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Items: 17

1.

Secreted histidyl-tRNA synthetase splice variants elaborate major epitopes for autoantibodies in inflammatory myositis.

Zhou JJ, Wang F, Xu Z, Lo WS, Lau CF, Chiang KP, Nangle LA, Ashlock MA, Mendlein JD, Yang XL, Zhang M, Schimmel P.

J Biol Chem. 2014 Jul 11;289(28):19269-75. doi: 10.1074/jbc.C114.571026. Epub 2014 Jun 4.

2.

Sweat chloride as a biomarker of CFTR activity: proof of concept and ivacaftor clinical trial data.

Accurso FJ, Van Goor F, Zha J, Stone AJ, Dong Q, Ordonez CL, Rowe SM, Clancy JP, Konstan MW, Hoch HE, Heltshe SL, Ramsey BW, Campbell PW, Ashlock MA.

J Cyst Fibros. 2014 Mar;13(2):139-47.

3.

Multicenter intestinal current measurements in rectal biopsies from CF and non-CF subjects to monitor CFTR function.

Clancy JP, Szczesniak RD, Ashlock MA, Ernst SE, Fan L, Hornick DB, Karp PH, Khan U, Lymp J, Ostmann AJ, Rezayat A, Starner TD, Sugandha SP, Sun H, Quinney N, Donaldson SH, Rowe SM, Gabriel SE.

PLoS One. 2013 Sep 10;8(9):e73905. doi: 10.1371/journal.pone.0073905. eCollection 2013.

4.

Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.

Clancy JP, Rowe SM, Accurso FJ, Aitken ML, Amin RS, Ashlock MA, Ballmann M, Boyle MP, Bronsveld I, Campbell PW, De Boeck K, Donaldson SH, Dorkin HL, Dunitz JM, Durie PR, Jain M, Leonard A, McCoy KS, Moss RB, Pilewski JM, Rosenbluth DB, Rubenstein RC, Schechter MS, Botfield M, Ordoñez CL, Spencer-Green GT, Vernillet L, Wisseh S, Yen K, Konstan MW.

Thorax. 2012 Jan;67(1):12-8. doi: 10.1136/thoraxjnl-2011-200393. Epub 2011 Aug 8.

5.

Therapeutics development for cystic fibrosis: a successful model for a multisystem genetic disease.

Ashlock MA, Olson ER.

Annu Rev Med. 2011;62:107-25. doi: 10.1146/annurev-med-061509-131034. Review.

PMID:
21226613
6.

Effect of VX-770 in persons with cystic fibrosis and the G551D-CFTR mutation.

Accurso FJ, Rowe SM, Clancy JP, Boyle MP, Dunitz JM, Durie PR, Sagel SD, Hornick DB, Konstan MW, Donaldson SH, Moss RB, Pilewski JM, Rubenstein RC, Uluer AZ, Aitken ML, Freedman SD, Rose LM, Mayer-Hamblett N, Dong Q, Zha J, Stone AJ, Olson ER, Ordoñez CL, Campbell PW, Ashlock MA, Ramsey BW.

N Engl J Med. 2010 Nov 18;363(21):1991-2003. doi: 10.1056/NEJMoa0909825.

7.

A pipeline of therapies for cystic fibrosis.

Ashlock MA, Beall RJ, Hamblett NM, Konstan MW, Penland CM, Ramsey BW, Van Dalfsen JM, Wetmore DR, Campbell PW 3rd.

Semin Respir Crit Care Med. 2009 Oct;30(5):611-26. doi: 10.1055/s-0029-1238919. Epub 2009 Sep 16.

PMID:
19760548
8.

Positional cloning utilizing genomic DNA microarrays: the Niemann-Pick type C gene as a model system.

Stephan DA, Chen Y, Jiang Y, Malechek L, Gu JZ, Robbins CM, Bittner ML, Morris JA, Carstea E, Meltzer PS, Adler K, Garlick R, Trent JM, Ashlock MA.

Mol Genet Metab. 2000 May;70(1):10-8.

PMID:
10833327
9.
10.

Design of modified oligodeoxyribonucleotide probes to detect telomere repeat sequences in FISH assays.

Hacia JG, Novotny EA, Mayer RA, Woski SA, Ashlock MA, Collins FS.

Nucleic Acids Res. 1999 Oct 15;27(20):4034-9.

11.

Fluorescent chloride indicators to assess the efficacy of CFTR cDNA delivery.

Mansoura MK, Biwersi J, Ashlock MA, Verkman AS.

Hum Gene Ther. 1999 Apr 10;10(6):861-75. Review.

PMID:
10223721
12.

An improved method for routine preparation of intact artificial chromosome DNA (340-1000 kb) for transfection into human cells.

Compton ST, Henning KA, Chen M, Mansoura MK, Ashlock MA.

Nucleic Acids Res. 1999 Apr 1;27(7):1762-5.

13.
14.

Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences.

Henning KA, Novotny EA, Compton ST, Guan XY, Liu PP, Ashlock MA.

Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):592-7.

15.

Humanizing the yeast telomerase template.

Henning KA, Moskowitz N, Ashlock MA, Liu PP.

Proc Natl Acad Sci U S A. 1998 May 12;95(10):5667-71.

16.

Transient gene expression from yeast artificial chromosome DNA in mammalian cells is enhanced by adenovirus.

Chen M, Compton ST, Coviello VF, Green ED, Ashlock MA.

Nucleic Acids Res. 1997 Nov 1;25(21):4416-8.

17.

Replacement of the anterior cruciate ligament using a patellar tendon allograft. An experimental study.

Arnoczky SP, Warren RF, Ashlock MA.

J Bone Joint Surg Am. 1986 Mar;68(3):376-85.

PMID:
3949832

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