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Items: 26


Microglia-specific targeting by novel capsid-modified AAV6 vectors.

Rosario AM, Cruz PE, Ceballos-Diaz C, Strickland MR, Siemienski Z, Pardo M, Schob KL, Li A, Aslanidi GV, Srivastava A, Golde TE, Chakrabarty P.

Mol Ther Methods Clin Dev. 2016 Apr 13;3:16026. doi: 10.1038/mtm.2016.26. eCollection 2016.


The Adeno-Associated Virus Genome Packaging Puzzle.

Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A.

J Mol Genet Med. 2015 Aug;9(3). pii: 175. Epub 2015 Jul 15. No abstract available.


Site-Directed Mutagenesis of Surface-Exposed Lysine Residues Leads to Improved Transduction by AAV2, But Not AAV8, Vectors in Murine Hepatocytes In Vivo.

Li B, Ma W, Ling C, Van Vliet K, Huang LY, Agbandje-McKenna M, Srivastava A, Aslanidi GV.

Hum Gene Ther Methods. 2015 Dec;26(6):211-20. doi: 10.1089/hgtb.2015.115. Epub 2015 Oct 27.


Productive life cycle of adeno-associated virus serotype 2 in the complete absence of a conventional polyadenylation signal.

Wang L, Yin Z, Wang Y, Lu Y, Zhang D, Srivastava A, Ling C, Aslanidi GV, Ling C.

J Gen Virol. 2015 Sep;96(9):2780-7. doi: 10.1099/jgv.0.000229. Epub 2015 Jun 30.


Reprogramming Immune Response With Capsid-Optimized AAV6 Vectors for Immunotherapy of Cancer.

Pandya M, Britt K, Hoffman B, Ling C, Aslanidi GV.

J Immunother. 2015 Sep;38(7):292-8. doi: 10.1097/CJI.0000000000000093.


Cytotoxic genes from traditional Chinese medicine inhibit tumor growth both in vitro and in vivo.

Zhang YH, Wang Y, Yusufali AH, Ashby F, Zhang D, Yin ZF, Aslanidi GV, Srivastava A, Ling CQ, Ling C.

J Integr Med. 2014 Nov;12(6):483-94. doi: 10.1016/S2095-4964(14)60057-1.


Enhanced transgene expression from recombinant single-stranded D-sequence-substituted adeno-associated virus vectors in human cell lines in vitro and in murine hepatocytes in vivo.

Ling C, Wang Y, Lu Y, Wang L, Jayandharan GR, Aslanidi GV, Li B, Cheng B, Ma W, Lentz T, Ling C, Xiao X, Samulski RJ, Muzyczka N, Srivastava A.

J Virol. 2015 Jan 15;89(2):952-61. doi: 10.1128/JVI.02581-14. Epub 2014 Oct 29.


Selective in vivo targeting of human liver tumors by optimized AAV3 vectors in a murine xenograft model.

Ling C, Wang Y, Zhang Y, Ejjigani A, Yin Z, Lu Y, Wang L, Wang M, Li J, Hu Z, Aslanidi GV, Zhong L, Gao G, Srivastava A, Ling C.

Hum Gene Ther. 2014 Dec;25(12):1023-34. doi: 10.1089/hum.2014.099.


Pristimerin enhances recombinant adeno-associated virus vector-mediated transgene expression in human cell lines in vitro and murine hepatocytes in vivo.

Wang LN, Wang Y, Lu Y, Yin ZF, Zhang YH, Aslanidi GV, Srivastava A, Ling CQ, Ling C.

J Integr Med. 2014 Jan;12(1):20-34. doi: 10.1016/S2095-4964(14)60003-0.


Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo.

Song L, Kauss MA, Kopin E, Chandra M, Ul-Hasan T, Miller E, Jayandharan GR, Rivers AE, Aslanidi GV, Ling C, Li B, Ma W, Li X, Andino LM, Zhong L, Tarantal AF, Yoder MC, Wong KK Jr, Tan M, Chatterjee S, Srivastava A.

Cytotherapy. 2013 Aug;15(8):986-98. doi: 10.1016/j.jcyt.2013.04.003.


Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors.

Kay CN, Ryals RC, Aslanidi GV, Min SH, Ruan Q, Sun J, Dyka FM, Kasuga D, Ayala AE, Van Vliet K, Agbandje-McKenna M, Hauswirth WW, Boye SL, Boye SE.

PLoS One. 2013 Apr 26;8(4):e62097. doi: 10.1371/journal.pone.0062097. Print 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/99ee1789-a658-4fb0-8593-40a40e9f344a.


Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?

Aslanidi GV, Rivers AE, Ortiz L, Song L, Ling C, Govindasamy L, Van Vliet K, Tan M, Agbandje-McKenna M, Srivastava A.

PLoS One. 2013;8(3):e59142. doi: 10.1371/journal.pone.0059142. Epub 2013 Mar 19.


