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Items: 1 to 50 of 67

1.

Pax6 regulation of Sox9 in the retinal pigmented epithelium controls its timely differentiation and choroid vasculature development.

Cohen-Tayar Y, Cohen H, Mitiagin Y, Abarbanel Z, Levy C, Idelson M, Reubinoff B, Itzkovitz S, Raviv S, Kaestner K, Blinder P, Elkon R, Ashery-Padan R.

Development. 2018 Jul 9. pii: dev.163691. doi: 10.1242/dev.163691. [Epub ahead of print]

PMID:
29986868
2.

Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis.

Remez LA, Onishi A, Menuchin-Lasowski Y, Biran A, Blackshaw S, Wahlin KJ, Zack DJ, Ashery-Padan R.

Dev Biol. 2017 Dec 1;432(1):140-150. doi: 10.1016/j.ydbio.2017.09.030. Epub 2017 Oct 7.

3.

The retinal pigmented epithelium - from basic developmental biology research to translational approaches.

Amram B, Cohen-Tayar Y, David A, Ashery-Padan R.

Int J Dev Biol. 2017;61(3-4-5):225-234. doi: 10.1387/ijdb.160393ra. Review.

4.

Phosphatidylserine Ameliorates Neurodegenerative Symptoms and Enhances Axonal Transport in a Mouse Model of Familial Dysautonomia.

Naftelberg S, Abramovitch Z, Gluska S, Yannai S, Joshi Y, Donyo M, Ben-Yaakov K, Gradus T, Zonszain J, Farhy C, Ashery-Padan R, Perlson E, Ast G.

PLoS Genet. 2016 Dec 20;12(12):e1006486. doi: 10.1371/journal.pgen.1006486. eCollection 2016 Dec.

5.

PAX6 maintains β cell identity by repressing genes of alternative islet cell types.

Swisa A, Avrahami D, Eden N, Zhang J, Feleke E, Dahan T, Cohen-Tayar Y, Stolovich-Rain M, Kaestner KH, Glaser B, Ashery-Padan R, Dor Y.

J Clin Invest. 2017 Jan 3;127(1):230-243. doi: 10.1172/JCI88015. Epub 2016 Dec 12.

6.

The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis.

Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R.

Development. 2016 Nov 15;143(22):4182-4192. Epub 2016 Oct 3.

7.

Pax6 associates with H3K4-specific histone methyltransferases Mll1, Mll2, and Set1a and regulates H3K4 methylation at promoters and enhancers.

Sun J, Zhao Y, McGreal R, Cohen-Tayar Y, Rockowitz S, Wilczek C, Ashery-Padan R, Shechter D, Zheng D, Cvekl A.

Epigenetics Chromatin. 2016 Sep 9;9(1):37. doi: 10.1186/s13072-016-0087-z. eCollection 2016.

8.

mSWI/SNF (BAF) Complexes Are Indispensable for the Neurogenesis and Development of Embryonic Olfactory Epithelium.

Bachmann C, Nguyen H, Rosenbusch J, Pham L, Rabe T, Patwa M, Sokpor G, Seong RH, Ashery-Padan R, Mansouri A, Stoykova A, Staiger JF, Tuoc T.

PLoS Genet. 2016 Sep 9;12(9):e1006274. doi: 10.1371/journal.pgen.1006274. eCollection 2016 Sep.

9.

Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals.

Menuchin-Lasowski Y, Oren-Giladi P, Xie Q, Ezra-Elia R, Ofri R, Peled-Hajaj S, Farhy C, Higashi Y, Van de Putte T, Kondoh H, Huylebroeck D, Cvekl A, Ashery-Padan R.

Development. 2016 Aug 1;143(15):2829-41. doi: 10.1242/dev.136101. Epub 2016 Jul 6.

10.

Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation.

He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H Jr, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, Stopka T, Cvekl A.

Development. 2016 Jun 1;143(11):1937-47. doi: 10.1242/dev.135285.

11.

Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development.

Sun J, Rockowitz S, Xie Q, Ashery-Padan R, Zheng D, Cvekl A.

Nucleic Acids Res. 2015 Aug 18;43(14):6827-46. doi: 10.1093/nar/gkv589. Epub 2015 Jul 2.

12.

MicroRNAs are essential for differentiation of the retinal pigmented epithelium and maturation of adjacent photoreceptors.

Ohana R, Weiman-Kelman B, Raviv S, Tamm ER, Pasmanik-Chor M, Rinon A, Netanely D, Shamir R, Solomon AS, Ashery-Padan R.

