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Items: 1 to 50 of 368

1.

Regulated hAAT Expression from a Novel rAAV Vector and Its Application in the Prevention of Type 1 Diabetes.

Ma H, Lu Y, Lowe K, van der Meijden-Erkelens L, Wasserfall C, Atkinson MA, Song S.

J Clin Med. 2019 Aug 28;8(9). pii: E1321. doi: 10.3390/jcm8091321.

2.

Genetic risk for autoimmunity is associated with distinct changes in the human gut microbiome.

Russell JT, Roesch LFW, Ördberg M, Ilonen J, Atkinson MA, Schatz DA, Triplett EW, Ludvigsson J.

Nat Commun. 2019 Aug 9;10(1):3621. doi: 10.1038/s41467-019-11460-x.

3.

The Influence of Type 2 Diabetes-Associated Factors on Type 1 Diabetes.

Redondo MJ, Evans-Molina C, Steck AK, Atkinson MA, Sosenko J.

Diabetes Care. 2019 Aug;42(8):1357-1364. doi: 10.2337/dc19-0102. Epub 2019 Jun 4.

PMID:
31167894
4.

Pleiotropic roles of the insulin-like growth factor axis in type 1 diabetes.

Shapiro MR, Atkinson MA, Brusko TM.

Curr Opin Endocrinol Diabetes Obes. 2019 Aug;26(4):188-194. doi: 10.1097/MED.0000000000000484.

PMID:
31145130
5.

NIH Initiative to Improve Understanding of the Pancreas, Islet, and Autoimmunity in Type 1 Diabetes: The Human Pancreas Analysis Program (HPAP).

Kaestner KH, Powers AC, Naji A; HPAP Consortium, Atkinson MA.

Diabetes. 2019 Jul;68(7):1394-1402. doi: 10.2337/db19-0058. Epub 2019 May 24. Review.

PMID:
31127054
6.

Dual-Sized Microparticle System for Generating Suppressive Dendritic Cells Prevents and Reverses Type 1 Diabetes in the Nonobese Diabetic Mouse Model.

Lewis JS, Stewart JM, Marshall GP, Carstens MR, Zhang Y, Dolgova NV, Xia C, Brusko TM, Wasserfall CH, Clare-Salzler MJ, Atkinson MA, Keselowsky BG.

ACS Biomater Sci Eng. 2019 May 13;5(5):2631-2646. doi: 10.1021/acsbiomaterials.9b00332. Epub 2019 Mar 26.

7.

Islet amyloidosis in a child with type 1 diabetes.

Beery ML, Jacobsen LM, Atkinson MA, Butler AE, Campbell-Thompson M.

Islets. 2019;11(2):44-49. doi: 10.1080/19382014.2019.1599707. Epub 2019 May 14.

8.

Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence. Reply to Skog O, Klingel K, Roivainen M et al [letter].

Dunne JL, Richardson SJ, Atkinson MA, Craig ME, Dahl-Jørgensen K, Flodström-Tullberg M, Hyöty H, Lloyd RE, Morgan NG, Pugliese A.

Diabetologia. 2019 Jun;62(6):1100-1103. doi: 10.1007/s00125-019-4873-6. Epub 2019 Apr 23. No abstract available.

PMID:
31016358
9.

Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA1c, and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data.

Haller MJ, Long SA, Blanchfield JL, Schatz DA, Skyler JS, Krischer JP, Bundy BN, Geyer SM, Warnock MV, Miller JL, Atkinson MA, Becker DJ, Baidal DA, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Herold KC, Marks JB, Moran A, Rodriguez H, Russell WE, Wilson DM, Greenbaum CJ; Type 1 Diabetes TrialNet ATG-GCSF Study Group.

Diabetes. 2019 Jun;68(6):1267-1276. doi: 10.2337/db19-0057. Epub 2019 Apr 9.

PMID:
30967424
10.

Hepcidin and arterial stiffness in children with systemic lupus erythematosus and lupus nephritis: A cross-sectional study.

Atkinson MA, Joo S, Sule S.

PLoS One. 2019 Mar 29;14(3):e0214248. doi: 10.1371/journal.pone.0214248. eCollection 2019.

11.

Amnioinfusions to Treat Early Onset Anhydramnios Caused by Renal Anomalies: Background and Rationale for the Renal Anhydramnios Fetal Therapy Trial.

