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Items: 1 to 50 of 626

1.

Acute manganese treatment restores defective autophagic cargo loading in Huntington's Disease cell lines.

Bryan MR, O'Brien MT, Nordham KD, Rose DIR, Foshage AM, Joshi P, Nitin R, Uhouse MA, Di Pardo A, Zhang Z, Maglione V, Aschner M, Bowman AB.

Hum Mol Genet. 2019 Oct 10. pii: ddz209. doi: 10.1093/hmg/ddz209. [Epub ahead of print]

PMID:
31600787
2.

Role of Astrocytes in Manganese Neurotoxicity Revisited.

Ke T, Sidoryk-Wegrzynowicz M, Pajarillo E, Rizor A, Soares FAA, Lee E, Aschner M.

Neurochem Res. 2019 Sep 30. doi: 10.1007/s11064-019-02881-7. [Epub ahead of print] Review.

PMID:
31571097
3.

Molecular Docking of Isolated Alkaloids for Possible α-Glucosidase Inhibition.

Rahman N, Muhammad I; Gul-E-Nayab, Khan H, Aschner M, Filosa R, Daglia M.

Biomolecules. 2019 Sep 27;9(10). pii: E544. doi: 10.3390/biom9100544.

4.

New Insights on the Role of Manganese in Alzheimer's Disease and Parkinson's Disease.

Martins AC Jr, Morcillo P, Ijomone OM, Venkataramani V, Harrison FE, Lee E, Bowman AB, Aschner M.

Int J Environ Res Public Health. 2019 Sep 22;16(19). pii: E3546. doi: 10.3390/ijerph16193546. Review.

5.

The role of poly(ADP-ribose) polymerases in manganese exposed Caenorhabditis elegans.

Neumann C, Baesler J, Steffen G, Nicolai MM, Zubel T, Aschner M, Bürkle A, Mangerich A, Schwerdtle T, Bornhorst J.

J Trace Elem Med Biol. 2019 Sep 14;57:21-27. doi: 10.1016/j.jtemb.2019.09.001. [Epub ahead of print]

PMID:
31546209
6.

Huntington's disease associated resistance to Mn neurotoxicity is neurodevelopmental stage and neuronal lineage dependent.

Joshi P, Bodnya C, Ilieva I, Neely MD, Aschner M, Bowman AB.

Neurotoxicology. 2019 Sep 20;75:148-157. doi: 10.1016/j.neuro.2019.09.007. [Epub ahead of print]

PMID:
31545971
7.

Bacteria affect Caenorhabditis elegans responses to MeHg toxicity.

Ke T, Aschner M.

Neurotoxicology. 2019 Sep 19;75:129-135. doi: 10.1016/j.neuro.2019.09.002. [Epub ahead of print]

PMID:
31542475
8.

Role for calcium signaling in manganese neurotoxicity.

Ijomone OM, Aluko OM, Okoh COA, Martins AC Jr, Aschner M.

J Trace Elem Med Biol. 2019 Dec;56:146-155. doi: 10.1016/j.jtemb.2019.08.006. Epub 2019 Aug 22. Review.

PMID:
31470248
9.

Aluminium levels in hair and urine are associated with overweight and obesity in a non-occupationally exposed population.

Tinkov AA, Skalnaya MG, Aaseth J, Ajsuvakova OP, Aschner M, Skalny AV.

J Trace Elem Med Biol. 2019 Dec;56:139-145. doi: 10.1016/j.jtemb.2019.08.005. Epub 2019 Aug 17.

PMID:
31470247
10.

Lead (Pb) exposure induces dopaminergic neurotoxicity in Caenorhabditis elegans: Involvement of the dopamine transporter.

Akinyemi AJ, Miah MR, Ijomone OM, Tsatsakis A, Soares FAA, Tinkov AA, Skalny AV, Venkataramani V, Aschner M.

Toxicol Rep. 2019 Aug 11;6:833-840. doi: 10.1016/j.toxrep.2019.08.001. eCollection 2019.

11.

