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Items: 1 to 50 of 59

1.

cGMP-dependent protein kinase I in vascular smooth muscle cells improves ischemic stroke outcome in mice.

Shvedova M, Litvak MM, Roberts JD Jr, Fukumura D, Suzuki T, Şencan İ, Li G, Reventun P, Buys ES, Kim HH, Sakadžić S, Ayata C, Huang PL, Feil R, Atochin DN.

J Cereb Blood Flow Metab. 2019 Aug 18:271678X19870583. doi: 10.1177/0271678X19870583. [Epub ahead of print]

PMID:
31423931
2.

Somatostatin+/nNOS+ neurons are involved in delta electroencephalogram activity and cortical-dependent recognition memory.

Zielinski MR, Atochin DN, McNally JM, McKenna JT, Huang PL, Strecker RE, Gerashchenko D.

Sleep. 2019 Oct 9;42(10). pii: zsz143. doi: 10.1093/sleep/zsz143.

PMID:
31328777
3.

Protective Effects of a New C-Jun N-terminal Kinase Inhibitor in the Model of Global Cerebral Ischemia in Rats.

Plotnikov MB, Chernysheva GA, Aliev OI, Smol'iakova VI, Fomina TI, Osipenko AN, Rydchenko VS, Anfinogenova YJ, Khlebnikov AI, Schepetkin IA, Atochin DN.

Molecules. 2019 May 3;24(9). pii: E1722. doi: 10.3390/molecules24091722.

4.

Synthesis, biological evaluation, and molecular modeling of 11H-indeno[1,2-b]quinoxalin-11-one derivatives and tryptanthrin-6-oxime as c-Jun N-terminal kinase inhibitors.

Schepetkin IA, Khlebnikov AI, Potapov AS, Kovrizhina AR, Matveevskaya VV, Belyanin ML, Atochin DN, Zanoza SO, Gaidarzhy NM, Lyakhov SA, Kirpotina LN, Quinn MT.

Eur J Med Chem. 2019 Jan 1;161:179-191. doi: 10.1016/j.ejmech.2018.10.023. Epub 2018 Oct 12.

PMID:
30347329
5.

Oral nitrite restores age-dependent phenotypes in eNOS-null mice.

Tenopoulou M, Doulias PT, Nakamoto K, Berrios K, Zura G, Li C, Faust M, Yakovishina V, Evans P, Tan L, Bennett MJ, Snyder NW, Quinn WJ 3rd, Baur JA, Atochin DN, Huang PL, Ischiropoulos H.

JCI Insight. 2018 Aug 23;3(16). pii: 122156. doi: 10.1172/jci.insight.122156. eCollection 2018 Aug 23.

6.

c-Jun N-Terminal Kinases (JNKs) in Myocardial and Cerebral Ischemia/Reperfusion Injury.

Shvedova M, Anfinogenova Y, Atochina-Vasserman EN, Schepetkin IA, Atochin DN.

Front Pharmacol. 2018 Jul 5;9:715. doi: 10.3389/fphar.2018.00715. eCollection 2018. Review.

7.

Haplotype analysis of endothelial nitric oxide synthase (NOS3) genetic variants and metabolic syndrome in healthy subjects and schizophrenia patients.

Fattakhov N, Smirnova L, Atochin D, Parshukova D, Skuratovskaia D, Painter Q, Zatolokin P, Semke A, Litvinova L, Ivanova S.

Int J Obes (Lond). 2018 Dec;42(12):2036-2046. doi: 10.1038/s41366-018-0124-z. Epub 2018 Jun 15.

8.

Connexins and Nitric Oxide Inside and Outside Mitochondria: Significance for Cardiac Protection and Adaptation.

Shvedova M, Anfinogenova Y, Popov SV, Atochin DN.

Front Physiol. 2018 May 16;9:479. doi: 10.3389/fphys.2018.00479. eCollection 2018. Review.

9.

