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Items: 1 to 50 of 420

1.

Telomere shortening is a hallmark of genetic cardiomyopathies.

Chang ACY, Chang ACH, Kirillova A, Sasagawa K, Su W, Weber G, Lin J, Termglinchan V, Karakikes I, Seeger T, Dainis AM, Hinson JT, Seidman J, Seidman CE, Day JW, Ashley E, Wu JC, Blau HM.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9276-9281. doi: 10.1073/pnas.1714538115. Epub 2018 Aug 27.

2.

Cardiovascular Precision Medicine in the Genomics Era.

Dainis AM, Ashley EA.

JACC Basic Transl Sci. 2018 May 30;3(2):313-326. doi: 10.1016/j.jacbts.2018.01.003. eCollection 2018 Apr. Review.

3.

Time based versus strain based myocardial performance indices in hypertrophic cardiomyopathy, the merging role of left atrial strain.

Kobayashi Y, Moneghetti KJ, Bouajila S, Stolfo D, Finocchiaro G, Kuznetsova T, Liang D, Schnittger I, Ashley E, Wheeler M, Haddad F.

Eur Heart J Cardiovasc Imaging. 2018 Jul 27. doi: 10.1093/ehjci/jey097. [Epub ahead of print]

PMID:
30060097
4.

Genome Sequencing in Hypertrophic Cardiomyopathy.

Ashley EA, Reuter CM, Wheeler MT.

J Am Coll Cardiol. 2018 Jul 24;72(4):430-433. doi: 10.1016/j.jacc.2018.05.029. No abstract available.

PMID:
30025579
5.

Effectiveness and safety of 3 and 5 day courses of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in an area of emerging artemisinin resistance in Myanmar.

Tun KM, Jeeyapant A, Myint AH, Kyaw ZT, Dhorda M, Mukaka M, Cheah PY, Imwong M, Hlaing T, Kyaw TH, Ashley EA, Dondorp A, White NJ, Day NPJ, Smithuis F.

Malar J. 2018 Jul 11;17(1):258. doi: 10.1186/s12936-018-2404-4.

6.

Quantifying primaquine effectiveness and improving adherence: a round table discussion of the APMEN Vivax Working Group.

Thriemer K, Bobogare A, Ley B, Gudo CS, Alam MS, Anstey NM, Ashley E, Baird JK, Gryseels C, Jambert E, Lacerda M, Laihad F, Marfurt J, Pasaribu AP, Poespoprodjo JR, Sutanto I, Taylor WR, van den Boogaard C, Battle KE, Dysoley L, Ghimire P, Hawley B, Hwang J, Khan WA, Mudin RNB, Sumiwi ME, Ahmed R, Aktaruzzaman MM, Awasthi KR, Bardaji A, Bell D, Boaz L, Burdam FH, Chandramohan D, Cheng Q, Chindawongsa K, Culpepper J, Das S, Deray R, Desai M, Domingo G, Duoquan W, Duparc S, Floranita R, Gerth-Guyette E, Howes RE, Hugo C, Jagoe G, Sariwati E, Jhora ST, Jinwei W, Karunajeewa H, Kenangalem E, Lal BK, Landuwulang C, Le Perru E, Lee SE, Makita LS, McCarthy J, Mekuria A, Mishra N, Naket E, Nambanya S, Nausien J, Duc TN, Thi TN, Noviyanti R, Pfeffer D, Qi G, Rahmalia A, Rogerson S, Samad I, Sattabongkot J, Satyagraha A, Shanks D, Sharma SN, Sibley CH, Sungkar A, Syafruddin D, Talukdar A, Tarning J, Ter Kuile F, Thapa S, Theodora M, Huy TT, Waramin E, Waramori G, Woyessa A, Wongsrichanalai C, Xa NX, Yeom JS, Hermawan L, Devine A, Nowak S, Jaya I, Supargiyono S, Grietens KP, Price RN.

