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Items: 1 to 50 of 53

1.

Transcriptomic analysis of immune response to bacterial lipopolysaccharide in zebra finch (Taeniopygia guttata).

Scalf CS, Chariker JH, Rouchka EC, Ashley NT.

BMC Genomics. 2019 Aug 14;20(1):647. doi: 10.1186/s12864-019-6016-3.

2.

Alerting Doctors About Patient Life Challenges: A Randomized Control Trial of a Previsit Inventory of Contextual Factors.

Weaver FM, Binns-Calvey A, Gonzalez B, Kostovich C, LaVela S, Stroupe KT, Kelly B, Ashley N, Miskevics S, Gerber B, Burkhart L, Schwartz A, Weiner SJ.

MDM Policy Pract. 2019 May 27;4(1):2381468319852334. doi: 10.1177/2381468319852334. eCollection 2019 Jan-Jun.

3.

Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion.

Hua P, Kronsteiner B, van der Garde M, Ashley N, Hernandez D, Tarunina M, Hook L, Choo Y, Roberts I, Mead A, Watt SM.

Sci Rep. 2019 Mar 28;9(1):5300. doi: 10.1038/s41598-019-41803-z.

4.

Colonic epithelial cell diversity in health and inflammatory bowel disease.

Parikh K, Antanaviciute A, Fawkner-Corbett D, Jagielowicz M, Aulicino A, Lagerholm C, Davis S, Kinchen J, Chen HH, Alham NK, Ashley N, Johnson E, Hublitz P, Bao L, Lukomska J, Andev RS, Björklund E, Kessler BM, Fischer R, Goldin R, Koohy H, Simmons A.

Nature. 2019 Mar;567(7746):49-55. doi: 10.1038/s41586-019-0992-y. Epub 2019 Feb 27.

5.

Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability?

Merryweather-Clarke AT, Cook D, Lara BJ, Hua P, Repapi E, Ashley N, Lim SY, Watt SM.

Stem Cell Res Ther. 2018 Dec 19;9(1):351. doi: 10.1186/s13287-018-1095-7.

6.
7.

Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets.

Aulicino A, Rue-Albrecht KC, Preciado-Llanes L, Napolitani G, Ashley N, Cribbs A, Koth J, Lagerholm BC, Ambrose T, Gordon MA, Sims D, Simmons A.

Nat Commun. 2018 Nov 19;9(1):4883. doi: 10.1038/s41467-018-07329-0.

8.

Single-molecule DNA-mapping and whole-genome sequencing of individual cells.

Marie R, Pedersen JN, Bærlocher L, Koprowska K, Pødenphant M, Sabatel C, Zalkovskij M, Mironov A, Bilenberg B, Ashley N, Flyvbjerg H, Bodmer WF, Kristensen A, Mir KU.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11192-11197. doi: 10.1073/pnas.1804194115. Epub 2018 Oct 15.

9.

Cellular polarity modulates drug resistance in primary colorectal cancers via orientation of the multidrug resistance protein ABCB1.

Ashley N, Ouaret D, Bodmer WF.

J Pathol. 2019 Mar;247(3):293-304. doi: 10.1002/path.5179. Epub 2019 Jan 16.

10.

Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease.

Kinchen J, Chen HH, Parikh K, Antanaviciute A, Jagielowicz M, Fawkner-Corbett D, Ashley N, Cubitt L, Mellado-Gomez E, Attar M, Sharma E, Wills Q, Bowden R, Richter FC, Ahern D, Puri KD, Henault J, Gervais F, Koohy H, Simmons A.

Cell. 2018 Oct 4;175(2):372-386.e17. doi: 10.1016/j.cell.2018.08.067. Epub 2018 Sep 27.

11.

Sequencing of human genomes extracted from single cancer cells isolated in a valveless microfluidic device.