High-efficiency transduction of primary human hematopoietic stem cells and erythroid lineage-restricted expression by optimized AAV6 serotype vectors in vitro and in a murine xenograft model in vivo.

Song L, Li X, Jayandharan GR, Wang Y, Aslanidi GV, Ling C, Zhong L, Gao G, Yoder MC, Ling C, Tan M, Srivastava A.

PLoS One. 2013;8(3):e58757. doi: 10.1371/journal.pone.0058757. Epub 2013 Mar 14.


Development of Novel Recombinant AAV Vectors and Strategies for the Potential Gene Therapy of Hemophilia.

Zhong L, Jayandharan GR, Aslanidi GV, Zolotukhin S, Herzog RW, Srivastava A.

J Genet Syndr Gene Ther. 2012 Jan 10;S1. pii: 008.


Limitations of encapsidation of recombinant self-complementary adeno-associated viral genomes in different serotype capsids and their quantitation.

Wang Y, Ling C, Song L, Wang L, Aslanidi GV, Tan M, Ling C, Srivastava A.

Hum Gene Ther Methods. 2012 Aug;23(4):225-33. doi: 10.1089/hgtb.2012.090.


High-efficiency transduction of human monocyte-derived dendritic cells by capsid-modified recombinant AAV2 vectors.

Aslanidi GV, Rivers AE, Ortiz L, Govindasamy L, Ling C, Jayandharan GR, Zolotukhin S, Agbandje-McKenna M, Srivastava A.

Vaccine. 2012 Jun 6;30(26):3908-17. doi: 10.1016/j.vaccine.2012.03.079. Epub 2012 Apr 10.


Innate Immune Responses to AAV Vectors.

Rogers GL, Martino AT, Aslanidi GV, Jayandharan GR, Srivastava A, Herzog RW.

Front Microbiol. 2011 Sep 19;2:194. doi: 10.3389/fmicb.2011.00194. eCollection 2011.


Development of optimized AAV3 serotype vectors: mechanism of high-efficiency transduction of human liver cancer cells.

Cheng B, Ling C, Dai Y, Lu Y, Glushakova LG, Gee SW, McGoogan KE, Aslanidi GV, Park M, Stacpoole PW, Siemann D, Liu C, Srivastava A, Ling C.

Gene Ther. 2012 Apr;19(4):375-84. doi: 10.1038/gt.2011.105. Epub 2011 Jul 21.


High-efficiency transduction of liver cancer cells by recombinant adeno-associated virus serotype 3 vectors.

Ling C, Lu Y, Cheng B, McGoogan KE, Gee SW, Ma W, Li B, Aslanidi GV, Srivastava A.

J Vis Exp. 2011 Mar 22;(49). pii: 2538. doi: 10.3791/2538.


High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.

Markusic DM, Herzog RW, Aslanidi GV, Hoffman BE, Li B, Li M, Jayandharan GR, Ling C, Zolotukhin I, Ma W, Zolotukhin S, Srivastava A, Zhong L.

Mol Ther. 2010 Dec;18(12):2048-56. doi: 10.1038/mt.2010.172. Epub 2010 Aug 24.


[Dynamics of bacterial population waves in relation to the function of chemotaxis response].

Aslanidi GV, Dzheliadin TP, Shakhbazian VIu, Tsyganova VG, Tsyganov MA, IvanitskiÄ­ GR.

Biofizika. 2009 Jan-Feb;54(1):41-5. Russian.


Conditions causing wavefront instability in a growing colony of bacterial cells with chemotactic activity.

Aslanidi GV, Aslanidi OV, Tsyganov MA, Holden AV, Ivanitsky GR.

Dokl Biochem Biophys. 2004 Jan-Feb;394:18-20. No abstract available.


Nonstationary dynamics of bacterial population waves.

Tsyganov MA, Aslanidi GV, Shakhbazian V, Biktashev VN, Ivanitsky GR.

Dokl Biochem Biophys. 2001 Sep-Oct;380:364-9. No abstract available.


The mechanism of fractal-like structure formation by bacterial populations.

Tsyganov MA, Kresteva IB, Aslanidi GV, Aslanidi KB, Deev AA, Ivanitsky GR.

J Biol Phys. 1999 Jun;25(2-3):165-76. doi: 10.1023/A:1005153720027.


A possible role of cold-induced ionic stress in cold-induced cell death.

Aslanidi KB, Aslanidi GV, Vachadze DM, Zinchenko VP, Labas YuA, Potapova TV.

Membr Cell Biol. 1997;11(1):57-76. Review.


[Fractal self-organization in Escherichia coli populations: experimental study].

Krest'eva IB, Tsyganov MA, Aslanidi GV, MedvinskiÄ­ AB, IvanitskiÄ­ GR.

Dokl Akad Nauk. 1996 Nov;351(3):406-9. Russian. No abstract available.


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