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Items: 1 to 50 of 91


Extracellular phosphorylation drives the formation of neuronal circuitry.

Harada H, Farhani N, Wang XF, Sugita S, Charish J, Attisano L, Moran M, Cloutier JF, Reber M, Bremner R, Monnier PP.

Nat Chem Biol. 2019 Nov;15(11):1035-1042. doi: 10.1038/s41589-019-0345-z. Epub 2019 Aug 26.


A feed forward loop enforces YAP/TAZ signaling during tumorigenesis.

Gill MK, Christova T, Zhang YY, Gregorieff A, Zhang L, Narimatsu M, Song S, Xiong S, Couzens AL, Tong J, Krieger JR, Moran MF, Zlotta AR, van der Kwast TH, Gingras AC, Sicheri F, Wrana JL, Attisano L.

Nat Commun. 2018 Aug 29;9(1):3510. doi: 10.1038/s41467-018-05939-2.


Recent advances in understanding contextual TGFβ signaling.

Ayyaz A, Attisano L, Wrana JL.

F1000Res. 2017 May 26;6:749. doi: 10.12688/f1000research.11295.1. eCollection 2017. Review.


MARK4 inhibits Hippo signaling to promote proliferation and migration of breast cancer cells.

Heidary Arash E, Shiban A, Song S, Attisano L.

EMBO Rep. 2017 Mar;18(3):420-436. doi: 10.15252/embr.201642455. Epub 2017 Feb 9.


DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2.

Kwan J, Sczaniecka A, Heidary Arash E, Nguyen L, Chen CC, Ratkovic S, Klezovitch O, Attisano L, McNeill H, Emili A, Vasioukhin V.

Genes Dev. 2016 Dec 15;30(24):2696-2709. doi: 10.1101/gad.284539.116.


Analysis of Hippo and TGFβ signaling in polarizing epithelial cells and mouse embryos.

Narimatsu M, Labibi B, Wrana JL, Attisano L.

Differentiation. 2016 Apr-Jun;91(4-5):109-18. doi: 10.1016/j.diff.2016.01.003. Epub 2016 Jan 21.


SGK1 (glucose transport), dishevelled2 (wnt signaling), LC3/p62 (autophagy) and p53 (apoptosis) proteins are unaltered in Lafora disease.

Wang P, Israelian L, Xue Y, Song S, Attisano L, Minassian BA.

All Results J Biol. 2016;7(3):28-33.


Arhgef7 promotes activation of the Hippo pathway core kinase Lats.

Heidary Arash E, Song KM, Song S, Shiban A, Attisano L.

EMBO J. 2014 Dec 17;33(24):2997-3011. doi: 10.15252/embj.201490230. Epub 2014 Nov 25.


p21-Activated kinase (PAK) is required for Bone Morphogenetic Protein (BMP)-induced dendritogenesis in cortical neurons.

Podkowa M, Christova T, Zhao X, Jian Y, Attisano L.

Mol Cell Neurosci. 2013 Nov;57:83-92. doi: 10.1016/j.mcn.2013.10.005. Epub 2013 Oct 16.


The TGFbeta superfamily signaling pathway.

Weiss A, Attisano L.

Wiley Interdiscip Rev Dev Biol. 2013 Jan-Feb;2(1):47-63. doi: 10.1002/wdev.86. Epub 2012 Oct 5. Review.


Signal integration in TGF-β, WNT, and Hippo pathways.

Attisano L, Wrana JL.

F1000Prime Rep. 2013 Jun 3;5:17. doi: 10.12703/P5-17. Print 2013.


A role for Hipk in the Hippo pathway.

Heidary Arash E, Attisano L.

Sci Signal. 2013 May 14;6(275):pe18. doi: 10.1126/scisignal.2004259. Review.


The return of Dr Jekyll in cancer metastasis.

Attisano L, Wrana JL.

EMBO J. 2012 Dec 12;31(24):4486-7. doi: 10.1038/emboj.2012.316. Epub 2012 Nov 27. No abstract available.


Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells.

Bao R, Christova T, Song S, Angers S, Yan X, Attisano L.

PLoS One. 2012;7(11):e48670. doi: 10.1371/journal.pone.0048670. Epub 2012 Nov 7.


Wnt inhibitor screen reveals iron dependence of β-catenin signaling in cancers.