Marie R, Pødenphant M, Koprowska K, Bærlocher L, Vulders RCM, Wilding J, Ashley N, McGowan SJ, van Strijp D, van Hemert F, Olesen T, Agersnap N, Bilenberg B, Sabatel C, Schira J, Kristensen A, Bodmer W, van der Zaag PJ, Mir KU.

Lab Chip. 2018 Jun 26;18(13):1891-1902. doi: 10.1039/c8lc00169c.

PMID:
29873383
12.

Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways.

Villeneuve DL, Landesmann B, Allavena P, Ashley N, Bal-Price A, Corsini E, Halappanavar S, Hussell T, Laskin D, Lawrence T, Nikolic-Paterson D, Pallardy M, Paini A, Pieters R, Roth R, Tschudi-Monnet F.

Toxicol Sci. 2018 Jun 1;163(2):346-352. doi: 10.1093/toxsci/kfy047. Review.

13.
14.

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors.

Booth CAG, Barkas N, Neo WH, Boukarabila H, Soilleux EJ, Giotopoulos G, Farnoud N, Giustacchini A, Ashley N, Carrelha J, Jamieson L, Atkinson D, Bouriez-Jones T, Prinjha RK, Milne TA, Teachey DT, Papaemmanuil E, Huntly BJP, Jacobsen SEW, Mead AJ.

Cancer Cell. 2018 Feb 12;33(2):274-291.e8. doi: 10.1016/j.ccell.2018.01.006.

15.

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

Pasricha SR, Lim PJ, Duarte TL, Casu C, Oosterhuis D, Mleczko-Sanecka K, Suciu M, Da Silva AR, Al-Hourani K, Arezes J, McHugh K, Gooding S, Frost JN, Wray K, Santos A, Porto G, Repapi E, Gray N, Draper SJ, Ashley N, Soilleux E, Olinga P, Muckenthaler MU, Hughes JR, Rivella S, Milne TA, Armitage AE, Drakesmith H.

Nat Commun. 2017 Sep 1;8(1):403. doi: 10.1038/s41467-017-00500-z.

16.

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia.

Giustacchini A, Thongjuea S, Barkas N, Woll PS, Povinelli BJ, Booth CAG, Sopp P, Norfo R, Rodriguez-Meira A, Ashley N, Jamieson L, Vyas P, Anderson K, Segerstolpe Å, Qian H, Olsson-Strömberg U, Mustjoki S, Sandberg R, Jacobsen SEW, Mead AJ.

Nat Med. 2017 Jun;23(6):692-702. doi: 10.1038/nm.4336. Epub 2017 May 15.

PMID:
28504724
17.

Introduction to the Special Issue on Neuroendocrine-Immune Interactions: Implications for Integrative and Comparative Physiologists.

Demas GE, Ashley NT.

Horm Behav. 2017 Feb;88:1-3. doi: 10.1016/j.yhbeh.2017.01.005. No abstract available.

PMID:
28189151
18.

Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations.

Liao C, Ashley N, Diot A, Morten K, Phadwal K, Williams A, Fearnley I, Rosser L, Lowndes J, Fratter C, Ferguson DJ, Vay L, Quaghebeur G, Moroni I, Bianchi S, Lamperti C, Downes SM, Sitarz KS, Flannery PJ, Carver J, Dombi E, East D, Laura M, Reilly MM, Mortiboys H, Prevo R, Campanella M, Daniels MJ, Zeviani M, Yu-Wai-Man P, Simon AK, Votruba M, Poulton J.

Neurology. 2017 Jan 10;88(2):131-142. doi: 10.1212/WNL.0000000000003491. Epub 2016 Dec 14.

19.

Neuroendocrine-immune circuits, phenotypes, and interactions.

Ashley NT, Demas GE.

Horm Behav. 2017 Jan;87:25-34. doi: 10.1016/j.yhbeh.2016.10.004. Epub 2016 Oct 17. Review.

20.

Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways.