Blood reference values for metals in a general adult population in southern Brazil.

Almeida Lopes ACB, Cunha AMD, Urbano MR, Buzzo ML, Camargo AEI, Peixe TS, Aschner M, Barbosa F, da Silva AMR, Paoliello MMB.

Environ Res. 2019 Oct;177:108646. doi: 10.1016/j.envres.2019.108646. Epub 2019 Aug 10. No abstract available.

PMID:
31446091
12.

Brain diseases in changing climate.

Ruszkiewicz JA, Tinkov AA, Skalny AV, Siokas V, Dardiotis E, Tsatsakis A, Bowman AB, da Rocha JBT, Aschner M.

Environ Res. 2019 Oct;177:108637. doi: 10.1016/j.envres.2019.108637. Epub 2019 Aug 8. Review.

PMID:
31416010
13.

The biochemistry of mercury toxicity.

Aschner M, Carvalho C.

Biochim Biophys Acta Gen Subj. 2019 Aug 8:129412. doi: 10.1016/j.bbagen.2019.129412. [Epub ahead of print] No abstract available.

PMID:
31401179
14.

Triclosan induces PC12 cells injury is accompanied by inhibition of AKT/mTOR and activation of p38 pathway.

Li SJ, Chen P, Peres TV, Villahoz BF, Zhang Z, Miah MR, Aschner M.

Neurotoxicology. 2019 Sep;74:221-229. doi: 10.1016/j.neuro.2019.07.008. Epub 2019 Aug 2.

PMID:
31381933
15.

Astrocytic Oxidative/Nitrosative Stress Contributes to Parkinson's Disease Pathogenesis: The Dual Role of Reactive Astrocytes.

Rizor A, Pajarillo E, Johnson J, Aschner M, Lee E.

Antioxidants (Basel). 2019 Aug 1;8(8). pii: E265. doi: 10.3390/antiox8080265. Review.

16.

Nrf2-regulated miR-380-3p blocks the translation of Sp3 protein and its mediation of paraquat-induced toxicity in mouse neuroblastoma N2a cells.

Cai Z, Zheng F, Ding Y, Zhan Y, Gong R, Li J, Aschner M, Zhang Q, Wu S, Li H.

Toxicol Sci. 2019 Jul 31. pii: kfz162. doi: 10.1093/toxsci/kfz162. [Epub ahead of print]

17.

Natural Products in the Promotion of Healthspan and Longevity.

Niso-Santano M, González-Polo RA, Paredes-Barquero M, Fuentes JM, Aschner M.

Clin Pharmacol Transl Med. 2019;3(1):149-151. doi: 10.31700/2572-7656.000123. Epub 2019 Jul 16. No abstract available.

18.

Selenoneine ameliorates peroxide-induced oxidative stress in C. elegans.

Rohn I, Kroepfl N, Aschner M, Bornhorst J, Kuehnelt D, Schwerdtle T.

J Trace Elem Med Biol. 2019 Sep;55:78-81. doi: 10.1016/j.jtemb.2019.05.012. Epub 2019 May 31.

PMID:
31345370
19.

Zn homeostasis in genetic models of Parkinson's disease in Caenorhabditis elegans.

Baesler J, Kopp JF, Pohl G, Aschner M, Haase H, Schwerdtle T, Bornhorst J.

J Trace Elem Med Biol. 2019 Sep;55:44-49. doi: 10.1016/j.jtemb.2019.05.005. Epub 2019 May 29.

20.

Curcumin protects against methylmercury-induced cytotoxicity in primary rat astrocytes by activating the Nrf2/ARE pathway independently of PKCδ.

Yang B, Yin C, Zhou Y, Wang Q, Jiang Y, Bai Y, Qian H, Xing G, Wang S, Li F, Feng Y, Zhang Y, Cai J, Aschner M, Lu R.

Toxicology. 2019 Sep 1;425:152248. doi: 10.1016/j.tox.2019.152248. Epub 2019 Jul 19.

PMID:
31330227
21.

