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Items: 1 to 50 of 56

1.

Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment.

Perkins EJ, Ashauer R, Burgoon L, Conolly R, Landesmann B, Mackay C, Murphy CA, Pollesch N, Wheeler JR, Zupanic A, Scholz S.

Environ Toxicol Chem. 2019 Sep;38(9):1850-1865. doi: 10.1002/etc.4505. Epub 2019 Aug 8. Review.

PMID:
31127958
2.

Factors Affecting the Growth of Pseudokirchneriella subcapitata in Single-Species Tests: Lessons for the Experimental Design and the Reproducibility of a Multitrophic Laboratory Microcosm.

Riedl V, Agatz A, Benstead R, Ashauer R.

Environ Toxicol Chem. 2019 May;38(5):1120-1131. doi: 10.1002/etc.4393. Epub 2019 Apr 1.

PMID:
30779376
3.

Automated, high-throughput measurement of size and growth curves of small organisms in well plates.

Duckworth J, Jager T, Ashauer R.

Sci Rep. 2019 Jan 9;9(1):10. doi: 10.1038/s41598-018-36877-0.

4.

Quantifying pesticide deposits and spray patterns at micro-scales on apple (Malus domesticus) leaves with a view to arthropod exposure.

Witton JT, Pickering MD, Alvarez T, Reed M, Weyman G, Hodson ME, Ashauer R.

Pest Manag Sci. 2018 Dec;74(12):2884-2893. doi: 10.1002/ps.5136. Epub 2018 Sep 4.

5.

How to Evaluate the Quality of Toxicokinetic-Toxicodynamic Models in the Context of Environmental Risk Assessment.

Jager T, Ashauer R.

Integr Environ Assess Manag. 2018 Sep;14(5):604-614. doi: 10.1002/ieam.2026. Epub 2018 Mar 24.

6.

A standardized tritrophic small-scale system (TriCosm) for the assessment of stressor-induced effects on aquatic community dynamics.

Riedl V, Agatz A, Benstead R, Ashauer R.

Environ Toxicol Chem. 2018 Apr;37(4):1051-1060. doi: 10.1002/etc.4032. Epub 2018 Jan 5.

7.

Physiological modes of action across species and toxicants: the key to predictive ecotoxicology.

Ashauer R, Jager T.

Environ Sci Process Impacts. 2018 Jan 24;20(1):48-57. doi: 10.1039/c7em00328e.

PMID:
29090718
8.

Prediction of pest pressure on corn root nodes: the POPP-Corn model.

Agatz A, Ashauer R, Sweeney P, Brown CD.

J Pest Sci (2004). 2017;90(1):161-172. doi: 10.1007/s10340-016-0788-x. Epub 2016 Jun 21.

9.

Toxic Mixtures in Time-The Sequence Makes the Poison.

Ashauer R, O'Connor I, Escher BI.

Environ Sci Technol. 2017 Mar 7;51(5):3084-3092. doi: 10.1021/acs.est.6b06163. Epub 2017 Feb 17.

10.

Integrated presentation of ecological risk from multiple stressors.

Goussen B, Price OR, Rendal C, Ashauer R.

Sci Rep. 2016 Oct 26;6:36004. doi: 10.1038/srep36004.

11.
12.

Reintroducing Environmental Change Drivers in Biodiversity-Ecosystem Functioning Research.

De Laender F, Rohr JR, Ashauer R, Baird DJ, Berger U, Eisenhauer N, Grimm V, Hommen U, Maltby L, Meliàn CJ, Pomati F, Roessink I, Radchuk V, Van den Brink PJ.

Trends Ecol Evol. 2016 Dec;31(12):905-915. doi: 10.1016/j.tree.2016.09.007. Epub 2016 Oct 11. Review.

13.

Modelling survival: exposure pattern, species sensitivity and uncertainty.

Ashauer R, Albert C, Augustine S, Cedergreen N, Charles S, Ducrot V, Focks A, Gabsi F, Gergs A, Goussen B, Jager T, Kramer NI, Nyman AM, Poulsen V, Reichenberger S, Schäfer RB, Van den Brink PJ, Veltman K, Vogel S, Zimmer EI, Preuss TG.

Sci Rep. 2016 Jul 6;6:29178. doi: 10.1038/srep29178.

14.

Computationally Efficient Implementation of a Novel Algorithm for the General Unified Threshold Model of Survival (GUTS).

