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Items: 36

1.

The Role of p38 MAPK in Triacylglycerol Accumulation during Apoptosis.

Li N, Saitou M, Atilla-Gokcumen GE.

Proteomics. 2019 Jul;19(13):e1900160. doi: 10.1002/pmic.201900160. Epub 2019 Jun 24.

PMID:
31099964
2.

Applications of metabolomics in assessing ecological effects of emerging contaminants and pollutants on plants.

Matich EK, Chavez Soria NG, Aga DS, Atilla-Gokcumen GE.

J Hazard Mater. 2019 Jul 5;373:527-535. doi: 10.1016/j.jhazmat.2019.02.084. Epub 2019 Mar 21. Review.

PMID:
30951997
3.

Removal of Serum Lipids and Lipid-Derived Metabolites to Investigate Breast Cancer Cell Biology.

Brovkovych V, Aldrich A, Li N, Atilla-Gokcumen GE, Frasor J.

Proteomics. 2019 Mar 27:e1800370. doi: 10.1002/pmic.201800370. [Epub ahead of print]

PMID:
30919589
4.

Lipidomics reveals insights on the biological effects of copper oxide nanoparticles in a human colon carcinoma cell line.

Chavez Soria NG, Aga DS, Atilla-Gokcumen GE.

Mol Omics. 2019 Feb 11;15(1):30-38. doi: 10.1039/c8mo00162f.

PMID:
30560257
5.

Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion.

Wang SS, Gao X, Solar VD, Yu X, Antonopoulos A, Friedman AE, Matich EK, Atilla-Gokcumen GE, Nasirikenari M, Lau JT, Dell A, Haslam SM, Laine RA, Matta KL, Neelamegham S.

Cell Chem Biol. 2018 Dec 20;25(12):1519-1532.e5. doi: 10.1016/j.chembiol.2018.09.012. Epub 2018 Oct 18.

PMID:
30344053
6.

Fatostatin induces pro- and anti-apoptotic lipid accumulation in breast cancer.

Brovkovych V, Izhar Y, Danes JM, Dubrovskyi O, Sakallioglu IT, Morrow LM, Atilla-Gokcumen GE, Frasor J.

Oncogenesis. 2018 Aug 24;7(8):66. doi: 10.1038/s41389-018-0076-0.

7.

Mass spectrometry based detection of common vitellogenin peptides across fish species for assessing exposure to estrogenic compounds in aquatic environments.

He P, Matich EK, Yonkos LT, Friedman AE, Atilla-Gokcumen GE, Aga DS.

Sci Total Environ. 2019 Jan 1;646:400-408. doi: 10.1016/j.scitotenv.2018.07.252. Epub 2018 Jul 26.

PMID:
30055500
8.

An evolutionary transcriptomics approach links CD36 to membrane remodeling in replicative senescence.

Saitou M, Lizardo DY, Taskent RO, Millner A, Gokcumen O, Atilla-Gokcumen GE.

Mol Omics. 2018 Aug 6;14(4):237-246. doi: 10.1039/c8mo00099a.

PMID:
29974107
9.

CBR1 rs9024 genotype status impacts the bioactivation of loxoprofen in human liver.

Quiñones-Lombraña A, Li N, Del Solar V, Atilla-Gokcumen GE, Blanco JG.

Biopharm Drug Dispos. 2018 Jun;39(6):315-318. doi: 10.1002/bdd.2135.

10.

Time-series lipidomic analysis of the oleaginous green microalga species Ettlia oleoabundans under nutrient stress.

Matich EK, Ghafari M, Camgoz E, Caliskan E, Pfeifer BA, Haznedaroglu BZ, Atilla-Gokcumen GE.

Biotechnol Biofuels. 2018 Feb 6;11:29. doi: 10.1186/s13068-018-1026-y. eCollection 2018.

11.

Turning the Spotlight on Lipids in Non-Apoptotic Cell Death.

Parisi LR, Morrow LM, Visser MB, Atilla-Gokcumen GE.

ACS Chem Biol. 2018 Mar 16;13(3):506-515. doi: 10.1021/acschembio.7b01082. Epub 2018 Feb 6. Review.

PMID:
29376324
12.

A Protective Role for Triacylglycerols during Apoptosis.

Li N, Sancak Y, Frasor J, Atilla-Gokcumen GE.

