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Items: 18


Kinesin-5 Promotes Microtubule Nucleation and Assembly by Stabilizing a Lattice-Competent Conformation of Tubulin.

Chen GY, Cleary JM, Asenjo AB, Chen Y, Mascaro JA, Arginteanu DFJ, Sosa H, Hancock WO.

Curr Biol. 2019 Jul 22;29(14):2259-2269.e4. doi: 10.1016/j.cub.2019.05.075. Epub 2019 Jul 4.


Author Correction: Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s.

Benoit MPMH, Asenjo AB, Sosa H.

Nat Commun. 2018 Jul 11;9(1):2748. doi: 10.1038/s41467-018-04858-6.


Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s.

Benoit MPMH, Asenjo AB, Sosa H.

Nat Commun. 2018 Apr 25;9(1):1662. doi: 10.1038/s41467-018-04044-8. Erratum in: Nat Commun. 2018 Jul 11;9(1):2748.


Distinct Interaction Modes of the Kinesin-13 Motor Domain with the Microtubule.

Chatterjee C, Benoit MPMH, DePaoli V, Diaz-Valencia JD, Asenjo AB, Gerfen GJ, Sharp DJ, Sosa H.

Biophys J. 2016 Apr 12;110(7):1593-1604. doi: 10.1016/j.bpj.2016.02.029.


KIF14 binds tightly to microtubules and adopts a rigor-like conformation.

Arora K, Talje L, Asenjo AB, Andersen P, Atchia K, Joshi M, Sosa H, Allingham JS, Kwok BH.

J Mol Biol. 2014 Aug 26;426(17):2997-3015. doi: 10.1016/j.jmb.2014.05.030. Epub 2014 Jun 17.


A second tubulin binding site on the kinesin-13 motor head domain is important during mitosis.

Zhang D, Asenjo AB, Greenbaum M, Xie L, Sharp DJ, Sosa H.

PLoS One. 2013 Aug 28;8(8):e73075. doi: 10.1371/journal.pone.0073075. eCollection 2013.


Structural model for tubulin recognition and deformation by kinesin-13 microtubule depolymerases.

Asenjo AB, Chatterjee C, Tan D, DePaoli V, Rice WJ, Diaz-Avalos R, Silvestry M, Sosa H.

Cell Rep. 2013 Mar 28;3(3):759-68. doi: 10.1016/j.celrep.2013.01.030. Epub 2013 Feb 21.


Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis.

Mukherjee S, Diaz Valencia JD, Stewman S, Metz J, Monnier S, Rath U, Asenjo AB, Charafeddine RA, Sosa HJ, Ross JL, Ma A, Sharp DJ.

Cell Cycle. 2012 Jun 15;11(12):2359-66. doi: 10.4161/cc.20849. Epub 2012 Jun 15.


Drosophila katanin is a microtubule depolymerase that regulates cortical-microtubule plus-end interactions and cell migration.

Zhang D, Grode KD, Stewman SF, Diaz-Valencia JD, Liebling E, Rath U, Riera T, Currie JD, Buster DW, Asenjo AB, Sosa HJ, Ross JL, Ma A, Rogers SL, Sharp DJ.

Nat Cell Biol. 2011 Apr;13(4):361-70. doi: 10.1038/ncb2206. Epub 2011 Mar 6.


Structure and dynamics of the kinesin-microtubule interaction revealed by fluorescence polarization microscopy.

Sosa H, Asenjo AB, Peterman EJ.

Methods Cell Biol. 2010;95:505-19. doi: 10.1016/S0091-679X(10)95025-5. Review.


Motor domain phosphorylation and regulation of the Drosophila kinesin 13, KLP10A.

Mennella V, Tan DY, Buster DW, Asenjo AB, Rath U, Ma A, Sosa HJ, Sharp DJ.

J Cell Biol. 2009 Aug 24;186(4):481-90. doi: 10.1083/jcb.200902113. Epub 2009 Aug 17.


A mobile kinesin-head intermediate during the ATP-waiting state.

Asenjo AB, Sosa H.

Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5657-62. doi: 10.1073/pnas.0808355106. Epub 2009 Mar 25.


Kinesin-13s form rings around microtubules.

Tan D, Asenjo AB, Mennella V, Sharp DJ, Sosa H.

J Cell Biol. 2006 Oct 9;175(1):25-31. Epub 2006 Oct 2.


Nucleotide binding and hydrolysis induces a disorder-order transition in the kinesin neck-linker region.

Asenjo AB, Weinberg Y, Sosa H.

Nat Struct Mol Biol. 2006 Jul;13(7):648-54. Epub 2006 Jun 18.


Configuration of the two kinesin motor domains during ATP hydrolysis.

Asenjo AB, Krohn N, Sosa H.

Nat Struct Biol. 2003 Oct;10(10):836-42. Epub 2003 Sep 14.


Molecular determinants of human red/green color discrimination.

Asenjo AB, Rim J, Oprian DD.

Neuron. 1994 May;12(5):1131-8.


Identification of the Cl(-)-binding site in the human red and green color vision pigments.

Wang Z, Asenjo AB, Oprian DD.

Biochemistry. 1993 Mar 9;32(9):2125-30.


Design, chemical synthesis, and expression of genes for the three human color vision pigments.

Oprian DD, Asenjo AB, Lee N, Pelletier SL.

Biochemistry. 1991 Dec 3;30(48):11367-72.


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