MALAT1 rs664589 polymorphism inhibits binding to miR-194-5p contributing to colorectal cancer risk, growth and metastasis.

Wu S, Sun H, Wang Y, Yang X, Meng Q, Yang H, Zhu H, Tang W, Li X, Aschner M, Chen R.

Cancer Res. 2019 Jul 16. pii: canres.0773.2019. doi: 10.1158/0008-5472.CAN-19-0773. [Epub ahead of print]

PMID:
31311811
22.

The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.

Chen S, Li D, Zhang H, Yu D, Chen R, Zhang B, Tan Y, Niu Y, Duan H, Mai B, Chen S, Yu J, Luan T, Chen L, Xing X, Li Q, Xiao Y, Dong G, Niu Y, Aschner M, Zhang R, Zheng Y, Chen W.

Environ Int. 2019 Oct;131:104943. doi: 10.1016/j.envint.2019.104943. Epub 2019 Jul 8.

23.

Caenorhabditis elegans as a tool for environmental risk assessment: emerging and promising applications for a "nobelized worm".

Queirós L, Pereira JL, Gonçalves FJM, Pacheco M, Aschner M, Pereira P.

Crit Rev Toxicol. 2019 Jul 3:1-19. doi: 10.1080/10408444.2019.1626801. [Epub ahead of print]

PMID:
31268799
24.

Therapeutic potential of naringin in neurological disorders.

Ahmed S, Khan H, Aschner M, Hasan MM, Hassan STS.

Food Chem Toxicol. 2019 Oct;132:110646. doi: 10.1016/j.fct.2019.110646. Epub 2019 Jun 26. Review.

PMID:
31252025
25.

Caenorhabditis elegans and its applicability to studies on restless legs syndrome.

Chen P, Ijomone OM, Lee KH, Aschner M.

Adv Pharmacol. 2019;84:147-174. doi: 10.1016/bs.apha.2018.12.003. Epub 2019 Mar 14.

26.

Type 2 diabetes induced oxidative brain injury involves altered cerebellar neuronal integrity and elemental distribution, and exacerbated Nrf2 expression: therapeutic potential of raffia palm (Raphia hookeri) wine.

Erukainure OL, Ijomone OM, Sanni O, Aschner M, Islam MS.

Metab Brain Dis. 2019 Oct;34(5):1385-1399. doi: 10.1007/s11011-019-00444-x. Epub 2019 Jun 14.

PMID:
31201727
27.

Colonic Injuries Induced by Inhalational Exposure to Particulate-Matter Air Pollution.

Li X, Cui J, Yang H, Sun H, Lu R, Gao N, Meng Q, Wu S, Wu J, Aschner M, Chen R.

Adv Sci (Weinh). 2019 Apr 9;6(11):1900180. doi: 10.1002/advs.201900180. eCollection 2019 Jun 5.

28.

Mercury in Our Food.

Nogara PA, Farina M, Aschner M, Rocha JBT.

Chem Res Toxicol. 2019 Aug 19;32(8):1459-1461. doi: 10.1021/acs.chemrestox.9b00126. Epub 2019 May 24.

PMID:
31124669
29.

Smoking and DNA methylation: Correlation of methylation with smoking behavior and association with diseases and fetus development following prenatal exposure.

Fragou D, Pakkidi E, Aschner M, Samanidou V, Kovatsi L.

Food Chem Toxicol. 2019 Jul;129:312-327. doi: 10.1016/j.fct.2019.04.059. Epub 2019 May 4. Review.

PMID:
31063835
30.

Polyphenols in the treatment of autoimmune diseases.

Khan H, Sureda A, Belwal T, Çetinkaya S, Süntar İ, Tejada S, Devkota HP, Ullah H, Aschner M.

Autoimmun Rev. 2019 Jul;18(7):647-657. doi: 10.1016/j.autrev.2019.05.001. Epub 2019 May 3. Review.

PMID:
31059841
31.