Albert C, Vogel S, Ashauer R.

PLoS Comput Biol. 2016 Jun 24;12(6):e1004978. doi: 10.1371/journal.pcbi.1004978. eCollection 2016 Jun.

15.

Toward refined environmental scenarios for ecological risk assessment of down-the-drain chemicals in freshwater environments.

Franco A, Price OR, Marshall S, Jolliet O, Van den Brink PJ, Rico A, Focks A, De Laender F, Ashauer R.

Integr Environ Assess Manag. 2017 Mar;13(2):233-248. doi: 10.1002/ieam.1801. Epub 2016 Aug 10. Review.

16.

Toxicology across scales: Cell population growth in vitro predicts reduced fish growth.

Stadnicka-Michalak J, Schirmer K, Ashauer R.

Sci Adv. 2015 Aug 7;1(7):e1500302. doi: 10.1126/sciadv.1500302. eCollection 2015 Aug.

17.

Death Dilemma and Organism Recovery in Ecotoxicology.

Ashauer R, O'Connor I, Hintermeister A, Escher BI.

Environ Sci Technol. 2015 Aug 18;49(16):10136-46. doi: 10.1021/acs.est.5b03079. Epub 2015 Jul 29.

18.

Using toxicokinetic-toxicodynamic modeling as an acute risk assessment refinement approach in vertebrate ecological risk assessment.

Ducrot V, Ashauer R, Bednarska AJ, Hinarejos S, Thorbek P, Weyman G.

Integr Environ Assess Manag. 2016 Jan;12(1):32-45. doi: 10.1002/ieam.1641. Epub 2015 Jun 11.

PMID:
25833822
19.

Minimised bioconcentration tests: a useful tool for assessing chemical uptake into terrestrial and aquatic invertebrates?

Carter LJ, Ashauer R, Ryan JJ, Boxall AB.

Environ Sci Technol. 2014 Nov 18;48(22):13497-503. doi: 10.1021/es5031992. Epub 2014 Nov 6.

20.

Importance of toxicokinetics for interspecies variation in sensitivity to chemicals.

Nyman AM, Schirmer K, Ashauer R.

Environ Sci Technol. 2014 May 20;48(10):5946-54. doi: 10.1021/es5005126. Epub 2014 May 2.

PMID:
24758734
21.

Nanopesticides: guiding principles for regulatory evaluation of environmental risks.

Kookana RS, Boxall AB, Reeves PT, Ashauer R, Beulke S, Chaudhry Q, Cornelis G, Fernandes TF, Gan J, Kah M, Lynch I, Ranville J, Sinclair C, Spurgeon D, Tiede K, Van den Brink PJ.

J Agric Food Chem. 2014 May 14;62(19):4227-40. doi: 10.1021/jf500232f. Epub 2014 Apr 30. Review.

22.

Measured and modeled toxicokinetics in cultured fish cells and application to in vitro-in vivo toxicity extrapolation.

Stadnicka-Michalak J, Tanneberger K, Schirmer K, Ashauer R.

PLoS One. 2014 Mar 19;9(3):e92303. doi: 10.1371/journal.pone.0092303. eCollection 2014.

23.

Imidacloprid perturbs feeding of Gammarus pulex at environmentally relevant concentrations.

Agatz A, Ashauer R, Brown CD.

Environ Toxicol Chem. 2014 Mar;33(3):648-53. doi: 10.1002/etc.2480. Epub 2014 Jan 24.

PMID:
24375767
24.

Modeling the contribution of toxicokinetic and toxicodynamic processes to the recovery of Gammarus pulex populations after exposure to pesticides.

Galic N, Ashauer R, Baveco H, Nyman AM, Barsi A, Thorbek P, Bruns E, Van den Brink PJ.

Environ Toxicol Chem. 2014 Jul;33(7):1476-88. doi: 10.1002/etc.2481. Epub 2014 May 9.

PMID:
24307654
25.

Bioconcentration of organic contaminants in Daphnia resting eggs.

Chiaia-Hernandez AC, Ashauer R, Moest M, Hollingshaus T, Jeon J, Spaak P, Hollender J.

Environ Sci Technol. 2013 Sep 17;47(18):10667-75. doi: 10.1021/es401763d. Epub 2013 Sep 9.

PMID:
23919732
26.

Comparative toxicokinetics of organic micropollutants in freshwater crustaceans.

Jeon J, Kurth D, Ashauer R, Hollender J.

