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Items: 36


Comparison of PCR and Viable Count as a Method for Enumeration of Bacteria in an A/J Mouse Aerosol Model of Q Fever.

Hartley MG, Ralph E, Norville IH, Prior JL, Atkins TP.

Front Microbiol. 2019 Jul 16;10:1552. doi: 10.3389/fmicb.2019.01552. eCollection 2019.


Extensive genome analysis of Coxiella burnetii reveals limited evolution within genomic groups.

Hemsley CM, O'Neill PA, Essex-Lopresti A, Norville IH, Atkins TP, Titball RW.

BMC Genomics. 2019 Jun 5;20(1):441. doi: 10.1186/s12864-019-5833-8.


Genome Resequencing of Laboratory Stocks of Burkholderia pseudomallei K96243.

Wagley S, Scott AE, Ireland PM, Prior JL, Atkins TP, Bancroft GJ, Studholme DJ, Titball RW.

Microbiol Resour Announc. 2019 Feb 28;8(9). pii: e01529-18. doi: 10.1128/MRA.01529-18. eCollection 2019 Feb.


An O-Antigen Glycoconjugate Vaccine Produced Using Protein Glycan Coupling Technology Is Protective in an Inhalational Rat Model of Tularemia.

Marshall LE, Nelson M, Davies CH, Whelan AO, Jenner DC, Moule MG, Denman C, Cuccui J, Atkins TP, Wren BW, Prior JL.

J Immunol Res. 2018 Nov 29;2018:8087916. doi: 10.1155/2018/8087916. eCollection 2018.


An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions.

Senior NJ, Sasidharan K, Saint RJ, Scott AE, Sarkar-Tyson M, Ireland PM, Bullifent HL, Rong Yang Z, Moore K, Oyston PCF, Atkins TP, Atkins HS, Soyer OS, Titball RW.

BMC Microbiol. 2017 Jul 21;17(1):163. doi: 10.1186/s12866-017-1073-8.


A Noise Trimming and Positional Significance of Transposon Insertion System to Identify Essential Genes in Yersinia pestis.

Yang ZR, Bullifent HL, Moore K, Paszkiewicz K, Saint RJ, Southern SJ, Champion OL, Senior NJ, Sarkar-Tyson M, Oyston PC, Atkins TP, Titball RW.

Sci Rep. 2017 Feb 6;7:41923. doi: 10.1038/srep41923.


Protection against Experimental Melioidosis with a Synthetic manno-Heptopyranose Hexasaccharide Glycoconjugate.

Scott AE, Christ WJ, George AJ, Stokes MG, Lohman GJ, Guo Y, Jones M, Titball RW, Atkins TP, Campbell AS, Prior JL.

Bioconjug Chem. 2016 Jun 15;27(6):1435-46. doi: 10.1021/acs.bioconjchem.5b00525. Epub 2016 May 17.


Characterization of lesion formation in marmosets following inhalational challenge with different strains of Burkholderia pseudomallei.

Nelson M, Nunez A, Ngugi SA, Sinclair A, Atkins TP.

Int J Exp Pathol. 2015 Dec;96(6):414-26. doi: 10.1111/iep.12161. Epub 2016 Jan 19.


Systematic mutagenesis of genes encoding predicted autotransported proteins of Burkholderia pseudomallei identifies factors mediating virulence in mice, net intracellular replication and a novel protein conferring serum resistance.

Lazar Adler NR, Stevens MP, Dean RE, Saint RJ, Pankhania D, Prior JL, Atkins TP, Kessler B, Nithichanon A, Lertmemongkolchai G, Galyov EE.

PLoS One. 2015 Apr 1;10(4):e0121271. doi: 10.1371/journal.pone.0121271. eCollection 2015.


Comparative experimental subcutaneous glanders and melioidosis in the common marmoset (Callithrix jacchus).

Nelson M, Salguero FJ, Dean RE, Ngugi SA, Smither SJ, Atkins TP, Lever MS.

Int J Exp Pathol. 2014 Dec;95(6):378-91. doi: 10.1111/iep.12105. Epub 2014 Dec 5.


Efficacy of liposome-encapsulated ciprofloxacin in a murine model of Q fever.

Norville IH, Hatch GJ, Bewley KR, Atkinson DJ, Hamblin KA, Blanchard JD, Armstrong SJ, Pitman JK, Rayner E, Hall G, Vipond J, Atkins TP.

Antimicrob Agents Chemother. 2014 Sep;58(9):5510-8. doi: 10.1128/AAC.03443-14. Epub 2014 Jul 7.