Development. 2015 Jul 15;142(14):2487-98. doi: 10.1242/dev.121533. Epub 2015 Jun 10.

13.

Wnt ligands from the embryonic surface ectoderm regulate 'bimetallic strip' optic cup morphogenesis in mouse.

Carpenter AC, Smith AN, Wagner H, Cohen-Tayar Y, Rao S, Wallace V, Ashery-Padan R, Lang RA.

Development. 2015 Mar 1;142(5):972-82. doi: 10.1242/dev.120022.

14.

Lack of centrioles and primary cilia in STIL(-/-) mouse embryos.

David A, Liu F, Tibelius A, Vulprecht J, Wald D, Rothermel U, Ohana R, Seitel A, Metzger J, Ashery-Padan R, Meinzer HP, Gröne HJ, Izraeli S, Krämer A.

Cell Cycle. 2014;13(18):2859-68. doi: 10.4161/15384101.2014.946830.

15.

The cellular and molecular mechanisms of vertebrate lens development.

Cvekl A, Ashery-Padan R.

Development. 2014 Dec;141(23):4432-47. doi: 10.1242/dev.107953. Epub 2014 Nov 18. Review.

16.

Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression.

Benavente CA, Finkelstein D, Johnson DA, Marine JC, Ashery-Padan R, Dyer MA.

Oncotarget. 2014 Oct 30;5(20):9594-608.

17.

Protein phosphatase magnesium dependent 1A governs the wound healing-inflammation-angiogenesis cross talk on injury.

Dvashi Z, Sar Shalom H, Shohat M, Ben-Meir D, Ferber S, Satchi-Fainaro R, Ashery-Padan R, Rosner M, Solomon AS, Lavi S.

Am J Pathol. 2014 Nov;184(11):2936-50. doi: 10.1016/j.ajpath.2014.07.022. Epub 2014 Sep 6.

PMID:
25196308
18.

PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF.

Raviv S, Bharti K, Rencus-Lazar S, Cohen-Tayar Y, Schyr R, Evantal N, Meshorer E, Zilberberg A, Idelson M, Reubinoff B, Grebe R, Rosin-Arbesfeld R, Lauderdale J, Lutty G, Arnheiter H, Ashery-Padan R.

PLoS Genet. 2014 May 29;10(5):e1004360. doi: 10.1371/journal.pgen.1004360. eCollection 2014.

19.

Identification and characterization of FGF2-dependent mRNA: microRNA networks during lens fiber cell differentiation.

Wolf L, Gao CS, Gueta K, Xie Q, Chevallier T, Podduturi NR, Sun J, Conte I, Zelenka PS, Ashery-Padan R, Zavadil J, Cvekl A.

G3 (Bethesda). 2013 Dec 9;3(12):2239-55. doi: 10.1534/g3.113.008698.

20.

Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells.

Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R.

PLoS One. 2013 Sep 20;8(9):e76489. doi: 10.1371/journal.pone.0076489. eCollection 2013.

21.

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.

Wolf L, Harrison W, Huang J, Xie Q, Xiao N, Sun J, Kong L, Lachke SA, Kuracha MR, Govindarajan V, Brindle PK, Ashery-Padan R, Beebe DC, Overbeek PA, Cvekl A.

Nucleic Acids Res. 2013 Dec;41(22):10199-214. doi: 10.1093/nar/gkt824. Epub 2013 Sep 12.

22.

Sensory cortex limits cortical maps and drives top-down plasticity in thalamocortical circuits.

Zembrzycki A, Chou SJ, Ashery-Padan R, Stoykova A, O'Leary DD.

Nat Neurosci. 2013 Aug;16(8):1060-7. doi: 10.1038/nn.3454. Epub 2013 Jul 7.

23.

Pax6 regulates gene expression in the vertebrate lens through miR-204.

Shaham O, Gueta K, Mor E, Oren-Giladi P, Grinberg D, Xie Q, Cvekl A, Shomron N, Davis N, Keydar-Prizant M, Raviv S, Pasmanik-Chor M, Bell RE, Levy C, Avellino R, Banfi S, Conte I, Ashery-Padan R.

PLoS Genet. 2013;9(3):e1003357. doi: 10.1371/journal.pgen.1003357. Epub 2013 Mar 14.

24.

Phosphatidylserine increases IKBKAP levels in a humanized knock-in IKBKAP mouse model.