Environ Sci Technol. 2013 Aug 6;47(15):8809-17. doi: 10.1021/es400833g. Epub 2013 Jul 12.

PMID:
23755888
27.

The insecticide imidacloprid causes mortality of the freshwater amphipod Gammarus pulex by interfering with feeding behavior.

Nyman AM, Hintermeister A, Schirmer K, Ashauer R.

PLoS One. 2013 May 15;8(5):e62472. doi: 10.1371/journal.pone.0062472. Print 2013.

28.

Highly time-variable exposure to chemicals--toward an assessment strategy.

Ashauer R, Brown CD.

Integr Environ Assess Manag. 2013 Jul;9(3):e27-33. doi: 10.1002/ieam.1421. Epub 2013 Jun 25.

PMID:
23564608
29.

A method to predict and understand fish survival under dynamic chemical stress using standard ecotoxicity data.

Ashauer R, Thorbek P, Warinton JS, Wheeler JR, Maund S.

Environ Toxicol Chem. 2013 Apr;32(4):954-65. doi: 10.1002/etc.2144. Epub 2013 Mar 4.

30.

Effects of repeated pulsed herbicide exposures on the growth of aquatic macrophytes.

Boxall AB, Fogg LA, Ashauer R, Bowles T, Sinclair CJ, Colyer A, Brain RA.

Environ Toxicol Chem. 2013 Jan;32(1):193-200. doi: 10.1002/etc.2040. Epub 2012 Nov 21.

PMID:
23109258
31.

Toxicokinetic and toxicodynamic model for diazinon toxicity--mechanistic explanation of differences in the sensitivity of Daphnia magna and Gammarus pulex.

Kretschmann A, Ashauer R, Hollender J, Escher BI.

Environ Toxicol Chem. 2012 Sep;31(9):2014-22. doi: 10.1002/etc.1905. Epub 2012 Jul 13.

PMID:
22653849
32.
33.

Predicting concentrations of organic chemicals in fish by using toxicokinetic models.

Stadnicka J, Schirmer K, Ashauer R.

Environ Sci Technol. 2012 Mar 20;46(6):3273-80. doi: 10.1021/es2043728. Epub 2012 Feb 28.

34.

Significance of xenobiotic metabolism for bioaccumulation kinetics of organic chemicals in Gammarus pulex.

Ashauer R, Hintermeister A, O'Connor I, Elumelu M, Hollender J, Escher BI.

Environ Sci Technol. 2012 Mar 20;46(6):3498-508. doi: 10.1021/es204611h. Epub 2012 Feb 28. Erratum in: Environ Sci Technol. 2012 Apr 17;46(8):4682.

35.

Uptake and depuration of pharmaceuticals in aquatic invertebrates.

Meredith-Williams M, Carter LJ, Fussell R, Raffaelli D, Ashauer R, Boxall AB.

Environ Pollut. 2012 Jun;165:250-8. doi: 10.1016/j.envpol.2011.11.029. Epub 2012 Jan 5.

PMID:
22226124
36.

Environmental risk assessment of fluctuating diazinon concentrations in an urban and agricultural catchment using toxicokinetic-toxicodynamic modeling.

Ashauer R, Wittmer I, Stamm C, Escher BI.

Environ Sci Technol. 2011 Nov 15;45(22):9783-92. doi: 10.1021/es202413a. Epub 2011 Oct 19.

37.

Toxicokinetic-toxicodynamic modeling of quantal and graded sublethal endpoints: a brief discussion of concepts.

Ashauer R, Agatz A, Albert C, Ducrot V, Galic N, Hendriks J, Jager T, Kretschmann A, O'Connor I, Rubach MN, Nyman AM, Schmitt W, Stadnicka J, van den Brink PJ, Preuss TG.

Environ Toxicol Chem. 2011 Nov;30(11):2519-24. doi: 10.1002/etc.639. Epub 2011 Aug 24.

PMID:
21805502
38.

Toxicokinetic model describing bioconcentration and biotransformation of diazinon in Daphnia magna.

Kretschmann A, Ashauer R, Preuss TG, Spaak P, Escher BI, Hollender J.

Environ Sci Technol. 2011 Jun 1;45(11):4995-5002. doi: 10.1021/es104324v. Epub 2011 May 11.

PMID:
21561125
39.

Mechanistic toxicodynamic model for receptor-mediated toxicity of diazoxon, the active metabolite of diazinon, in Daphnia magna.