Psaila B, Barkas N, Iskander D, Roy A, Anderson S, Ashley N, Caputo VS, Lichtenberg J, Loaiza S, Bodine DM, Karadimitris A, Mead AJ, Roberts I.

Genome Biol. 2016 May 3;17:83. doi: 10.1186/s13059-016-0939-7.

21.

Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers.

Hsia LT, Ashley N, Ouaret D, Wang LM, Wilding J, Bodmer WF.

Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):E2162-71. doi: 10.1073/pnas.1603534113. Epub 2016 Mar 28.

22.

Novel environment influences the effect of paradoxical sleep deprivation upon brain and peripheral cytokine gene expression.

Ashley NT, Sams DW, Brown AC, Dumaine JE.

Neurosci Lett. 2016 Feb 26;615:55-9. doi: 10.1016/j.neulet.2016.01.013. Epub 2016 Jan 19.

23.

Separation of cancer cells from white blood cells by pinched flow fractionation.

Pødenphant M, Ashley N, Koprowska K, Mir KU, Zalkovskij M, Bilenberg B, Bodmer W, Kristensen A, Marie R.

Lab Chip. 2015 Dec 21;15(24):4598-606. doi: 10.1039/c5lc01014d. Epub 2015 Oct 29.

PMID:
26510401
24.

Patient-collected audio for performance assessment of the clinical encounter.

Weiner SJ, Schwartz A, Sharma G, Binns-Calvey A, Ashley N, Kelly B, Weaver FM.

Jt Comm J Qual Patient Saf. 2015 Jun;41(6):273-8. No abstract available.

PMID:
25990893
25.

Acute sleep fragmentation induces tissue-specific changes in cytokine gene expression and increases serum corticosterone concentration.

Dumaine JE, Ashley NT.

Am J Physiol Regul Integr Comp Physiol. 2015 Jun 15;308(12):R1062-9. doi: 10.1152/ajpregu.00049.2015. Epub 2015 Apr 15.

26.

Revealing a circadian clock in captive arctic-breeding songbirds, lapland longspurs (Calcarius lapponicus), under constant illumination.

Ashley NT, Ubuka T, Schwabl I, Goymann W, Salli BM, Bentley GE, Buck CL.

J Biol Rhythms. 2014 Dec;29(6):456-69. doi: 10.1177/0748730414552323. Epub 2014 Oct 17.

PMID:
25326246
27.

Exploring the perceived met and unmet need of life-limited children, young people and families.

Coad J, Kaur J, Ashley N, Owens C, Hunt A, Chambers L, Brown E.

J Pediatr Nurs. 2015 Jan-Feb;30(1):45-53. doi: 10.1016/j.pedn.2014.09.007. Epub 2014 Sep 28.

PMID:
25301028
28.

Relationship between genome and epigenome--challenges and requirements for future research.

Almouzni G, Altucci L, Amati B, Ashley N, Baulcombe D, Beaujean N, Bock C, Bongcam-Rudloff E, Bousquet J, Braun S, Bressac-de Paillerets B, Bussemakers M, Clarke L, Conesa A, Estivill X, Fazeli A, Grgurević N, Gut I, Heijmans BT, Hermouet S, Houwing-Duistermaat J, Iacobucci I, Ilaš J, Kandimalla R, Krauss-Etschmann S, Lasko P, Lehmann S, Lindroth A, Majdič G, Marcotte E, Martinelli G, Martinet N, Meyer E, Miceli C, Mills K, Moreno-Villanueva M, Morvan G, Nickel D, Niesler B, Nowacki M, Nowak J, Ossowski S, Pelizzola M, Pochet R, Potočnik U, Radwanska M, Raes J, Rattray M, Robinson MD, Roelen B, Sauer S, Schinzer D, Slagboom E, Spector T, Stunnenberg HG, Tiligada E, Torres-Padilla ME, Tsonaka R, Van Soom A, Vidaković M, Widschwendter M.

BMC Genomics. 2014 Jun 18;15:487. doi: 10.1186/1471-2164-15-487.