Bochner R, Ziv Y, Zeevi D, Donyo M, Abraham L, Ashery-Padan R, Ast G.

Hum Mol Genet. 2013 Jul 15;22(14):2785-94. doi: 10.1093/hmg/ddt126. Epub 2013 Mar 20.

PMID:
23515154
25.

Pax6: a multi-level regulator of ocular development.

Shaham O, Menuchin Y, Farhy C, Ashery-Padan R.

Prog Retin Eye Res. 2012 Sep;31(5):351-76. doi: 10.1016/j.preteyeres.2012.04.002. Epub 2012 May 3. Review.

PMID:
22561546
26.

Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium.

Magenheim J, Klein AM, Stanger BZ, Ashery-Padan R, Sosa-Pineda B, Gu G, Dor Y.

Dev Biol. 2011 Nov 1;359(1):26-36. doi: 10.1016/j.ydbio.2011.08.006. Epub 2011 Aug 17.

27.

The mechanism of lens placode formation: a case of matrix-mediated morphogenesis.

Huang J, Rajagopal R, Liu Y, Dattilo LK, Shaham O, Ashery-Padan R, Beebe DC.

Dev Biol. 2011 Jul 1;355(1):32-42. doi: 10.1016/j.ydbio.2011.04.008. Epub 2011 Apr 21.

28.

Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium.

Davis N, Mor E, Ashery-Padan R.

Development. 2011 Jan;138(1):127-38. doi: 10.1242/dev.053637.

29.

Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation.

He S, Pirity MK, Wang WL, Wolf L, Chauhan BK, Cveklova K, Tamm ER, Ashery-Padan R, Metzger D, Nakai A, Chambon P, Zavadil J, Cvekl A.

Epigenetics Chromatin. 2010 Nov 30;3(1):21. doi: 10.1186/1756-8935-3-21.

30.

Homozygosity mapping reveals null mutations in FAM161A as a cause of autosomal-recessive retinitis pigmentosa.

Bandah-Rozenfeld D, Mizrahi-Meissonnier L, Farhy C, Obolensky A, Chowers I, Pe'er J, Merin S, Ben-Yosef T, Ashery-Padan R, Banin E, Sharon D.

Am J Hum Genet. 2010 Sep 10;87(3):382-91. doi: 10.1016/j.ajhg.2010.07.022. Epub 2010 Aug 12.

31.

Reduced expression of Pax6 in lens and cornea of mutant mice leads to failure of chamber angle development and juvenile glaucoma.

Kroeber M, Davis N, Holzmann S, Kritzenberger M, Shelah-Goraly M, Ofri R, Ashery-Padan R, Tamm ER.

Hum Mol Genet. 2010 Sep 1;19(17):3332-42. doi: 10.1093/hmg/ddq237. Epub 2010 Jun 10.

PMID:
20538882
32.

Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis.

Smith AN, Miller LA, Radice G, Ashery-Padan R, Lang RA.

Development. 2009 Sep;136(17):2977-85. doi: 10.1242/dev.037341. Erratum in: Development. 2009 Oct;136(19):3377.

33.

Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice.

Tuoc TC, Radyushkin K, Tonchev AB, Piñon MC, Ashery-Padan R, Molnár Z, Davidoff MS, Stoykova A.

J Neurosci. 2009 Jul 1;29(26):8335-49. doi: 10.1523/JNEUROSCI.5669-08.2009.

34.

Pax6 is essential for lens fiber cell differentiation.

Shaham O, Smith AN, Robinson ML, Taketo MM, Lang RA, Ashery-Padan R.

Development. 2009 Aug;136(15):2567-78. doi: 10.1242/dev.032888. Epub 2009 Jul 1.

35.

Pax6 dosage requirements in iris and ciliary body differentiation.

Davis N, Yoffe C, Raviv S, Antes R, Berger J, Holzmann S, Stoykova A, Overbeek PA, Tamm ER, Ashery-Padan R.

Dev Biol. 2009 Sep 1;333(1):132-42. doi: 10.1016/j.ydbio.2009.06.023. Epub 2009 Jun 27.

36.

Conditional inactivation of the NBS1 gene in the mouse central nervous system leads to neurodegeneration and disorganization of the visual system.

Baranes K, Raz-Prag D, Nitzan A, Galron R, Ashery-Padan R, Rotenstreich Y, Assaf Y, Shiloh Y, Wang ZQ, Barzilai A, Solomon AS.

Exp Neurol. 2009 Jul;218(1):24-32. doi: 10.1016/j.expneurol.2009.03.026. Epub 2009 Apr 1.

