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Items: 1 to 50 of 215

1.

ERRα promotes breast cancer cell dissemination to bone by increasing RANK expression in primary breast tumors.

Vargas G, Bouchet M, Bouazza L, Reboul P, Boyault C, Gervais M, Kan C, Benetollo C, Brevet M, Croset M, Mazel M, Cayrefourcq L, Geraci S, Vacher S, Pantano F, Filipits M, Driouch K, Bieche I, Gnant M, Jacot W, Aubin JE, Duterque-Coquillaud M, Alix-Panabières C, Clézardin P, Bonnelye E.

Oncogene. 2019 Feb;38(7):950-964. doi: 10.1038/s41388-018-0579-3. Epub 2018 Nov 26.

2.

Soluble Klotho causes hypomineralization in Klotho-deficient mice.

Minamizaki T, Konishi Y, Sakurai K, Yoshioka H, Aubin JE, Kozai K, Yoshiko Y.

J Endocrinol. 2018 Jun;237(3):285-300. doi: 10.1530/JOE-17-0683. Epub 2018 Apr 9.

PMID:
29632215
3.

Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone.

Fradet A, Bouchet M, Delliaux C, Gervais M, Kan C, Benetollo C, Pantano F, Vargas G, Bouazza L, Croset M, Bala Y, Leroy X, Rosol TJ, Rieusset J, Bellahcène A, Castronovo V, Aubin JE, Clézardin P, Duterque-Coquillaud M, Bonnelye E.

Oncotarget. 2016 Nov 22;7(47):77071-77086. doi: 10.18632/oncotarget.12787.

4.

Bone Shaft Revascularization After Marrow Ablation Is Dramatically Accelerated in BSP-/- Mice, Along With Faster Hematopoietic Recolonization.

Bouleftour W, Granito RN, Vanden-Bossche A, Sabido O, Roche B, Thomas M, Linossier MT, Aubin JE, Lafage-Proust MH, Vico L, Malaval L.

J Cell Physiol. 2017 Sep;232(9):2528-2537. doi: 10.1002/jcp.25630. Epub 2017 Apr 10.

PMID:
27704558
5.

Craniofacial and Dental Defects in the Col1a1Jrt/+ Mouse Model of Osteogenesis Imperfecta.

Eimar H, Tamimi F, Retrouvey JM, Rauch F, Aubin JE, McKee MD.

J Dent Res. 2016 Jul;95(7):761-8. doi: 10.1177/0022034516637045. Epub 2016 Mar 7.

PMID:
26951553
6.

The role of the SIBLING, Bone Sialoprotein in skeletal biology - Contribution of mouse experimental genetics.

Bouleftour W, Juignet L, Bouet G, Granito RN, Vanden-Bossche A, Laroche N, Aubin JE, Lafage-Proust MH, Vico L, Malaval L.

Matrix Biol. 2016 May-Jul;52-54:60-77. doi: 10.1016/j.matbio.2015.12.011. Epub 2016 Jan 5. Review.

PMID:
26763578
7.

Disruption of Src Is Associated with Phenotypes Related to Williams-Beuren Syndrome and Altered Cellular Localization of TFII-I

Sinai L, Ivakine EA, Lam E, Deurloo M, Dida J, Zirngibl RA, Jung C, Aubin JE, Feng ZP, Yeomans J, McInnes RR, Osborne LR, Roder JC.

eNeuro. 2015 Mar 30;2(2). pii: ENEURO.0016-14.2015. doi: 10.1523/ENEURO.0016-14.2015. eCollection 2015 Mar-Apr.

8.

The impairment of osteogenesis in bone sialoprotein (BSP) knockout calvaria cell cultures is cell density dependent.

Bouet G, Bouleftour W, Juignet L, Linossier MT, Thomas M, Vanden-Bossche A, Aubin JE, Vico L, Marchat D, Malaval L.