Malar J. 2018 Jun 20;17(1):241. doi: 10.1186/s12936-018-2380-8.

7.

Artemether-lumefantrine dosing for malaria treatment in young children and pregnant women: A pharmacokinetic-pharmacodynamic meta-analysis.

Kloprogge F, Workman L, Borrmann S, Tékété M, Lefèvre G, Hamed K, Piola P, Ursing J, Kofoed PE, Mårtensson A, Ngasala B, Björkman A, Ashton M, Friberg Hietala S, Aweeka F, Parikh S, Mwai L, Davis TME, Karunajeewa H, Salman S, Checchi F, Fogg C, Newton PN, Mayxay M, Deloron P, Faucher JF, Nosten F, Ashley EA, McGready R, van Vugt M, Proux S, Price RN, Karbwang J, Ezzet F, Bakshi R, Stepniewska K, White NJ, Guerin PJ, Barnes KI, Tarning J.

PLoS Med. 2018 Jun 12;15(6):e1002579. doi: 10.1371/journal.pmed.1002579. eCollection 2018 Jun.

8.

Mobile Health Advances in Physical Activity, Fitness, and Atrial Fibrillation: Moving Hearts.

McConnell MV, Turakhia MP, Harrington RA, King AC, Ashley EA.

J Am Coll Cardiol. 2018 Jun 12;71(23):2691-2701. doi: 10.1016/j.jacc.2018.04.030. Review.

PMID:
29880130
9.

Artificial Intelligence in Cardiology.

Johnson KW, Torres Soto J, Glicksberg BS, Shameer K, Miotto R, Ali M, Ashley E, Dudley JT.

J Am Coll Cardiol. 2018 Jun 12;71(23):2668-2679. doi: 10.1016/j.jacc.2018.03.521. Review.

10.

Grading antimicrobial susceptibility data quality: room for improvement.

Ashley EA, Dance DAB, Turner P.

Lancet Infect Dis. 2018 Jun;18(6):603-604. doi: 10.1016/S1473-3099(18)30273-1. No abstract available.

PMID:
29856355
11.

Drugs in Development for Malaria.

Ashley EA, Phyo AP.

Drugs. 2018 Jun;78(9):861-879. doi: 10.1007/s40265-018-0911-9.

12.

Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition.

Parikh VN, Liu J, Shang C, Woods C, Chang AC, Zhao M, Charo DN, Grunwald Z, Huang Y, Seo K, Tsao PS, Bernstein D, Ruiz-Lozano P, Quertermous T, Ashley EA.

Am J Physiol Heart Circ Physiol. 2018 Aug 1;315(2):H348-H356. doi: 10.1152/ajpheart.00693.2017. Epub 2018 May 18.

PMID:
29775410
13.

Plasmepsin II-III copy number accounts for bimodal piperaquine resistance among Cambodian Plasmodium falciparum.

Bopp S, Magistrado P, Wong W, Schaffner SF, Mukherjee A, Lim P, Dhorda M, Amaratunga C, Woodrow CJ, Ashley EA, White NJ, Dondorp AM, Fairhurst RM, Ariey F, Menard D, Wirth DF, Volkman SK.

Nat Commun. 2018 May 2;9(1):1769. doi: 10.1038/s41467-018-04104-z.

14.

Acetaminophen or Tylenol? A Retrospective Analysis of Medication Digital Communication Practices.

Ouyang D, Tisdale R, Ashley E, Chi J, Chen JH.

J Gen Intern Med. 2018 Aug;33(8):1218-1220. doi: 10.1007/s11606-018-4455-1. No abstract available.

PMID:
29717410
15.

Biological Insights Into Muscular Strength: Genetic Findings in the UK Biobank.

Tikkanen E, Gustafsson S, Amar D, Shcherbina A, Waggott D, Ashley EA, Ingelsson E.

Sci Rep. 2018 Apr 24;8(1):6451. doi: 10.1038/s41598-018-24735-y.

