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Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects.

He Q, Au B, Kulkarni M, Shen Y, Lim KJ, Maimaiti J, Wong CK, Luijten MNH, Chong HC, Lim EH, Rancati G, Sinha I, Fu Z, Wang X, Connolly JE, Crasta KC.

Oncogenesis. 2018 Aug 15;7(8):62. doi: 10.1038/s41389-018-0072-4.


Autophagy Governs Protumorigenic Effects of Mitotic Slippage-induced Senescence.

Jakhar R, Luijten MNH, Wong AXF, Cheng B, Guo K, Neo SP, Au B, Kulkarni M, Lim KJ, Maimaiti J, Chong HC, Lim EH, Tan TBK, Ong KW, Sim Y, Wong JSL, Khoo JBK, Ho JTS, Chua BT, Sinha I, Wang X, Connolly JE, Gunaratne J, Crasta KC.

Mol Cancer Res. 2018 Nov;16(11):1625-1640. doi: 10.1158/1541-7786.MCR-18-0024. Epub 2018 Jul 23.


Toll-Like Receptor 9 Deficiency Breaks Tolerance to RNA-Associated Antigens and Up-Regulates Toll-Like Receptor 7 Protein in Sle1 Mice.

Celhar T, Yasuga H, Lee HY, Zharkova O, Tripathi S, Thornhill SI, Lu HK, Au B, Lim LHK, Thamboo TP, Akira S, Wakeland EK, Connolly JE, Fairhurst AM.

Arthritis Rheumatol. 2018 Oct;70(10):1597-1609. doi: 10.1002/art.40535.


Improving the rates of electronic results acknowledgement at a tertiary eye care centre.

Phua V, Au B, Soh YQ, Husain R.

BMJ Open Qual. 2017 Oct 18;6(2):e000140. doi: 10.1136/bmjoq-2017-000140. eCollection 2017.


Implementation of additional prescribing authorization among oncology pharmacists in Alberta.

Au B, Dersch-Mills D, Ghosh S, Jupp J, Chambers C, Cusano F, Danilak M.

J Oncol Pharm Pract. 2018 Jan 1:1078155217752076. doi: 10.1177/1078155217752076. [Epub ahead of print]


The association between C-reactive protein, Interleukin-6 and depression among older adults in the community: A systematic review and meta-analysis.

Smith KJ, Au B, Ollis L, Schmitz N.

Exp Gerontol. 2018 Feb;102:109-132. doi: 10.1016/j.exger.2017.12.005. Epub 2017 Dec 10. Review.


Sex differences in the prevalence of genetic mutations in FTD and ALS: A meta-analysis.

Curtis AF, Masellis M, Hsiung GR, Moineddin R, Zhang K, Au B, Millett G, Mackenzie I, Rogaeva E, Tierney MC.

Neurology. 2017 Oct 10;89(15):1633-1642. doi: 10.1212/WNL.0000000000004494. Epub 2017 Sep 15. Review.


Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34+ Cells for Correction of Fabry Disease.

Huang J, Khan A, Au BC, Barber DL, López-Vásquez L, Prokopishyn NL, Boutin M, Rothe M, Rip JW, Abaoui M, Nagree MS, Dworski S, Schambach A, Keating A, West ML, Klassen J, Turner PV, Sirrs S, Rupar CA, Auray-Blais C, Foley R, Medin JA.

Mol Ther Methods Clin Dev. 2017 May 12;5:241-258. doi: 10.1016/j.omtm.2017.05.003. eCollection 2017 Jun 16.


What to do when a patient wants to record a patient-physician interaction in the emergency department.

Nolan B, Ackery A, Au B.

CJEM. 2018 May;20(3):471-475. doi: 10.1017/cem.2017.23. Epub 2017 May 16.


Glycosphingolipid storage in Fabry mice extends beyond globotriaosylceramide and is affected by ABCB1 depletion.

Kamani MA, Provençal P, Boutin M, Pacienza N, Fan X, Novak A, Huang TC, Binnington B, Au BC, Auray-Blais C, Lingwood CA, Medin JA.

Future Sci OA. 2016 Oct 13;2(4):FSO147. doi: 10.4155/fsoa-2016-0027. eCollection 2016 Dec.


Effect of comorbidities and medications on frequency of primary care visits among older patients.

Hu T, Dattani ND, Cox KA, Au B, Xu L, Melady D, Jaakkimainen L, Jain R, Charles J.

Can Fam Physician. 2017 Jan;63(1):45-50.


Lymph Node Involvement by a Clear Cell Nodular Hidradenoma-Like Tumor of Uncertain Malignant Potential.

Au B, Sidiropoulos KG, Ghazarian D, Sidiropoulos M.