PLoS One. 2015 Feb 24;10(2):e0117402. doi: 10.1371/journal.pone.0117402. eCollection 2015.

9.

Up-regulation of BMP2/4 signaling increases both osteoblast-specific marker expression and bone marrow adipogenesis in Gja1Jrt/+ stromal cell cultures.

Zappitelli T, Chen F, Aubin JE.

Mol Biol Cell. 2015 Mar 1;26(5):832-42. doi: 10.1091/mbc.E14-06-1136. Epub 2015 Jan 7.

10.

Bone lineage proteins in the entheses of the midfoot in patients with spondyloarthritis.

Pacheco-Tena C, Pérez-Tamayo R, Pineda C, González-Chávez SA, Quiñonez-Flores C, Ugalde Vitelly A, Inman RD, Aubin JE, Vázquez-Mellado J, Burgos-Vargas R.

J Rheumatol. 2015 Apr;42(4):630-7. doi: 10.3899/jrheum.140218. Epub 2014 Dec 15.

PMID:
25512480
11.

Absence of bone sialoprotein (BSP) alters profoundly hematopoiesis and upregulates osteopontin.

Granito RN, Bouleftour W, Sabido O, Lescale C, Thomas M, Aubin JE, Goodhardt M, Vico L, Malaval L.

J Cell Physiol. 2015 Jun;230(6):1342-51. doi: 10.1002/jcp.24877.

PMID:
25502698
12.

Loss of bone sialoprotein leads to impaired endochondral bone development and mineralization.

Holm E, Aubin JE, Hunter GK, Beier F, Goldberg HA.

Bone. 2015 Feb;71:145-54. doi: 10.1016/j.bone.2014.10.007. Epub 2014 Oct 25.

PMID:
25464126
13.

ERRγ is not required for skeletal development but is a RUNX2-dependent negative regulator of postnatal bone formation in male mice.

Cardelli M, Aubin JE.

PLoS One. 2014 Oct 14;9(10):e109592. doi: 10.1371/journal.pone.0109592. eCollection 2014.

14.

Blocking the expression of both bone sialoprotein (BSP) and osteopontin (OPN) impairs the anabolic action of PTH in mouse calvaria bone.

Bouleftour W, Bouet G, Granito RN, Thomas M, Linossier MT, Vanden-Bossche A, Aubin JE, Lafage-Proust MH, Vico L, Malaval L.

J Cell Physiol. 2015 Mar;230(3):568-77. doi: 10.1002/jcp.24772.

PMID:
25160656
15.

The "connexin" between bone cells and skeletal functions.

Zappitelli T, Aubin JE.

J Cell Biochem. 2014 Oct;115(10):1646-58. doi: 10.1002/jcb.24836. Review.

PMID:
24818806
16.

Skeletal development of mice lacking bone sialoprotein (BSP)--impairment of long bone growth and progressive establishment of high trabecular bone mass.

Bouleftour W, Boudiffa M, Wade-Gueye NM, Bouët G, Cardelli M, Laroche N, Vanden-Bossche A, Thomas M, Bonnelye E, Aubin JE, Vico L, Lafage-Proust MH, Malaval L.

PLoS One. 2014 May 9;9(5):e95144. doi: 10.1371/journal.pone.0095144. eCollection 2014.

17.

First mouse model for combined osteogenesis imperfecta and Ehlers-Danlos syndrome.

Chen F, Guo R, Itoh S, Moreno L, Rosenthal E, Zappitelli T, Zirngibl RA, Flenniken A, Cole W, Grynpas M, Osborne LR, Vogel W, Adamson L, Rossant J, Aubin JE.

J Bone Miner Res. 2014 Jun;29(6):1412-23. doi: 10.1002/jbmr.2177.

18.

Cartilage-specific overexpression of ERRγ results in Chondrodysplasia and reduced chondrocyte proliferation.

