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Items: 1 to 50 of 77

1.

Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.

Butler VJ, Gao F, Corrales CI, Cortopassi WA, Caballero B, Vohra M, Ashrafi K, Cuervo AM, Jacobson MP, Coppola G, Kao AW.

PLoS Genet. 2019 Aug 9;15(8):e1008295. doi: 10.1371/journal.pgen.1008295. eCollection 2019 Aug.

2.

Health impact and related cost of ambient air pollution in Tehran.

Bayat R, Ashrafi K, Shafiepour Motlagh M, Hassanvand MS, Daroudi R, Fink G, Künzli N.

Environ Res. 2019 Sep;176:108547. doi: 10.1016/j.envres.2019.108547. Epub 2019 Jun 19.

PMID:
31247432
3.

Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport.

Butler VJ, Salazar DA, Soriano-Castell D, Alves-Ferreira M, Dennissen FJA, Vohra M, Oses-Prieto JA, Li KH, Wang AL, Jing B, Li B, Groisman A, Gutierrez E, Mooney S, Burlingame AL, Ashrafi K, Mandelkow EM, Encalada SE, Kao AW.

Hum Mol Genet. 2019 May 1;28(9):1498-1514. doi: 10.1093/hmg/ddy442.

4.

Genetic diversity of an avian nasal schistosome causing cercarial dermatitis in the Black Sea-Mediterranean migratory route.

Ashrafi K, Nouroosta A, Sharifdini M, Mahmoudi MR, Rahmati B, Brant SV.

Parasitol Res. 2018 Dec;117(12):3821-3833. doi: 10.1007/s00436-018-6087-0. Epub 2018 Oct 20.

PMID:
30343420
5.

The mTOR Target S6 Kinase Arrests Development in Caenorhabditis elegans When the Heat-Shock Transcription Factor Is Impaired.

Chisnell P, Parenteau TR, Tank E, Ashrafi K, Kenyon C.

Genetics. 2018 Nov;210(3):999-1009. doi: 10.1534/genetics.118.301533. Epub 2018 Sep 18.

PMID:
30228197
6.

Bench-to-clinic development of imageable drug-eluting embolization beads: finding the balance.

Lewis AL, Willis SL, Dreher MR, Tang Y, Ashrafi K, Wood BJ, Levy EB, Sharma KV, Negussie AH, Mikhail AS.

Future Oncol. 2018 Nov;14(26):2741-2760. doi: 10.2217/fon-2018-0196. Epub 2018 Jun 26. Review.

7.

Risk assessment of occupational exposure to benzene using numerical simulation in a complex geometry of a reforming unit of petroleum refinery.

Bayatian M, Ashrafi K, Azari MR, Jafari MJ, Mehrabi Y.

Environ Sci Pollut Res Int. 2018 Apr;25(12):11364-11375. doi: 10.1007/s11356-018-1318-6. Epub 2018 Feb 7.

PMID:
29417483
8.

Kynurenic acid accumulation underlies learning and memory impairment associated with aging.

Vohra M, Lemieux GA, Lin L, Ashrafi K.

Genes Dev. 2018 Jan 1;32(1):14-19. doi: 10.1101/gad.307918.117. Epub 2018 Jan 31.

9.

Source Apportionment of Total Suspended Particles (TSP) by Positive Matrix Factorization (PMF) and Chemical Mass Balance (CMB) Modeling in Ahvaz, Iran.

Ashrafi K, Fallah R, Hadei M, Yarahmadi M, Shahsavani A.

Arch Environ Contam Toxicol. 2018 Aug;75(2):278-294. doi: 10.1007/s00244-017-0500-z. Epub 2018 Jan 8.

PMID:
29313074
10.

Comparison of microsphere penetration with LC Bead LUMI™ versus other commercial microspheres.

Caine M, Zhang X, Hill M, Guo W, Ashrafi K, Bascal Z, Kilpatrick H, Dunn A, Grey D, Bushby R, Bushby A, Willis SL, Dreher MR, Lewis AL.

J Mech Behav Biomed Mater. 2018 Feb;78:46-55. doi: 10.1016/j.jmbbm.2017.10.034. Epub 2017 Oct 31.

11.

Seroprevalence of Human Fasciolosis in Lorestan Province, Western Iran, in 2015-16.

Heydarian P, Ashrafi K, Mohebali M, Kia EB, Aryaeipour M, Chegeni Sharafi A, Mokhayeri H, Bozorgomid A, Rokni MB.

Iran J Parasitol. 2017 Jul-Sep;12(3):389-397.

12.

The beneficial effects of dietary restriction on learning are distinct from its effects on longevity and mediated by depletion of a neuroinhibitory metabolite.

Vohra M, Lemieux GA, Lin L, Ashrafi K.

