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Items: 1 to 50 of 132

1.

Morphological localisation of sulfonylurea receptor 1 in endocrine cells of human, mouse and rat pancreas.

Guiot Y, Stevens M, Marhfour I, Stiernet P, Mikhailov M, Ashcroft SJH, Rahier J, Henquin JC, Sempoux C.

Diabetologia. 2007 Sep;50(9):1889-1899. doi: 10.1007/s00125-007-0731-z. Epub 2007 Jun 26.

PMID:
17593344
2.

A tribute to the life and work of Philip Randle.

Denton RM, Ashcroft SJ.

Diabetologia. 2007 Jul;50(7):1359-61. No abstract available.

PMID:
17473914
3.

Effect of creatine on the pancreatic beta-cell.

Rocić B, Lovrencić MV, Poje M, Ashcroft SJ.

Exp Clin Endocrinol Diabetes. 2007 Jan;115(1):29-32.

PMID:
17286231
4.

Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and beta cells.

Yamasaki M, Masgrau R, Morgan AJ, Churchill GC, Patel S, Ashcroft SJ, Galione A.

J Biol Chem. 2004 Feb 20;279(8):7234-40. Epub 2003 Dec 2.

5.

NAADP: a new second messenger for glucose-induced Ca2+ responses in clonal pancreatic beta cells.

Masgrau R, Churchill GC, Morgan AJ, Ashcroft SJ, Galione A.

Curr Biol. 2003 Feb 4;13(3):247-51.

6.

A novel simple method for the investigation of drug binding to the K(ATP) channel sulfonylurea receptor.

Mikhailova EA, Ashcroft SJ, Mikhailov MV.

Anal Biochem. 2002 Aug 15;307(2):383-5. No abstract available.

PMID:
12202259
7.

Human calcium/calmodulin-dependent protein kinase II gamma gene (CAMK2G): cloning, genomic structure and detection of variants in subjects with type II diabetes.

Gloyn AL, Desai M, Clark A, Levy JC, Holman RR, Frayling TM, Hattersley AT, Ashcroft SJ.

Diabetologia. 2002 Apr;45(4):580-3.

PMID:
12032636
8.

Structure-function relationships in the beta-cell K(ATP) channel.

Mikhailov MV, Mikhailova EA, Ashcroft SJ.

Biochem Soc Trans. 2002 Apr;30(2):323-7.

PMID:
12023873
9.
10.

Acute effects of fatty acids on insulin secretion from rat and human islets of Langerhans.

Gravena C, Mathias PC, Ashcroft SJ.

J Endocrinol. 2002 Apr;173(1):73-80.

PMID:
11927386
12.

Molecular structure of the glibenclamide binding site of the beta-cell K(ATP) channel.

Mikhailov MV, Mikhailova EA, Ashcroft SJ.

FEBS Lett. 2001 Jun 15;499(1-2):154-60.

13.

Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53).

Gloyn AL, Hashim Y, Ashcroft SJ, Ashfield R, Wiltshire S, Turner RC; UK Prospective Diabetes Study (UKPDS 53).

Diabet Med. 2001 Mar;18(3):206-12. Erratum in: Diabet Med. 2003 Mar;20(3):252..

PMID:
11318841
14.

Investigation of the molecular assembly of beta-cell K(ATP) channels.

Mikhailov MV, Mikhailova EA, Ashcroft SJ.

FEBS Lett. 2000 Sep 29;482(1-2):59-64.

15.

The beta-cell K(ATP) channel.

Ashcroft SJ.

J Membr Biol. 2000 Aug 1;176(3):187-206. Review. No abstract available.

PMID:
10931971
16.
17.
18.

Human islets of Langerhans express the delta(C) isoform of calcium/calmodulin-dependent protein kinase II.

Southam L, Ashfield R, Cox R, Lathrop M, Ashcroft SJ.

Diabetes Metab Res Rev. 1999 Jul-Aug;15(4):243-6.

PMID:
10495472
19.

Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel.

Ashfield R, Gribble FM, Ashcroft SJ, Ashcroft FM.

Diabetes. 1999 Jun;48(6):1341-7.

PMID:
10342826
20.
21.
22.
23.

Cloning of the promoters for the beta-cell ATP-sensitive K-channel subunits Kir6.2 and SUR1.

Ashfield R, Ashcroft SJ.

Diabetes. 1998 Aug;47(8):1274-80.

PMID:
9703328
24.

Expression of functionally active ATP-sensitive K-channels in insect cells using baculovirus.

Mikhailov MV, Proks P, Ashcroft FM, Ashcroft SJ.

FEBS Lett. 1998 Jun 16;429(3):390-4.

25.

Glucose modulation of ATP-sensitive K-currents in wild-type, homozygous and heterozygous glucokinase knock-out mice.

Sakura H, Ashcroft SJ, Terauchi Y, Kadowaki T, Ashcroft FM.

Diabetologia. 1998 Jun;41(6):654-9.

PMID:
9662046
26.

Human islets of Langerhans express multiple isoforms of calcium/calmodulin-dependent protein kinase II.