Quantitative assessment of demyelination in ischemic stroke in vivo using macromolecular proton fraction mapping.

Khodanovich MY, Kisel AA, Akulov AE, Atochin DN, Kudabaeva MS, Glazacheva VY, Svetlik MV, Medvednikova YA, Mustafina LR, Yarnykh VL.

J Cereb Blood Flow Metab. 2018 May;38(5):919-931. doi: 10.1177/0271678X18755203. Epub 2018 Jan 26. Erratum in: J Cereb Blood Flow Metab. 2018 Jan 1;:271678X18761472.

10.

Cell-Based Drug Delivery and Use of Nano-and Microcarriers for Cell Functionalization.

Timin AS, Litvak MM, Gorin DA, Atochina-Vasserman EN, Atochin DN, Sukhorukov GB.

Adv Healthc Mater. 2018 Feb;7(3). doi: 10.1002/adhm.201700818. Epub 2017 Nov 30. Review.

PMID:
29193876
11.

An improved three-vessel occlusion model of global cerebral ischemia in rats.

Atochin DN, Chernysheva GA, Aliev OI, Smolyakova VI, Osipenko AN, Logvinov SV, Zhdankina AA, Plotnikova TM, Plotnikov MB.

Brain Res Bull. 2017 Jun;132:213-221. doi: 10.1016/j.brainresbull.2017.06.005. Epub 2017 Jun 8.

PMID:
28603012
12.

[JUN N-TERMINAL KINASES AND THEIR PHARMACOLOGICAL MODULATION OF ISCHE-MIC AND REPERFUSION INJURY OF THE BRAIN].

Shvedova MV, Anfinogenova YD, Schepetkin IA, Atochin DN.

Ross Fiziol Zh Im I M Sechenova. 2017 Mar;103(3):268-83. Review. Russian.

PMID:
30199207
13.

Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury.

Carnemolla R, Villa CH, Greineder CF, Zaitsev S, Patel KR, Kowalska MA, Atochin DN, Cines DB, Siegel DL, Esmon CT, Muzykantov VR.

FASEB J. 2017 Feb;31(2):761-770. doi: 10.1096/fj.201600912R. Epub 2016 Nov 11.

14.

Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice.

Tanigaki K, Chambliss KL, Yuhanna IS, Sacharidou A, Ahmed M, Atochin DN, Huang PL, Shaul PW, Mineo C.

Diabetes. 2016 Jul;65(7):1996-2005. doi: 10.2337/db15-1605. Epub 2016 Apr 26.

15.

Neuroprotective effects of p-tyrosol after the global cerebral ischemia in rats.

Atochin DN, Chernysheva GA, Smolyakova VI, Osipenko AN, Logvinov SV, Zhdankina AA, Sysolyatin SV, Kryukov YA, Anfinogenova Y, Plotnikova TM, Plotnikov MB.

Phytomedicine. 2016 Jun 15;23(7):784-92. doi: 10.1016/j.phymed.2016.03.015. Epub 2016 Apr 22.

PMID:
27180226
16.

A novel dual NO-donating oxime and c-Jun N-terminal kinase inhibitor protects against cerebral ischemia-reperfusion injury in mice.

Atochin DN, Schepetkin IA, Khlebnikov AI, Seledtsov VI, Swanson H, Quinn MT, Huang PL.

Neurosci Lett. 2016 Apr 8;618:45-49. doi: 10.1016/j.neulet.2016.02.033. Epub 2016 Feb 26.

17.

Nitric oxide and mitochondria in metabolic syndrome.

Litvinova L, Atochin DN, Fattakhov N, Vasilenko M, Zatolokin P, Kirienkova E.

Front Physiol. 2015 Feb 17;6:20. doi: 10.3389/fphys.2015.00020. eCollection 2015. Review.

18.

Role of adiponectin and proinflammatory gene expression in adipose tissue chronic inflammation in women with metabolic syndrome.

Litvinova L, Atochin D, Vasilenko M, Fattakhov N, Zatolokin P, Vaysbeyn I, Kirienkova E.