Protection against experimental melioidosis following immunisation with a lipopolysaccharide-protein conjugate.

Scott AE, Ngugi SA, Laws TR, Corser D, Lonsdale CL, D'Elia RV, Titball RW, Williamson ED, Atkins TP, Prior JL.

J Immunol Res. 2014;2014:392170. doi: 10.1155/2014/392170. Epub 2014 May 7.


Burkholderia pseudomallei capsular polysaccharide conjugates provide protection against acute melioidosis.

Scott AE, Burtnick MN, Stokes MG, Whelan AO, Williamson ED, Atkins TP, Prior JL, Brett PJ.

Infect Immun. 2014 Aug;82(8):3206-13. doi: 10.1128/IAI.01847-14. Epub 2014 May 27.


Galleria mellonella as an alternative model of Coxiella burnetii infection.

Norville IH, Hartley MG, Martinez E, Cantet F, Bonazzi M, Atkins TP.

Microbiology. 2014 Jun;160(Pt 6):1175-81. doi: 10.1099/mic.0.077230-0. Epub 2014 Mar 27.


Correction: Identification of a Predicted Trimeric Autotransporter Adhesin Required for Biofilm Formation of Burkholderia pseudomallei.

Lazar Adler NR, Dean RE, Saint RJ, Stevens MP, Prior JL, Atkins TP, Galyov EE.

PLoS One. 2014 Jan 9;9(1). doi: 10.1371/annotation/f016476b-5b84-4c9a-899f-fe8b8bc927b5. eCollection 2014.


Identification of a predicted trimeric autotransporter adhesin required for biofilm formation of Burkholderia pseudomallei.

Lazar Adler NR, Dean RE, Saint RJ, Stevens MP, Prior JL, Atkins TP, Galyov EE.

PLoS One. 2013 Nov 5;8(11):e79461. doi: 10.1371/journal.pone.0079461. eCollection 2013. Erratum in: PLoS One. 2014 Jan 9;9(1):.


In vivo manipulation of γ9(+) T cells in the common marmoset (Callithrix Jacchus) with phosphoantigen and effect on the progression of respiratory melioidosis.

Laws TR, Nelson M, Bonnafous C, Sicard H, Taylor C, Salguero FJ, Atkins TP, Oyston PC, Rowland CA.

PLoS One. 2013 Sep 30;8(9):e74789. doi: 10.1371/journal.pone.0074789. eCollection 2013.


Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis.

Cuccui J, Thomas RM, Moule MG, D'Elia RV, Laws TR, Mills DC, Williamson D, Atkins TP, Prior JL, Wren BW.

Open Biol. 2013 May 22;3(5):130002. doi: 10.1098/rsob.130002.


Protection against experimental melioidosis following immunization with live Burkholderia thailandensis expressing a manno-heptose capsule.

Scott AE, Laws TR, D'Elia RV, Stokes MG, Nandi T, Williamson ED, Tan P, Prior JL, Atkins TP.

Clin Vaccine Immunol. 2013 Jul;20(7):1041-7. doi: 10.1128/CVI.00113-13. Epub 2013 May 15.


Trimethoprim/sulfamethoxazole (co-trimoxazole) prophylaxis is effective against acute murine inhalational melioidosis and glanders.

Barnes KB, Steward J, Thwaite JE, Lever MS, Davies CH, Armstrong SJ, Laws TR, Roughley N, Harding SV, Atkins TP, Simpson AJ, Atkins HS.

Int J Antimicrob Agents. 2013 Jun;41(6):552-7. doi: 10.1016/j.ijantimicag.2013.02.007. Epub 2013 Mar 19.


Design and characterization of novel hybrid antimicrobial peptides based on cecropin A, LL-37 and magainin II.

Fox MA, Thwaite JE, Ulaeto DO, Atkins TP, Atkins HS.

Peptides. 2012 Feb;33(2):197-205. doi: 10.1016/j.peptides.2012.01.013. Epub 2012 Jan 24.


Flagellar glycosylation in Burkholderia pseudomallei and Burkholderia thailandensis.

Scott AE, Twine SM, Fulton KM, Titball RW, Essex-Lopresti AE, Atkins TP, Prior JL.

J Bacteriol. 2011 Jul;193(14):3577-87. doi: 10.1128/JB.01385-10. Epub 2011 May 20.


The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei.