16.

Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study.

DeBoever C, Tanigawa Y, Lindholm ME, McInnes G, Lavertu A, Ingelsson E, Chang C, Ashley EA, Bustamante CD, Daly MJ, Rivas MA.

Nat Commun. 2018 Apr 24;9(1):1612. doi: 10.1038/s41467-018-03910-9.

17.

A novel field-based molecular assay to detect validated artemisinin-resistant k13 mutants.

Vachot-Ganée L, Khim N, Iannello A, Legrand E, Kim S, Eam R, Khean C, Ken M, Ashley E, Tun KM, Dhorda M, Nosten F, Souleymane IM, Blein S, Pachot A, Ariey F, Kaiser K, Ménard D.

Malar J. 2018 Apr 24;17(1):175. doi: 10.1186/s12936-018-2329-y.

18.

Feasibility and Value of Developing a Regional Antibiogram for Community Hospitals.

Hostler CJ, Moehring RW, Ashley ESD, Johnson M, Davis A, Lewis SS, Sexton DJ, Anderson DJ; CDC Prevention Epicenters Program.

Infect Control Hosp Epidemiol. 2018 Jun;39(6):718-722. doi: 10.1017/ice.2018.71. Epub 2018 Apr 23.

PMID:
29681253
19.

Large Q and S waves in lead III on the electrocardiogram distinguish patients with hypertrophic cardiomyopathy from athletes.

Chen AS, Bent RE, Wheeler M, Knowles JW, Haddad F, Froelicher V, Ashley E, Perez MV.

Heart. 2018 Apr 21. pii: heartjnl-2017-312647. doi: 10.1136/heartjnl-2017-312647. [Epub ahead of print]

PMID:
29680808
20.

Use of primaquine and glucose-6-phosphate dehydrogenase deficiency testing: Divergent policies and practices in malaria endemic countries.

Recht J, Ashley EA, White NJ.

PLoS Negl Trop Dis. 2018 Apr 19;12(4):e0006230. doi: 10.1371/journal.pntd.0006230. eCollection 2018 Apr. Review.

21.

Malaria.

Ashley EA, Pyae Phyo A, Woodrow CJ.

Lancet. 2018 Apr 21;391(10130):1608-1621. doi: 10.1016/S0140-6736(18)30324-6. Epub 2018 Apr 6. Review.

PMID:
29631781
22.

Prevalence and Progression of Late Gadolinium Enhancement in Children and Adolescents with Hypertrophic Cardiomyopathy.

Axelsson Raja A, Farhad H, Valente AM, Couce JP, Jefferies JL, Bundgaard H, Zahka K, Lever H, Murphy AM, Ashley E, Day SM, Sherrid MV, Shi L, Bluemke DA, Canter CE, Colan SD, Ho CY.

Circulation. 2018 Apr 5. pii: CIRCULATIONAHA.117.032966. doi: 10.1161/CIRCULATIONAHA.117.032966. [Epub ahead of print]

PMID:
29622585
23.

Cardiovascular disease: The rise of the genetic risk score.

Knowles JW, Ashley EA.

PLoS Med. 2018 Mar 30;15(3):e1002546. doi: 10.1371/journal.pmed.1002546. eCollection 2018 Mar.

24.

Antimicrobial stewardship and infection prevention-leveraging the synergy: A position paper update.

Manning ML, Septimus EJ, Ashley ESD, Cosgrove SE, Fakih MG, Schweon SJ, Myers FE, Moody JA.

Am J Infect Control. 2018 Apr;46(4):364-368. doi: 10.1016/j.ajic.2018.01.001. No abstract available.

PMID:
29592832
25.

Antimicrobial Stewardship and Infection Prevention-Leveraging the Synergy: A Position Paper Update.

Manning ML, Septimus EJ, Ashley ESD, Cosgrove SE, Fakih MG, Schweon SJ, Myers FE, Moody JA.