Am J Dermatopathol. 2017 Dec;39(12):953-954. doi: 10.1097/DAD.0000000000000808. No abstract available.


Meta-analysis of Driving Cessation and Dementia: Does Sex Matter?

Baines N, Au B, Rapoport MJ, Naglie G, Tierney MC.

J Gerontol B Psychol Sci Soc Sci. 2018 Sep 20;73(7):1185-1189. doi: 10.1093/geronb/gbw158.


Comparison of 3 Methods for Maintaining Inter-Fragmentary Compression After Fracture Reduction and Fixation.

Au B, Groundland J, Stoops TK, Santoni BG, Sagi HC.

J Orthop Trauma. 2017 Apr;31(4):210-213. doi: 10.1097/BOT.0000000000000769.


Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML.

Huang J, Liu Y, Au BC, Barber DL, Arruda A, Schambach A, Rothe M, Minden MD, Paige CJ, Medin JA.

Mol Ther Methods Clin Dev. 2016 Dec 7;3:16074. eCollection 2016.


Depressive symptoms, prediabetes, and incident diabetes in older English adults.

Graham E, Au B, Schmitz N.

Int J Geriatr Psychiatry. 2017 Dec;32(12):1450-1458. doi: 10.1002/gps.4634. Epub 2016 Nov 28.


Sex differences in the prevalence and incidence of mild cognitive impairment: A meta-analysis.

Au B, Dale-McGrath S, Tierney MC.

Ageing Res Rev. 2017 May;35:176-199. doi: 10.1016/j.arr.2016.09.005. Epub 2016 Oct 19. Review.


Whole metagenome profiling reveals skin microbiome-dependent susceptibility to atopic dermatitis flare.

Chng KR, Tay AS, Li C, Ng AH, Wang J, Suri BK, Matta SA, McGovern N, Janela B, Wong XF, Sio YY, Au BV, Wilm A, De Sessions PF, Lim TC, Tang MB, Ginhoux F, Connolly JE, Lane EB, Chew FT, Common JE, Nagarajan N.

Nat Microbiol. 2016 Jul 11;1(9):16106. doi: 10.1038/nmicrobiol.2016.106.


Relative distribution of Gb3 isoforms/analogs in NOD/SCID/Fabry mice tissues determined by tandem mass spectrometry.

Provençal P, Boutin M, Dworski S, Au B, Medin JA, Auray-Blais C.

Bioanalysis. 2016 Sep;8(17):1793-807. doi: 10.4155/bio-2016-0116. Epub 2016 Aug 15.


Risk of Diabetes in Older Adults with Co-Occurring Depressive Symptoms and Cardiometabolic Abnormalities: Prospective Analysis from the English Longitudinal Study of Ageing.

Freitas C, Deschênes S, Au B, Smith K, Schmitz N.

PLoS One. 2016 May 26;11(5):e0155741. doi: 10.1371/journal.pone.0155741. eCollection 2016.


Direct Lymph Node Vaccination of Lentivector/Prostate-Specific Antigen is Safe and Generates Tissue-Specific Responses in Rhesus Macaques.

Au BC, Lee CJ, Lopez-Perez O, Foltz W, Felizardo TC, Wang JCM, Huang J, Fan X, Madden M, Goldstein A, Jaffray DA, Moloo B, McCart JA, Medin JA.

Biomedicines. 2016 Feb 19;4(1). pii: E6. doi: 10.3390/biomedicines4010006.


Evaluating lifestyle and health-related characteristics of older adults with co-occurring depressive symptoms and cardiometabolic abnormalities.

Freitas C, Deschênes S, Au B, Smith K, Schmitz N.

Int J Geriatr Psychiatry. 2016 Jan;31(1):66-75. doi: 10.1002/gps.4290. Epub 2015 Apr 1.


Markedly perturbed hematopoiesis in acid ceramidase deficient mice.

Dworski S, Berger A, Furlonger C, Moreau JM, Yoshimitsu M, Trentadue J, Au BC, Paige CJ, Medin JA.

Haematologica. 2015 May;100(5):e162-5. doi: 10.3324/haematol.2014.108530. Epub 2015 Feb 14. No abstract available.


A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis.

Jin P, Andiappan AK, Quek JM, Lee B, Au B, Sio YY, Irwanto A, Schurmann C, Grabe HJ, Suri BK, Matta SA, Westra HJ, Franke L, Esko T, Sun L, Zhang X, Liu H, Zhang F, Larbi A, Xu X, Poidinger M, Liu J, Chew FT, Rotzschke O, Shi L, Wang de Y.

J Allergy Clin Immunol. 2015 Jun;135(6):1486-93.e8. doi: 10.1016/j.jaci.2014.12.1870. Epub 2015 Jan 30.


Reevaluation of the pretransplant assessment of mortality score after allogeneic hematopoietic transplantation.

