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Items: 1 to 50 of 129

1.

IL-10 produced by macrophages regulates epithelial integrity in the small intestine.

Morhardt TL, Hayashi A, Ochi T, Quirós M, Kitamoto S, Nagao-Kitamoto H, Kuffa P, Atarashi K, Honda K, Kao JY, Nusrat A, Kamada N.

Sci Rep. 2019 Feb 4;9(1):1223. doi: 10.1038/s41598-018-38125-x.

2.

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity.

Tanoue T, Morita S, Plichta DR, Skelly AN, Suda W, Sugiura Y, Narushima S, Vlamakis H, Motoo I, Sugita K, Shiota A, Takeshita K, Yasuma-Mitobe K, Riethmacher D, Kaisho T, Norman JM, Mucida D, Suematsu M, Yaguchi T, Bucci V, Inoue T, Kawakami Y, Olle B, Roberts B, Hattori M, Xavier RJ, Atarashi K, Honda K.

Nature. 2019 Jan;565(7741):600-605. doi: 10.1038/s41586-019-0878-z. Epub 2019 Jan 23.

PMID:
30675064
3.

Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis.

Nakamoto N, Sasaki N, Aoki R, Miyamoto K, Suda W, Teratani T, Suzuki T, Koda Y, Chu PS, Taniki N, Yamaguchi A, Kanamori M, Kamada N, Hattori M, Ashida H, Sakamoto M, Atarashi K, Narushima S, Yoshimura A, Honda K, Sato T, Kanai T.

Nat Microbiol. 2019 Mar;4(3):492-503. doi: 10.1038/s41564-018-0333-1. Epub 2019 Jan 14.

PMID:
30643240
4.

Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia.

Namkoong H, Ishii M, Fujii H, Yagi K, Asami T, Asakura T, Suzuki S, Hegab AE, Kamata H, Tasaka S, Atarashi K, Nakamoto N, Iwata S, Honda K, Kanai T, Hasegawa N, Koyasu S, Betsuyaku T.

PLoS Pathog. 2018 Apr 5;14(4):e1006955. doi: 10.1371/journal.ppat.1006955. eCollection 2018 Apr.

5.

Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation.

Atarashi K, Suda W, Luo C, Kawaguchi T, Motoo I, Narushima S, Kiguchi Y, Yasuma K, Watanabe E, Tanoue T, Thaiss CA, Sato M, Toyooka K, Said HS, Yamagami H, Rice SA, Gevers D, Johnson RC, Segre JA, Chen K, Kolls JK, Elinav E, Morita H, Xavier RJ, Hattori M, Honda K.

Science. 2017 Oct 20;358(6361):359-365. doi: 10.1126/science.aan4526.

6.

Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring.

Kim S, Kim H, Yim YS, Ha S, Atarashi K, Tan TG, Longman RS, Honda K, Littman DR, Choi GB, Huh JR.

Nature. 2017 Sep 28;549(7673):528-532. doi: 10.1038/nature23910. Epub 2017 Sep 13.

7.

Clinical impact of pre-transplant gut microbial diversity on outcomes of allogeneic hematopoietic stem cell transplantation.

Doki N, Suyama M, Sasajima S, Ota J, Igarashi A, Mimura I, Morita H, Fujioka Y, Sugiyama D, Nishikawa H, Shimazu Y, Suda W, Takeshita K, Atarashi K, Hattori M, Sato E, Watakabe-Inamoto K, Yoshioka K, Najima Y, Kobayashi T, Kakihana K, Takahashi N, Sakamaki H, Honda K, Ohashi K.

Ann Hematol. 2017 Sep;96(9):1517-1523. doi: 10.1007/s00277-017-3069-8. Epub 2017 Jul 21.

PMID:
28733895
8.

Commensal bacteria at the crossroad between cholesterol homeostasis and chronic inflammation in atherosclerosis.

Kasahara K, Tanoue T, Yamashita T, Yodoi K, Matsumoto T, Emoto T, Mizoguchi T, Hayashi T, Kitano N, Sasaki N, Atarashi K, Honda K, Hirata KI.

J Lipid Res. 2017 Mar;58(3):519-528. doi: 10.1194/jlr.M072165. Epub 2017 Jan 27.

9.

Corrigendum: A subpopulation of high IL-21-producing CD4+ T cells in Peyer's Patches is induced by the microbiota and regulates germinal centers.