Breen MA, Ashcroft SJ.

Biochem Biophys Res Commun. 1997 Jul 18;236(2):473-8.

PMID:
9240463
27.

Plasma uric acid and total antioxidant status in patients with diabetes mellitus.

Vucić M, Rocić B, Bozikov V, Ashcroft SJ.

Horm Metab Res. 1997 Jul;29(7):355-7. No abstract available.

PMID:
9288569
28.

Superoxide dismutase activity in lymphocytes and polymorphonuclear cells of diabetic patients.

Vucić M, Gavella M, Bozikov V, Ashcroft SJ, Rocić B.

Eur J Clin Chem Clin Biochem. 1997 Jul;35(7):517-21.

PMID:
9263727
30.

Trans-acting factor(s) confer glucose-responsive transcriptional regulation in the insulin gene.

Goodison S, Ashcroft SJ.

Adv Exp Med Biol. 1997;426:97-100. No abstract available.

PMID:
9544261
31.

Molecular cloning of the cDNA encoding beta-cell calcium/calmodulin-dependent protein kinase II.

Urquidi V, Ashcroft SJ.

Adv Exp Med Biol. 1997;426:91-6. No abstract available.

PMID:
9544260
32.

Intracellular second messengers.

Ashcroft SJ.

Adv Exp Med Biol. 1997;426:73-80. Review. No abstract available.

PMID:
9544257
33.

Effects of protein phosphorylation on the sulphonylurea receptor of the pancreatic beta-cell.

Niki I, Coles B, Ashcroft FM, Ashcroft SJ.

Adv Exp Med Biol. 1997;426:59-69. No abstract available.

PMID:
9544256
34.

Isoforms of endoplasmic reticulum Ca(2+)-ATPase are differentially expressed in normal and diabetic islets of Langerhans.

Váradi A, Molnár E, Ostenson CG, Ashcroft SJ.

Biochem J. 1996 Oct 15;319 ( Pt 2):521-7.

35.

Protein kinase C in beta-cells: expression of multiple isoforms and involvement in cholinergic stimulation of insulin secretion.

Tian YM, Urquidi V, Ashcroft SJ.

Mol Cell Endocrinol. 1996 May 31;119(2):185-93. Erratum in: Mol Cell Endocrinol 1996 Jul 1;120(2):221.

PMID:
8807638
36.
37.

Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels.

Ammälä C, Moorhouse A, Gribble F, Ashfield R, Proks P, Smith PA, Sakura H, Coles B, Ashcroft SJ, Ashcroft FM.

Nature. 1996 Feb 8;379(6565):545-8.

PMID:
8596634
38.

Identification of functional ionotropic glutamate receptor proteins in pancreatic beta-cells and in islets of Langerhans.

Molnár E, Váradi A, McIlhinney RA, Ashcroft SJ.

FEBS Lett. 1995 Sep 11;371(3):253-7.

39.
41.

Protein phosphorylation and beta-cell function.

Ashcroft SJ.

Diabetologia. 1994 Sep;37 Suppl 2:S21-9. Review.

PMID:
7821735
42.

Response to glucose of transcription factor binding to the rat insulin-1 gene promoter.

Goodison S, Miyazaki J, Ashcroft SJ.

Biochem Biophys Res Commun. 1994 Aug 30;203(1):702-10.

PMID:
8074725
43.

Differential expression of the inwardly-rectifying K-channel ROMK1 in rat brain.

Kenna S, Röper J, Ho K, Hebert S, Ashcroft SJ, Ashcroft FM.

Brain Res Mol Brain Res. 1994 Jul;24(1-4):353-6.

PMID:
7968375
44.

Determination of the molecular mass of the native beta-cell sulfonylurea receptor.

Skeer JM, Dégano P, Coles B, Potier M, Ashcroft FM, Ashcroft SJ.

FEBS Lett. 1994 Jan 24;338(1):98-102.

45.
46.

Characterization and solubilization of the sulphonylurea receptor in rat brain.

Niki I, Ashcroft SJ.

Neuropharmacology. 1993 Oct;32(10):951-7.

PMID:
8295717
47.

Human insulin promoter driven reporter gene expression.

Goodison S, Ashcroft SJ.

Biochem Soc Trans. 1993 Feb;21(1):22S. No abstract available.

PMID:
8449300
48.

Characterization of Ca2+/calmodulin-dependent protein kinase in rat pancreatic islets.

Hughes SJ, Smith H, Ashcroft SJ.

Biochem J. 1993 Feb 1;289 ( Pt 3):795-800.

49.

The beta-cell sulfonylurea receptor.

Ashcroft SJ, Niki I, Kenna S, Weng L, Skeer J, Coles B, Ashcroft FM.

Adv Exp Med Biol. 1993;334:47-61. Review. No abstract available.

PMID:
8249695
50.

The sulfonylurea receptor.

Ashcroft SJ, Ashcroft FM.

Biochim Biophys Acta. 1992 Dec 15;1175(1):45-59. Review. No abstract available.

PMID:
1482696

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