Infect Control Hosp Epidemiol. 2018 Apr;39(4):467-472. doi: 10.1017/ice.2018.33. No abstract available.

PMID:
29576043
26.

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects.

Hu R, Morley MP, Brandimarto J, Tucker NR, Parsons VA, Zhao SD, Meder B, Katus HA, Rühle F, Stoll M, Villard E, Cambien F, Lin H, Smith NL, Felix JF, Vasan RS, van der Harst P, Newton-Cheh C, Li J, Kim CE, Hakonarson H, Hannenhalli S, Ashley EA, Moravec CS, Tang WHW, Maillet M, Molkentin JD, Ellinor PT, Margulies KB, Cappola TP.

Circ Genom Precis Med. 2018 Mar;11(3):e001901. doi: 10.1161/CIRCGEN.117.001901.

PMID:
29540468
27.

Applying current normative data to prognosis in heart failure: The Fitness Registry and the Importance of Exercise National Database (FRIEND).

Moneghetti KJ, Hock J, Kaminsky L, Arena R, Lui GK, Haddad F, Wheeler M, Froelicher V, Ashley E, Myers J, Christle JW.

Int J Cardiol. 2018 Jul 15;263:75-79. doi: 10.1016/j.ijcard.2018.02.102. Epub 2018 Feb 27.

PMID:
29525067
28.

A reference equation for maximal aerobic power for treadmill and cycle ergometer exercise testing: Analysis from the FRIEND registry.

de Souza E Silva CG, Kaminsky LA, Arena R, Christle JW, Araújo CGS, Lima RM, Ashley EA, Myers J.

Eur J Prev Cardiol. 2018 May;25(7):742-750. doi: 10.1177/2047487318763958. Epub 2018 Mar 8.

PMID:
29517365
29.

An inventory of supranational antimicrobial resistance surveillance networks involving low- and middle-income countries since 2000.

Ashley EA, Recht J, Chua A, Dance D, Dhorda M, Thomas NV, Ranganathan N, Turner P, Guerin PJ, White NJ, Day NP.

J Antimicrob Chemother. 2018 Mar 5. doi: 10.1093/jac/dky026. [Epub ahead of print]

30.

Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP Synthase, Cause a Metabolic Disorder.

Oláhová M, Yoon WH, Thompson K, Jangam S, Fernandez L, Davidson JM, Kyle JE, Grove ME, Fisk DG, Kohler JN, Holmes M, Dries AM, Huang Y, Zhao C, Contrepois K, Zappala Z, Frésard L, Waggott D, Zink EM, Kim YM, Heyman HM, Stratton KG, Webb-Robertson BM; Undiagnosed Diseases Network, Snyder M, Merker JD, Montgomery SB, Fisher PG, Feichtinger RG, Mayr JA, Hall J, Barbosa IA, Simpson MA, Deshpande C, Waters KM, Koeller DM, Metz TO, Morris AA, Schelley S, Cowan T, Friederich MW, McFarland R, Van Hove JLK, Enns GM, Yamamoto S, Ashley EA, Wangler MF, Taylor RW, Bellen HJ, Bernstein JA, Wheeler MT.

Am J Hum Genet. 2018 Mar 1;102(3):494-504. doi: 10.1016/j.ajhg.2018.01.020. Epub 2018 Feb 22.

31.

Athletic Remodeling in Female College Athletes, the "Morganroth Hypothesis" Revisited.

Kooreman Z, Giraldeau G, Finocchiaro G, Kobayashi Y, Wheeler M, Perez M, Moneghetti K, Oxborough D, George KP, Myers J, Ashley E, Haddad F.

Clin J Sport Med. 2018 Jan 23. doi: 10.1097/JSM.0000000000000501. [Epub ahead of print]

PMID:
29369833
32.

Poor response to artesunate treatment in two patients with severe malaria on the Thai-Myanmar border.