Burtnick MN, Brett PJ, Harding SV, Ngugi SA, Ribot WJ, Chantratita N, Scorpio A, Milne TS, Dean RE, Fritz DL, Peacock SJ, Prior JL, Atkins TP, Deshazer D.

Infect Immun. 2011 Apr;79(4):1512-25. doi: 10.1128/IAI.01218-10. Epub 2011 Feb 7.


Lipopolysaccharide from Burkholderia thailandensis E264 provides protection in a murine model of melioidosis.

Ngugi SA, Ventura VV, Qazi O, Harding SV, Kitto GB, Estes DM, Dell A, Titball RW, Atkins TP, Brown KA, Hitchen PG, Prior JL.

Vaccine. 2010 Nov 3;28(47):7551-5. doi: 10.1016/j.vaccine.2010.08.058. Epub 2010 Sep 15.


Protective efficacy of heat-inactivated B. thailandensis, B. mallei or B. pseudomallei against experimental melioidosis and glanders.

Sarkar-Tyson M, Smither SJ, Harding SV, Atkins TP, Titball RW.

Vaccine. 2009 Jul 16;27(33):4447-51. doi: 10.1016/j.vaccine.2009.05.040. Epub 2009 May 31.


Differential cell surface properties of vegetative Bacillus.

Thwaite JE, Laws TR, Atkins TP, Atkins HS.

Lett Appl Microbiol. 2009 Mar;48(3):373-8. doi: 10.1111/j.1472-765X.2008.02543.x. Epub 2009 Feb 2.


Polysaccharides and virulence of Burkholderia pseudomallei.

Sarkar-Tyson M, Thwaite JE, Harding SV, Smither SJ, Oyston PC, Atkins TP, Titball RW.

J Med Microbiol. 2007 Aug;56(Pt 8):1005-10.


Identification of a LolC homologue in Burkholderia pseudomallei, a novel protective antigen for melioidosis.

Harland DN, Chu K, Haque A, Nelson M, Walker NJ, Sarkar-Tyson M, Atkins TP, Moore B, Brown KA, Bancroft G, Titball RW, Atkins HS.

Infect Immun. 2007 Aug;75(8):4173-80. Epub 2007 May 21.


The identification of surface proteins of Burkholderia pseudomallei.

Harding SV, Sarkar-Tyson M, Smither SJ, Atkins TP, Oyston PC, Brown KA, Liu Y, Wait R, Titball RW.

Vaccine. 2007 Mar 30;25(14):2664-72. Epub 2006 Dec 26.


Global map of growth-regulated gene expression in Burkholderia pseudomallei, the causative agent of melioidosis.

Rodrigues F, Sarkar-Tyson M, Harding SV, Sim SH, Chua HH, Lin CH, Han X, Karuturi RK, Sung K, Yu K, Chen W, Atkins TP, Titball RW, Tan P.

J Bacteriol. 2006 Dec;188(23):8178-88. Epub 2006 Sep 22.


Proteolytic degradation of human antimicrobial peptide LL-37 by Bacillus anthracis may contribute to virulence.

Thwaite JE, Hibbs S, Titball RW, Atkins TP.

Antimicrob Agents Chemother. 2006 Jul;50(7):2316-22.


The pathogen Pseudomonas aeruginosa negatively affects the attraction response of the nematode Caenorhabditis elegans to bacteria.

Laws TR, Atkins HS, Atkins TP, Titball RW.

Microb Pathog. 2006 Jun;40(6):293-7. Epub 2006 May 6.


The nematode Panagrellus redivivus is susceptible to killing by human pathogens at 37 degrees C.

Laws TR, Smith SA, Smith MP, Harding SV, Atkins TP, Titball RW.

FEMS Microbiol Lett. 2005 Sep 1;250(1):77-83.


Evaluation of lipopolysaccharide and capsular polysaccharide as subunit vaccines against experimental melioidosis.

Nelson M, Prior JL, Lever MS, Jones HE, Atkins TP, Titball RW.

J Med Microbiol. 2004 Dec;53(Pt 12):1177-82.


Age influences resistance of Caenorhabditis elegans to killing by pathogenic bacteria.

Laws TR, Harding SV, Smith MP, Atkins TP, Titball RW.

FEMS Microbiol Lett. 2004 May 15;234(2):281-7.


A liquid-based method for the assessment of bacterial pathogenicity using the nematode Caenorhabditis elegans.

Smith MP, Laws TR, Atkins TP, Oyston PC, de Pomerai DI, Titball RW.

FEMS Microbiol Lett. 2002 May 7;210(2):181-5.

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