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Perinatal factors associate with vertebral size and shape but not lumbar lordosis in 10-year-old children.

Pavlova AV, Jeffrey JE, Barr RJ, Aspden RM.

J Anat. 2019 Oct;235(4):749-756. doi: 10.1111/joa.13024. Epub 2019 Jun 20.


Raman Microscopy and Bone.

Goodyear SR, Aspden RM.

Methods Mol Biol. 2019;1914:651-659. doi: 10.1007/978-1-4939-8997-3_35.


Mechanical Properties of Bone Ex Vivo.

Goodyear SR, Aspden RM.

Methods Mol Biol. 2019;1914:241-257. doi: 10.1007/978-1-4939-8997-3_12.


Osteoarthritis as an organ disease: from the cradle to the grave.

Aspden RM, Saunders FR.

Eur Cell Mater. 2019 Jan 30;37:74-87. doi: 10.22203/eCM.v037a06. Review.


Age at Onset of Walking in Infancy Is Associated With Hip Shape in Early Old Age.

Ireland A, Saunders FR, Muthuri SG, Pavlova AV, Hardy RJ, Martin KR, Barr RJ, Adams JE, Kuh D, Aspden RM, Gregory JS, Cooper R.

J Bone Miner Res. 2019 Mar;34(3):455-463. doi: 10.1002/jbmr.3627. Epub 2019 Jan 15.


Associations between back pain across adulthood and spine shape in early old age in a British birth cohort.

Muthuri SG, Pavlova AV, Saunders FR, Hardy RJ, Gregory JS, Barr RJ, Martin KR, Adams JE, Kuh D, Aspden RM, Cooper R.

Sci Rep. 2018 Nov 5;8(1):16309. doi: 10.1038/s41598-018-34628-9.


Identification of Novel Loci Associated With Hip Shape: A Meta-Analysis of Genomewide Association Studies.

Baird DA, Evans DS, Kamanu FK, Gregory JS, Saunders FR, Giuraniuc CV, Barr RJ, Aspden RM, Jenkins D, Kiel DP, Orwoll ES, Cummings SR, Lane NE, Mullin BH, Williams FM, Richards JB, Wilson SG, Spector TD, Faber BG, Lawlor DA, Grundberg E, Ohlsson C, Pettersson-Kymmer U, Capellini TD, Richard D, Beck TJ, Evans DM, Paternoster L, Karasik D, Tobias JH.

J Bone Miner Res. 2019 Feb;34(2):241-251. doi: 10.1002/jbmr.3605. Epub 2018 Nov 26.


Variation in lifting kinematics related to individual intrinsic lumbar curvature: an investigation in healthy adults.

Pavlova AV, Meakin JR, Cooper K, Barr RJ, Aspden RM.

BMJ Open Sport Exerc Med. 2018 Jul 15;4(1):e000374. doi: 10.1136/bmjsem-2018-000374. eCollection 2018.


Body mass index and waist circumference in early adulthood are associated with thoracolumbar spine shape at age 60-64: The Medical Research Council National Survey of Health and Development.

Pavlova AV, Muthuri SG, Cooper R, Saunders FR, Gregory JS, Barr RJ, Martin KR, Adams JE, Kuh D, Hardy RJ, Aspden RM.

PLoS One. 2018 Jun 14;13(6):e0197570. doi: 10.1371/journal.pone.0197570. eCollection 2018.


Investigation of the Relationship Between Susceptibility Loci for Hip Osteoarthritis and Dual X-Ray Absorptiometry-Derived Hip Shape in a Population-Based Cohort of Perimenopausal Women.

Baird DA, Paternoster L, Gregory JS, Faber BG, Saunders FR, Giuraniuc CV, Barr RJ, Lawlor DA, Aspden RM, Tobias JH.

Arthritis Rheumatol. 2018 Dec;70(12):1984-1993. doi: 10.1002/art.40584. Epub 2018 Oct 27.


Significant morphological change in osteoarthritic hips identified over 6-12 months using statistical shape modelling.

Barr RJ, Gregory JS, Yoshida K, Alesci S, Aspden RM, Reid DM.

Osteoarthritis Cartilage. 2018 Jun;26(6):783-789. doi: 10.1016/j.joca.2018.04.004. Epub 2018 Apr 16.


Sex Differences in the Associations between L-Arginine Pathway Metabolites, Skeletal Muscle Mass and Function, and their Responses to Resistance Exercise, in Old Age.

Da Boit M, Tommasi S, Elliot D, Zinellu A, Sotgia S, Sibson R, Meakin JR, Aspden RM, Carru C, Mangoni AA, Gray SR.

J Nutr Health Aging. 2018;22(4):534-540. doi: 10.1007/s12603-017-0964-6.