Hyperglycemia-induced oxidative brain injury: Therapeutic effects of Cola nitida infusion against redox imbalance, cerebellar neuronal insults, and upregulated Nrf2 expression in type 2 diabetic rats.

Erukainure OL, Ijomone OM, Oyebode OA, Chukwuma CI, Aschner M, Islam MS.

Food Chem Toxicol. 2019 May;127:206-217. doi: 10.1016/j.fct.2019.03.044. Epub 2019 Mar 23.

PMID:
30914353
32.

Editorial: Sex and Gene-Dependent Neurotoxicity.

Ruszkiewicz JA, Aschner M.

Front Genet. 2019 Mar 5;10:165. doi: 10.3389/fgene.2019.00165. eCollection 2019. No abstract available.

33.

Multiple organ injury in male C57BL/6J mice exposed to ambient particulate matter in a real-ambient PM exposure system in Shijiazhuang, China.

Li D, Zhang R, Cui L, Chu C, Zhang H, Sun H, Luo J, Zhou L, Chen L, Cui J, Chen S, Mai B, Chen S, Yu J, Cai Z, Zhang J, Jiang Y, Aschner M, Chen R, Zheng Y, Chen W.

Environ Pollut. 2019 May;248:874-887. doi: 10.1016/j.envpol.2019.02.097. Epub 2019 Mar 2.

PMID:
30856503
34.

Manganese: Its Role in Disease and Health.

Erikson KM, Aschner M.

Met Ions Life Sci. 2019 Jan 14;19. pii: /books/9783110527872/9783110527872-016/9783110527872-016.xml. doi: 10.1515/9783110527872-016. Review.

PMID:
30855111
35.

The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics.

Pajarillo E, Rizor A, Lee J, Aschner M, Lee E.

Neuropharmacology. 2019 Mar 6. pii: S0028-3908(19)30080-2. doi: 10.1016/j.neuropharm.2019.03.002. [Epub ahead of print] Review.

PMID:
30851309
36.

Comparison of the neurotoxicity associated with cobalt nanoparticles and cobalt chloride in Wistar rats.

Zheng F, Luo Z, Zheng C, Li J, Zeng J, Yang H, Chen J, Jin Y, Aschner M, Wu S, Zhang Q, Li H.

Toxicol Appl Pharmacol. 2019 Apr 15;369:90-99. doi: 10.1016/j.taap.2019.03.003. Epub 2019 Mar 5.

PMID:
30849457
37.

Plant components can reduce methylmercury toxication: A mini-review.

Chang J, Zhou Y, Wang Q, Aschner M, Lu R.

Biochim Biophys Acta Gen Subj. 2019 Mar 6:129290. doi: 10.1016/j.bbagen.2019.01.012. [Epub ahead of print] Review.

PMID:
30849424
38.

Treatment of Caenorhabditis elegans with Small Selenium Species Enhances Antioxidant Defense Systems.

Rohn I, Raschke S, Aschner M, Tuck S, Kuehnelt D, Kipp A, Schwerdtle T, Bornhorst J.

Mol Nutr Food Res. 2019 May;63(9):e1801304. doi: 10.1002/mnfr.201801304. Epub 2019 Mar 13.

PMID:
30815971
39.

Iron and manganese-related CNS toxicity: mechanisms, diagnosis and treatment.

Chen P, Totten M, Zhang Z, Bucinca H, Erikson K, Santamaría A, Bowman AB, Aschner M.

Expert Rev Neurother. 2019 Mar;19(3):243-260. doi: 10.1080/14737175.2019.1581608. Epub 2019 Feb 21.

PMID:
30759034
40.

Human-induced pluripotent stems cells as a model to dissect the selective neurotoxicity of methylmercury.

Prince LM, Aschner M, Bowman AB.

Biochim Biophys Acta Gen Subj. 2019 Feb 10:129300. doi: 10.1016/j.bbagen.2019.02.002. [Epub ahead of print] Review.

PMID:
30742955
41.

Acute glufosinate-based herbicide treatment in rats leads to increased ocular interleukin-1β and c-Fos protein levels, as well as intraocular pressure.