Au BK, Gooley TA, Armand P, Fang M, Madtes DK, Sorror ML, Boeckh MJ, Gibson CJ, Deeg HJ, Storb R, Appelbaum FR, Chien JW, Martin PJ.

Biol Blood Marrow Transplant. 2015 May;21(5):848-54. doi: 10.1016/j.bbmt.2015.01.011. Epub 2015 Jan 31.


Response to Kawada: C-reactive protein, depressive symptoms and incident diabetes mellitus with special emphasis on physical activity.

Au B, Smith KJ, Gariépy G, Schmitz N.

J Psychosom Res. 2015 Apr;78(4):407-8. doi: 10.1016/j.jpsychores.2015.01.004. Epub 2015 Jan 19. No abstract available.


The longitudinal associations between C-reactive protein and depressive symptoms: evidence from the English Longitudinal Study of Ageing (ELSA).

Au B, Smith KJ, Gariépy G, Schmitz N.

Int J Geriatr Psychiatry. 2015 Sep;30(9):976-84. doi: 10.1002/gps.4250. Epub 2014 Dec 23.


Reduced interferon-α production by dendritic cells in type 1 diabetes does not impair immunity to influenza virus.

Kreuzer D, Nikoopour E, Au BC, Krougly O, Lee-Chan E, Summers KL, Haeryfar SM, Singh B.

Clin Exp Immunol. 2015 Feb;179(2):245-55. doi: 10.1111/cei.12462.


C-reactive protein, depressive symptoms, and risk of diabetes: results from the English Longitudinal Study of Ageing (ELSA).

Au B, Smith KJ, Gariépy G, Schmitz N.

J Psychosom Res. 2014 Sep;77(3):180-6. doi: 10.1016/j.jpsychores.2014.07.012. Epub 2014 Jul 22.


Anti-atherogenic peptide Ep1.B derived from apolipoprotein E induces tolerogenic plasmacytoid dendritic cells.

Bellemore SM, Nikoopour E, Au BC, Krougly O, Lee-Chan E, Haeryfar SM, Singh B.

Clin Exp Immunol. 2014 Sep;177(3):732-42. doi: 10.1111/cei.12370.


Enhanced neutralizing antibody titers and Th1 polarization from a novel Escherichia coli derived pandemic influenza vaccine.

Skibinski DA, Hanson BJ, Lin Y, von Messling V, Jegerlehner A, Tee JB, Chye de H, Wong SK, Ng AA, Lee HY, Au B, Lee BT, Santoso L, Poidinger M, Fairhurst AM, Matter A, Bachmann MF, Saudan P, Connolly JE.

PLoS One. 2013 Oct 18;8(10):e76571. doi: 10.1371/journal.pone.0076571. eCollection 2013.


Cytokine analysis of aqueous humor in HIV patients with cytomegalovirus retinitis.

Iyer JV, Connolly J, Agrawal R, Yeo TK, Lee B, Au B, Teoh SC.

Cytokine. 2013 Nov;64(2):541-7. doi: 10.1016/j.cyto.2013.08.006. Epub 2013 Sep 3.


Engineering lentiviral vectors for modulation of dendritic cell apoptotic pathways.

Wang JC, Felizardo TC, Au BC, Fowler DH, Dekaban GA, Medin JA.

Virol J. 2013 Jul 20;10:240. doi: 10.1186/1743-422X-10-240.


Systemic ceramide accumulation leads to severe and varied pathological consequences.

Alayoubi AM, Wang JC, Au BC, Carpentier S, Garcia V, Dworski S, El-Ghamrasni S, Kirouac KN, Exertier MJ, Xiong ZJ, Privé GG, Simonaro CM, Casas J, Fabrias G, Schuchman EH, Turner PV, Hakem R, Levade T, Medin JA.

EMBO Mol Med. 2013 Jun;5(6):827-42. doi: 10.1002/emmm.201202301. Epub 2013 May 16.


Tracking and evaluation of dendritic cell migration by cellular magnetic resonance imaging.

Dekaban GA, Hamilton AM, Fink CA, Au B, de Chickera SN, Ribot EJ, Foster PJ.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2013 Sep-Oct;5(5):469-83. doi: 10.1002/wnan.1227. Epub 2013 Apr 30. Review.


Rotational osteoplasty for femoral head fracture with cartilage loss.

Au B, Jamieson MD, Banerjee R.

Orthopedics. 2013 Jan;36(1):e105-8. doi: 10.3928/01477447-20121217-27.


A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response.

Chau JF, Jia D, Wang Z, Liu Z, Hu Y, Zhang X, Jia H, Lai KP, Leong WF, Au BJ, Mishina Y, Chen YG, Biondi C, Robertson E, Xie D, Liu H, He L, Wang X, Yu Q, Li B.

