six mutants in the Sen1 pathway reveal combinatorial control of transcription termination across the Saccharomyces cerevisiae genome.

Chen X, Poorey K, Carver MN, Müller U, Bekiranov S, Auble DT, Brow DA.

PLoS Genet. 2017 Jun 30;13(6):e1006863. doi: 10.1371/journal.pgen.1006863. eCollection 2017 Jun.


RNA synthesis is associated with multiple TBP-chromatin binding events.

Zaidi HA, Auble DT, Bekiranov S.

Sci Rep. 2017 Jan 4;7:39631. doi: 10.1038/srep39631.


Molecular Mechanism of Mot1, a TATA-binding Protein (TBP)-DNA Dissociating Enzyme.

Viswanathan R, True JD, Auble DT.

J Biol Chem. 2016 Jul 22;291(30):15714-26. doi: 10.1074/jbc.M116.730366. Epub 2016 Jun 2.


The Modifier of Transcription 1 (Mot1) ATPase and Spt16 Histone Chaperone Co-regulate Transcription through Preinitiation Complex Assembly and Nucleosome Organization.

True JD, Muldoon JJ, Carver MN, Poorey K, Shetty SJ, Bekiranov S, Auble DT.

J Biol Chem. 2016 Jul 15;291(29):15307-19. doi: 10.1074/jbc.M116.735134. Epub 2016 May 16.


Formaldehyde crosslinking: a tool for the study of chromatin complexes.

Hoffman EA, Frey BL, Smith LM, Auble DT.

J Biol Chem. 2015 Oct 30;290(44):26404-11. doi: 10.1074/jbc.R115.651679. Epub 2015 Sep 9. Review.


Structural basis for recognition and remodeling of the TBP:DNA:NC2 complex by Mot1.

Butryn A, Schuller JM, Stoehr G, Runge-Wollmann P, Förster F, Auble DT, Hopfner KP.

Elife. 2015 Aug 10;4. doi: 10.7554/eLife.07432.


Analysis of chromatin binding dynamics using the crosslinking kinetics (CLK) method.

Viswanathan R, Hoffman EA, Shetty SJ, Bekiranov S, Auble DT.

Methods. 2014 Dec;70(2-3):97-107. doi: 10.1016/j.ymeth.2014.10.029. Epub 2014 Nov 1.


Measuring chromatin interaction dynamics on the second time scale at single-copy genes.

Poorey K, Viswanathan R, Carver MN, Karpova TS, Cirimotich SM, McNally JG, Bekiranov S, Auble DT.

Science. 2013 Oct 18;342(6156):369-72. doi: 10.1126/science.1242369. Epub 2013 Oct 3.


Two-step mechanism for modifier of transcription 1 (Mot1) enzyme-catalyzed displacement of TATA-binding protein (TBP) from DNA.

Moyle-Heyrman G, Viswanathan R, Widom J, Auble DT.

J Biol Chem. 2012 Mar 16;287(12):9002-12. doi: 10.1074/jbc.M111.333484. Epub 2012 Feb 1.


Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP.

Wollmann P, Cui S, Viswanathan R, Berninghausen O, Wells MN, Moldt M, Witte G, Butryn A, Wendler P, Beckmann R, Auble DT, Hopfner KP.

Nature. 2011 Jul 6;475(7356):403-7. doi: 10.1038/nature10215.


An evolutionarily 'young' lysine residue in histone H3 attenuates transcriptional output in Saccharomyces cerevisiae.

Hyland EM, Molina H, Poorey K, Jie C, Xie Z, Dai J, Qian J, Bekiranov S, Auble DT, Pandey A, Boeke JD.

Genes Dev. 2011 Jun 15;25(12):1306-19. doi: 10.1101/gad.2050311.


One small step for Mot1; one giant leap for other Swi2/Snf2 enzymes?

Viswanathan R, Auble DT.

Biochim Biophys Acta. 2011 Sep;1809(9):488-96. doi: 10.1016/j.bbagrm.2011.05.012. Epub 2011 May 30. Review.


The Rad23 ubiquitin receptor, the proteasome and functional specificity in transcriptional control.

Wade SL, Auble DT.

Transcription. 2010 Jul-Aug;1(1):22-6. doi: 10.4161/trns.1.1.12201.


RNA synthesis precision is regulated by preinitiation complex turnover.

Poorey K, Sprouse RO, Wells MN, Viswanathan R, Bekiranov S, Auble DT.

Genome Res. 2010 Dec;20(12):1679-88. doi: 10.1101/gr.109504.110. Epub 2010 Sep 20.


The Snf1 kinase and proteasome-associated Rad23 regulate UV-responsive gene expression.

Wade SL, Poorey K, Bekiranov S, Auble DT.

EMBO J. 2009 Oct 7;28(19):2919-31. doi: 10.1038/emboj.2009.229. Epub 2009 Aug 13.


TATA-binding protein variants that bypass the requirement for Mot1 in vivo.

Sprouse RO, Wells MN, Auble DT.

J Biol Chem. 2009 Feb 13;284(7):4525-35. doi: 10.1074/jbc.M808951200. Epub 2008 Dec 21.


