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Premature deaths due to head and neck cancers in canada: A nationwide analysis from 1980 to 2010.

Atchison KM, Pham TM, Sikdar KC, Weeks LA, Karosas APV, Sinnarajah A, Dort JC, Cheung WY, Shack L.

Laryngoscope. 2019 Apr 25. doi: 10.1002/lary.28024. [Epub ahead of print]


Oral Health Literacy, Preventive Behavior Measures, and Chronic Medical Conditions.

Messadi DV, Macek MD, Markovic D, Atchison KA.

JDR Clin Trans Res. 2018 Jul;3(3):288-301. doi: 10.1177/2380084418769835. Epub 2018 Apr 17.


Bridging the dental-medical divide: Case studies integrating oral health care and primary health care.

Atchison KA, Weintraub JA, Rozier RG.

J Am Dent Assoc. 2018 Oct;149(10):850-858. doi: 10.1016/j.adaj.2018.05.030. Epub 2018 Jul 26.


Integrating Oral Health and Primary Care in the Changing Health Care Landscape.

Atchison KA, Weintraub JA.

N C Med J. 2017 Nov-Dec;78(6):406-409. doi: 10.18043/ncm.78.6.406.


The value of a combined word recognition and knowledge measure to understand characteristics of our patients' oral health literacy.

Atchison KA, Macek MD, Markovic D.

Community Dent Oral Epidemiol. 2017 Aug;45(4):380-388. doi: 10.1111/cdoe.12301. Epub 2017 Apr 26.


Oral health conceptual knowledge and its relationships with oral health outcomes: Findings from a Multi-site Health Literacy Study.

Macek MD, Atchison KA, Chen H, Wells W, Haynes D, Parker RM, Azzo S.

Community Dent Oral Epidemiol. 2017 Aug;45(4):323-329. doi: 10.1111/cdoe.12294. Epub 2017 Mar 7.


Did you know Medicare does not usually include a dental benefit? Findings from a multisite investigation of oral health literacy.

Macek MD, Atchison KA, Wells W, Haynes D, Parker RM, Chen H.

J Public Health Dent. 2017 Mar;77(2):95-98. doi: 10.1111/jphd.12199. Epub 2017 Jan 12.


Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality.

Butler CR, Ogilvie K, Martinez-Alsina L, Barreiro G, Beck EM, Nolan CE, Atchison K, Benvenuti E, Buzon L, Doran S, Gonzales C, Helal CJ, Hou X, Hsu MH, Johnson EF, Lapham K, Lanyon L, Parris K, O'Neill BT, Riddell D, Robshaw A, Vajdos F, Brodney MA.

J Med Chem. 2017 Jan 12;60(1):386-402. doi: 10.1021/acs.jmedchem.6b01451. Epub 2016 Dec 20.


Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors.

Zuhl AM, Nolan CE, Brodney MA, Niessen S, Atchison K, Houle C, Karanian DA, Ambroise C, Brulet JW, Beck EM, Doran SD, O'Neill BT, Am Ende CW, Chang C, Geoghegan KF, West GM, Judkins JC, Hou X, Riddell DR, Johnson DS.

Nat Commun. 2016 Oct 11;7:13042. doi: 10.1038/ncomms13042.


Comparing Well-Tested Health Literacy Measures for Oral Health: A Pilot Assessment.

Aldoory L, Macek MD, Atchison KA, Chen H.

J Health Commun. 2016 Nov;21(11):1161-1169. Epub 2016 Oct 11.


Oral Health Literacy and Measures of Periodontal Disease.

Holtzman JS, Atchison KA, Macek MD, Markovic D.

J Periodontol. 2017 Jan;88(1):78-88. Epub 2016 Aug 13.


Assessing health literacy and oral health: preliminary results of a multi-site investigation.

Macek MD, Atchison KA, Watson MR, Holtzman J, Wells W, Braun B, Aldoory L, Messadi D, Gironda M, Haynes D, Parker RM, Chen H, Coller S, Richards J.

J Public Health Dent. 2016 Sep;76(4):303-313. doi: 10.1111/jphd.12156. Epub 2016 Apr 29.


Developing core dental public health competencies for predoctoral dental and dental hygiene students.

Mascarenhas AK, Atchison KA.

J Public Health Dent. 2015 Fall;75 Suppl 1:S6-11. doi: 10.1111/jphd.12129.


Pilot testing a predoctoral dental public health curriculum: reporting process and outcomes.

Bhoopathi V, Atchison KA.

J Public Health Dent. 2015 Fall;75 Suppl 1:S25-32. doi: 10.1111/jphd.12125.


Developing a flexible core Dental Public Health curriculum for predoctoral dental and dental hygiene schools.

