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Items: 1 to 50 of 61

1.

A double-blind randomized comparative clinical trial to evaluate the safety and efficacy of dendritic cell vaccine loaded with WT1 peptides (TLP0-001) in combination with S-1 in patients with advanced pancreatic cancer refractory to standard chemotherapy.

Katsuda M, Miyazawa M, Ojima T, Katanuma A, Hakamada K, Sudo K, Asahara S, Endo I, Ueno M, Hara K, Yamada S, Fujii T, Satoi S, Ioka T, Ohira M, Akahori T, Kitano M, Nagano H, Furukawa M, Adachi T, Yamaue H.

Trials. 2019 Apr 27;20(1):242. doi: 10.1186/s13063-019-3332-5.

2.

Effects of low-dose combined oral contraceptives and protein S K196E mutation on anticoagulation factors: a prospective observational study.

Miyoshi T, Oku H, Asahara S, Okamoto A, Kokame K, Nakai M, Nishimura K, Otsuka F, Higashiyama A, Yoshimatsu J, Miyata T.

Int J Hematol. 2019 Jun;109(6):641-649. doi: 10.1007/s12185-019-02633-x. Epub 2019 Mar 19.

PMID:
30891674
3.

Effectiveness on high-grade cervical abnormalities and long-term safety of the quadrivalent human papillomavirus vaccine in Japanese women.

Sakamoto M, Miyagi E, Sumi Y, Aisaka K, Kuno N, Nagano H, Asahara S, Han SR, Wakana A, Murata S, Sawata M, Tanaka Y.

J Infect Chemother. 2019 Jul;25(7):520-525. doi: 10.1016/j.jiac.2019.02.012. Epub 2019 Mar 15.

4.

SGLT2 inhibitors and protection against pancreatic beta cell failure.

Asahara SI, Ogawa W.

Diabetol Int. 2018 Sep 17;10(1):1-2. doi: 10.1007/s13340-018-0374-y. eCollection 2019 Jan. No abstract available.

PMID:
30800558
5.

Neuronatin and glucose-induced stress in pancreatic β-cells.

Asahara SI.

J Diabetes Investig. 2019 May;10(3):574-576. doi: 10.1111/jdi.12993. Epub 2019 Jan 23.

6.

Docosahexaenoic Acid Reduces Palmitic Acid-Induced Endoplasmic Reticulum Stress in Pancreatic Β Cells.

Suzuki E, Matsuda T, Kawamoto T, Takahashi H, Mieda Y, Matsuura Y, Takai T, Kanno A, Koyanagi-Kimura M, Asahara SI, Inoue H, Ogawa W, Kido Y.

Kobe J Med Sci. 2018 Sep 11;64(2):E43-E55.

7.

Early administration of dapagliflozin preserves pancreatic β-cell mass through a legacy effect in a mouse model of type 2 diabetes.

Kanno A, Asahara SI, Kawamura M, Furubayashi A, Tsuchiya S, Suzuki E, Takai T, Koyanagi-Kimura M, Matsuda T, Okada Y, Ogawa W, Kido Y.

J Diabetes Investig. 2019 May;10(3):577-590. doi: 10.1111/jdi.12945. Epub 2018 Nov 8.

8.

PHD3 regulates glucose metabolism by suppressing stress-induced signalling and optimising gluconeogenesis and insulin signalling in hepatocytes.

Yano H, Sakai M, Matsukawa T, Yagi T, Naganuma T, Mitsushima M, Iida S, Inaba Y, Inoue H, Unoki-Kubota H, Kaburagi Y, Asahara SI, Kido Y, Minami S, Kasuga M, Matsumoto M.

Sci Rep. 2018 Sep 24;8(1):14290. doi: 10.1038/s41598-018-32575-z.

9.

Casein kinase 2 phosphorylates and stabilizes C/EBPβ in pancreatic β cells.

Takai T, Matsuda T, Matsuura Y, Inoue K, Suzuki E, Kanno A, Kimura-Koyanagi M, Asahara SI, Hatano N, Ogawa W, Kido Y.

Biochem Biophys Res Commun. 2018 Feb 26;497(1):451-456. doi: 10.1016/j.bbrc.2018.02.108. Epub 2018 Feb 12.

PMID:
29448105
10.

MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling.