Novel influenza virus NS1 antagonists block replication and restore innate immune function.

Basu D, Walkiewicz MP, Frieman M, Baric RS, Auble DT, Engel DA.

J Virol. 2009 Feb;83(4):1881-91. doi: 10.1128/JVI.01805-08. Epub 2008 Dec 3.


The dynamic personality of TATA-binding protein.

Auble DT.

Trends Biochem Sci. 2009 Feb;34(2):49-52. doi: 10.1016/j.tibs.2008.10.008. Epub 2008 Nov 27.


Regulation of TATA-binding protein dynamics in living yeast cells.

Sprouse RO, Karpova TS, Mueller F, Dasgupta A, McNally JG, Auble DT.

Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13304-8. doi: 10.1073/pnas.0801901105. Epub 2008 Sep 2.


Function and structural organization of Mot1 bound to a natural target promoter.

Sprouse RO, Shcherbakova I, Cheng H, Jamison E, Brenowitz M, Auble DT.

J Biol Chem. 2008 Sep 5;283(36):24935-48. doi: 10.1074/jbc.M803749200. Epub 2008 Jul 7.


Regulation of rRNA synthesis by TATA-binding protein-associated factor Mot1.

Dasgupta A, Sprouse RO, French S, Aprikian P, Hontz R, Juedes SA, Smith JS, Beyer AL, Auble DT.

Mol Cell Biol. 2007 Apr;27(8):2886-96. Epub 2007 Feb 12.


Snf2/Swi2-related ATPase Mot1 drives displacement of TATA-binding protein by gripping DNA.

Sprouse RO, Brenowitz M, Auble DT.

EMBO J. 2006 Apr 5;25(7):1492-504. Epub 2006 Mar 16.


Mot1-mediated control of transcription complex assembly and activity.

Dasgupta A, Juedes SA, Sprouse RO, Auble DT.

EMBO J. 2005 May 4;24(9):1717-29. Epub 2005 Apr 7.


The NEF4 complex regulates Rad4 levels and utilizes Snf2/Swi2-related ATPase activity for nucleotide excision repair.

Ramsey KL, Smith JJ, Dasgupta A, Maqani N, Grant P, Auble DT.

Mol Cell Biol. 2004 Jul;24(14):6362-78.


Sir Antagonist 1 (San1) is a ubiquitin ligase.

Dasgupta A, Ramsey KL, Smith JS, Auble DT.

J Biol Chem. 2004 Jun 25;279(26):26830-8. Epub 2004 Apr 12.


Mot1 regulates the DNA binding activity of free TATA-binding protein in an ATP-dependent manner.

Darst RP, Dasgupta A, Zhu C, Hsu JY, Vroom A, Muldrow T, Auble DT.

J Biol Chem. 2003 Apr 11;278(15):13216-26. Epub 2003 Feb 4.


Mot1 activates and represses transcription by direct, ATPase-dependent mechanisms.

Dasgupta A, Darst RP, Martin KJ, Afshari CA, Auble DT.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2666-71. Erratum in: Proc Natl Acad Sci U S A 2002 Jul 9;99(14):9606.


A new regulatory domain on the TATA-binding protein.

Cang Y, Auble DT, Prelich G.

EMBO J. 1999 Dec 1;18(23):6662-71.


Testing for DNA tracking by MOT1, a SNF2/SWI2 protein family member.

Auble DT, Steggerda SM.

Mol Cell Biol. 1999 Jan;19(1):412-23.


Cloning and biochemical characterization of TAF-172, a human homolog of yeast Mot1.

Chicca JJ 2nd, Auble DT, Pugh BF.

Mol Cell Biol. 1998 Mar;18(3):1701-10.


Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.

Auble DT, Hansen KE, Mueller CG, Lane WS, Thorner J, Hahn S.

Genes Dev. 1994 Aug 15;8(16):1920-34.


An ATP-dependent inhibitor of TBP binding to DNA.

Auble DT, Hahn S.

Genes Dev. 1993 May;7(5):844-56.


Differential regulation of collagenase gene expression by retinoic acid receptors--alpha, beta and gamma.

Pan L, Chamberlain SH, Auble DT, Brinckerhoff CE.

Nucleic Acids Res. 1992 Jun 25;20(12):3105-11.


Transcriptional regulation of matrix metalloproteinase genes: role of AP-1 sequences.

Auble DT, Sirum-Connolly KL, Brinckerhoff CE.

Matrix Suppl. 1992;1:200. No abstract available.


Expression of stromelysin and stromelysin-2 in rabbit and human fibroblasts.

Brinckerhoff CE, Sirum-Connolly KL, Karmilowicz MJ, Auble DT.

Matrix Suppl. 1992;1:165-75.


The AP-1 sequence is necessary but not sufficient for phorbol induction of collagenase in fibroblasts.

Auble DT, Brinckerhoff CE.

Biochemistry. 1991 May 7;30(18):4629-35.


Regulation of collagenase gene expression in synovial fibroblasts.

Brinckerhoff CE, Auble DT.

Ann N Y Acad Sci. 1990;580:355-74. No abstract available.


Supplemental Content

Loading ...
Support Center