Biochemistry. 2018 Jan 9;57(1):72-80. doi: 10.1021/acs.biochem.7b00975. Epub 2017 Dec 13.

13.

Very Long Chain Fatty Acids Are Functionally Involved in Necroptosis.

Parisi LR, Li N, Atilla-Gokcumen GE.

Cell Chem Biol. 2017 Dec 21;24(12):1445-1454.e8. doi: 10.1016/j.chembiol.2017.08.026. Epub 2017 Oct 12.

14.

Noncanonical Roles of Lipids in Different Cellular Fates.

Lizardo DY, Parisi LR, Li N, Atilla-Gokcumen GE.

Biochemistry. 2018 Jan 9;57(1):22-29. doi: 10.1021/acs.biochem.7b00862. Epub 2017 Oct 24. Review.

PMID:
29019646
15.

Vessel-Targeted Chemophototherapy with Cationic Porphyrin-Phospholipid Liposomes.

Luo D, Geng J, Li N, Carter KA, Shao S, Atilla-Gokcumen GE, Lovell JF.

Mol Cancer Ther. 2017 Nov;16(11):2452-2461. doi: 10.1158/1535-7163.MCT-17-0276. Epub 2017 Jul 20.

16.

Multifunctional Liposomes for Image-Guided Intratumoral Chemo-Phototherapy.

Miranda D, Carter K, Luo D, Shao S, Geng J, Li C, Chitgupi U, Turowski SG, Li N, Atilla-Gokcumen GE, Spernyak JA, Lovell JF.

Adv Healthc Mater. 2017 Aug;6(16). doi: 10.1002/adhm.201700253. Epub 2017 May 15.

17.

Regulation of lipids is central to replicative senescence.

Lizardo DY, Lin YL, Gokcumen O, Atilla-Gokcumen GE.

Mol Biosyst. 2017 Feb 28;13(3):498-509. doi: 10.1039/c6mb00842a.

PMID:
28128379
18.

Specific Triacylglycerols Accumulate via Increased Lipogenesis During 5-FU-Induced Apoptosis.

Li N, Lizardo DY, Atilla-Gokcumen GE.

ACS Chem Biol. 2016 Sep 16;11(9):2583-7. doi: 10.1021/acschembio.6b00410. Epub 2016 Jul 27.

PMID:
27428610
19.

Rapid Light-Triggered Drug Release in Liposomes Containing Small Amounts of Unsaturated and Porphyrin-Phospholipids.

Luo D, Li N, Carter KA, Lin C, Geng J, Shao S, Huang WC, Qin Y, Atilla-Gokcumen GE, Lovell JF.

Small. 2016 Jun;12(22):3039-47. doi: 10.1002/smll.201503966. Epub 2016 Apr 28.

20.

Glycosphingolipids on Human Myeloid Cells Stabilize E-Selectin-Dependent Rolling in the Multistep Leukocyte Adhesion Cascade.

Mondal N, Stolfa G, Antonopoulos A, Zhu Y, Wang SS, Buffone A Jr, Atilla-Gokcumen GE, Haslam SM, Dell A, Neelamegham S.

Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):718-27. doi: 10.1161/ATVBAHA.115.306748. Epub 2016 Feb 11.

21.

Differential Regulation of Specific Sphingolipids in Colon Cancer Cells during Staurosporine-Induced Apoptosis.

del Solar V, Lizardo DY, Li N, Hurst JJ, Brais CJ, Atilla-Gokcumen GE.

Chem Biol. 2015 Dec 17;22(12):1662-70. doi: 10.1016/j.chembiol.2015.11.004.

22.

Effects of Polyhexamethylene Biguanide and Polyquaternium-1 on Phospholipid Bilayer Structure and Dynamics.

Horner IJ, Kraut ND, Hurst JJ, Rook AM, Collado CM, Atilla-Gokcumen GE, Maziarz EP, Liu XM, Merchea MM, Bright FV.

J Phys Chem B. 2015 Aug 20;119(33):10531-42. doi: 10.1021/acs.jpcb.5b07162. Epub 2015 Aug 7.

PMID:
26239890
23.

Application of metabolite profiling tools and time-of-flight mass spectrometry in the identification of transformation products of iopromide and iopamidol during advanced oxidation.

Singh RR, Lester Y, Linden KG, Love NG, Atilla-Gokcumen GE, Aga DS.

Environ Sci Technol. 2015 Mar 3;49(5):2983-90. doi: 10.1021/es505469h. Epub 2015 Feb 17.