O'Hare EM, Jelin AC, Miller JL, Ruano R, Atkinson MA, Baschat AA, Jelin EB.

Fetal Diagn Ther. 2019;45(6):365-372. doi: 10.1159/000497472. Epub 2019 Mar 21. Review.

12.

Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the Avy obesity-associated gene.

Yong J, Tian J, Dang H, Wu TT, Atkinson MA, Sun R, Kaufman DL.

Sci Rep. 2019 Mar 12;9(1):4269. doi: 10.1038/s41598-019-38905-z.

13.

Boosting to Amplify Signal with Isobaric Labeling (BASIL) Strategy for Comprehensive Quantitative Phosphoproteomic Characterization of Small Populations of Cells.

Yi L, Tsai CF, Dirice E, Swensen AC, Chen J, Shi T, Gritsenko MA, Chu RK, Piehowski PD, Smith RD, Rodland KD, Atkinson MA, Mathews CE, Kulkarni RN, Liu T, Qian WJ.

Anal Chem. 2019 May 7;91(9):5794-5801. doi: 10.1021/acs.analchem.9b00024. Epub 2019 Mar 15.

14.

Untargeted metabolomic analysis in non-fasted diabetic dogs by UHPLC-HRMS.

O'Kell AL, Garrett TJ, Wasserfall C, Atkinson MA.

Metabolomics. 2019 Jan 22;15(2):15. doi: 10.1007/s11306-019-1477-6.

PMID:
30830416
15.

Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes.

Wang YJ, Traum D, Schug J, Gao L, Liu C; HPAP Consortium, Atkinson MA, Powers AC, Feldman MD, Naji A, Chang KM, Kaestner KH.

Cell Metab. 2019 Mar 5;29(3):769-783.e4. doi: 10.1016/j.cmet.2019.01.003. Epub 2019 Jan 31.

PMID:
30713110
16.

A Map of Human Type 1 Diabetes Progression by Imaging Mass Cytometry.

Damond N, Engler S, Zanotelli VRT, Schapiro D, Wasserfall CH, Kusmartseva I, Nick HS, Thorel F, Herrera PL, Atkinson MA, Bodenmiller B.

Cell Metab. 2019 Mar 5;29(3):755-768.e5. doi: 10.1016/j.cmet.2018.11.014. Epub 2019 Jan 31.

PMID:
30713109
17.

Clinical features, biochemistry and HLA-DRB1 status in youth-onset type 1 diabetes in Pakistan.

Fawwad A, Govender D, Ahmedani MY, Basit A, Lane JA, Mack SJ, Atkinson MA, Henry Wasserfall C, Ogle GD, Noble JA.

Diabetes Res Clin Pract. 2019 Mar;149:9-17. doi: 10.1016/j.diabres.2019.01.023. Epub 2019 Jan 30.

PMID:
30710658
18.

Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas.

Moin ASM, Montemurro C, Zeng K, Cory M, Nguyen M, Kulkarni S, Fritsch H, Meier JJ, Dhawan S, Rizza RA, Atkinson MA, Butler AE.

Front Endocrinol (Lausanne). 2019 Jan 9;9:791. doi: 10.3389/fendo.2018.00791. eCollection 2018.

19.

Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes.

Dunne JL, Richardson SJ, Atkinson MA, Craig ME, Dahl-Jørgensen K, Flodström-Tullberg M, Hyöty H, Insel RA, Lernmark Å, Lloyd RE, Morgan NG, Pugliese A.

Diabetologia. 2019 May;62(5):744-753. doi: 10.1007/s00125-019-4811-7. Epub 2019 Jan 23.

20.

Type 1 Diabetes Risk in African-Ancestry Participants and Utility of an Ancestry-Specific Genetic Risk Score.

Onengut-Gumuscu S, Chen WM, Robertson CC, Bonnie JK, Farber E, Zhu Z, Oksenberg JR, Brant SR, Bridges SL Jr, Edberg JC, Kimberly RP, Gregersen PK, Rewers MJ, Steck AK, Black MH, Dabelea D, Pihoker C, Atkinson MA, Wagenknecht LE, Divers J, Bell RA; SEARCH for Diabetes in Youth; Type 1 Diabetes Genetics Consortium, Erlich HA, Concannon P, Rich SS.

Diabetes Care. 2019 Mar;42(3):406-415. doi: 10.2337/dc18-1727. Epub 2019 Jan 18.