Mechanical properties of cancellous bone from the acetabulum in relation to acetabular shell fixation and compared with the corresponding femoral head.

van Ladesteijn R, Leslie H, Manning WA, Holland JP, Deehan DJ, Pandorf T, Aspden RM.

Med Eng Phys. 2018 Mar;53:75-81. doi: 10.1016/j.medengphy.2018.01.005. Epub 2018 Feb 1.


Markers of oxidative stress, skeletal muscle mass and function, and their responses to resistance exercise training in older adults.

Carru C, Da Boit M, Paliogiannis P, Zinellu A, Sotgia S, Sibson R, Meakin JR, Aspden RM, Mangoni AA, Gray SR.

Exp Gerontol. 2018 Mar;103:101-106. doi: 10.1016/j.exger.2017.12.024. Epub 2018 Jan 9.


DXA-derived hip shape is related to osteoarthritis: findings from in the MrOS cohort.

Faber BG, Baird D, Gregson CL, Gregory JS, Barr RJ, Aspden RM, Lynch J, Nevitt MC, Lane NE, Orwoll E, Tobias JH; Osteoporotic Fractures in Men (MrOS) Study Research Group.

Osteoarthritis Cartilage. 2017 Dec;25(12):2031-2038. doi: 10.1016/j.joca.2017.09.006. Epub 2017 Sep 21.


Associations between body mass index across adult life and hip shapes at age 60 to 64: Evidence from the 1946 British birth cohort.

Muthuri SG, Saunders FR, Hardy RJ, Pavlova AV, Martin KR, Gregory JS, Barr RJ, Adams JE, Kuh D, Aspden RM, Cooper R.

Bone. 2017 Dec;105:115-121. doi: 10.1016/j.bone.2017.08.017. Epub 2017 Aug 24.


Cross-sectional associations between variations in ankle shape by statistical shape modeling, injury history, and race: the Johnston County Osteoarthritis Project.

Nelson AE, Golightly YM, Lateef S, Renner JB, Jordan JM, Aspden RM, Hillstrom H, Gregory JS.

J Foot Ankle Res. 2017 Jul 26;10:34. doi: 10.1186/s13047-017-0216-3. eCollection 2017.


Age-related changes in the effects of strength training on lower leg muscles in healthy individuals measured using MRI.

Psatha M, Wu Z, Gammie F, Ratkevicius A, Wackerhage H, Redpath TW, Gilbert FJ, Meakin JR, Aspden RM.

BMJ Open Sport Exerc Med. 2017 Jul 20;3(1):e000249. doi: 10.1136/bmjsem-2017-000249. eCollection 2017.


Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development.

Pavlova AV, Saunders FR, Muthuri SG, Gregory JS, Barr RJ, Martin KR, Hardy RJ, Cooper R, Adams JE, Kuh D, Aspden RM.

J Anat. 2017 Aug;231(2):248-259. doi: 10.1111/joa.12631. Epub 2017 May 31.


Hip Shape as a Predictor of Osteoarthritis Progression in a Prospective Population Cohort.

Ahedi HG, Aspden RM, Blizzard LC, Saunders FR, Cicuttini FM, Aitken DA, Jones G, Gregory JS.

Arthritis Care Res (Hoboken). 2017 Oct;69(10):1566-1573. doi: 10.1002/acr.23166.


Sex differences in the effect of fish-oil supplementation on the adaptive response to resistance exercise training in older people: a randomized controlled trial.

Da Boit M, Sibson R, Sivasubramaniam S, Meakin JR, Greig CA, Aspden RM, Thies F, Jeromson S, Hamilton DL, Speakman JR, Hambly C, Mangoni AA, Preston T, Gray SR.

Am J Clin Nutr. 2017 Jan;105(1):151-158. doi: 10.3945/ajcn.116.140780. Epub 2016 Nov 16.


Viscoelastic properties of human and bovine articular cartilage: a comparison of frequency-dependent trends.

Temple DK, Cederlund AA, Lawless BM, Aspden RM, Espino DM.

BMC Musculoskelet Disord. 2016 Oct 6;17(1):419.


Mechanical and material properties of cortical and trabecular bone from cannabinoid receptor-1-null (Cnr1(-/-)) mice.

Khalid AB, Goodyear SR, Ross RA, Aspden RM.

Med Eng Phys. 2016 Oct;38(10):1044-54. doi: 10.1016/j.medengphy.2016.06.024. Epub 2016 Jul 9.


Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing.

Nicod J, Davies RW, Cai N, Hassett C, Goodstadt L, Cosgrove C, Yee BK, Lionikaite V, McIntyre RE, Remme CA, Lodder EM, Gregory JS, Hough T, Joynson R, Phelps H, Nell B, Rowe C, Wood J, Walling A, Bopp N, Bhomra A, Hernandez-Pliego P, Callebert J, Aspden RM, Talbot NP, Robbins PA, Harrison M, Fray M, Launay JM, Pinto YM, Blizard DA, Bezzina CR, Adams DJ, Franken P, Weaver T, Wells S, Brown SD, Potter PK, Klenerman P, Lionikas A, Mott R, Flint J.