Jones L, Ho WQ, Ying S, Ramakrishna L, Srinivasan KG, Yurieva M, Ng WP, Subramaniam S, Hamadee NH, Joseph S, Dolpady J, Atarashi K, Honda K, Zolezzi F, Poidinger M, Lafaille JJ, Curotto de Lafaille MA.

Sci Rep. 2016 Oct 10;6:34899. doi: 10.1038/srep34899. No abstract available.

10.

A subpopulation of high IL-21-producing CD4(+) T cells in Peyer's Patches is induced by the microbiota and regulates germinal centers.

Jones L, Ho WQ, Ying S, Ramakrishna L, Srinivasan KG, Yurieva M, Ng WP, Subramaniam S, Hamadee NH, Joseph S, Dolpady J, Atarashi K, Honda K, Zolezzi F, Poidinger M, Lafaille JJ, Curotto de Lafaille MA.

Sci Rep. 2016 Aug 8;6:30784. doi: 10.1038/srep30784. Erratum in: Sci Rep. 2016 Oct 10;6:34899.

11.

Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.

Ochi T, Feng Y, Kitamoto S, Nagao-Kitamoto H, Kuffa P, Atarashi K, Honda K, Teitelbaum DH, Kamada N.

Sci Rep. 2016 Jun 15;6:27634. doi: 10.1038/srep27634.

12.

Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers.

Saito T, Nishikawa H, Wada H, Nagano Y, Sugiyama D, Atarashi K, Maeda Y, Hamaguchi M, Ohkura N, Sato E, Nagase H, Nishimura J, Yamamoto H, Takiguchi S, Tanoue T, Suda W, Morita H, Hattori M, Honda K, Mori M, Doki Y, Sakaguchi S.

Nat Med. 2016 Jun;22(6):679-84. doi: 10.1038/nm.4086. Epub 2016 Apr 25.

PMID:
27111280
13.

Development and maintenance of intestinal regulatory T cells.

Tanoue T, Atarashi K, Honda K.

Nat Rev Immunol. 2016 May;16(5):295-309. doi: 10.1038/nri.2016.36. Epub 2016 Apr 18. Review.

PMID:
27087661
14.

Requirement of full TCR repertoire for regulatory T cells to maintain intestinal homeostasis.

Nishio J, Baba M, Atarashi K, Tanoue T, Negishi H, Yanai H, Habu S, Hori S, Honda K, Taniguchi T.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):12770-5. doi: 10.1073/pnas.1516617112. Epub 2015 Sep 29.

15.

Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells.

Atarashi K, Tanoue T, Ando M, Kamada N, Nagano Y, Narushima S, Suda W, Imaoka A, Setoyama H, Nagamori T, Ishikawa E, Shima T, Hara T, Kado S, Jinnohara T, Ohno H, Kondo T, Toyooka K, Watanabe E, Yokoyama S, Tokoro S, Mori H, Noguchi Y, Morita H, Ivanov II, Sugiyama T, Nuñez G, Camp JG, Hattori M, Umesaki Y, Honda K.

Cell. 2015 Oct 8;163(2):367-80. doi: 10.1016/j.cell.2015.08.058. Epub 2015 Sep 24.

16.

MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cells.

Ohnmacht C, Park JH, Cording S, Wing JB, Atarashi K, Obata Y, Gaboriau-Routhiau V, Marques R, Dulauroy S, Fedoseeva M, Busslinger M, Cerf-Bensussan N, Boneca IG, Voehringer D, Hase K, Honda K, Sakaguchi S, Eberl G.

Science. 2015 Aug 28;349(6251):989-93. doi: 10.1126/science.aac4263. Epub 2015 Jul 9.

17.

Foxp3(+) T cells regulate immunoglobulin a selection and facilitate diversification of bacterial species responsible for immune homeostasis.

Kawamoto S, Maruya M, Kato LM, Suda W, Atarashi K, Doi Y, Tsutsui Y, Qin H, Honda K, Okada T, Hattori M, Fagarasan S.

Immunity. 2014 Jul 17;41(1):152-65. doi: 10.1016/j.immuni.2014.05.016. Epub 2014 Jul 10.

18.

The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells.

Obata Y, Furusawa Y, Endo TA, Sharif J, Takahashi D, Atarashi K, Nakayama M, Onawa S, Fujimura Y, Takahashi M, Ikawa T, Otsubo T, Kawamura YI, Dohi T, Tajima S, Masumoto H, Ohara O, Honda K, Hori S, Ohno H, Koseki H, Hase K.

Nat Immunol. 2014 Jun;15(6):571-9. doi: 10.1038/ni.2886. Epub 2014 Apr 28.