PMID:
25651339
24.

A comparative LC-MS based profiling approach to analyze lipid composition in tissue culture systems.

Atilla-Gokcumen GE, Eggert US.

Methods Mol Biol. 2015;1232:103-13. doi: 10.1007/978-1-4939-1752-5_9.

PMID:
25331131
25.

Lipids in cell biology: how can we understand them better?

Muro E, Atilla-Gokcumen GE, Eggert US.

Mol Biol Cell. 2014 Jun 15;25(12):1819-23. doi: 10.1091/mbc.E13-09-0516.

26.

Dividing cells regulate their lipid composition and localization.

Atilla-Gokcumen GE, Muro E, Relat-Goberna J, Sasse S, Bedigian A, Coughlin ML, Garcia-Manyes S, Eggert US.

Cell. 2014 Jan 30;156(3):428-39. doi: 10.1016/j.cell.2013.12.015. Epub 2014 Jan 23.

27.

Inhibition of glycosphingolipid biosynthesis induces cytokinesis failure.

Atilla-Gokcumen GE, Bedigian AV, Sasse S, Eggert US.

J Am Chem Soc. 2011 Jul 6;133(26):10010-3. doi: 10.1021/ja202804b. Epub 2011 Jun 14.

28.

Structurally sophisticated octahedral metal complexes as highly selective protein kinase inhibitors.

Feng L, Geisselbrecht Y, Blanck S, Wilbuer A, Atilla-Gokcumen GE, Filippakopoulos P, Kräling K, Celik MA, Harms K, Maksimoska J, Marmorstein R, Frenking G, Knapp S, Essen LO, Meggers E.

J Am Chem Soc. 2011 Apr 20;133(15):5976-86. doi: 10.1021/ja1112996. Epub 2011 Mar 29.

29.

Structure of anticancer ruthenium half-sandwich complex bound to glycogen synthase kinase 3β.

Atilla-Gokcumen GE, Di Costanzo L, Meggers E.

J Biol Inorg Chem. 2011 Jan;16(1):45-50. doi: 10.1007/s00775-010-0699-x. Epub 2010 Sep 7.

PMID:
20821241
30.

Inert ruthenium half-sandwich complexes with anticancer activity.

Meggers E, Atilla-Gokcumen GE, Gründler K, Frias C, Prokop A.

Dalton Trans. 2009 Dec 28;(48):10882-8. doi: 10.1039/b917792b. Epub 2009 Nov 2.

PMID:
20023918
31.

Making the cut: the chemical biology of cytokinesis.

Atilla-Gokcumen GE, Castoreno AB, Sasse S, Eggert US.

ACS Chem Biol. 2010 Jan 15;5(1):79-90. doi: 10.1021/cb900256m. Review.

32.

Extremely tight binding of a ruthenium complex to glycogen synthase kinase 3.

Atilla-Gokcumen GE, Pagano N, Streu C, Maksimoska J, Filippakopoulos P, Knapp S, Meggers E.

Chembiochem. 2008 Dec 15;9(18):2933-6. doi: 10.1002/cbic.200800489. No abstract available.

33.

Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity.

Xie P, Williams DS, Atilla-Gokcumen GE, Milk L, Xiao M, Smalley KS, Herlyn M, Meggers E, Marmorstein R.

ACS Chem Biol. 2008 May 16;3(5):305-16. doi: 10.1021/cb800039y.

34.

Similar biological activities of two isostructural ruthenium and osmium complexes.

Maksimoska J, Williams DS, Atilla-Gokcumen GE, Smalley KS, Carroll PJ, Webster RD, Filippakopoulos P, Knapp S, Herlyn M, Meggers E.

Chemistry. 2008;14(16):4816-22. doi: 10.1002/chem.200800294.

35.

An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells.

Smalley KS, Contractor R, Haass NK, Kulp AN, Atilla-Gokcumen GE, Williams DS, Bregman H, Flaherty KT, Soengas MS, Meggers E, Herlyn M.

Cancer Res. 2007 Jan 1;67(1):209-17.

36.

Organometallic compounds with biological activity: a very selective and highly potent cellular inhibitor for glycogen synthase kinase 3.

Atilla-Gokcumen GE, Williams DS, Bregman H, Pagano N, Meggers E.

Chembiochem. 2006 Sep;7(9):1443-50.

PMID:
16858717

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