Nat Genet. 2016 Aug;48(8):912-8. doi: 10.1038/ng.3595. Epub 2016 Jul 4.


Sex differences in the response to resistance exercise training in older people.

Da Boit M, Sibson R, Meakin JR, Aspden RM, Thies F, Mangoni AA, Gray SR.

Physiol Rep. 2016 Jun;4(12). pii: e12834. doi: 10.14814/phy2.12834.


MRI and the distribution of bone marrow fat in hip osteoarthritis.

Gregory JS, Barr RJ, Varela V, Ahearn TS, Gardiner JL, Gilbert FJ, Redpath TW, Hutchison JD, Aspden RM.

J Magn Reson Imaging. 2017 Jan;45(1):42-50. doi: 10.1002/jmri.25318. Epub 2016 Jun 2.


Can radiographs of hip fractures predict subsequent hip fractures? A shape modelling analysis.

Neilly D, Khan SK, Gregory JS, Aspden RM, Hutchison JD, Deehan DJ.

Injury. 2016 Jul;47(7):1543-6. doi: 10.1016/j.injury.2016.04.023. Epub 2016 May 2.


Variations in Hip Shape Are Associated with Radiographic Knee Osteoarthritis: Cross-sectional and Longitudinal Analyses of the Johnston County Osteoarthritis Project.

Nelson AE, Golightly YM, Renner JB, Schwartz TA, Liu F, Lynch JA, Gregory JS, Aspden RM, Lane NE, Jordan JM.

J Rheumatol. 2016 Feb;43(2):405-10. doi: 10.3899/jrheum.150559. Epub 2015 Dec 15.


The effects of graded levels of calorie restriction: I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse.

Mitchell SE, Tang Z, Kerbois C, Delville C, Konstantopedos P, Bruel A, Derous D, Green C, Aspden RM, Goodyear SR, Chen L, Han JJ, Wang Y, Promislow DE, Lusseau D, Douglas A, Speakman JR.

Oncotarget. 2015 Jun 30;6(18):15902-30.


The influence of the strength of bone on the deformation of acetabular shells: a laboratory experiment in cadavers.

Bone MC, Dold P, Flohr M, Preuss R, Joyce TJ, Aspden RM, Holland J, Deehan D.

Bone Joint J. 2015 Apr;97-B(4):473-7. doi: 10.1302/0301-620X.97B4.35017.


Reproducibility and Diagnostic Accuracy of Kellgren-Lawrence Grading for Osteoarthritis Using Radiographs and Dual-Energy X-ray Absorptiometry Images.

Yoshida K, Barr RJ, Galea-Soler S, Aspden RM, Reid DM, Gregory JS.

J Clin Densitom. 2015 Apr-Jun;18(2):239-44. doi: 10.1016/j.jocd.2014.08.003. Epub 2014 Oct 8.


Using active shape modeling based on MRI to study morphologic and pitch-related functional changes affecting vocal structures and the airway.

Miller NA, Gregory JS, Aspden RM, Stollery PJ, Gilbert FJ.

J Voice. 2014 Sep;28(5):554-64. doi: 10.1016/j.jvoice.2013.12.002. Epub 2014 Mar 12.


The lumbar spine has an intrinsic shape specific to each individual that remains a characteristic throughout flexion and extension.

Pavlova AV, Meakin JR, Cooper K, Barr RJ, Aspden RM.

Eur Spine J. 2014 Apr;23 Suppl 1:S26-32. doi: 10.1007/s00586-013-3162-1. Epub 2014 Jan 11.


The mechanical and material properties of elderly human articular cartilage subject to impact and slow loading.

Burgin LV, Edelsten L, Aspden RM.

Med Eng Phys. 2014 Feb;36(2):226-32. doi: 10.1016/j.medengphy.2013.11.002. Epub 2013 Nov 23.


How many different types of femora are there in primary hip osteoarthritis? An active shape modeling study.

Merle C, Waldstein W, Gregory JS, Goodyear SR, Aspden RM, Aldinger PR, Murray DW, Gill HS.

J Orthop Res. 2014 Mar;32(3):413-22. doi: 10.1002/jor.22518. Epub 2013 Nov 19.


Proximal femoral canal shape is more accurately assessed on AP hip radiographs than AP pelvis radiographs in primary hip osteoarthritis.

Merle C, Waldstein W, Gregory JS, Goodyear SR, Aspden RM, Aldinger PR, Murray DW, Gill HS.