PMID:
24777532
19.

Characterization of the 17 strains of regulatory T cell-inducing human-derived Clostridia.

Narushima S, Sugiura Y, Oshima K, Atarashi K, Hattori M, Suematsu M, Honda K.

Gut Microbes. 2014 May-Jun;5(3):333-9. doi: 10.4161/gmic.28572. Epub 2014 Mar 18.

20.

Simultaneous mobile thrombi of the aortic valve and thoracic aorta.

Mihara W, Matsushita A, Atarashi K, Aoki N.

Eur J Cardiothorac Surg. 2014 Nov;46(5):923. doi: 10.1093/ejcts/ezu063. Epub 2014 Feb 26. No abstract available.

PMID:
24578410
21.

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells.

Furusawa Y, Obata Y, Fukuda S, Endo TA, Nakato G, Takahashi D, Nakanishi Y, Uetake C, Kato K, Kato T, Takahashi M, Fukuda NN, Murakami S, Miyauchi E, Hino S, Atarashi K, Onawa S, Fujimura Y, Lockett T, Clarke JM, Topping DL, Tomita M, Hori S, Ohara O, Morita T, Koseki H, Kikuchi J, Honda K, Hase K, Ohno H.

Nature. 2013 Dec 19;504(7480):446-50. doi: 10.1038/nature12721. Epub 2013 Nov 13. Erratum in: Nature. 2014 Feb 13;506(7487):254.

PMID:
24226770
22.

MAVS-dependent IRF3/7 bypass of interferon β-induction restricts the response to measles infection in CD150Tg mouse bone marrow-derived dendritic cells.

Takaki H, Honda K, Atarashi K, Kobayashi F, Ebihara T, Oshiumi H, Matsumoto M, Shingai M, Seya T.

Mol Immunol. 2014 Feb;57(2):100-10. doi: 10.1016/j.molimm.2013.08.007. Epub 2013 Oct 4.

23.

Monocyte-derived dendritic cells perform hemophagocytosis to fine-tune excessive immune responses.

Ohyagi H, Onai N, Sato T, Yotsumoto S, Liu J, Akiba H, Yagita H, Atarashi K, Honda K, Roers A, Müller W, Kurabayashi K, Hosoi-Amaike M, Takahashi N, Hirokawa M, Matsushima K, Sawada K, Ohteki T.

Immunity. 2013 Sep 19;39(3):584-98. doi: 10.1016/j.immuni.2013.06.019. Epub 2013 Sep 12.

24.

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota.

Atarashi K, Tanoue T, Oshima K, Suda W, Nagano Y, Nishikawa H, Fukuda S, Saito T, Narushima S, Hase K, Kim S, Fritz JV, Wilmes P, Ueha S, Matsushima K, Ohno H, Olle B, Sakaguchi S, Taniguchi T, Morita H, Hattori M, Honda K.

Nature. 2013 Aug 8;500(7461):232-6. doi: 10.1038/nature12331. Epub 2013 Jul 10.

PMID:
23842501
25.

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome.

Yoshimoto S, Loo TM, Atarashi K, Kanda H, Sato S, Oyadomari S, Iwakura Y, Oshima K, Morita H, Hattori M, Honda K, Ishikawa Y, Hara E, Ohtani N.

Nature. 2013 Jul 4;499(7456):97-101. doi: 10.1038/nature12347. Epub 2013 Jun 26. Erratum in: Nature. 2014 Feb 20;506(7488):396. Hattori, Masahisa [corrected to Hattori, Masahira].

PMID:
23803760
26.

IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses.

Schlitzer A, McGovern N, Teo P, Zelante T, Atarashi K, Low D, Ho AW, See P, Shin A, Wasan PS, Hoeffel G, Malleret B, Heiseke A, Chew S, Jardine L, Purvis HA, Hilkens CM, Tam J, Poidinger M, Stanley ER, Krug AB, Renia L, Sivasankar B, Ng LG, Collin M, Ricciardi-Castagnoli P, Honda K, Haniffa M, Ginhoux F.

Immunity. 2013 May 23;38(5):970-83. doi: 10.1016/j.immuni.2013.04.011.

27.

[Changes in infection management brought about by societal events. Discussion].

Ohmagari N, Sakurai S, Taniguchi K, Fujikura Y, Atarashi K.

Nihon Naika Gakkai Zasshi. 2012 Nov 10;101(11):3201-17. Japanese. No abstract available.

PMID:
23520662
28.

[Discussion meeting on the effect of social event over the practice of infectious diseases].