Cardelli M, Zirngibl RA, Boetto JF, McKenzie KP, Troy TC, Turksen K, Aubin JE.

PLoS One. 2013 Dec 9;8(12):e81511. doi: 10.1371/journal.pone.0081511. eCollection 2013.

19.

Characterization of esophageal defects in the Crouzon mouse model.

Dab S, Sokhi R, Lee JC, Sessle BJ, Aubin JE, Gong SG.

Birth Defects Res A Clin Mol Teratol. 2013 Sep;97(9):578-86. doi: 10.1002/bdra.23172. Epub 2013 Sep 2.

PMID:
23997010
20.

The R740S mutation in the V-ATPase a3 subunit results in osteoclast apoptosis and defective early-stage autophagy.

Ochotny N, Voronov I, Owen C, Aubin JE, Manolson MF.

J Cell Biochem. 2013 Dec;114(12):2823-33. doi: 10.1002/jcb.24630.

PMID:
23908015
21.

EB1 levels are elevated in ascorbic Acid (AA)-stimulated osteoblasts and mediate cell-cell adhesion-induced osteoblast differentiation.

Pustylnik S, Fiorino C, Nabavi N, Zappitelli T, da Silva R, Aubin JE, Harrison RE.

J Biol Chem. 2013 Jul 26;288(30):22096-110. doi: 10.1074/jbc.M113.481515. Epub 2013 Jun 5.

22.

Divergent regulation of the Osteopontin promoter by the estrogen receptor-related receptors is isoform- and cell context dependent.

Zirngibl RA, Chan JS, Aubin JE.

J Cell Biochem. 2013 Oct;114(10):2356-62. doi: 10.1002/jcb.24583.

PMID:
23633411
23.

The G60S connexin 43 mutation activates the osteoblast lineage and results in a resorption-stimulating bone matrix and abrogation of old-age-related bone loss.

Zappitelli T, Chen F, Moreno L, Zirngibl RA, Grynpas M, Henderson JE, Aubin JE.

J Bone Miner Res. 2013 Nov;28(11):2400-13. doi: 10.1002/jbmr.1965.

24.

Both chondroinduction and proliferation account for growth of cartilage nodules in mouse limb bud cultures.

Malko AV, Villagomez M, Aubin JE, Opas M.

Stem Cell Rev Rep. 2013 Apr;9(2):121-31. doi: 10.1007/s12015-013-9434-7.

PMID:
23447083
25.
26.

Deficiency in acellular cementum and periodontal attachment in bsp null mice.

Foster BL, Soenjaya Y, Nociti FH Jr, Holm E, Zerfas PM, Wimer HF, Holdsworth DW, Aubin JE, Hunter GK, Goldberg HA, Somerman MJ.

J Dent Res. 2013 Feb;92(2):166-72. doi: 10.1177/0022034512469026. Epub 2012 Nov 26.

27.

Osteogenesis and expression of the bone marrow niche in endothelial cell-depleted HipOPs.

McKenzie KP, Mayer DC, Aubin JE.

J Cell Biochem. 2013 May;114(5):1066-73. doi: 10.1002/jcb.24446.

PMID:
23161750
28.

Bone marrow-derived HipOP cell population is markedly enriched in osteoprogenitors.

Itoh S, Matsushita K, Ikeda S, Yamamoto Y, Yamauchi Y, Yoshioka S, Yamamoto R, Ebisu S, Hayashi M, Aubin JE.

Int J Mol Sci. 2012;13(8):10229-35. doi: 10.3390/ijms130810229. Epub 2012 Aug 16.

29.

The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis.

Voronov I, Ochotny N, Jaumouillé V, Owen C, Manolson MF, Aubin JE.

J Bone Miner Res. 2013 Jan;28(1):108-18. doi: 10.1002/jbmr.1727.

30.

Absence of bone sialoprotein (BSP) impairs primary bone formation and resorption: the marrow ablation model under PTH challenge.