Hip Int. 2013 Sep-Oct;23(5):484-91. doi: 10.5301/hipint.5000040. Epub 2013 May 24.


Can we improve the prediction of hip fracture by assessing bone structure using shape and appearance modelling?

Goodyear SR, Barr RJ, McCloskey E, Alesci S, Aspden RM, Reid DM, Gregory JS.

Bone. 2013 Mar;53(1):188-93. doi: 10.1016/j.bone.2012.11.042. Epub 2012 Dec 6.


Endothelial nitric oxide synthase is not essential for nitric oxide production by osteoblasts subjected to fluid shear stress in vitro.

Bakker AD, Huesa C, Hughes A, Aspden RM, van't Hof RJ, Klein-Nulend J, Helfrich MH.

Calcif Tissue Int. 2013 Mar;92(3):228-39. doi: 10.1007/s00223-012-9670-x. Epub 2012 Dec 1.


The accuracy of active shape modelling and end-plate measurements for characterising the shape of the lumbar spine in the sagittal plane.

Ali AH, Cowan AB, Gregory JS, Aspden RM, Meakin JR.

Comput Methods Biomech Biomed Engin. 2012;15(2):167-72. doi: 10.1080/10255842.2010.518962. Epub 2011 May 24.


Predicting OA progression to total hip replacement: can we do better than risk factors alone using active shape modelling as an imaging biomarker?

Barr RJ, Gregory JS, Reid DM, Aspden RM, Yoshida K, Hosie G, Silman AJ, Alesci S, Macfarlane GJ.

Rheumatology (Oxford). 2012 Mar;51(3):562-70. doi: 10.1093/rheumatology/ker382. Epub 2011 Dec 2.


Mechanical properties of bone ex vivo.

Goodyear SR, Aspden RM.

Methods Mol Biol. 2012;816:555-71. doi: 10.1007/978-1-61779-415-5_35.


Raman microscopy of bone.

Goodyear SR, Aspden RM.

Methods Mol Biol. 2012;816:527-34. doi: 10.1007/978-1-61779-415-5_32.


A longitudinal MRI study of muscle atrophy during lower leg immobilization following ankle fracture.

Psatha M, Wu Z, Gammie FM, Ratkevicius A, Wackerhage H, Lee JH, Redpath TW, Gilbert FJ, Ashcroft GP, Meakin JR, Aspden RM.

J Magn Reson Imaging. 2012 Mar;35(3):686-95. doi: 10.1002/jmri.22864. Epub 2011 Nov 1.


Non-immortalized human tenocyte cultures as a vehicle for understanding cellular aspects to tendinopathy.

Yao L, Bestwick CS, Bestwick LA, Aspden RM, Maffulli N.

Transl Med UniSa. 2011 Oct 17;1:173-94. Print 2011 Sep.


A recent paper by Abouhossein et al. (2010) investigates the long-sharing mechanism of loads between the disc, ligaments and facet joints of the human lumbar spine.

Aspden RM.

Comput Methods Biomech Biomed Engin. 2012;15(9):1011-2; author reply 1013-4. doi: 10.1080/10255842.2011.566417. Epub 2011 Jun 27. No abstract available.


Analysis of sequential cytokine release after ACL reconstruction.

Hayward AL, Deehan DJ, Aspden RM, Sutherland AG.

Knee Surg Sports Traumatol Arthrosc. 2011 Oct;19(10):1709-15. doi: 10.1007/s00167-011-1486-0. Epub 2011 Mar 29.


The effects of humming and pitch on craniofacial and craniocervical morphology measured using MRI.

Miller NA, Gregory JS, Semple SI, Aspden RM, Stollery PJ, Gilbert FJ.

J Voice. 2012 Jan;26(1):90-101. doi: 10.1016/j.jvoice.2010.10.017. Epub 2011 Mar 24.


PHOSPHO1 is essential for mechanically competent mineralization and the avoidance of spontaneous fractures.

Huesa C, Yadav MC, Finnilä MA, Goodyear SR, Robins SP, Tanner KE, Aspden RM, Millán JL, Farquharson C.

Bone. 2011 May 1;48(5):1066-74. doi: 10.1016/j.bone.2011.01.010. Epub 2011 Jan 25.


Relationships between vocal structures, the airway, and craniocervical posture investigated using magnetic resonance imaging.

Miller NA, Gregory JS, Semple SI, Aspden RM, Stollery PJ, Gilbert FJ.

J Voice. 2012 Jan;26(1):102-9. doi: 10.1016/j.jvoice.2010.10.016. Epub 2011 Jan 14.


India ink and cartilage.

Aspden RM.

Osteoarthritis Cartilage. 2011 Mar;19(3):332; author reply 333-5. doi: 10.1016/j.joca.2010.10.028. Epub 2011 Jan 5. No abstract available.

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