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The membrane type matrix metalloproteinase MMP14 mediates constitutive shedding of MHC class I chain-related molecule A independent of A disintegrin and metalloproteinases.

Liu G, Atteridge CL, Wang X, Lundgren AD, Wu JD.

J Immunol. 2010 Apr 1;184(7):3346-50. doi: 10.4049/jimmunol.0903789. Epub 2010 Mar 5.


Obstructing shedding of the immunostimulatory MHC class I chain-related gene B prevents tumor formation.

Wu JD, Atteridge CL, Wang X, Seya T, Plymate SR.

Clin Cancer Res. 2009 Jan 15;15(2):632-40. doi: 10.1158/1078-0432.CCR-08-1305.

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