Wade-Gueye NM, Boudiffa M, Vanden-Bossche A, Laroche N, Aubin JE, Vico L, Lafage-Proust MH, Malaval L.

Bone. 2012 May;50(5):1064-73.

PMID:
22586700
31.

A novel Phex mutation in a new mouse model of hypophosphatemic rickets.

Owen C, Chen F, Flenniken AM, Osborne LR, Ichikawa S, Adamson SL, Rossant J, Aubin JE.

J Cell Biochem. 2012 Jul;113(7):2432-41. doi: 10.1002/jcb.24115.

PMID:
22573557
32.

The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures.

Minamizaki T, Yoshiko Y, Yoshioka H, Kozai K, Aubin JE, Maeda N.

Prostaglandins Other Lipid Mediat. 2012 Mar;97(3-4):97-102. doi: 10.1016/j.prostaglandins.2012.01.001. Epub 2012 Jan 14.

PMID:
22265865
33.

Dual function of ERRα in breast cancer and bone metastasis formation: implication of VEGF and osteoprotegerin.

Fradet A, Sorel H, Bouazza L, Goehrig D, Dépalle B, Bellahcène A, Castronovo V, Follet H, Descotes F, Aubin JE, Clézardin P, Bonnelye E.

Cancer Res. 2011 Sep 1;71(17):5728-38. doi: 10.1158/0008-5472.CAN-11-1431. Epub 2011 Jul 6.

34.

Estrogen receptor-related receptor α regulation by interleukin-1β in prostaglandin E(2)- and cAMP-dependent pathways in osteoarthritic chondrocytes.

Bonnelye E, Reboul P, Duval N, Cardelli M, Aubin JE.

Arthritis Rheum. 2011 Aug;63(8):2374-84. doi: 10.1002/art.30398.

35.

The V-ATPase a3 subunit mutation R740S is dominant negative and results in osteopetrosis in mice.

Ochotny N, Flenniken AM, Owen C, Voronov I, Zirngibl RA, Osborne LR, Henderson JE, Adamson SL, Rossant J, Manolson MF, Aubin JE.

J Bone Miner Res. 2011 Jul;26(7):1484-93. doi: 10.1002/jbmr.355.

36.

Impaired mesenchymal stem cell differentiation and osteoclastogenesis in mice deficient for Igf2-P2 transcripts.

Hardouin SN, Guo R, Romeo PH, Nagy A, Aubin JE.

Development. 2011 Jan;138(2):203-13. doi: 10.1242/dev.054916. Epub 2010 Dec 9.

37.

Mice lacking bone sialoprotein (BSP) lose bone after ovariectomy and display skeletal site-specific response to intermittent PTH treatment.

Wade-Gueye NM, Boudiffa M, Laroche N, Vanden-Bossche A, Fournier C, Aubin JE, Vico L, Lafage-Proust MH, Malaval L.

Endocrinology. 2010 Nov;151(11):5103-13. doi: 10.1210/en.2010-0091. Epub 2010 Sep 15.

PMID:
20844009
38.

Involvement of the orphan nuclear estrogen receptor-related receptor α in osteoclast adhesion and transmigration.

Bonnelye E, Saltel F, Chabadel A, Zirngibl RA, Aubin JE, Jurdic P.

J Mol Endocrinol. 2010 Dec;45(6):365-77. doi: 10.1677/JME-10-0024. Epub 2010 Sep 14.

39.

Bone sialoprotein deficiency impairs osteoclastogenesis and mineral resorption in vitro.

Boudiffa M, Wade-Gueye NM, Guignandon A, Vanden-Bossche A, Sabido O, Aubin JE, Jurdic P, Vico L, Lafage-Proust MH, Malaval L.

J Bone Miner Res. 2010 Dec;25(12):2669-79. doi: 10.1002/jbmr.245. Erratum in: J Bone Miner Res. 2011 Feb;26(2):439.