Kretschmann A, Ashauer R, Hitzfeld K, Spaak P, Hollender J, Escher BI.

Environ Sci Technol. 2011 Jun 1;45(11):4980-7. doi: 10.1021/es1042386. Epub 2011 May 3.

PMID:
21539304
40.

Acute toxicity of organic chemicals to Gammarus pulex correlates with sensitivity of Daphnia magna across most modes of action.

Ashauer R, Hintermeister A, Potthoff E, Escher BI.

Aquat Toxicol. 2011 May;103(1-2):38-45. doi: 10.1016/j.aquatox.2011.02.002. Epub 2011 Feb 15.

PMID:
21392493
41.

General unified threshold model of survival--a toxicokinetic-toxicodynamic framework for ecotoxicology.

Jager T, Albert C, Preuss TG, Ashauer R.

Environ Sci Technol. 2011 Apr 1;45(7):2529-40. doi: 10.1021/es103092a. Epub 2011 Mar 2.

PMID:
21366215
42.

Crucial role of mechanisms and modes of toxic action for understanding tissue residue toxicity and internal effect concentrations of organic chemicals.

Escher BI, Ashauer R, Dyer S, Hermens JL, Lee JH, Leslie HA, Mayer P, Meador JP, Warne MS.

Integr Environ Assess Manag. 2011 Jan;7(1):28-49. doi: 10.1002/ieam.100. Review.

PMID:
21184568
43.

Framework for traits-based assessment in ecotoxicology.

Rubach MN, Ashauer R, Buchwalter DB, De Lange H, Hamer M, Preuss TG, Töpke K, Maund SJ.

Integr Environ Assess Manag. 2011 Apr;7(2):172-86. doi: 10.1002/ieam.105. Epub 2010 Jul 8.

PMID:
20981835
44.

Toxicokinetic variation in 15 freshwater arthropod species exposed to the insecticide chlorpyrifos.

Rubach MN, Ashauer R, Maund SJ, Baird DJ, Van den Brink PJ.

Environ Toxicol Chem. 2010 Oct;29(10):2225-34. doi: 10.1002/etc.273.

PMID:
20872686
45.

Advantages of toxicokinetic and toxicodynamic modelling in aquatic ecotoxicology and risk assessment.

Ashauer R, Escher BI.

J Environ Monit. 2010 Nov;12(11):2056-61. doi: 10.1039/c0em00234h. Epub 2010 Sep 23.

PMID:
20862435
46.

Bioaccumulation kinetics of organic xenobiotic pollutants in the freshwater invertebrate Gammarus pulex modeled with prediction intervals.

Ashauer R, Caravatti I, Hintermeister A, Escher BI.

Environ Toxicol Chem. 2010 Jul;29(7):1625-36. doi: 10.1002/etc.175.

PMID:
20821614
47.

Toxicokinetic and toxicodynamic modeling explains carry-over toxicity from exposure to diazinon by slow organism recovery.

Ashauer R, Hintermeister A, Caravatti I, Kretschmann A, Escher BI.

Environ Sci Technol. 2010 May 15;44(10):3963-71. doi: 10.1021/es903478b.

PMID:
20397634
48.

CREAM: a European project on mechanistic effect models for ecological risk assessment of chemicals.

Grimm V, Ashauer R, Forbes V, Hommen U, Preuss TG, Schmidt A, van den Brink PJ, Wogram J, Thorbek P.

Environ Sci Pollut Res Int. 2009 Sep;16(6):614-7. doi: 10.1007/s11356-009-0228-z. Epub 2009 Aug 7. No abstract available.

PMID:
19662448
49.

Mechanistic effect models for ecological risk assessment of chemicals (MEMoRisk)-a new SETAC-Europe Advisory Group.

Preuss TG, Hommen U, Alix A, Ashauer R, van den Brink P, Chapman P, Ducrot V, Forbes V, Grimm V, Schäfer D, Streissl F, Thorbek P.

Environ Sci Pollut Res Int. 2009 May;16(3):250-2. doi: 10.1007/s11356-009-0124-6. Epub 2009 Mar 26. No abstract available.

PMID:
19322598
50.

Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils.

Blackwell PA, Kay P, Ashauer R, Boxall AB.

Chemosphere. 2009 Mar;75(1):13-9. doi: 10.1016/j.chemosphere.2008.11.070. Epub 2009 Jan 6.

PMID:
19128817

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