Diabetol Metab Syndr. 2014 Dec 9;6(1):137. doi: 10.1186/1758-5996-6-137. eCollection 2014.

19.

Endothelial dysfunction abrogates the efficacy of normobaric hyperoxia in stroke.

Shin HK, Oka F, Kim JH, Atochin D, Huang PL, Ayata C.

J Neurosci. 2014 Nov 12;34(46):15200-7. doi: 10.1523/JNEUROSCI.1110-14.2014.

20.

Through-skull fluorescence imaging of the brain in a new near-infrared window.

Hong G, Diao S, Chang J, Antaris AL, Chen C, Zhang B, Zhao S, Atochin DN, Huang PL, Andreasson KI, Kuo CJ, Dai H.

Nat Photonics. 2014 Sep;8(9):723-730. Epub 2014 Aug 3.

21.

Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice.

Pong T, Scherrer-Crosbie M, Atochin DN, Bloch KD, Huang PL.

PLoS One. 2014 Jan 21;9(1):e85946. doi: 10.1371/journal.pone.0085946. eCollection 2014.

22.

Anti-inflammatory effect of targeted delivery of SOD to endothelium: mechanism, synergism with NO donors and protective effects in vitro and in vivo.

Shuvaev VV, Han J, Tliba S, Arguiri E, Christofidou-Solomidou M, Ramirez SH, Dykstra H, Persidsky Y, Atochin DN, Huang PL, Muzykantov VR.

PLoS One. 2013 Oct 11;8(10):e77002. doi: 10.1371/journal.pone.0077002. eCollection 2013.

23.

Deficient eNOS phosphorylation is a mechanism for diabetic vascular dysfunction contributing to increased stroke size.

Li Q, Atochin D, Kashiwagi S, Earle J, Wang A, Mandeville E, Hayakawa K, d'Uscio LV, Lo EH, Katusic Z, Sessa W, Huang PL.

Stroke. 2013 Nov;44(11):3183-8. doi: 10.1161/STROKEAHA.113.002073. Epub 2013 Aug 29.

24.

Hyperlipidemia disrupts cerebrovascular reflexes and worsens ischemic perfusion defect.

Ayata C, Shin HK, Dileköz E, Atochin DN, Kashiwagi S, Eikermann-Haerter K, Huang PL.

J Cereb Blood Flow Metab. 2013 Jun;33(6):954-62. doi: 10.1038/jcbfm.2013.38. Epub 2013 Mar 13.

25.

Cerebral blood volume affects blood-brain barrier integrity in an acute transient stroke model.

Huang S, Kim JK, Atochin DN, Farrar CT, Huang PL, Suh JY, Kwon SJ, Shim WH, Cho H, Cho G, Kim YR.

J Cereb Blood Flow Metab. 2013 Jun;33(6):898-905. doi: 10.1038/jcbfm.2013.27. Epub 2013 Mar 6.

26.

eNOS phosphorylation on serine 1176 affects insulin sensitivity and adiposity.

Kashiwagi S, Atochin DN, Li Q, Schleicher M, Pong T, Sessa WC, Huang PL.

Biochem Biophys Res Commun. 2013 Feb 8;431(2):284-90. doi: 10.1016/j.bbrc.2012.12.110. Epub 2013 Jan 3.

27.

C-reactive protein causes insulin resistance in mice through Fcγ receptor IIB-mediated inhibition of skeletal muscle glucose delivery.

Tanigaki K, Vongpatanasin W, Barrera JA, Atochin DN, Huang PL, Bonvini E, Shaul PW, Mineo C.

Diabetes. 2013 Mar;62(3):721-31. doi: 10.2337/db12-0133. Epub 2012 Oct 15.

28.

A novel hydrogen sulfide-releasing N-methyl-D-aspartate receptor antagonist prevents ischemic neuronal death.