PMID:
30659077
21.

Relative Pancreas Volume Is Reduced in First-Degree Relatives of Patients With Type 1 Diabetes.

Campbell-Thompson ML, Filipp SL, Grajo JR, Nambam B, Beegle R, Middlebrooks EH, Gurka MJ, Atkinson MA, Schatz DA, Haller MJ.

Diabetes Care. 2019 Feb;42(2):281-287. doi: 10.2337/dc18-1512. Epub 2018 Dec 14.

PMID:
30552130
22.

The challenge of modulating β-cell autoimmunity in type 1 diabetes.

Atkinson MA, Roep BO, Posgai A, Wheeler DCS, Peakman M.

Lancet Diabetes Endocrinol. 2019 Jan;7(1):52-64. doi: 10.1016/S2213-8587(18)30112-8. Epub 2018 Oct 24. Review.

PMID:
30528099
23.

Transcription Factor 7-Like 2 (TCF7L2) Gene Polymorphism and Progression From Single to Multiple Autoantibody Positivity in Individuals at Risk for Type 1 Diabetes.

Redondo MJ, Steck AK, Sosenko J, Anderson M, Antinozzi P, Michels A, Wentworth JM, Atkinson MA, Pugliese A, Geyer S; Type 1 Diabetes TrialNet Study Group.

Diabetes Care. 2018 Dec;41(12):2480-2486. doi: 10.2337/dc18-0861. Epub 2018 Oct 1.

PMID:
30275285
24.

Epidemiology of childhood-onset type 1 diabetes in Azerbaijan: Incidence, clinical features, biochemistry, and HLA-DRB1 status.

Ahmadov GA, Govender D, Atkinson MA, Sultanova RA, Eubova AA, Wasserfall CH, Mack SJ, Lane JA, Noble JA, Ogle GD.

Diabetes Res Clin Pract. 2018 Oct;144:252-259. doi: 10.1016/j.diabres.2018.09.009. Epub 2018 Sep 13.

PMID:
30218742
25.

Nanowell-mediated two-dimensional liquid chromatography enables deep proteome profiling of <1000 mammalian cells.

Dou M, Zhu Y, Liyu A, Liang Y, Chen J, Piehowski PD, Xu K, Zhao R, Moore RJ, Atkinson MA, Mathews CE, Qian WJ, Kelly RT.

Chem Sci. 2018 Jul 18;9(34):6944-6951. doi: 10.1039/c8sc02680g. eCollection 2018 Sep 14.

26.

Genetic associations of hemoglobin in children with chronic kidney disease in the PediGFR Consortium.

Atkinson MA, Xiao R, Köttgen A, Wühl E, Wong CS, Wuttke M, Bayazit AK, Çalişkan S, Warady BA, Schaefer F, Furth SL.

Pediatr Res. 2019 Feb;85(3):324-328. doi: 10.1038/s41390-018-0148-z. Epub 2018 Aug 15.

27.

Islet-Derived eATP Fuels Autoreactive CD8+ T Cells and Facilitates the Onset of Type 1 Diabetes.

Tezza S, Ben Nasr M, D'Addio F, Vergani A, Usuelli V, Falzoni S, Bassi R, Dellepiane S, Fotino C, Rossi C, Maestroni A, Solini A, Corradi D, Giani E, Mameli C, Bertuzzi F, Pezzolesi MG, Wasserfall CH, Atkinson MA, Füchtbauer EM, Ricordi C, Folli F, Di Virgilio F, Pileggi A, Dhe-Paganon S, Zuccotti GV, Fiorina P.

Diabetes. 2018 Oct;67(10):2038-2053. doi: 10.2337/db17-1227. Epub 2018 Jul 31.

28.

How social is social inhibition of return?

Atkinson MA, Millett AC, Doneva SP, Simpson A, Cole GG.

Atten Percept Psychophys. 2018 Nov;80(8):1892-1903. doi: 10.3758/s13414-018-1546-3.

PMID:
30014316
29.

Low-Dose Anti-Thymocyte Globulin (ATG) Preserves β-Cell Function and Improves HbA1c in New-Onset Type 1 Diabetes.

Haller MJ, Schatz DA, Skyler JS, Krischer JP, Bundy BN, Miller JL, Atkinson MA, Becker DJ, Baidal D, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Herold KC, Marks JB, Moran A, Rodriguez H, Russell W, Wilson DM, Greenbaum CJ; Type 1 Diabetes TrialNet ATG-GCSF Study Group.