29.

Rapidly derived colorectal cancer cultures recapitulate parental cancer characteristics and enable personalized therapeutic assays.

Ashley N, Jones M, Ouaret D, Wilding J, Bodmer WF.

J Pathol. 2014 Sep;234(1):34-45. doi: 10.1002/path.4371. Epub 2014 Jul 7.

PMID:
24797403
30.

Stem cell differentiation and lumen formation in colorectal cancer cell lines and primary tumors.

Ashley N, Yeung TM, Bodmer WF.

Cancer Res. 2013 Sep 15;73(18):5798-809. doi: 10.1158/0008-5472.CAN-13-0454. Epub 2013 Jul 18.

31.

Content coding for contextualization of care: evaluating physician performance at patient-centered decision making.

Weiner SJ, Kelly B, Ashley N, Binns-Calvey A, Sharma G, Schwartz A, Weaver FM.

Med Decis Making. 2014 Jan;34(1):97-106. doi: 10.1177/0272989X13493146. Epub 2013 Jun 19.

PMID:
23784847
32.

Clinical, biochemical, cellular and molecular characterization of mitochondrial DNA depletion syndrome due to novel mutations in the MPV17 gene.

Uusimaa J, Evans J, Smith C, Butterworth A, Craig K, Ashley N, Liao C, Carver J, Diot A, Macleod L, Hargreaves I, Al-Hussaini A, Faqeih E, Asery A, Al Balwi M, Eyaid W, Al-Sunaid A, Kelly D, van Mourik I, Ball S, Jarvis J, Mulay A, Hadzic N, Samyn M, Baker A, Rahman S, Stewart H, Morris AA, Seller A, Fratter C, Taylor RW, Poulton J.

Eur J Hum Genet. 2014 Feb;22(2):184-91. doi: 10.1038/ejhg.2013.112. Epub 2013 May 29.

33.

Patient-centered decision making and health care outcomes: an observational study.

Weiner SJ, Schwartz A, Sharma G, Binns-Calvey A, Ashley N, Kelly B, Dayal A, Patel S, Weaver FM, Harris I.

Ann Intern Med. 2013 Apr 16;158(8):573-9. doi: 10.7326/0003-4819-158-8-201304160-00001.

PMID:
23588745
34.

Sleep deprivation attenuates endotoxin-induced cytokine gene expression independent of day length and circulating cortisol in male Siberian hamsters (Phodopus sungorus).

Ashley NT, Walton JC, Haim A, Zhang N, Prince LA, Fruchey AM, Lieberman RA, Weil ZM, Magalang UJ, Nelson RJ.

J Exp Biol. 2013 Jul 15;216(Pt 14):2581-6. doi: 10.1242/jeb.083832. Epub 2013 Mar 26.

35.

Keeping time under the midnight sun: behavioral and plasma melatonin profiles of free-living Lapland longspurs (Calcarius lapponicus) during the arctic summer.

Ashley NT, Schwabl I, Goymann W, Buck CL.

J Exp Zool A Ecol Genet Physiol. 2013 Jan;319(1):10-22. doi: 10.1002/jez.1768. Epub 2012 Oct 9.

PMID:
23047644
36.

Photoperiod alters duration and intensity of non-rapid eye movement sleep following immune challenge in Siberian hamsters (Phodopus sungorus).

Ashley NT, Zhang N, Weil ZM, Magalang UJ, Nelson RJ.

Chronobiol Int. 2012 Jul;29(6):683-92. doi: 10.3109/07420528.2012.682682.

PMID:
22734569
37.

Regulation of intestinal cancer stem cells.

Ashley N.

Cancer Lett. 2013 Sep 10;338(1):120-6. doi: 10.1016/j.canlet.2012.04.016. Epub 2012 Apr 27. Review.

PMID:
22546285
38.

Glucocorticosteroid concentrations in feces and hair of captive caribou and reindeer following adrenocorticotropic hormone challenge.