Song S, Christova T, Perusini S, Alizadeh S, Bao RY, Miller BW, Hurren R, Jitkova Y, Gronda M, Isaac M, Joseph B, Subramaniam R, Aman A, Chau A, Hogge DE, Weir SJ, Kasper J, Schimmer AD, Al-awar R, Wrana JL, Attisano L.

Cancer Res. 2011 Dec 15;71(24):7628-39. doi: 10.1158/0008-5472.CAN-11-2745. Epub 2011 Oct 18.


Naked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-catenin.

Van Raay TJ, Fortino NJ, Miller BW, Ma H, Lau G, Li C, Franklin JL, Attisano L, Solnica-Krezel L, Coffey RJ.

PLoS One. 2011 Apr 7;6(4):e18650. doi: 10.1371/journal.pone.0018650.


A skeleton in the closet: neogenin guides bone development.

Podkowa M, Attisano L.

Dev Cell. 2010 Jul 20;19(1):1-2. doi: 10.1016/j.devcel.2010.07.004.


The Hippo pathway regulates Wnt/beta-catenin signaling.

Varelas X, Miller BW, Sopko R, Song S, Gregorieff A, Fellouse FA, Sakuma R, Pawson T, Hunziker W, McNeill H, Wrana JL, Attisano L.

Dev Cell. 2010 Apr 20;18(4):579-91. doi: 10.1016/j.devcel.2010.03.007.


Microtubule stabilization by bone morphogenetic protein receptor-mediated scaffolding of c-Jun N-terminal kinase promotes dendrite formation.

Podkowa M, Zhao X, Chow CW, Coffey ET, Davis RJ, Attisano L.

Mol Cell Biol. 2010 May;30(9):2241-50. doi: 10.1128/MCB.01166-09. Epub 2010 Feb 22.


Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway.

Miller BW, Lau G, Grouios C, Mollica E, Barrios-Rodiles M, Liu Y, Datti A, Morris Q, Wrana JL, Attisano L.

Mol Syst Biol. 2009;5:315. doi: 10.1038/msb.2009.72. Epub 2009 Oct 13.


Regulation of planar cell polarity by Smurf ubiquitin ligases.

Narimatsu M, Bose R, Pye M, Zhang L, Miller B, Ching P, Sakuma R, Luga V, Roncari L, Attisano L, Wrana JL.

Cell. 2009 Apr 17;137(2):295-307. doi: 10.1016/j.cell.2009.02.025.


A concentration-dependent endocytic trap and sink mechanism converts Bmper from an activator to an inhibitor of Bmp signaling.

Kelley R, Ren R, Pi X, Wu Y, Moreno I, Willis M, Moser M, Ross M, Podkowa M, Attisano L, Patterson C.

J Cell Biol. 2009 Feb 23;184(4):597-609. doi: 10.1083/jcb.200808064. Epub 2009 Feb 16.


Sumoylation differentially regulates Goosecoid-mediated transcriptional repression.

Izzi L, Narimatsu M, Attisano L.

Exp Cell Res. 2008 Apr 15;314(7):1585-94. doi: 10.1016/j.yexcr.2008.01.023. Epub 2008 Feb 9.


Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development.

Silvestri C, Narimatsu M, von Both I, Liu Y, Tan NB, Izzi L, McCaffery P, Wrana JL, Attisano L.

Dev Cell. 2008 Mar;14(3):411-23. doi: 10.1016/j.devcel.2008.01.004. Erratum in: Dev Cell. 2008 Apr;14(4):633.


Foxh1 recruits Gsc to negatively regulate Mixl1 expression during early mouse development.

Izzi L, Silvestri C, von Both I, Labbé E, Zakin L, Wrana JL, Attisano L.

EMBO J. 2007 Jul 11;26(13):3132-43. Epub 2007 Jun 14.


Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis.

Labbé E, Lock L, Letamendia A, Gorska AE, Gryfe R, Gallinger S, Moses HL, Attisano L.

Cancer Res. 2007 Jan 1;67(1):75-84.


Endoglin increases eNOS expression by modulating Smad2 protein levels and Smad2-dependent TGF-beta signaling.

Santibanez JF, Letamendia A, Perez-Barriocanal F, Silvestri C, Saura M, Vary CP, Lopez-Novoa JM, Attisano L, Bernabeu C.

J Cell Physiol. 2007 Feb;210(2):456-68.


Embryonic cortical neural stem cells migrate ventrally and persist as postnatal striatal stem cells.

Willaime-Morawek S, Seaberg RM, Batista C, Labbé E, Attisano L, Gorski JA, Jones KR, Kam A, Morshead CM, van der Kooy D.