Ohmagari N, Sakurai S, Taniguchi K, Fujikura Y, Atarashi K.

Nihon Naika Gakkai Zasshi. 2012 Nov 10;101(11):3201-17. Japanese. No abstract available.

PMID:
23342594
29.

Transcriptional reprogramming of mature CD4⁺ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes.

Mucida D, Husain MM, Muroi S, van Wijk F, Shinnakasu R, Naoe Y, Reis BS, Huang Y, Lambolez F, Docherty M, Attinger A, Shui JW, Kim G, Lena CJ, Sakaguchi S, Miyamoto C, Wang P, Atarashi K, Park Y, Nakayama T, Honda K, Ellmeier W, Kronenberg M, Taniuchi I, Cheroutre H.

Nat Immunol. 2013 Mar;14(3):281-9. doi: 10.1038/ni.2523. Epub 2013 Jan 20.

30.

Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine.

Kusu T, Kayama H, Kinoshita M, Jeon SG, Ueda Y, Goto Y, Okumura R, Saiga H, Kurakawa T, Ikeda K, Maeda Y, Nishimura J, Arima Y, Atarashi K, Honda K, Murakami M, Kunisawa J, Kiyono H, Okumura M, Yamamoto M, Takeda K.

J Immunol. 2013 Jan 15;190(2):774-83. doi: 10.4049/jimmunol.1103067. Epub 2012 Dec 14.

31.

Addition of UVA-absorber butyl methoxy dibenzoylmethane to topical ketoprofen formulation reduces ketoprofen-photoallergic reaction.

Atarashi K, Takano M, Kato S, Kuma H, Nakanishi M, Tokura Y.

J Photochem Photobiol B. 2012 Aug 1;113:56-62. doi: 10.1016/j.jphotobiol.2012.05.002. Epub 2012 May 17.

PMID:
22652332
32.

Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses.

Negishi H, Yanai H, Nakajima A, Koshiba R, Atarashi K, Matsuda A, Matsuki K, Miki S, Doi T, Aderem A, Nishio J, Smale ST, Honda K, Taniguchi T.

Nat Immunol. 2012 May 20;13(7):659-66. doi: 10.1038/ni.2307.

PMID:
22610141
33.

Microbiota in autoimmunity and tolerance.

Atarashi K, Honda K.

Curr Opin Immunol. 2011 Dec;23(6):761-8. doi: 10.1016/j.coi.2011.11.002. Epub 2011 Nov 22. Review.

PMID:
22115876
34.

Regulation of Th17 cell differentiation by intestinal commensal bacteria.

Atarashi K, Tanoue T, Umesaki Y, Honda K.

Benef Microbes. 2010 Nov;1(4):327-34. doi: 10.3920/BM2010.0026. Review.

PMID:
21831771
35.

Muscle weakness in extremities and diffuse centrilobular nodules in lungs. HTLV-1-associated bronchiolo-alveolar disorder.

Fujii M, Sumi Y, Atarashi K, Takemura T, Inase N.

Thorax. 2011 Jun;66(6):546-7, 552. doi: 10.1136/thx.2010.156919. Epub 2011 Apr 17. No abstract available.

PMID:
21606478
36.

The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells.

Motomura Y, Kitamura H, Hijikata A, Matsunaga Y, Matsumoto K, Inoue H, Atarashi K, Hori S, Watarai H, Zhu J, Taniguchi M, Kubo M.

Nat Immunol. 2011 May;12(5):450-9. doi: 10.1038/ni.2020. Epub 2011 Apr 3.

37.

[Rapid progressive HTLV-1-associated myelopathy with bronchoalveolar lesions and a long spinal cord lesion extending to almost the entire spinal cord].

Itami R, Sanjo N, Kuwahara H, Yamamoto M, Atarashi K, Yokota T, Mizusawa H.

Rinsho Shinkeigaku. 2011 Feb;51(2):130-4. Japanese.

PMID:
21404614
38.

Microbiotal influence on T cell subset development.

Atarashi K, Umesaki Y, Honda K.

Semin Immunol. 2011 Apr;23(2):146-53. doi: 10.1016/j.smim.2011.01.010. Epub 2011 Feb 3. Review.

PMID:
21292500
39.

Induction of colonic regulatory T cells by indigenous Clostridium species.

Atarashi K, Tanoue T, Shima T, Imaoka A, Kuwahara T, Momose Y, Cheng G, Yamasaki S, Saito T, Ohba Y, Taniguchi T, Takeda K, Hori S, Ivanov II, Umesaki Y, Itoh K, Honda K.