Diabetes Care. 2018 Sep;41(9):1917-1925. doi: 10.2337/dc18-0494. Epub 2018 Jul 16.

30.

Vitamin D insufficiency, hemoglobin, and anemia in children with chronic kidney disease.

Altemose KE, Kumar J, Portale AA, Warady BA, Furth SL, Fadrowski JJ, Atkinson MA.

Pediatr Nephrol. 2018 Nov;33(11):2131-2136. doi: 10.1007/s00467-018-4020-5. Epub 2018 Jul 14.

PMID:
30008129
31.

Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus.

Sivakumar R, Abboud G, Mathews CE, Atkinson MA, Morel L.

Front Immunol. 2018 May 9;9:1053. doi: 10.3389/fimmu.2018.01053. eCollection 2018.

32.

Islet Microvasculature Alterations With Loss of Beta-cells in Patients With Type 1 Diabetes.

Canzano JS, Nasif LH, Butterworth EA, Fu DA, Atkinson MA, Campbell-Thompson M.

J Histochem Cytochem. 2018 May 1:22155418778546. doi: 10.1369/0022155418778546. [Epub ahead of print]

PMID:
29771178
33.

Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience.

Greenbaum CJ, Speake C, Krischer J, Buckner J, Gottlieb PA, Schatz DA, Herold KC, Atkinson MA.

Diabetes. 2018 Jul;67(7):1216-1225. doi: 10.2337/db18-0065. Epub 2018 May 16.

34.

Type 1 Diabetes TrialNet: A Multifaceted Approach to Bringing Disease-Modifying Therapy to Clinical Use in Type 1 Diabetes.

Bingley PJ, Wherrett DK, Shultz A, Rafkin LE, Atkinson MA, Greenbaum CJ.

Diabetes Care. 2018 Apr;41(4):653-661. doi: 10.2337/dc17-0806.

35.

Application of a Genetic Risk Score to Racially Diverse Type 1 Diabetes Populations Demonstrates the Need for Diversity in Risk-Modeling.

Perry DJ, Wasserfall CH, Oram RA, Williams MD, Posgai A, Muir AB, Haller MJ, Schatz DA, Wallet MA, Mathews CE, Atkinson MA, Brusko TM.

Sci Rep. 2018 Mar 14;8(1):4529. doi: 10.1038/s41598-018-22574-5.

36.

Methyldopa blocks MHC class II binding to disease-specific antigens in autoimmune diabetes.

Ostrov DA, Alkanani A, McDaniel KA, Case S, Baschal EE, Pyle L, Ellis S, Pöllinger B, Seidl KJ, Shah VN, Garg SK, Atkinson MA, Gottlieb PA, Michels AW.

J Clin Invest. 2018 May 1;128(5):1888-1902. doi: 10.1172/JCI97739. Epub 2018 Apr 3.

37.

Loss of B-Cell Anergy in Type 1 Diabetes Is Associated With High-Risk HLA and Non-HLA Disease Susceptibility Alleles.

Smith MJ, Rihanek M, Wasserfall C, Mathews CE, Atkinson MA, Gottlieb PA, Cambier JC.

Diabetes. 2018 Apr;67(4):697-703. doi: 10.2337/db17-0937. Epub 2018 Jan 17.

38.

Hospital time prior to death and pancreas histopathology: implications for future studies.

Kusmartseva I, Beery M, Philips T, Selman S, Jadhav P, Wasserfall C, Muller A, Pugliese A, Longmate JA, Schatz DA, Atkinson MA, Kaddis JS.

Diabetologia. 2018 Apr;61(4):954-958. doi: 10.1007/s00125-017-4494-x. Epub 2017 Nov 11.

39.

Transient BAFF Blockade Inhibits Type 1 Diabetes Development in Nonobese Diabetic Mice by Enriching Immunoregulatory B Lymphocytes Sensitive to Deletion by Anti-CD20 Cotherapy.

Wang Q, Racine JJ, Ratiu JJ, Wang S, Ettinger R, Wasserfall C, Atkinson MA, Serreze DV.

J Immunol. 2017 Dec 1;199(11):3757-3770. doi: 10.4049/jimmunol.1700822. Epub 2017 Oct 20.