J Cell Biol. 2006 Oct 9;175(1):159-68.


Ubiquitin-dependent regulation of TGFbeta signaling in cancer.

Izzi L, Attisano L.

Neoplasia. 2006 Aug;8(8):677-88. Review.


DRAGON, a bone morphogenetic protein co-receptor.

Samad TA, Rebbapragada A, Bell E, Zhang Y, Sidis Y, Jeong SJ, Campagna JA, Perusini S, Fabrizio DA, Schneyer AL, Lin HY, Brivanlou AH, Attisano L, Woolf CJ.

J Biol Chem. 2005 Apr 8;280(14):14122-9. Epub 2005 Jan 25.


Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis.

Lee-Hoeflich ST, Causing CG, Podkowa M, Zhao X, Wrana JL, Attisano L.

EMBO J. 2004 Dec 8;23(24):4792-801. Epub 2004 Nov 11.


Foxh1 is essential for development of the anterior heart field.

von Both I, Silvestri C, Erdemir T, Lickert H, Walls JR, Henkelman RM, Rossant J, Harvey RP, Attisano L, Wrana JL.

Dev Cell. 2004 Sep;7(3):331-45.


Regulation of the TGFbeta signalling pathway by ubiquitin-mediated degradation.

Izzi L, Attisano L.

Oncogene. 2004 Mar 15;23(11):2071-8. Review.


TGFbeta and Wnt pathway cross-talk.

Attisano L, Labbé E.

Cancer Metastasis Rev. 2004 Jan-Jun;23(1-2):53-61. Review.


The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase.

Subramaniam V, Li H, Wong M, Kitching R, Attisano L, Wrana J, Zubovits J, Burger AM, Seth A.

Br J Cancer. 2003 Oct 20;89(8):1538-44.


Myostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesis.

Rebbapragada A, Benchabane H, Wrana JL, Celeste AJ, Attisano L.

Mol Cell Biol. 2003 Oct;23(20):7230-42.


TGF-beta1-mediated alterations of renal proximal tubular epithelial cell phenotype.

Tian YC, Fraser D, Attisano L, Phillips AO.

Am J Physiol Renal Physiol. 2003 Jul;285(1):F130-42. Epub 2003 Mar 18.


Signal transduction by the TGF-beta superfamily.

Attisano L, Wrana JL.

Science. 2002 May 31;296(5573):1646-7. Review.


The Smads.

Attisano L, Lee-Hoeflich ST.

Genome Biol. 2001;2(8):REVIEWS3010. Epub 2001 Aug 2. Review.


Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression.

Sánchez-Elsner T, Botella LM, Velasco B, Corbí A, Attisano L, Bernabéu C.

J Biol Chem. 2001 Oct 19;276(42):38527-35. Epub 2001 Aug 2.


The transcriptional role of Smads and FAST (FoxH1) in TGFbeta and activin signalling.

Attisano L, Silvestri C, Izzi L, Labbé E.

Mol Cell Endocrinol. 2001 Jun 30;180(1-2):3-11. Review.


Cross-talk between the p42/p44 MAP kinase and Smad pathways in transforming growth factor beta 1-induced furin gene transactivation.

Blanchette F, Rivard N, Rudd P, Grondin F, Attisano L, Dubois CM.

J Biol Chem. 2001 Sep 7;276(36):33986-94. Epub 2001 Jul 11.


Involvement of Smads in TGFbeta1-induced furin (fur) transcription.

Blanchette F, Rudd P, Grondin F, Attisano L, Dubois CM.

J Cell Physiol. 2001 Aug;188(2):264-73.


FoxH1 (Fast) functions to specify the anterior primitive streak in the mouse.

Hoodless PA, Pye M, Chazaud C, Labbé E, Attisano L, Rossant J, Wrana JL.

Genes Dev. 2001 May 15;15(10):1257-71.


Transcriptional regulation by Smads: crosstalk between the TGF-beta and Wnt pathways.

Letamendia A, Labbé E, Attisano L.

J Bone Joint Surg Am. 2001;83-A Suppl 1(Pt 1):S31-9. Review.


Characterization of Smad phosphorylation and Smad-receptor interaction.

Mehra A, Attisano L, Wrana JL.

Methods Mol Biol. 2000;142:67-78. Review. No abstract available.


Smads as transcriptional co-modulators.

Attisano L, Wrana JL.

Curr Opin Cell Biol. 2000 Apr;12(2):235-43. Review.


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