PLoS Biol. 2017 Aug 1;15(8):e2002032. doi: 10.1371/journal.pbio.2002032. eCollection 2017 Aug.

13.

Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.

Long T, Rojo-Arreola L, Shi D, El-Sakkary N, Jarnagin K, Rock F, Meewan M, Rascón AA Jr, Lin L, Cunningham KA, Lemieux GA, Podust L, Abagyan R, Ashrafi K, McKerrow JH, Caffrey CR.

PLoS Negl Trop Dis. 2017 Jul 13;11(7):e0005680. doi: 10.1371/journal.pntd.0005680. eCollection 2017 Jul.

14.

Towards Hypoxia-responsive Drug-eluting Embolization Beads.

Ashrafi K, Heaysman CL, Phillips GJ, Lloyd AW, Lewis AL.

Int J Pharm. 2017 May 30;524(1-2):226-237. doi: 10.1016/j.ijpharm.2017.03.084. Epub 2017 Mar 31.

15.

Expression, purification and in vitro refolding of the recombinant truncated Saposin-like protein 2 antigen for development of diagnosis of human fascioliasis.

Mirzadeh A, Valadkhani Z, Yoosefy A, Babaie J, Golkar M, Esmaeili Rastaghi AR, Kazemi-Rad E, Ashrafi K.

Acta Trop. 2017 Jul;171:163-171. doi: 10.1016/j.actatropica.2017.03.002. Epub 2017 Mar 11.

PMID:
28300559
16.

Characterization of a novel intrinsically radiopaque Drug-eluting Bead for image-guided therapy: DC Bead LUMI™.

Ashrafi K, Tang Y, Britton H, Domenge O, Blino D, Bushby AJ, Shuturminska K, den Hartog M, Radaelli A, Negussie AH, Mikhail AS, Woods DL, Krishnasamy V, Levy EB, Wood BJ, Willis SL, Dreher MR, Lewis AL.

J Control Release. 2017 Mar 28;250:36-47. doi: 10.1016/j.jconrel.2017.02.001. Epub 2017 Feb 8.

17.

Prevalence of Strongyloides stercoralis and Other Intestinal Parasites among Institutionalized Mentally Disabled Individuals in Rasht, Northern Iran.

Saeidinia A, Tavakoli I, Naghipour MR, Rahmati B, Ghavami Lahiji H, Salkhori O, Ashrafi K.

Iran J Parasitol. 2016 Oct-Dec;11(4):527-533.

18.

Long-term biocompatibility, imaging appearance and tissue effects associated with delivery of a novel radiopaque embolization bead for image-guided therapy.

Sharma KV, Bascal Z, Kilpatrick H, Ashrafi K, Willis SL, Dreher MR, Lewis AL.

Biomaterials. 2016 Oct;103:293-304. doi: 10.1016/j.biomaterials.2016.06.064. Epub 2016 Jul 5.

19.

Investigating Connections between Metabolism, Longevity, and Behavior in Caenorhabditis elegans.

Lemieux GA, Ashrafi K.

Trends Endocrinol Metab. 2016 Aug;27(8):586-596. doi: 10.1016/j.tem.2016.05.004. Epub 2016 Jun 9. Review.

20.

A Novel Inherently Radiopaque Bead for Transarterial Embolization to Treat Liver Cancer - A Pre-clinical Study.

Duran R, Sharma K, Dreher MR, Ashrafi K, Mirpour S, Lin M, Schernthaner RE, Schlachter TR, Tacher V, Lewis AL, Willis S, den Hartog M, Radaelli A, Negussie AH, Wood BJ, Geschwind JF.

Theranostics. 2016 Jan 1;6(1):28-39. doi: 10.7150/thno.13137. eCollection 2016.

21.

The Status of Human and Animal Fascioliasis in Iran: A Narrative Review Article.

Ashrafi K.

Iran J Parasitol. 2015 Jul-Sep;10(3):306-28. Review.

22.

Conserved Genetic Interactions between Ciliopathy Complexes Cooperatively Support Ciliogenesis and Ciliary Signaling.

Yee LE, Garcia-Gonzalo FR, Bowie RV, Li C, Kennedy JK, Ashrafi K, Blacque OE, Leroux MR, Reiter JF.

PLoS Genet. 2015 Nov 5;11(11):e1005627. doi: 10.1371/journal.pgen.1005627. eCollection 2015 Nov.

23.

Neural Regulatory Pathways of Feeding and Fat in Caenorhabditis elegans.

Lemieux GA, Ashrafi K.

Annu Rev Genet. 2015;49:413-38. doi: 10.1146/annurev-genet-120213-092244. Epub 2015 Oct 14. Review.

PMID:
26473379
24.

Familial Trichostrongylus Infection Misdiagnosed as Acute Fascioliasis.