40.

A subset of osteoblasts expressing high endogenous levels of PPARgamma switches fate to adipocytes in the rat calvaria cell culture model.

Yoshiko Y, Oizumi K, Hasegawa T, Minamizaki T, Tanne K, Maeda N, Aubin JE.

PLoS One. 2010 Jul 26;5(7):e11782. doi: 10.1371/journal.pone.0011782.

41.

1alpha,25-dihydroxyvitamin D3 acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro.

Yamamoto R, Minamizaki T, Yoshiko Y, Yoshioka H, Tanne K, Aubin JE, Maeda N.

J Endocrinol. 2010 Sep;206(3):279-86. doi: 10.1677/JOE-10-0058. Epub 2010 Jun 8.

42.

The missense mutation W290R in Fgfr2 causes developmental defects from aberrant IIIb and IIIc signaling.

Mai S, Wei K, Flenniken A, Adamson SL, Rossant J, Aubin JE, Gong SG.

Dev Dyn. 2010 Jun;239(6):1888-900. doi: 10.1002/dvdy.22314.

43.

The Canadian Institutes of Health Research (CIHR) and its Institute of Musculoskeletal Health and Arthritis (IMHA).

Aubin JE.

J Dent Hyg. 2009 Fall;83(4):155-6. Epub 2009 Nov 2. No abstract available.

PMID:
19909623
44.

Bone sialoprotein, but not osteopontin, deficiency impairs the mineralization of regenerating bone during cortical defect healing.

Monfoulet L, Malaval L, Aubin JE, Rittling SR, Gadeau AP, Fricain JC, Chassande O.

Bone. 2010 Feb;46(2):447-52. doi: 10.1016/j.bone.2009.09.007. Epub 2009 Sep 15.

PMID:
19761880
45.

A novel purification method for multipotential skeletal stem cells.

Itoh S, Aubin JE.

J Cell Biochem. 2009 Oct 1;108(2):368-77. doi: 10.1002/jcb.22262.

PMID:
19591175
46.

Absence of bone sialoprotein (BSP) impairs cortical defect repair in mouse long bone.

Malaval L, Monfoulet L, Fabre T, Pothuaud L, Bareille R, Miraux S, Thiaudiere E, Raffard G, Franconi JM, Lafage-Proust MH, Aubin JE, Vico L, Amédée J.

Bone. 2009 Nov;45(5):853-61. doi: 10.1016/j.bone.2009.06.005. Epub 2009 Jun 12.

PMID:
19524706
47.

Role of the small integrin-binding ligand N-linked glycoprotein (SIBLING), bone sialoprotein (BSP) in bone development and remodeling.

Malaval L, Aubin JE, Vico L.

Osteoporos Int. 2009 Jun;20(6):1077-80. doi: 10.1007/s00198-009-0869-2. No abstract available.

48.

EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures.

Minamizaki T, Yoshiko Y, Kozai K, Aubin JE, Maeda N.

Bone. 2009 Jun;44(6):1177-85. doi: 10.1016/j.bone.2009.02.010. Epub 2009 Feb 21.

PMID:
19233324
49.

Estrogen receptor-related receptor-alpha (ERR-alpha) is dysregulated in inflammatory arthritis.

Bonnelye E, Laurin N, Jurdic P, Hart DA, Aubin JE.

Rheumatology (Oxford). 2008 Dec;47(12):1785-91. doi: 10.1093/rheumatology/ken368. Epub 2008 Oct 16.

PMID:
18927192
50.

The PPARgamma-selective ligand BRL-49653 differentially regulates the fate choices of rat calvaria versus rat bone marrow stromal cell populations.

Hasegawa T, Oizumi K, Yoshiko Y, Tanne K, Maeda N, Aubin JE.

BMC Dev Biol. 2008 Jul 14;8:71. doi: 10.1186/1471-213X-8-71.

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