PMID:
19345213
37.

In vivo MRI of altered brain anatomy and fiber connectivity in adult pax6 deficient mice.

Boretius S, Michaelis T, Tammer R, Ashery-Padan R, Frahm J, Stoykova A.

Cereb Cortex. 2009 Dec;19(12):2838-47. doi: 10.1093/cercor/bhp057. Epub 2009 Mar 27.

PMID:
19329571
38.

Dual requirement for Pax6 in retinal progenitor cells.

Oron-Karni V, Farhy C, Elgart M, Marquardt T, Remizova L, Yaron O, Xie Q, Cvekl A, Ashery-Padan R.

Development. 2008 Dec;135(24):4037-4047. doi: 10.1242/dev.028308. Epub 2008 Nov 12.

39.

Altered molecular regionalization and normal thalamocortical connections in cortex-specific Pax6 knock-out mice.

Piñon MC, Tuoc TC, Ashery-Padan R, Molnár Z, Stoykova A.

J Neurosci. 2008 Aug 27;28(35):8724-34. doi: 10.1523/JNEUROSCI.2565-08.2008.

40.

A dlx2- and pax6-dependent transcriptional code for periglomerular neuron specification in the adult olfactory bulb.

Brill MS, Snapyan M, Wohlfrom H, Ninkovic J, Jawerka M, Mastick GS, Ashery-Padan R, Saghatelyan A, Berninger B, Götz M.

J Neurosci. 2008 Jun 18;28(25):6439-52. doi: 10.1523/JNEUROSCI.0700-08.2008.

41.

Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype.

Pontoriero GF, Deschamps P, Ashery-Padan R, Wong R, Yang Y, Zavadil J, Cvekl A, Sullivan S, Williams T, West-Mays JA.

Dev Dyn. 2008 Mar;237(3):602-17. doi: 10.1002/dvdy.21445.

42.

Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing.

Alberstein M, Amit M, Vaknin K, O'Donnell A, Farhy C, Lerenthal Y, Shomron N, Shaham O, Sharrocks AD, Ashery-Padan R, Ast G.

RNA. 2007 Nov;13(11):1988-99. Epub 2007 Sep 5.

43.

Expression of the homeodomain transcription factor Meis2 in the embryonic and postnatal retina.

Bumsted-O'Brien KM, Hendrickson A, Haverkamp S, Ashery-Padan R, Schulte D.

J Comp Neurol. 2007 Nov 1;505(1):58-72.

PMID:
17729288
44.

CAMTAs: calmodulin-binding transcription activators from plants to human.

Finkler A, Ashery-Padan R, Fromm H.

FEBS Lett. 2007 Aug 21;581(21):3893-8. Epub 2007 Aug 1. Review.

45.

Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas.

Strom A, Bonal C, Ashery-Padan R, Hashimoto N, Campos ML, Trumpp A, Noda T, Kido Y, Real FX, Thorel F, Herrera PL.

Development. 2007 Aug;134(15):2719-25. Epub 2007 Jun 27.

46.

Iris development in vertebrates; genetic and molecular considerations.

Davis-Silberman N, Ashery-Padan R.

Brain Res. 2008 Feb 4;1192:17-28. Epub 2007 Mar 20. Review.

PMID:
17466284
47.

The proliferation and expansion of retinal stem cells require functional Pax6.

Xu S, Sunderland ME, Coles BL, Kam A, Holowacz T, Ashery-Padan R, Marquardt T, McInnes RR, van der Kooy D.

Dev Biol. 2007 Apr 15;304(2):713-21. Epub 2007 Jan 19.

48.

Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells.

Swamynathan SK, Katz JP, Kaestner KH, Ashery-Padan R, Crawford MA, Piatigorsky J.

Mol Cell Biol. 2007 Jan;27(1):182-94. Epub 2006 Oct 23.

49.

Notch1 functions to suppress cone-photoreceptor fate specification in the developing mouse retina.

Yaron O, Farhy C, Marquardt T, Applebury M, Ashery-Padan R.

Development. 2006 Apr;133(7):1367-78. Epub 2006 Mar 1.

50.

Targeted deletion of AP-2alpha leads to disruption in corneal epithelial cell integrity and defects in the corneal stroma.

Dwivedi DJ, Pontoriero GF, Ashery-Padan R, Sullivan S, Williams T, West-Mays JA.

Invest Ophthalmol Vis Sci. 2005 Oct;46(10):3623-30.

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