Nat Commun. 2012 May 15;3:836. doi: 10.1038/ncomms1832.


Prevalence of vertebral fracture in Asian men and women: comparison between Hong Kong, Thailand, Indonesia and Japan.

Kwok AW, Leung JC, Chan AY, Au BS, Lau EM, Yurianto H, Yuktanandana P, Yoshimura N, Muraki S, Oka H, Akune T, Leung PC.

Public Health. 2012 Jun;126(6):523-31. doi: 10.1016/j.puhe.2012.03.002. Epub 2012 May 5.


Atypical Atm-p53 genetic interaction in osteogenesis is mediated by Smad1 signaling.

Ma G, Li L, Hu Y, Chau JF, Au BJ, Jia D, Liu H, Yeh J, He L, Hao A, Li B.

J Mol Cell Biol. 2012 Apr;4(2):118-20. doi: 10.1093/jmcb/mjs006. No abstract available.


Lentivector transduction improves outcomes over transplantation of human HSCs alone in NOD/SCID/Fabry mice.

Pacienza N, Yoshimitsu M, Mizue N, Au BC, Wang JC, Fan X, Takenaka T, Medin JA.

Mol Ther. 2012 Jul;20(7):1454-61. doi: 10.1038/mt.2012.64. Epub 2012 Apr 3.


Engineered human Tmpk fused with truncated cell-surface markers: versatile cell-fate control safety cassettes.

Scaife M, Pacienza N, Au BC, Wang JC, Devine S, Scheid E, Lee CJ, Lopez-Perez O, Neschadim A, Fowler DH, Foley R, Medin JA.

Gene Ther. 2013 Jan;20(1):24-34. doi: 10.1038/gt.2011.210. Epub 2012 Jan 12.


Fluticasone, azithromycin and montelukast therapy in reducing corticosteroid exposure in bronchiolitis obliterans syndrome after allogeneic hematopoietic SCT: a case series of eight patients.

Norman BC, Jacobsohn DA, Williams KM, Au BK, Au MA, Lee SJ, Moravec CK, Chien JW.

Bone Marrow Transplant. 2011 Oct;46(10):1369-73. doi: 10.1038/bmt.2010.311. Epub 2010 Dec 6.


Bronchiolitis obliterans syndrome epidemiology after allogeneic hematopoietic cell transplantation.

Au BK, Au MA, Chien JW.

Biol Blood Marrow Transplant. 2011 Jul;17(7):1072-8. doi: 10.1016/j.bbmt.2010.11.018. Epub 2010 Nov 30.


Multicenter validation of a simplified score to predict massive transfusion in trauma.

Cotton BA, Dossett LA, Haut ER, Shafi S, Nunez TC, Au BK, Zaydfudim V, Johnston M, Arbogast P, Young PP.

J Trauma. 2010 Jul;69 Suppl 1:S33-9. doi: 10.1097/TA.0b013e3181e42411.


Room for (performance) improvement: provider-related factors associated with poor outcomes in massive transfusion.

Cotton BA, Dossett LA, Au BK, Nunez TC, Robertson AM, Young PP.

J Trauma. 2009 Nov;67(5):1004-12. doi: 10.1097/TA.0b013e3181bcb2a8.


Exsanguination protocol improves survival after major hepatic trauma.

Zaydfudim V, Dutton WD, Feurer ID, Au BK, Pinson CW, Cotton BA.

Injury. 2010 Jan;41(1):30-4. doi: 10.1016/j.injury.2009.09.019.


Hyperkalemia following massive transfusion in trauma.

Au BK, Dutton WD, Zaydfudim V, Nunez TC, Young PP, Cotton BA.

J Surg Res. 2009 Dec;157(2):284-9. doi: 10.1016/j.jss.2009.05.009. Epub 2009 Jun 6.


Vaccine-induced immunity circumvented by typical Mycobacterium tuberculosis Beijing strains.

Kremer K, van-der-Werf MJ, Au BK, Anh DD, Kam KM, van-Doorn HR, Borgdorff MW, van-Soolingen D.

Emerg Infect Dis. 2009 Feb;15(2):335-9.


Predefined massive transfusion protocols are associated with a reduction in organ failure and postinjury complications.

Cotton BA, Au BK, Nunez TC, Gunter OL, Robertson AM, Young PP.

J Trauma. 2009 Jan;66(1):41-8; discussion 48-9. doi: 10.1097/TA.0b013e31819313bb.


Optimizing outcomes in damage control resuscitation: identifying blood product ratios associated with improved survival.

Gunter OL Jr, Au BK, Isbell JM, Mowery NT, Young PP, Cotton BA.

J Trauma. 2008 Sep;65(3):527-34. doi: 10.1097/TA.0b013e3181826ddf.


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