Phyo AP, Win KK, Thu AM, Swe LL, Htike H, Beau C, Sriprawat K, Winterberg M, Proux S, Imwong M, Ashley EA, Nosten F.

Malar J. 2018 Jan 15;17(1):30. doi: 10.1186/s12936-018-2182-z.

33.

A New Approach to Rare Diseases of Children: The Undiagnosed Diseases Network.

Reuter CM, Brimble E, DeFilippo C, Dries AM; Undiagnosed Diseases Network, Enns GM, Ashley EA, Bernstein JA, Fisher PG, Wheeler MT.

J Pediatr. 2018 May;196:291-297.e2. doi: 10.1016/j.jpeds.2017.12.029. Epub 2018 Jan 11. No abstract available.

PMID:
29331327
34.

Right Ventricular Structure and Function in the Veteran Ultramarathon Runner: Is There Evidence for Chronic Maladaptation?

Rothwell O, George K, Somauroo J, Lord R, Stembridge M, Shave R, Hoffman MD, Wilson M, Ashley E, Haddad F, Eijsvogels TMH, Oxborough D.

J Am Soc Echocardiogr. 2018 May;31(5):598-605.e1. doi: 10.1016/j.echo.2017.11.021. Epub 2018 Jan 3.

PMID:
29305036
35.

Impact of Demographic Features, Lifestyle, and Comorbidities on the Clinical Expression of Hypertrophic Cardiomyopathy.

Finocchiaro G, Magavern E, Sinagra G, Ashley E, Papadakis M, Tome-Esteban M, Sharma S, Olivotto I.

J Am Heart Assoc. 2017 Dec 13;6(12). pii: e007161. doi: 10.1161/JAHA.117.007161. Review. No abstract available.

36.

Plasmodium falciparum Kelch 13 mutations and treatment response in patients in Hpa-Pun District, Northern Kayin State, Myanmar.

Bonnington CA, Phyo AP, Ashley EA, Imwong M, Sriprawat K, Parker DM, Proux S, White NJ, Nosten F.

Malar J. 2017 Nov 25;16(1):480. doi: 10.1186/s12936-017-2128-x.

37.

Mind the Gap: Current Challenges and Future State of Heart Failure Care.

McDonald MA, Ashley EA, Fedak PWM, Hawkins N, Januzzi JL, McMurray JJV, Parikh VN, Rao V, Svystonyuk D, Teerlink JR, Virani S.

Can J Cardiol. 2017 Nov;33(11):1434-1449. doi: 10.1016/j.cjca.2017.08.023. Epub 2017 Sep 5. Review.

PMID:
29111107
38.

A non-exercise based V02max prediction using FRIEND dataset with a neural network.

Henriques J, Carvalho P, Rocha T, Paredes S, Cabiddu R, Trimer R, Mendes R, Borghi-Silva A, Kaminsky L, Ashley E, Arena R, Myers J.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:4203-4206. doi: 10.1109/EMBC.2017.8037783.

PMID:
29060824
39.

Human Genome Sequencing at the Population Scale: A Primer on High-Throughput DNA Sequencing and Analysis.

Goldfeder RL, Wall DP, Khoury MJ, Ioannidis JPA, Ashley EA.

Am J Epidemiol. 2017 Oct 15;186(8):1000-1009. doi: 10.1093/aje/kww224. Review.

PMID:
29040395
40.

Care in Specialized Centers and Data Sharing Increase Agreement in Hypertrophic Cardiomyopathy Genetic Test Interpretation.

Furqan A, Arscott P, Girolami F, Cirino AL, Michels M, Day SM, Olivotto I, Ho CY, Ashley E, Green EM, Caleshu C; SHaRe Consortium.

Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001700. doi: 10.1161/CIRCGENETICS.116.001700.

PMID:
28986452
41.

Incremental value of right heart metrics and exercise performance to well-validated risk scores in dilated cardiomyopathy.

