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Items: 8


Chronic allergen exposure drives accumulation of long-lived IgE plasma cells in the bone marrow, giving rise to serological memory.

Asrat S, Kaur N, Liu X, Ben LH, Kajimura D, Murphy AJ, Sleeman MA, Limnander A, Orengo JM.

Sci Immunol. 2020 Jan 10;5(43). pii: eaav8402. doi: 10.1126/sciimmunol.aav8402.


Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4Rα antibody, is required to broadly inhibit type 2 inflammation.

Le Floc'h A, Allinne J, Nagashima K, Scott G, Birchard D, Asrat S, Bai Y, Lim WK, Martin J, Huang T, Potocky TB, Kim JH, Rafique A, Papadopoulos NJ, Stahl N, Yancopoulos GD, Murphy AJ, Sleeman MA, Orengo JM.

Allergy. 2019 Dec 14. doi: 10.1111/all.14151. [Epub ahead of print]


Modulation of the host innate immune and inflammatory response by translocated bacterial proteins.

Asrat S, Davis KM, Isberg RR.

Cell Microbiol. 2015 Jun;17(6):785-795. doi: 10.1111/cmi.12445. Epub 2015 May 4. Review.


Bacterial pathogen manipulation of host membrane trafficking.

Asrat S, de Jesús DA, Hempstead AD, Ramabhadran V, Isberg RR.

Annu Rev Cell Dev Biol. 2014;30:79-109. doi: 10.1146/annurev-cellbio-100913-013439. Epub 2014 Aug 6. Review.


The frustrated host response to Legionella pneumophila is bypassed by MyD88-dependent translation of pro-inflammatory cytokines.

Asrat S, Dugan AS, Isberg RR.

PLoS Pathog. 2014 Jul 24;10(7):e1004229. doi: 10.1371/journal.ppat.1004229. eCollection 2014 Jul.


Robust reference intervals for liver function test (LFT) analytes in newborns and infants.

Melkie M, Yigeremu M, Nigussie P, Asrat S, Gebreegziabher T, Teka T, Kinde S.

BMC Res Notes. 2012 Sep 7;5:493. doi: 10.1186/1756-0500-5-493.


Studies of intestinal morphology and cathepsin B expression in a transgenic mouse aiming at intestine-specific expression of Cath B-EGFP.

Arampatzidou M, Mayer K, Iolyeva ME, Asrat SG, Ravichandran M, Günther T, Schüle R, Reinheckel T, Brix K.

Biol Chem. 2011 Nov;392(11):983-93. doi: 10.1515/BC.2011.096. Epub 2011 Aug 28.


Unmasking genes in a type 1 diabetes-resistant mouse strain that enhances pathogenic CD8 T-cell responses.

Driver JP, Chen YG, Zhang W, Asrat S, Serreze DV.

Diabetes. 2011 Apr;60(4):1354-9. doi: 10.2337/db10-0885. Epub 2011 Feb 9.

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