Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
2000 2
2004 1
2005 1
2010 1
2012 1
2016 1
2017 2
2018 1
2019 1
2020 1
2021 4
2022 7
2023 9
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

32 results

Results by year

Filters applied: . Clear all
Page 1
Exosomal lncRNA TUG1 derived from human urine-derived stem cells attenuates renal ischemia/reperfusion injury by interacting with SRSF1 to regulate ASCL4-mediated ferroptosis.
Sun Z, Wu J, Bi Q, Wang W. Sun Z, et al. Stem Cell Res Ther. 2022 Jul 15;13(1):297. doi: 10.1186/s13287-022-02986-x. Stem Cell Res Ther. 2022. PMID: 35841017 Free PMC article.
CONCLUSION: Collectively, lncRNA TUG1 carried by USC-Exo regulated ASCL4-mediated ferroptosis by interacting with SRSF1 and then protected IRI-induced AKI. ...
CONCLUSION: Collectively, lncRNA TUG1 carried by USC-Exo regulated ASCL4-mediated ferroptosis by interacting with SRSF1 and then prot …
Acyl-CoA synthase ACSL4: an essential target in ferroptosis and fatty acid metabolism.
Ding K, Liu C, Li L, Yang M, Jiang N, Luo S, Sun L. Ding K, et al. Chin Med J (Engl). 2023 Nov 5;136(21):2521-2537. doi: 10.1097/CM9.0000000000002533. Chin Med J (Engl). 2023. PMID: 37442770 Free PMC article. Review.
In this review, we focus on the structure, biological function, and unique role of ASCL4 in various human diseases. Finally, we propose that ACSL4 might be a potential therapeutic target....
In this review, we focus on the structure, biological function, and unique role of ASCL4 in various human diseases. Finally, we propo …
Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids.
Li YJ, Fahrmann JF, Aftabizadeh M, Zhao Q, Tripathi SC, Zhang C, Yuan Y, Ann D, Hanash S, Yu H. Li YJ, et al. Cell Rep. 2022 May 31;39(9):110870. doi: 10.1016/j.celrep.2022.110870. Cell Rep. 2022. PMID: 35649368 Free article.
Conversely, in both cultured tumor cells and xenograft tumors, enhanced cancer cell apoptosis by inhibiting ASCL4 or specifically targeting acetylated-STAT3 is associated with a reduction in phospholipids within mitochondrial membranes. ...
Conversely, in both cultured tumor cells and xenograft tumors, enhanced cancer cell apoptosis by inhibiting ASCL4 or specifically tar …
Lapatinib induces mitochondrial dysfunction to enhance oxidative stress and ferroptosis in doxorubicin-induced cardiomyocytes via inhibition of PI3K/AKT signaling pathway.
Sun L, Wang H, Xu D, Yu S, Zhang L, Li X. Sun L, et al. Bioengineered. 2022 Jan;13(1):48-60. doi: 10.1080/21655979.2021.2004980. Bioengineered. 2022. PMID: 34898356 Free PMC article.
Moreover, the activity of ROS, SOD, CAT and GSH were measured to elucidate oxidative stress level. Ferroptosis was examined by levels of Fe(2+), GPX4 and ASCL4. Expressions of PI3K/AKT signaling were identified by western blot assay. ...
Moreover, the activity of ROS, SOD, CAT and GSH were measured to elucidate oxidative stress level. Ferroptosis was examined by levels of Fe( …
Downregulation of circular RNA 00091761 protects against heart failure after myocardial infarction via microRNA-335-3p/ ASCL4 axis.
Wei Q, Jiang M, Tang B, You L, Zhao L. Wei Q, et al. Acta Biochim Pol. 2023 Sep 6;70(3):509-516. doi: 10.18388/abp.2020_6404. Acta Biochim Pol. 2023. PMID: 37672718 Free article.
Luciferase reporter as well as RNA pull-down assays revealed the binding relationship between miR-335-3p and circ_0091761 or ASCL4. Circ_0091761 was upregulated in H/R injured H9c2 cells. Knockdown of circ_0091761 promoted cell proliferation and suppressed ferroptosis of H …