Ashrafi K, Tahbaz A, Sharifdini M, Mas-Coma S.

Emerg Infect Dis. 2015 Oct;21(10):1869-70. doi: 10.3201/eid2110.141392. No abstract available.

25.

Comparison of Nested Polymerase Chain Reaction and Real-Time Polymerase Chain Reaction with Parasitological Methods for Detection of Strongyloides stercoralis in Human Fecal Samples.

Sharifdini M, Mirhendi H, Ashrafi K, Hosseini M, Mohebali M, Khodadadi H, Kia EB.

Am J Trop Med Hyg. 2015 Dec;93(6):1285-91. doi: 10.4269/ajtmh.15-0309. Epub 2015 Sep 8.

26.

Stressing about misplaced fat is a key to longevity.

Lemieux GA, Ashrafi K.

Elife. 2015 Aug 19;4. doi: 10.7554/eLife.10161.

27.

The Endemicity of Human Fascioliasis in Guilan Province, Northern Iran: the Baseline for Implementation of Control Strategies.

Ashrafi K, Saadat F, O'Neill S, Rahmati B, Amin Tahmasbi H, Pius Dalton J, Nadim A, Asadinezhad M, Rezvani SM.

Iran J Public Health. 2015 Apr;44(4):501-11.

28.

An Analysis of Clinical Characteristics of Strongyloides stercoralis in 70 indigenous patients in Iran.

Sharifdini M, Kia EB, Ashrafi K, Hosseini M, Mirhendi H, Mohebali M, Kamranrashani B.

Iran J Parasitol. 2014 Apr-Jun;9(2):155-62.

29.

Distribution of Fasciola hepatica and F. gigantica in the endemic area of Guilan, Iran: Relationships between zonal overlap and phenotypic traits.

Ashrafi K, Valero MA, Peixoto RV, Artigas P, Panova M, Mas-Coma S.

Infect Genet Evol. 2015 Apr;31:95-109. doi: 10.1016/j.meegid.2015.01.009. Epub 2015 Jan 17.

PMID:
25602718
30.

Kynurenic acid is a nutritional cue that enables behavioral plasticity.

Lemieux GA, Cunningham KA, Lin L, Mayer F, Werb Z, Ashrafi K.

Cell. 2015 Jan 15;160(1-2):119-31. doi: 10.1016/j.cell.2014.12.028.

31.

Fascioliasis: a worldwide parasitic disease of importance in travel medicine.

Ashrafi K, Bargues MD, O'Neill S, Mas-Coma S.

Travel Med Infect Dis. 2014 Nov-Dec;12(6 Pt A):636-49. doi: 10.1016/j.tmaid.2014.09.006. Epub 2014 Sep 28. Review.

PMID:
25287722
32.

Insights and challenges in using C. elegans for investigation of fat metabolism.

Lemieux GA, Ashrafi K.

Crit Rev Biochem Mol Biol. 2015 Jan-Feb;50(1):69-84. doi: 10.3109/10409238.2014.959890. Epub 2014 Sep 17. Review.

PMID:
25228063
33.

Fasciola gigantica transmission in the zoonotic fascioliasis endemic lowlands of Guilan, Iran: experimental assessment.

Ashrafi K, Mas-Coma S.

Vet Parasitol. 2014 Sep 15;205(1-2):96-106. doi: 10.1016/j.vetpar.2014.07.017. Epub 2014 Jul 21.

PMID:
25095734
34.

OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin.

Chen L, Shu Y, Liang X, Chen EC, Yee SW, Zur AA, Li S, Xu L, Keshari KR, Lin MJ, Chien HC, Zhang Y, Morrissey KM, Liu J, Ostrem J, Younger NS, Kurhanewicz J, Shokat KM, Ashrafi K, Giacomini KM.

Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9983-8. doi: 10.1073/pnas.1314939111. Epub 2014 Jun 24.

35.

Loss of a neural AMP-activated kinase mimics the effects of elevated serotonin on fat, movement, and hormonal secretions.

Cunningham KA, Bouagnon AD, Barros AG, Lin L, Malard L, Romano-Silva MA, Ashrafi K.

PLoS Genet. 2014 Jun 12;10(6):e1004394. doi: 10.1371/journal.pgen.1004394. eCollection 2014 Jun.

36.

Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses.

Ward JD, Mullaney B, Schiller BJ, He LD, Petnic SE, Couillault C, Pujol N, Bernal TU, Van Gilst MR, Ashrafi K, Ewbank JJ, Yamamoto KR.

PLoS One. 2014 Mar 20;9(3):e92552. doi: 10.1371/journal.pone.0092552. eCollection 2014.

37.

Dopamine signaling regulates fat content through β-oxidation in Caenorhabditis elegans.