Moneghetti KJ, Giraldeau G, Wheeler MT, Kobayashi Y, Vrtovec B, Boulate D, Kuznetsova T, Schnittger I, Wu JC, Myers J, Ashley E, Haddad F.

Eur Heart J Cardiovasc Imaging. 2018 Aug 1;19(8):916-925. doi: 10.1093/ehjci/jex187.

PMID:
28977353
42.

Split dosing of artemisinins does not improve antimalarial therapeutic efficacy.

White NJ, Watson J, Ashley EA.

Sci Rep. 2017 Sep 21;7(1):12132. doi: 10.1038/s41598-017-12483-4.

43.

Load-dependent effects of apelin on murine cardiomyocytes.

Peyronnet R, Bollensdorff C, Capel RA, Rog-Zielinska EA, Woods CE, Charo DN, Lookin O, Fajardo G, Ho M, Quertermous T, Ashley EA, Kohl P.

Prog Biophys Mol Biol. 2017 Nov;130(Pt B):333-343. doi: 10.1016/j.pbiomolbio.2017.09.013. Epub 2017 Sep 18.

44.

A method for determining exercise oscillatory ventilation in heart failure: Prognostic value and practical implications.

Vainshelboim B, Amin A, Christle JW, Hebbal S, Ashley EA, Myers J.

Int J Cardiol. 2017 Dec 15;249:287-291. doi: 10.1016/j.ijcard.2017.09.028. Epub 2017 Sep 14.

PMID:
28918895
45.

Antimicrobial resistance in Africa: a systematic review.

Tadesse BT, Ashley EA, Ongarello S, Havumaki J, Wijegoonewardena M, González IJ, Dittrich S.

BMC Infect Dis. 2017 Sep 11;17(1):616. doi: 10.1186/s12879-017-2713-1.

46.

Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study.

Knowles JW, Zarafshar S, Pavlovic A, Goldstein BA, Tsai S, Li J, McConnell MV, Absher D, Ashley EA, Kiernan M, Ioannidis JPA, Assimes TL.

Front Cardiovasc Med. 2017 Aug 14;4:53. doi: 10.3389/fcvm.2017.00053. eCollection 2017.

47.

Value of Strain Imaging and Maximal Oxygen Consumption in Patients With Hypertrophic Cardiomyopathy.

Moneghetti KJ, Stolfo D, Christle JW, Kobayashi Y, Finocchiaro G, Sinagra G, Myers J, Ashley EA, Haddad F, Wheeler MT.

Am J Cardiol. 2017 Oct 1;120(7):1203-1208. doi: 10.1016/j.amjcard.2017.06.070. Epub 2017 Jul 17.

PMID:
28802509
48.

Navigating Genetic and Phenotypic Uncertainty in Left Ventricular Noncompaction.

Rhee JW, Grove ME, Ashley EA.

Circ Cardiovasc Genet. 2017 Aug;10(4). pii: e001857. doi: 10.1161/CIRCGENETICS.117.001857. No abstract available.

PMID:
28798026
49.

Development of a stereoselective and scalable process for the preparation of a methylcyclobutanol-pyridyl ether.

Kuethe JT, Basu K, Orr RK, Ashley E, Poirier M, Tan L.

Bioorg Med Chem. 2018 Feb 15;26(4):938-944. doi: 10.1016/j.bmc.2017.07.018. Epub 2017 Jul 11.

PMID:
28751197
50.

Contractile reserve and cardiopulmonary exercise parameters in patients with dilated cardiomyopathy, the two dimensions of exercise testing.

Moneghetti KJ, Kobayashi Y, Christle JW, Ariyama M, Vrtovec B, Kouznetsova T, Wilson A, Ashley E, Wheeler MT, Myers J, Haddad F.

Echocardiography. 2017 Aug;34(8):1179-1186. doi: 10.1111/echo.13623. Epub 2017 Jul 6.

PMID:
28681553

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