Atchison K, Mascarenhas AK, Bhoopathi V.

J Public Health Dent. 2015 Fall;75 Suppl 1:S12-24. doi: 10.1111/jphd.12130.


The association of patients' oral health literacy and dental school communication tools: a pilot study.

Tam A, Yue O, Atchison KA, Richards JK, Holtzman JS.

J Dent Educ. 2015 May;79(5):530-8.


Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors.

Brodney MA, Beck EM, Butler CR, Barreiro G, Johnson EF, Riddell D, Parris K, Nolan CE, Fan Y, Atchison K, Gonzales C, Robshaw AE, Doran SD, Bundesmann MW, Buzon L, Dutra J, Henegar K, LaChapelle E, Hou X, Rogers BN, Pandit J, Lira R, Martinez-Alsina L, Mikochik P, Murray JC, Ogilvie K, Price L, Sakya SM, Yu A, Zhang Y, O'Neill BT.

J Med Chem. 2015 Apr 9;58(7):3223-52. doi: 10.1021/acs.jmedchem.5b00191. Epub 2015 Apr 1.


Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug design.

Butler CR, Brodney MA, Beck EM, Barreiro G, Nolan CE, Pan F, Vajdos F, Parris K, Varghese AH, Helal CJ, Lira R, Doran SD, Riddell DR, Buzon LM, Dutra JK, Martinez-Alsina LA, Ogilvie K, Murray JC, Young JM, Atchison K, Robshaw A, Gonzales C, Wang J, Zhang Y, O'Neill BT.

J Med Chem. 2015 Mar 26;58(6):2678-702. doi: 10.1021/jm501833t. Epub 2015 Mar 9.


Alternative method of oral administration by peanut butter pellet formulation results in target engagement of BACE1 and attenuation of gavage-induced stress responses in mice.

Gonzales C, Zaleska MM, Riddell DR, Atchison KP, Robshaw A, Zhou H, Sukoff Rizzo SJ.

Pharmacol Biochem Behav. 2014 Nov;126:28-35. doi: 10.1016/j.pbb.2014.08.010. Epub 2014 Sep 19.


The association between oral health literacy and failed appointments in adults attending a university-based general dental clinic.

Holtzman JS, Atchison KA, Gironda MW, Radbod R, Gornbein J.

Community Dent Oral Epidemiol. 2014 Jun;42(3):263-70. doi: 10.1111/cdoe.12089. Epub 2013 Dec 24.


Effects of the γ-secretase inhibitor semagacestat on hippocampal neuronal network oscillation.

Hajós M, Morozova E, Siok C, Atchison K, Nolan CE, Riddell D, Kiss T, Hajós-Korcsok E.

Front Pharmacol. 2013 Jun 14;4:72. doi: 10.3389/fphar.2013.00072. eCollection 2013.


Impact of cone-beam computed tomography on orthodontic diagnosis and treatment planning.

Hodges RJ, Atchison KA, White SC.

Am J Orthod Dentofacial Orthop. 2013 May;143(5):665-74. doi: 10.1016/j.ajodo.2012.12.011.


A brief 20-item dental/medical health literacy screen (REALMD-20).

Gironda M, Der-Martirosian C, Messadi D, Holtzman J, Atchison K.

J Public Health Dent. 2013 Winter;73(1):50-5. doi: 10.1111/jphd.12005. Epub 2013 Jan 7.


Dentition, dental health habits, and dementia: the Leisure World Cohort Study.

Paganini-Hill A, White SC, Atchison KA.

J Am Geriatr Soc. 2012 Aug;60(8):1556-63. doi: 10.1111/j.1532-5415.2012.04064.x. Epub 2012 Aug 2.


Application of the bicyclo[1.1.1]pentane motif as a nonclassical phenyl ring bioisostere in the design of a potent and orally active γ-secretase inhibitor.

Stepan AF, Subramanyam C, Efremov IV, Dutra JK, O'Sullivan TJ, DiRico KJ, McDonald WS, Won A, Dorff PH, Nolan CE, Becker SL, Pustilnik LR, Riddell DR, Kauffman GW, Kormos BL, Zhang L, Lu Y, Capetta SH, Green ME, Karki K, Sibley E, Atchison KP, Hallgren AJ, Oborski CE, Robshaw AE, Sneed B, O'Donnell CJ.

J Med Chem. 2012 Apr 12;55(7):3414-24. doi: 10.1021/jm300094u. Epub 2012 Mar 29.


Age-dependent disruption in hippocampal θ oscillation in amyloid-β overproducing transgenic mice.

Scott L, Feng J, Kiss T, Needle E, Atchison K, Kawabe TT, Milici AJ, Hajós-Korcsok E, Riddell D, Hajós M.