Barros AG, Bridi JC, de Souza BR, de Castro Júnior C, de Lima Torres KC, Malard L, Jorio A, de Miranda DM, Ashrafi K, Romano-Silva MA.

PLoS One. 2014 Jan 22;9(1):e85874. doi: 10.1371/journal.pone.0085874. eCollection 2014.

38.

Dust storm simulation over Iran using HYSPLIT.

Ashrafi K, Shafiepour-Motlagh M, Aslemand A, Ghader S.

J Environ Health Sci Eng. 2014 Jan 7;12(1):9. doi: 10.1186/2052-336X-12-9.

39.

Sumoylated NHR-25/NR5A regulates cell fate during C. elegans vulval development.

Ward JD, Bojanala N, Bernal T, Ashrafi K, Asahina M, Yamamoto KR.

PLoS Genet. 2013;9(12):e1003992. doi: 10.1371/journal.pgen.1003992. Epub 2013 Dec 12.

40.

In silico molecular comparisons of C. elegans and mammalian pharmacology identify distinct targets that regulate feeding.

Lemieux GA, Keiser MJ, Sassano MF, Laggner C, Mayer F, Bainton RJ, Werb Z, Roth BL, Shoichet BK, Ashrafi K.

PLoS Biol. 2013 Nov;11(11):e1001712. doi: 10.1371/journal.pbio.1001712. Epub 2013 Nov 19.

41.

Effects of Caenorhabditis elegans sgk-1 mutations on lifespan, stress resistance, and DAF-16/FoxO regulation.

Chen AT, Guo C, Dumas KJ, Ashrafi K, Hu PJ.

Aging Cell. 2013 Oct;12(5):932-40. doi: 10.1111/acel.12120. Epub 2013 Jul 19.

42.

Environmental air pollution and acute cerebrovascular complications: an ecologic study in tehran, iran.

Nabavi SM, Jafari B, Jalali MS, Nedjat S, Ashrafi K, Salahesh A.

Int J Prev Med. 2012 Oct;3(10):723-9.

43.

AMP-activated kinase links serotonergic signaling to glutamate release for regulation of feeding behavior in C. elegans.

Cunningham KA, Hua Z, Srinivasan S, Liu J, Lee BH, Edwards RH, Ashrafi K.

Cell Metab. 2012 Jul 3;16(1):113-21. doi: 10.1016/j.cmet.2012.05.014.

44.

Development of sensitive detection of cryptosporidium and giardia from surface water in iran.

Mahmoudi M, Ashrafi K, Abedinzadeh H, Tahvildar-Bideruni F, Haghighi A, Bandehpour M, Taghipour Lailabadi N, Kazemi B.

Iran J Parasitol. 2011 Aug;6(3):43-51.

45.

Helicobacter pylori serum antibody titers in patients with cerebral non-cardioembolic ischemic stroke.

Mousavi SA, Ataei B, Karimi I, Ashrafi K.

J Res Med Sci. 2011 Mar;16 Suppl 1:S407-11.

46.

Analyses of C. elegans fat metabolic pathways.

Barros AG, Liu J, Lemieux GA, Mullaney BC, Ashrafi K.

Methods Cell Biol. 2012;107:383-407. doi: 10.1016/B978-0-12-394620-1.00013-8.

PMID:
22226531
47.

Is air pollution a risk factor for stroke?

Nabavi SM, Sadat Jalali M, Nedjat S, Ashrafi K, Salahesh A.

Int J Stroke. 2012 Jan;7(1):100. doi: 10.1111/j.1747-4949.2011.00720.x. No abstract available.

PMID:
22188856
48.

Hyperactive neuroendocrine secretion causes size, feeding, and metabolic defects of C. elegans Bardet-Biedl syndrome mutants.

Lee BH, Liu J, Wong D, Srinivasan S, Ashrafi K.

PLoS Biol. 2011 Dec;9(12):e1001219. doi: 10.1371/journal.pbio.1001219. Epub 2011 Dec 13.

49.

Lymnaea schirazensis, an overlooked snail distorting fascioliasis data: genotype, phenotype, ecology, worldwide spread, susceptibility, applicability.

Bargues MD, Artigas P, Khoubbane M, Flores R, Glöer P, Rojas-García R, Ashrafi K, Falkner G, Mas-Coma S.

PLoS One. 2011;6(9):e24567. doi: 10.1371/journal.pone.0024567. Epub 2011 Sep 29.

50.

A whole-organism screen identifies new regulators of fat storage.

Lemieux GA, Liu J, Mayer N, Bainton RJ, Ashrafi K, Werb Z.

Nat Chem Biol. 2011 Apr;7(4):206-13. doi: 10.1038/nchembio.534. Epub 2011 Mar 13.

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