Marutani E, Kosugi S, Tokuda K, Khatri A, Nguyen R, Atochin DN, Kida K, Van Leyen K, Arai K, Ichinose F.

J Biol Chem. 2012 Sep 14;287(38):32124-35. doi: 10.1074/jbc.M112.374124. Epub 2012 Jul 19.

29.

Nitric oxide synthase 3 deficiency limits adverse ventricular remodeling after pressure overload in insulin resistance.

Kurtz B, Thibault HB, Raher MJ, Popovich JR, Cawley S, Atochin DN, Hayton S, Shakartzi HR, Huang PL, Bloch KD, Buys E, Scherrer-Crosbie M.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H2093-101. doi: 10.1152/ajpheart.00744.2010. Epub 2011 Aug 19.

30.

[Interaction of neuronal NOS and catecholamines in regulation of expression of proteins of apoptosis by vasopressinergic hypothalamic neurons].

Chernigovskaia EV, Iamova LA, Atochin D, Huang P, Glazova MV.

Zh Evol Biokhim Fiziol. 2011 May-Jun;47(3):232-8. Russian.

PMID:
21780643
31.

Delayed paraplegia after spinal cord ischemic injury requires caspase-3 activation in mice.

Kakinohana M, Kida K, Minamishima S, Atochin DN, Huang PL, Kaneki M, Ichinose F.

Stroke. 2011 Aug;42(8):2302-7. doi: 10.1161/STROKEAHA.110.600429. Epub 2011 Jun 23.

32.

Optical coherence tomography for the quantitative study of cerebrovascular physiology.

Srinivasan VJ, Atochin DN, Radhakrishnan H, Jiang JY, Ruvinskaya S, Wu W, Barry S, Cable AE, Ayata C, Huang PL, Boas DA.

J Cereb Blood Flow Metab. 2011 Jun;31(6):1339-45. doi: 10.1038/jcbfm.2011.19. Epub 2011 Mar 2.

33.

Role of endothelial nitric oxide in cerebrovascular regulation.

Atochin DN, Huang PL.

Curr Pharm Biotechnol. 2011 Sep;12(9):1334-42. Review.

34.

Endothelial nitric oxide synthase transgenic models of endothelial dysfunction.

Atochin DN, Huang PL.

Pflugers Arch. 2010 Nov;460(6):965-74. doi: 10.1007/s00424-010-0867-4. Epub 2010 Aug 10. Review.

35.

Immunohistochemical expression of Bcl-2, p53 and caspase-9 in hypothalamus magnocellular centers of nNOS knockout mice following water deprivation.

Chernigovskaya E, Atochin D, Yamova L, Huang P, Glazova M.

Biotech Histochem. 2011 Oct;86(5):333-9. doi: 10.3109/10520295.2010.501706. Epub 2010 Jul 22.

PMID:
20662604
36.

Soluble guanylate cyclase alpha1beta1 limits stroke size and attenuates neurological injury.

Atochin DN, Yuzawa I, Li Q, Rauwerdink KM, Malhotra R, Chang J, Brouckaert P, Ayata C, Moskowitz MA, Bloch KD, Huang PL, Buys ES.

Stroke. 2010 Aug;41(8):1815-9. doi: 10.1161/STROKEAHA.109.577635. Epub 2010 Jul 1.

37.

The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.

Schleicher M, Yu J, Murata T, Derakhshan B, Atochin D, Qian L, Kashiwagi S, Di Lorenzo A, Harrison KD, Huang PL, Sessa WC.

Sci Signal. 2009 Aug 4;2(82):ra41. doi: 10.1126/scisignal.2000343.

38.

In vivo quantification of transvascular water exchange during the acute phase of permanent stroke.

Kim YR, Tejima E, Huang S, Atochin DN, Dai G, Lo EH, Huang PL, Bogdanov A Jr, Rosen BR.

Magn Reson Med. 2008 Oct;60(4):813-21. doi: 10.1002/mrm.21708.

39.