Luciferase reporter as well as RNA pull-down assays revealed the binding relationship between miR-335-3p and circ_0091761 or ASCL4. C …
ACSL4 is essential for radiation-induced intestinal injury by initiating ferroptosis.
Ji Q, Fu S, Zuo H, Huang Y, Chu L, Zhu Y, Hu J, Wu Y, Chen S, Wang Y, Ren Y, Pu X, Liu N, Li R, Wang X, Dai C. Ji Q, et al. Cell Death Discov. 2022 Jul 22;8(1):332. doi: 10.1038/s41420-022-01127-w. Cell Death Discov. 2022. PMID: 35869042 Free PMC article.
Antibacterial and antifungal regents reduced the expression of ASCL4 and protected against tissue injury in irradiated intestine tissues. ...
Antibacterial and antifungal regents reduced the expression of ASCL4 and protected against tissue injury in irradiated intestine tiss …
Acyl-CoA synthetase-4 mediates radioresistance of breast cancer cells by regulating FOXM1.
Kwon YS, Lee MG, Baek J, Kim NY, Jang H, Kim S. Kwon YS, et al. Biochem Pharmacol. 2021 Oct;192:114718. doi: 10.1016/j.bcp.2021.114718. Epub 2021 Aug 3. Biochem Pharmacol. 2021. PMID: 34358518
Targeting ACSL4 improved response to irradiation and inhibited migration activities. Furthermore, inhibition of ACLS4 using ASCL4 siRNA or triacsin C suppressed FOXM1 expression, whereas inhibition of FOXM1 using thiostrepton did not affect ACSL4 expression. Targeting the …
Targeting ACSL4 improved response to irradiation and inhibited migration activities. Furthermore, inhibition of ACLS4 using ASCL4 siR …
APOBEC-1 deletion enhances cisplatin-induced acute kidney injury.
Guo X, Blanc V, Davidson NO, Velazquez H, Chen TM, Moledina DG, Moeckel GW, Safirstein RL, Desir GV. Guo X, et al. Sci Rep. 2023 Dec 14;13(1):22255. doi: 10.1038/s41598-023-49575-3. Sci Rep. 2023. PMID: 38097707 Free PMC article.
The kidneys of Apobec-1 KO mice showed increased necrosis, increased expression of KIM-1, NGAL, RIPK1, ASCL4 and increased lipid accumulation compared to WT kidneys (p < 0.01). ...
The kidneys of Apobec-1 KO mice showed increased necrosis, increased expression of KIM-1, NGAL, RIPK1, ASCL4 and increased lipid accu …
Tetrachloro- and tetrabromoarsonium(V) cations: raman and 75As, 19F NMR spectroscopic characterization and X-ray crystal structures of [AsCl4][As(OTeF5)6] and [AsBr4][AsF(OTeF5)5] .
Gerken M, Kolb P, Wegner A, Mercier HP, Borrmann H, Dixon DA, Schrobilgen GJ. Gerken M, et al. Inorg Chem. 2000 Jun 26;39(13):2813-24. doi: 10.1021/ic000118g. Inorg Chem. 2000. PMID: 11232818
The salts [AsX4][As(OTeF5)6] and [AsBr4][AsF(OTeF5)5] (X = Cl, Br) have been prepared by oxidation of AsX3 with XOTeF5 in the presence of the OTeF5 acceptors As(OTeF5)5 and AsF(OTeF5)4. The mixed salts [AsCl4][Sb(OTeF5)6-nCl(n-2)] and [AsCl4][Sb(OTeF5)6-nCl(n)] (n & …
The salts [AsX4][As(OTeF5)6] and [AsBr4][AsF(OTeF5)5] (X = Cl, Br) have been prepared by oxidation of AsX3 with XOTeF5 in the presence of th …
Mitochondrial Inhibitor Rotenone Triggers and Enhances Neuronal Ferroptosis Following Intracerebral Hemorrhage.
Cheng Y, Zhang Z, Tang H, Chen B, Cai Y, Wei Y, Zhao W, Wu ZB, Shang H. Cheng Y, et al. ACS Chem Neurosci. 2023 Mar 15;14(6):1071-1079. doi: 10.1021/acschemneuro.2c00308. Epub 2023 Feb 27. ACS Chem Neurosci. 2023. PMID: 36848438
Single Rot administration markedly inhibited neuronal viability, promoted iron accumulation, increased malondialdehyde (MDA) contents, decreased total superoxide dismutase (SOD) activity, and downregulated ferroptosis-related proteins RPL8, COX-2, xCT, ASCL4, and GPX4 in p …
Single Rot administration markedly inhibited neuronal viability, promoted iron accumulation, increased malondialdehyde (MDA) contents, decre …
32 results