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Items: 27


Loss of Integrin αvβ8 in Murine Hepatocytes Accelerates Liver Regeneration.

Greenhalgh SN, Matchett KP, Taylor RS, Huang K, Li JT, Saeteurn K, Donnelly MC, Simpson EEM, Pollack JL, Atakilit A, Simpson KJ, Maher JJ, Iredale JP, Sheppard D, Henderson NC.

Am J Pathol. 2019 Feb;189(2):258-271. doi: 10.1016/j.ajpath.2018.10.007. Epub 2018 Nov 16.


Pharmacologic Blockade of αvβ1 Integrin Ameliorates Renal Failure and Fibrosis In Vivo.

Chang Y, Lau WL, Jo H, Tsujino K, Gewin L, Reed NI, Atakilit A, Nunes ACF, DeGrado WF, Sheppard D.

J Am Soc Nephrol. 2017 Jul;28(7):1998-2005. doi: 10.1681/ASN.2015050585. Epub 2017 Feb 20.


Targeting integrin α5β1 ameliorates severe airway hyperresponsiveness in experimental asthma.

Sundaram A, Chen C, Khalifeh-Soltani A, Atakilit A, Ren X, Qiu W, Jo H, DeGrado W, Huang X, Sheppard D.

J Clin Invest. 2017 Jan 3;127(1):365-374. doi: 10.1172/JCI88555. Epub 2016 Dec 5.


Transforming growth factor-β plays divergent roles in modulating vascular remodeling, inflammation, and pulmonary fibrosis in a murine model of scleroderma.

Tsujino K, Reed NI, Atakilit A, Ren X, Sheppard D.

Am J Physiol Lung Cell Mol Physiol. 2017 Jan 1;312(1):L22-L31. doi: 10.1152/ajplung.00428.2016. Epub 2016 Nov 18.


Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8.

Fenton TM, Kelly A, Shuttleworth EE, Smedley C, Atakilit A, Powrie F, Campbell S, Nishimura SL, Sheppard D, Levison S, Worthington JJ, Lehtinen MJ, Travis MA.

Mucosal Immunol. 2017 May;10(3):624-634. doi: 10.1038/mi.2016.94. Epub 2016 Oct 26.


IgA production requires B cell interaction with subepithelial dendritic cells in Peyer's patches.

Reboldi A, Arnon TI, Rodda LB, Atakilit A, Sheppard D, Cyster JG.

Science. 2016 May 13;352(6287):aaf4822. doi: 10.1126/science.aaf4822.


Differential spheroid formation by oral cancer cells.

Lee C, Lee C, Atakilit A, Siu A, Ramos DM.

Anticancer Res. 2014 Dec;34(12):6945-9.


Effective treatment of mouse sepsis with an inhibitory antibody targeting integrin αvβ5.

Su G, Atakilit A, Li JT, Wu N, Luong J, Chen R, Bhattacharya M, Sheppard D.

Crit Care Med. 2013 Feb;41(2):546-53. doi: 10.1097/CCM.0b013e3182711b1e.


Integrin α9β1 in airway smooth muscle suppresses exaggerated airway narrowing.

Chen C, Kudo M, Rutaganira F, Takano H, Lee C, Atakilit A, Robinett KS, Uede T, Wolters PJ, Shokat KM, Huang X, Sheppard D.

J Clin Invest. 2012 Aug;122(8):2916-27. doi: 10.1172/JCI60387. Epub 2012 Jul 9.


IQGAP1 is necessary for pulmonary vascular barrier protection in murine acute lung injury and pneumonia.

Bhattacharya M, Su G, Su X, Oses-Prieto JA, Li JT, Huang X, Hernandez H, Atakilit A, Burlingame AL, Matthay MA, Sheppard D.

Am J Physiol Lung Cell Mol Physiol. 2012 Jul 1;303(1):L12-9. doi: 10.1152/ajplung.00375.2011. Epub 2012 May 4.


Absence of integrin αvβ3 enhances vascular leak in mice by inhibiting endothelial cortical actin formation.

Su G, Atakilit A, Li JT, Wu N, Bhattacharya M, Zhu J, Shieh JE, Li E, Chen R, Sun S, Su CP, Sheppard D.

Am J Respir Crit Care Med. 2012 Jan 1;185(1):58-66. doi: 10.1164/rccm.201108-1381OC.


Short form of α9 promotes α9β1 integrin-dependent cell adhesion by modulating the function of the full-length α9 subunit.

Kon S, Atakilit A, Sheppard D.

Exp Cell Res. 2011 Jul 15;317(12):1774-84. doi: 10.1016/j.yexcr.2011.04.005. Epub 2011 Apr 16.


Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein.

Seibold MA, Reese TA, Choudhry S, Salam MT, Beckman K, Eng C, Atakilit A, Meade K, Lenoir M, Watson HG, Thyne S, Kumar R, Weiss KB, Grammer LC, Avila P, Schleimer RP, Fahy JV, Rodriguez-Santana J, Rodriguez-Cintron W, Boot RG, Sheppard D, Gilliland FD, Locksley RM, Burchard EG.

J Biol Chem. 2009 Jul 17;284(29):19650-8. doi: 10.1074/jbc.M109.012443. Epub 2009 May 12.


EMMPRIN modulates migration and deposition of TN-C in oral squamous carcinoma.

Dang D, Atakilit A, Ramos DM.

Anticancer Res. 2008 Jul-Aug;28(4B):2049-54.


Integrin alpha9beta1 directly binds to vascular endothelial growth factor (VEGF)-A and contributes to VEGF-A-induced angiogenesis.

Vlahakis NE, Young BA, Atakilit A, Hawkridge AE, Issaka RB, Boudreau N, Sheppard D.

J Biol Chem. 2007 May 18;282(20):15187-96. Epub 2007 Mar 14.


The Integrin alpha9beta1 contributes to granulopoiesis by enhancing granulocyte colony-stimulating factor receptor signaling.

Chen C, Huang X, Atakilit A, Zhu QS, Corey SJ, Sheppard D.

Immunity. 2006 Dec;25(6):895-906. Epub 2006 Nov 30.


Integrin alphavbeta5 regulates lung vascular permeability and pulmonary endothelial barrier function.

Su G, Hodnett M, Wu N, Atakilit A, Kosinski C, Godzich M, Huang XZ, Kim JK, Frank JA, Matthay MA, Sheppard D, Pittet JF.

Am J Respir Cell Mol Biol. 2007 Mar;36(3):377-86. Epub 2006 Nov 1.


The lymphangiogenic vascular endothelial growth factors VEGF-C and -D are ligands for the integrin alpha9beta1.

Vlahakis NE, Young BA, Atakilit A, Sheppard D.

J Biol Chem. 2005 Feb 11;280(6):4544-52. Epub 2004 Dec 6.


Matrix metalloproteinases and TGFbeta1 modulate oral tumor cell matrix.

Dang D, Yang Y, Li X, Atakilit A, Regezi J, Eisele D, Ellis D, Ramos DM.

Biochem Biophys Res Commun. 2004 Apr 9;316(3):937-42.


Function-blocking integrin alphavbeta6 monoclonal antibodies: distinct ligand-mimetic and nonligand-mimetic classes.

Weinreb PH, Simon KJ, Rayhorn P, Yang WJ, Leone DR, Dolinski BM, Pearse BR, Yokota Y, Kawakatsu H, Atakilit A, Sheppard D, Violette SM.

J Biol Chem. 2004 Apr 23;279(17):17875-87. Epub 2004 Feb 11.


Specific alpha v integrin receptors modulate K1735 murine melanoma cell behavior.

Yang Y, Dang D, Atakilit A, Schmidt B, Regezi J, Li X, Eisele D, Ellis D, Ramos DM.

Biochem Biophys Res Commun. 2003 Sep 5;308(4):814-9.


Alphavbeta6-Fyn signaling promotes oral cancer progression.

Li X, Yang Y, Hu Y, Dang D, Regezi J, Schmidt BL, Atakilit A, Chen B, Ellis D, Ramos DM.

J Biol Chem. 2003 Oct 24;278(43):41646-53. Epub 2003 Aug 12.


Expression of integrin beta 6 enhances invasive behavior in oral squamous cell carcinoma.

Ramos DM, But M, Regezi J, Schmidt BL, Atakilit A, Dang D, Ellis D, Jordan R, Li X.

Matrix Biol. 2002 Apr;21(3):297-307.


Role of the alpha(v)beta6 integrin in human oral squamous cell carcinoma growth in vivo and in vitro.

Xue H, Atakilit A, Zhu W, Li X, Ramos DM, Pytela R.

Biochem Biophys Res Commun. 2001 Nov 2;288(3):610-8.


Role of the cytoplasmic domain of the beta-subunit of integrin alpha(v)beta6 in infection by foot-and-mouth disease virus.

Miller LC, Blakemore W, Sheppard D, Atakilit A, King AM, Jackson T.

J Virol. 2001 May;75(9):4158-64.


Integrin dependence of brain natriuretic peptide gene promoter activation by mechanical strain.

Liang F, Atakilit A, Gardner DG.

J Biol Chem. 2000 Jul 7;275(27):20355-60.

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