Bartolomé A, García-Aguilar A, Asahara SI, Kido Y, Guillén C, Pajvani UB, Benito M.

Mol Cell Biol. 2017 Nov 13;37(23). pii: e00441-17. doi: 10.1128/MCB.00441-17. Print 2017 Dec 1.

11.

Histone deacetylase regulates insulin signaling via two pathways in pancreatic β cells.

Kawada Y, Asahara SI, Sugiura Y, Sato A, Furubayashi A, Kawamura M, Bartolome A, Terashi-Suzuki E, Takai T, Kanno A, Koyanagi-Kimura M, Matsuda T, Hashimoto N, Kido Y.

PLoS One. 2017 Sep 8;12(9):e0184435. doi: 10.1371/journal.pone.0184435. eCollection 2017.

12.

An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving 'subsampling' issues.

Ono Y, Sugitani A, Karasaki H, Ogata M, Nozaki R, Sasajima J, Yokochi T, Asahara S, Koizumi K, Ando K, Hironaka K, Daito T, Mizukami Y.

Mol Oncol. 2017 Oct;11(10):1448-1458. doi: 10.1002/1878-0261.12110. Epub 2017 Aug 8.

13.

Antithrombin III for portal vein thrombosis in patients with liver disease: A randomized, double-blind, controlled trial.

Hidaka H, Kokubu S, Sato T, Katsushima S, Izumi N, Igura T, Asahara S, Notsumata K, Osaki Y, Tsuji K, Kawanaka H, Akahoshi T, Hirota S, Matsutani S; NPB-06 study group.

Hepatol Res. 2018 Feb;48(3):E107-E116. doi: 10.1111/hepr.12934. Epub 2017 Aug 7.

PMID:
28666312
14.

Dietary Mung Bean Protein Reduces Hepatic Steatosis, Fibrosis, and Inflammation in Male Mice with Diet-Induced, Nonalcoholic Fatty Liver Disease.

Watanabe H, Inaba Y, Kimura K, Asahara SI, Kido Y, Matsumoto M, Motoyama T, Tachibana N, Kaneko S, Kohno M, Inoue H.

J Nutr. 2017 Jan;147(1):52-60. doi: 10.3945/jn.116.231662. Epub 2016 Nov 30.

PMID:
27903831
15.

Central Insulin Action Activates Kupffer Cells by Suppressing Hepatic Vagal Activation via the Nicotinic Alpha 7 Acetylcholine Receptor.

Kimura K, Tanida M, Nagata N, Inaba Y, Watanabe H, Nagashimada M, Ota T, Asahara S, Kido Y, Matsumoto M, Toshinai K, Nakazato M, Shibamoto T, Kaneko S, Kasuga M, Inoue H.

Cell Rep. 2016 Mar 15;14(10):2362-74. doi: 10.1016/j.celrep.2016.02.032. Epub 2016 Mar 3.

16.

Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c.

Asahara S, Etoh H, Inoue H, Teruyama K, Shibutani Y, Ihara Y, Kawada Y, Bartolome A, Hashimoto N, Matsuda T, Koyanagi-Kimura M, Kanno A, Hirota Y, Hosooka T, Nagashima K, Nishimura W, Inoue H, Matsumoto M, Higgins MJ, Yasuda K, Inagaki N, Seino S, Kasuga M, Kido Y.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8332-7. doi: 10.1073/pnas.1422104112. Epub 2015 Jun 22.

17.

Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity.

Matsuda T, Takahashi H, Mieda Y, Shimizu S, Kawamoto T, Matsuura Y, Takai T, Suzuki E, Kanno A, Koyanagi-Kimura M, Asahara S, Bartolome A, Yokoi N, Inoue H, Ogawa W, Seino S, Kido Y.

PLoS One. 2015 Jun 19;10(6):e0130757. doi: 10.1371/journal.pone.0130757. eCollection 2015.

18.

Compensatory hyperinsulinemia in high-fat diet-induced obese mice is associated with enhanced insulin translation in islets.

Kanno A, Asahara SI, Masuda K, Matsuda T, Kimura-Koyanagi M, Seino S, Ogawa W, Kido Y.

Biochem Biophys Res Commun. 2015 Mar 13;458(3):681-686. doi: 10.1016/j.bbrc.2015.02.024. Epub 2015 Feb 14.