Neurobiol Aging. 2012 Jul;33(7):1481.e13-23. doi: 10.1016/j.neurobiolaging.2011.12.010. Epub 2012 Jan 9.


Metabolism-directed design of oxetane-containing arylsulfonamide derivatives as γ-secretase inhibitors.

Stepan AF, Karki K, McDonald WS, Dorff PH, Dutra JK, Dirico KJ, Won A, Subramanyam C, Efremov IV, O'Donnell CJ, Nolan CE, Becker SL, Pustilnik LR, Sneed B, Sun H, Lu Y, Robshaw AE, Riddell D, O'Sullivan TJ, Sibley E, Capetta S, Atchison K, Hallgren AJ, Miller E, Wood A, Obach RS.

J Med Chem. 2011 Nov 24;54(22):7772-83. doi: 10.1021/jm200893p. Epub 2011 Oct 26.


Quantitative pharmacokinetic/pharmacodynamic analyses suggest that the 129/SVE mouse is a suitable preclinical pharmacology model for identifying small-molecule γ-secretase inhibitors.

Lu Y, Zhang L, Nolan CE, Becker SL, Atchison K, Robshaw AE, Pustilnik LR, Osgood SM, Miller EH, Stepan AF, Subramanyam C, Efremov I, Hallgren AJ, Riddell D.

J Pharmacol Exp Ther. 2011 Dec;339(3):922-34. doi: 10.1124/jpet.111.186791. Epub 2011 Sep 19.


Dental health behaviors, dentition, and mortality in the elderly: the leisure world cohort study.

Paganini-Hill A, White SC, Atchison KA.

J Aging Res. 2011;2011:156061. doi: 10.4061/2011/156061. Epub 2011 Jun 15.


Comparison of extramural clinical rotation days: did the Pipeline program make a difference?

Atchison KA, Thind A, Carreon DC, Nakazono TT, Gutierrez JJ, Afifi AA, Andersen RM.

J Dent Educ. 2011 Jan;75(1):52-61.


Predictors of risk tolerance among oral surgery patients.

Atchison KA, Der-Martirosian C, Belin TR, Black EE, Gironda MW.

J Oral Maxillofac Surg. 2010 Dec;68(12):2947-54. doi: 10.1016/j.joms.2010.03.002. Epub 2010 Aug 3.


Screening for oral health literacy in an urban dental clinic.

Atchison KA, Gironda MW, Messadi D, Der-Martirosian C.

J Public Health Dent. 2010 Fall;70(4):269-75. doi: 10.1111/j.1752-7325.2010.00181.x.


Predictors of treatment preference for mandibular fracture.

Der-Martirosian C, Gironda MW, Black EE, Belin TR, Atchison KA.

J Public Health Dent. 2010 Winter;70(1):13-8. doi: 10.1111/j.1752-7325.2009.00138.x.


Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.

Martone RL, Zhou H, Atchison K, Comery T, Xu JZ, Huang X, Gong X, Jin M, Kreft A, Harrison B, Mayer SC, Aschmies S, Gonzales C, Zaleska MM, Riddell DR, Wagner E, Lu P, Sun SC, Sonnenberg-Reines J, Oganesian A, Adkins K, Leach MW, Clarke DW, Huryn D, Abou-Gharbia M, Magolda R, Bard J, Frick G, Raje S, Forlow SB, Balliet C, Burczynski ME, Reinhart PH, Wan HI, Pangalos MN, Jacobsen JS.

J Pharmacol Exp Ther. 2009 Nov;331(2):598-608. doi: 10.1124/jpet.109.152975. Epub 2009 Aug 11.


3D timelapse analysis of muscle satellite cell motility.

Siegel AL, Atchison K, Fisher KE, Davis GE, Cornelison DD.

Stem Cells. 2009 Oct;27(10):2527-38. doi: 10.1002/stem.178.


Synthesis and structure-activity relationship of a novel series of heterocyclic sulfonamide gamma-secretase inhibitors.

Pu J, Kreft AF, Aschmies SH, Atchison KP, Berkowitz J, Caggiano TJ, Chlenov M, Diamantidis G, Harrison BL, Hu Y, Huryn D, Steven Jacobsen J, Jin M, Lipinski K, Lu P, Martone RL, Morris K, Sonnenberg-Reines J, Riddell DR, Sabalski J, Sun SC, Wagner E, Wang Y, Xu Z, Zhou H, Resnick L.

Bioorg Med Chem. 2009 Jul 1;17(13):4708-17. doi: 10.1016/j.bmc.2009.04.052. Epub 2009 May 3.


The Pipeline program at Howard University College of Dentistry.

Andersen RM, Atchison KA, Hewlett ER, Grant-Mills D.