40.

Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity.

Kemppainen KM, Vehik K, Lynch KF, Larsson HE, Canepa RJ, Simell V, Koletzko S, Liu E, Simell OG, Toppari J, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian WA, She JX, Akolkar B, Schatz DA, Atkinson MA, Blaser MJ, Krischer JP, Hyöty H, Agardh D, Triplett EW; Environmental Determinants of Diabetes in the Young (TEDDY) Study Group.

JAMA Pediatr. 2017 Dec 1;171(12):1217-1225. doi: 10.1001/jamapediatrics.2017.2905.

41.

Disease-specific biases in alternative splicing and tissue-specific dysregulation revealed by multitissue profiling of lymphocyte gene expression in type 1 diabetes.

Newman JRB, Conesa A, Mika M, New FN, Onengut-Gumuscu S, Atkinson MA, Rich SS, McIntyre LM, Concannon P.

Genome Res. 2017 Nov;27(11):1807-1815. doi: 10.1101/gr.217984.116. Epub 2017 Oct 12.

42.

Pancreatic Histopathology of Human Monogenic Diabetes Due to Causal Variants in KCNJ11, HNF1A, GATA6, and LMNA.

Sanyoura M, Jacobsen L, Carmody D, Del Gaudio D, Alkorta-Aranburu G, Arndt K, Hu Y, Kobiernicki F, Kusmartseva I, Atkinson MA, Philipson LH, Schatz D, Campbell-Thompson M, Greeley SAW.

J Clin Endocrinol Metab. 2018 Jan 1;103(1):35-45. doi: 10.1210/jc.2017-01159.

43.

T cells display mitochondria hyperpolarization in human type 1 diabetes.

Chen J, Chernatynskaya AV, Li JW, Kimbrell MR, Cassidy RJ, Perry DJ, Muir AB, Atkinson MA, Brusko TM, Mathews CE.

Sci Rep. 2017 Sep 7;7(1):10835. doi: 10.1038/s41598-017-11056-9.

44.

Type 1 Interferons Potentiate Human CD8+ T-Cell Cytotoxicity Through a STAT4- and Granzyme B-Dependent Pathway.

Newby BN, Brusko TM, Zou B, Atkinson MA, Clare-Salzler M, Mathews CE.

Diabetes. 2017 Dec;66(12):3061-3071. doi: 10.2337/db17-0106. Epub 2017 Sep 6.

45.

Proteoliposome-based full-length ZnT8 self-antigen for type 1 diabetes diagnosis on a plasmonic platform.

Wan H, Merriman C, Atkinson MA, Wasserfall CH, Mcgrail KM, Liang Y, Fu D, Dai H.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10196-10201. doi: 10.1073/pnas.1711169114. Epub 2017 Sep 5.

46.

Dysglycemia and Index60 as Prediagnostic End Points for Type 1 Diabetes Prevention Trials.

Nathan BM, Boulware D, Geyer S, Atkinson MA, Colman P, Goland R, Russell W, Wentworth JM, Wilson DM, Evans-Molina C, Wherrett D, Skyler JS, Moran A, Sosenko JM; Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups.

Diabetes Care. 2017 Nov;40(11):1494-1499. doi: 10.2337/dc17-0916. Epub 2017 Aug 31.

47.

Untargeted metabolomic analysis in naturally occurring canine diabetes mellitus identifies similarities to human Type 1 Diabetes.

O'Kell AL, Garrett TJ, Wasserfall C, Atkinson MA.

Sci Rep. 2017 Aug 25;7(1):9467. doi: 10.1038/s41598-017-09908-5.

48.

Impact of blood collection and processing on peripheral blood gene expression profiling in type 1 diabetes.

Yip L, Fuhlbrigge R, Atkinson MA, Fathman CG.

BMC Genomics. 2017 Aug 18;18(1):636. doi: 10.1186/s12864-017-3949-2.

49.

Visual attention and action: How cueing, direct mapping, and social interactions drive orienting.

Atkinson MA, Simpson AA, Cole GG.

Psychon Bull Rev. 2018 Oct;25(5):1585-1605. doi: 10.3758/s13423-017-1354-0. Review.

PMID:
28808932
50.

Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

Babon JAB, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC.

Nat Med. 2017 Aug 4;23(8):1004. doi: 10.1038/nm0817-1004a. No abstract available.

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