Science. 2011 Jan 21;331(6015):337-41. doi: 10.1126/science.1198469. Epub 2010 Dec 23.

40.

Inhibitory mechanisms of the transcriptional activity of androgen receptor by resveratrol: Implication of DNA binding and acetylation of the receptor.

Harada N, Atarashi K, Murata Y, Yamaji R, Nakano Y, Inui H.

J Steroid Biochem Mol Biol. 2011 Jan;123(1-2):65-70. doi: 10.1016/j.jsbmb.2010.11.002. Epub 2010 Nov 10.

PMID:
21073951
41.

Induction of lamina propria Th17 cells by intestinal commensal bacteria.

Atarashi K, Tanoue T, Honda K.

Vaccine. 2010 Nov 23;28(50):8036-8. doi: 10.1016/j.vaccine.2010.09.026. Epub 2010 Sep 17.

PMID:
20849872
42.

A novel in vivo inducible dendritic cell ablation model in mice.

Okuyama M, Kayama H, Atarashi K, Saiga H, Kimura T, Waisman A, Yamamoto M, Takeda K.

Biochem Biophys Res Commun. 2010 Jul 2;397(3):559-63.

PMID:
20617552
43.

Induction of intestinal Th17 cells by segmented filamentous bacteria.

Ivanov II, Atarashi K, Manel N, Brodie EL, Shima T, Karaoz U, Wei D, Goldfarb KC, Santee CA, Lynch SV, Tanoue T, Imaoka A, Itoh K, Takeda K, Umesaki Y, Honda K, Littman DR.

Cell. 2009 Oct 30;139(3):485-98. doi: 10.1016/j.cell.2009.09.033.

44.

NFATc1 mediates Toll-like receptor-independent innate immune responses during Trypanosoma cruzi infection.

Kayama H, Koga R, Atarashi K, Okuyama M, Kimura T, Mak TW, Uematsu S, Akira S, Takayanagi H, Honda K, Yamamoto M, Takeda K.

PLoS Pathog. 2009 Jul;5(7):e1000514. doi: 10.1371/journal.ppat.1000514. Epub 2009 Jul 17.

45.

Fra-1 negatively regulates lipopolysaccharide-mediated inflammatory responses.

Morishita H, Saito F, Kayama H, Atarashi K, Kuwata H, Yamamoto M, Takeda K.

Int Immunol. 2009 Apr;21(4):457-65. doi: 10.1093/intimm/dxp015. Epub 2009 Feb 27.

PMID:
19251936
46.

Skin application of ketoprofen systemically suppresses contact hypersensitivity by inducing CD4(+) CD25(+) regulatory T cells.

Atarashi K, Mori T, Yoshiki R, Kabashima K, Kuma H, Tokura Y.

J Dermatol Sci. 2009 Mar;53(3):216-21. doi: 10.1016/j.jdermsci.2008.10.011. Epub 2009 Jan 20.

PMID:
19157794
47.

IL-10-producing Langerhans cells and regulatory T cells are responsible for depressed contact hypersensitivity in grafted skin.

Yoshiki R, Kabashima K, Sugita K, Atarashi K, Shimauchi T, Tokura Y.

J Invest Dermatol. 2009 Mar;129(3):705-13. doi: 10.1038/jid.2008.304. Epub 2008 Oct 9.

48.

ATP drives lamina propria T(H)17 cell differentiation.

Atarashi K, Nishimura J, Shima T, Umesaki Y, Yamamoto M, Onoue M, Yagita H, Ishii N, Evans R, Honda K, Takeda K.

Nature. 2008 Oct 9;455(7214):808-12. doi: 10.1038/nature07240. Epub 2008 Aug 20.

PMID:
18716618
49.

Evaluation of photoallergic potential of chemicals using THP-1 cells.

Hino R, Orimo H, Kabashima K, Atarashi K, Nakanishi M, Kuma H, Tokura Y.

J Dermatol Sci. 2008 Nov;52(2):140-3. doi: 10.1016/j.jdermsci.2008.06.002. Epub 2008 Aug 6. No abstract available.

PMID:
18693085
50.

Skin application of the nonsteroidal anti-inflammatory drug ketoprofen downmodulates the antigen-presenting ability of Langerhans cells in mice.

Atarashi K, Kabashima K, Akiyama K, Tokura Y.

Br J Dermatol. 2008 Aug;159(2):306-13. doi: 10.1111/j.1365-2133.2008.08683.x. Epub 2008 Jun 28.

PMID:
18565185

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