Çomaklı S, Sevim Ç, Kontadakis G, Doğan E, Taghizadehghalehjoughi A, Özkaraca M, Aschner M, Nikolouzakis TK, Tsatsakis A.

Toxicol Rep. 2019 Jan 16;6:155-160. doi: 10.1016/j.toxrep.2019.01.004. eCollection 2019.

42.

Assessment of occupational exposures to multiple metals with urinary porphyrin profiles.

de Andrade VL, Mateus ML, Aschner M, Dos Santos AM.

J Integr OMICS. 2018 Jun;8(1). pii: 216. doi: 10.5584/jiomics.v8i1.216. Epub 2018 Apr 16.

43.

Methylmercury's chemistry: From the environment to the mammalian brain.

Nogara PA, Oliveira CS, Schmitz GL, Piquini PC, Farina M, Aschner M, Rocha JBT.

Biochim Biophys Acta Gen Subj. 2019 Jan 17:129284. doi: 10.1016/j.bbagen.2019.01.006. [Epub ahead of print] Review.

PMID:
30659885
44.

Glutathione antioxidant system and methylmercury-induced neurotoxicity: An intriguing interplay.

Farina M, Aschner M.

Biochim Biophys Acta Gen Subj. 2019 Jan 16:129285. doi: 10.1016/j.bbagen.2019.01.007. [Epub ahead of print] Review.

PMID:
30659883
45.

LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia.

Kim J, Pajarillo E, Rizor A, Son DS, Lee J, Aschner M, Lee E.

PLoS One. 2019 Jan 15;14(1):e0210248. doi: 10.1371/journal.pone.0210248. eCollection 2019.

46.

Editorial.

Aschner M, Autrup HN, Cohen SM, Dekant W, Eisenbrand G, Galli CL, Gori GB, Kaminski NE, Klaassen CD, Klaunig JE, Levy L, Lotti M, Marquardt HW, Pelkonen O, Schrenk DF, Yamazaki H.

Regul Toxicol Pharmacol. 2019 Feb;101:A1-A2. doi: 10.1016/j.yrtph.2018.12.015. No abstract available.

PMID:
30642615
47.

Cancer-associated stroke: Pathophysiology, detection and management (Review).

Dardiotis E, Aloizou AM, Markoula S, Siokas V, Tsarouhas K, Tzanakakis G, Libra M, Kyritsis AP, Brotis AG, Aschner M, Gozes I, Bogdanos DP, Spandidos DA, Mitsias PD, Tsatsakis A.

Int J Oncol. 2019 Mar;54(3):779-796. doi: 10.3892/ijo.2019.4669. Epub 2019 Jan 2. Review.

48.

Sex-Specific Differences in Redox Homeostasis in Brain Norm and Disease.

Ruszkiewicz JA, Miranda-Vizuete A, Tinkov AA, Skalnaya MG, Skalny AV, Tsatsakis A, Aschner M.

J Mol Neurosci. 2019 Feb;67(2):312-342. doi: 10.1007/s12031-018-1241-9. Epub 2019 Jan 2. Review.

PMID:
30604380
49.

Hormetic Neurobehavioral effects of low dose toxic chemical mixtures in real-life risk simulation (RLRS) in rats.

Tsatsakis AM, Docea AO, Calina D, Buga AM, Zlatian O, Gutnikov S, Kostoff RN, Aschner M.

Food Chem Toxicol. 2019 Mar;125:141-149. doi: 10.1016/j.fct.2018.12.043. Epub 2018 Dec 27.

PMID:
30594548
50.

SLC30A10 transporter in the digestive system regulates brain manganese under basal conditions while brain SLC30A10 protects against neurotoxicity.

Taylor CA, Hutchens S, Liu C, Jursa T, Shawlot W, Aschner M, Smith DR, Mukhopadhyay S.

J Biol Chem. 2019 Feb 8;294(6):1860-1876. doi: 10.1074/jbc.RA118.005628. Epub 2018 Dec 17.

PMID:
30559290

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