Ashley NT, Barboza PS, Macbeth BJ, Janz DM, Cattet MR, Booth RK, Wasser SK.

Gen Comp Endocrinol. 2011 Jul 1;172(3):382-91. doi: 10.1016/j.ygcen.2011.03.029. Epub 2011 Apr 8.

PMID:
21501613
39.

Anticancer DNA intercalators cause p53-dependent mitochondrial DNA nucleoid re-modelling.

Ashley N, Poulton J.

Oncogene. 2009 Nov 5;28(44):3880-91. doi: 10.1038/onc.2009.242. Epub 2009 Aug 17.

40.

Testosterone treatment diminishes sickness behavior in male songbirds.

Ashley NT, Hays QR, Bentley GE, Wingfield JC.

Horm Behav. 2009 Jun;56(1):169-76. doi: 10.1016/j.yhbeh.2009.04.003. Epub 2009 Apr 15.

PMID:
19374904
41.

Mitochondrial DNA is a direct target of anti-cancer anthracycline drugs.

Ashley N, Poulton J.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):450-5. doi: 10.1016/j.bbrc.2008.11.059. Epub 2008 Nov 24.

PMID:
19032935
42.

Depletion of mitochondrial DNA in fibroblast cultures from patients with POLG1 mutations is a consequence of catalytic mutations.

Ashley N, O'Rourke A, Smith C, Adams S, Gowda V, Zeviani M, Brown GK, Fratter C, Poulton J.

Hum Mol Genet. 2008 Aug 15;17(16):2496-506. doi: 10.1093/hmg/ddn150. Epub 2008 May 16. Erratum in: Hum Mol Genet. 2009 Dec 15;18(24):4905-6.

43.

Liver mtDNA content increases during development: a comparison of methods and the importance of age- and tissue-specific controls for the diagnosis of mtDNA depletion.

Morten KJ, Ashley N, Wijburg F, Hadzic N, Parr J, Jayawant S, Adams S, Bindoff L, Bakker HD, Mieli-Vergani G, Zeviani M, Poulton J.

Mitochondrion. 2007 Dec;7(6):386-95. Epub 2007 Sep 21.

PMID:
17981517
44.
45.

Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances.

Ashley N, Adams S, Slama A, Zeviani M, Suomalainen A, Andreu AL, Naviaux RK, Poulton J.

Hum Mol Genet. 2007 Jun 15;16(12):1400-11. Epub 2007 May 3.

PMID:
17483096
46.

Fetal and neonatal exposure to AZT and low-protein diet affects glucose homeostasis: a model with implications for AIDS prevention.

Morten K, Field P, Ashley N, Williams KA, Harris D, Hartley M, Clark A, Poulton J.

Am J Physiol Endocrinol Metab. 2005 Dec;289(6):E1115-8. Epub 2005 Jul 12.

47.

Detection of mitochondrial DNA depletion in living human cells using PicoGreen staining.

Ashley N, Harris D, Poulton J.

Exp Cell Res. 2005 Feb 15;303(2):432-46. Epub 2004 Nov 13.

PMID:
15652355
48.

Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number.

Tyynismaa H, Sembongi H, Bokori-Brown M, Granycome C, Ashley N, Poulton J, Jalanko A, Spelbrink JN, Holt IJ, Suomalainen A.

Hum Mol Genet. 2004 Dec 15;13(24):3219-27. Epub 2004 Oct 27.

PMID:
15509589
49.

Development of an instrument to measure threat related to cardiac events.

Bennett SJ, Puntenney PJ, Walker NL, Ashley ND.

Nurs Res. 1996 Sep-Oct;45(5):266-70.

PMID:
8831652
50.

Prodigiosin 25C: effect in in vitro models for T cell activation and T cell cycling and in vivo for rat heart allografts.

Metcalfe S, Ashley N, Chen Z, Calne RY.

Int Arch Allergy Immunol. 1993;101(2):132-5.

PMID:
7685216

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