J Dent Educ. 2009 Feb;73(2 Suppl):S70-81; discussion S81-2. No abstract available.


Summary and implications of the Dental Pipeline program evaluation.

Andersen RM, Davidson PL, Atchison KA, Crall JJ, Friedman JA, Hewlett ER, Thind A.

J Dent Educ. 2009 Feb;73(2 Suppl):S319-30. No abstract available.


Sustainability of dental school recruitment, curriculum, and community-based Pipeline initiatives.

Thind A, Atchison KA, Nakazono TT, Gutierrez JJ, Carreon DC, Bai J.

J Dent Educ. 2009 Feb;73(2 Suppl):S297-307. No abstract available.


Community-based clinical dental education: effects of the Pipeline program.

Atchison KA, Thind A, Nakazono TT, Wong D, Gutierrez JJ, Carreon DC, Andersen RM.

J Dent Educ. 2009 Feb;73(2 Suppl):S269-82. No abstract available.


The Pipeline program at the University of California, San Francisco, School of Dentistry.

Hewlett ER, Andersen RM, Atchison KA, Bird W.

J Dent Educ. 2009 Feb;73(2 Suppl):S199-209; discussion 210. No abstract available.


The Pipeline program at Loma Linda University School of Dentistry.

Crall JJ, Friedman JA, Atchison KA, Goodacre CJ.

J Dent Educ. 2009 Feb;73(2 Suppl):S175-85; discussion S185. No abstract available.


The Pipeline program at West VIrginia University School of Dentistry.

Friedman JA, Hewlett ER, Atchison KA, Price SS.

J Dent Educ. 2009 Feb;73(2 Suppl):S161-72; discussion S173-4. No abstract available.


The Pipeline program at the University of Washington School of Dentistry.

Atchison KA, Friedman JA, Freed JR, Jackson D.

J Dent Educ. 2009 Feb;73(2 Suppl):S148-59; discussion S159-60. No abstract available.


The Pipeline program at the University of North Carolina at Chapel Hill School of Dentistry.

Hewlett ER, Andersen RM, Atchison KA, Strauss RP.

J Dent Educ. 2009 Feb;73(2 Suppl):S135-45; discussion S145-7. No abstract available.


The Pipeline program at the University of Illinois at Chicago College of Dentistry.

Atchison KA, Hewlett ER, Friedman JA, Evans CA, Bolden AJ, Hryhorczuk C.

J Dent Educ. 2009 Feb;73(2 Suppl):S120-132; discussion S132-4. No abstract available.


Predictors of depressive symptoms following mandibular fracture repair.

Gironda MW, Der-Martirosian C, Belin TR, Black EE, Atchison KA.

J Oral Maxillofac Surg. 2009 Feb;67(2):328-34. doi: 10.1016/j.joms.2008.06.007.


(S)-N-(5-Chlorothiophene-2-sulfonyl)-beta,beta-diethylalaninol a Notch-1-sparing gamma-secretase inhibitor.

Cole DC, Stock JR, Kreft AF, Antane M, Aschmies SH, Atchison KP, Casebier DS, Comery TA, Diamantidis G, Ellingboe JW, Harrison BL, Hu Y, Jin M, Kubrak DM, Lu P, Mann CW, Martone RL, Moore WJ, Oganesian A, Riddell DR, Sonnenberg-Reines J, Sun SC, Wagner E, Wang Z, Woller KR, Xu Z, Zhou H, Jacobsen JS.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):926-9. doi: 10.1016/j.bmcl.2008.11.116. Epub 2008 Dec 6.


Reforming dental education: faculty members' perceptions on the continuation of pipeline program changes.

Thind A, Atchison KA, Andersen RM, Nakazono TT, Gutierrez JJ.

J Dent Educ. 2008 Dec;72(12):1472-80.


Discovery of begacestat, a Notch-1-sparing gamma-secretase inhibitor for the treatment of Alzheimer's disease.

Mayer SC, Kreft AF, Harrison B, Abou-Gharbia M, Antane M, Aschmies S, Atchison K, Chlenov M, Cole DC, Comery T, Diamantidis G, Ellingboe J, Fan K, Galante R, Gonzales C, Ho DM, Hoke ME, Hu Y, Huryn D, Jain U, Jin M, Kremer K, Kubrak D, Lin M, Lu P, Magolda R, Martone R, Moore W, Oganesian A, Pangalos MN, Porte A, Reinhart P, Resnick L, Riddell DR, Sonnenberg-Reines J, Stock JR, Sun SC, Wagner E, Wang T, Woller K, Xu Z, Zaleska MM, Zeldis J, Zhang M, Zhou H, Jacobsen JS.

J Med Chem. 2008 Dec 11;51(23):7348-51. doi: 10.1021/jm801252w.


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