Cerebrovascular thromboprophylaxis in mice by erythrocyte-coupled tissue-type plasminogen activator.

Danielyan K, Ganguly K, Ding BS, Atochin D, Zaitsev S, Murciano JC, Huang PL, Kasner SE, Cines DB, Muzykantov VR.

Circulation. 2008 Sep 30;118(14):1442-9. doi: 10.1161/CIRCULATIONAHA.107.750257. Epub 2008 Sep 15.

40.

Effects of neuroglobin overexpression on acute brain injury and long-term outcomes after focal cerebral ischemia.

Wang X, Liu J, Zhu H, Tejima E, Tsuji K, Murata Y, Atochin DN, Huang PL, Zhang C, Lo EH.

Stroke. 2008 Jun;39(6):1869-74. doi: 10.1161/STROKEAHA.107.506022. Epub 2008 Apr 10.

41.

Contributions of nitric oxide synthase isoforms to pulmonary oxygen toxicity, local vs. mediated effects.

Demchenko IT, Atochin DN, Gutsaeva DR, Godfrey RR, Huang PL, Piantadosi CA, Allen BW.

Am J Physiol Lung Cell Mol Physiol. 2008 May;294(5):L984-90. doi: 10.1152/ajplung.00420.2007. Epub 2008 Mar 7.

42.

Reduction of hippocampal cell death and proteolytic responses in tissue plasminogen activator knockout mice after transient global cerebral ischemia.

Lee SR, Lok J, Rosell A, Kim HY, Murata Y, Atochin D, Huang PL, Wang X, Ayata C, Moskowitz MA, Lo EH.

Neuroscience. 2007 Nov 30;150(1):50-7. Epub 2007 Oct 23.

43.

Role of neuronal nitric oxide in the regulation of vasopressin expression and release in response to inhibition of catecholamine synthesis and dehydration.

Yamova L, Atochin D, Glazova M, Chernigovskaya E, Huang P.

Neurosci Lett. 2007 Oct 22;426(3):160-5. Epub 2007 Sep 11.

44.

The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo.

Atochin DN, Wang A, Liu VW, Critchlow JD, Dantas AP, Looft-Wilson R, Murata T, Salomone S, Shin HK, Ayata C, Moskowitz MA, Michel T, Sessa WC, Huang PL.

J Clin Invest. 2007 Jul;117(7):1961-7.

45.

Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia.

Tsuji K, Aoki T, Tejima E, Arai K, Lee SR, Atochin DN, Huang PL, Wang X, Montaner J, Lo EH.

Stroke. 2005 Sep;36(9):1954-9. Epub 2005 Jul 28.

PMID:
16051896
46.

Mouse model of microembolic stroke and reperfusion.

Atochin DN, Murciano JC, Gürsoy-Ozdemir Y, Krasik T, Noda F, Ayata C, Dunn AK, Moskowitz MA, Huang PL, Muzykantov VR.

Stroke. 2004 Sep;35(9):2177-82. Epub 2004 Jul 15.

PMID:
15256680
48.

Contributions of endothelial and neuronal nitric oxide synthases to cerebrovascular responses to hyperoxia.

Atochin DN, Demchenko IT, Astern J, Boso AE, Piantadosi CA, Huang PL.

J Cereb Blood Flow Metab. 2003 Oct;23(10):1219-26.

PMID:
14526232
49.

Oxygen seizure latency and peroxynitrite formation in mice lacking neuronal or endothelial nitric oxide synthases.

Demchenko IT, Atochin DN, Boso AE, Astern J, Huang PL, Piantadosi CA.

Neurosci Lett. 2003 Jun 19;344(1):53-6.

PMID:
12781920
50.

Rapid cerebral ischemic preconditioning in mice deficient in endothelial and neuronal nitric oxide synthases.

Atochin DN, Clark J, Demchenko IT, Moskowitz MA, Huang PL.

Stroke. 2003 May;34(5):1299-303. Epub 2003 Apr 3.

PMID:
12677017

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