PMID:
25686499
19.

Pancreatic β-cell failure mediated by mTORC1 hyperactivity and autophagic impairment.

Bartolomé A, Kimura-Koyanagi M, Asahara S, Guillén C, Inoue H, Teruyama K, Shimizu S, Kanno A, García-Aguilar A, Koike M, Uchiyama Y, Benito M, Noda T, Kido Y.

Diabetes. 2014 Sep;63(9):2996-3008. doi: 10.2337/db13-0970. Epub 2014 Apr 16.

20.

Phase I/II clinical trial using HLA-A24-restricted peptide vaccine derived from KIF20A for patients with advanced pancreatic cancer.

Asahara S, Takeda K, Yamao K, Maguchi H, Yamaue H.

J Transl Med. 2013 Nov 16;11:291. doi: 10.1186/1479-5876-11-291.

21.
22.

Histidine augments the suppression of hepatic glucose production by central insulin action.

Kimura K, Nakamura Y, Inaba Y, Matsumoto M, Kido Y, Asahara S, Matsuda T, Watanabe H, Maeda A, Inagaki F, Mukai C, Takeda K, Akira S, Ota T, Nakabayashi H, Kaneko S, Kasuga M, Inoue H.

Diabetes. 2013 Jul;62(7):2266-77. doi: 10.2337/db12-1701. Epub 2013 Mar 8.

23.

Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin.

Asahara S, Shibutani Y, Teruyama K, Inoue HY, Kawada Y, Etoh H, Matsuda T, Kimura-Koyanagi M, Hashimoto N, Sakahara M, Fujimoto W, Takahashi H, Ueda S, Hosooka T, Satoh T, Inoue H, Matsumoto M, Aiba A, Kasuga M, Kido Y.

Diabetologia. 2013 May;56(5):1088-97. doi: 10.1007/s00125-013-2849-5. Epub 2013 Feb 15.

24.

Influence of viewing distance and size of tv on visual fatigue and feeling of involvement.

Sakamoto K, Asahara S, Yamashita K, Okada A.

J Hum Ergol (Tokyo). 2012 Dec;41(1-2):17-30.

PMID:
25665195
25.

DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice.

Shimizu S, Hosooka T, Matsuda T, Asahara S, Koyanagi-Kimura M, Kanno A, Bartolome A, Etoh H, Fuchita M, Teruyama K, Takahashi H, Inoue H, Mieda Y, Hashimoto N, Seino S, Kido Y.

J Mol Endocrinol. 2012 Aug 30;49(2):125-35. doi: 10.1530/JME-12-0039. Print 2012 Oct.

PMID:
22822047
26.

Endoplasmic reticulum stress inhibits STAT3-dependent suppression of hepatic gluconeogenesis via dephosphorylation and deacetylation.

Kimura K, Yamada T, Matsumoto M, Kido Y, Hosooka T, Asahara S, Matsuda T, Ota T, Watanabe H, Sai Y, Miyamoto K, Kaneko S, Kasuga M, Inoue H.

Diabetes. 2012 Jan;61(1):61-73. doi: 10.2337/db10-1684. Epub 2011 Nov 28.

27.

Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1.

Koyanagi M, Asahara S, Matsuda T, Hashimoto N, Shigeyama Y, Shibutani Y, Kanno A, Fuchita M, Mikami T, Hosooka T, Inoue H, Matsumoto M, Koike M, Uchiyama Y, Noda T, Seino S, Kasuga M, Kido Y.

PLoS One. 2011;6(8):e23238. doi: 10.1371/journal.pone.0023238. Epub 2011 Aug 19.

28.

Evaluation of the effect of viewing distance on visual fatigue in a home viewing environment.

Sakamoto K, Aoyama S, Asahara S, Yamashita K, Okada A.

J Hum Ergol (Tokyo). 2010 Jun;39(1):1-13.

PMID:
21922786
29.

Effect of intrauterine undernutrition during late gestation on pancreatic beta cell mass.

Inoue T, Kido Y, Asahara S, Matsuda T, Shibutani Y, Koyanagi M, Kasuga M.

Biomed Res. 2009 Dec;30(6):325-30.

30.

Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice.

Matsuda T, Kido Y, Asahara S, Kaisho T, Tanaka T, Hashimoto N, Shigeyama Y, Takeda A, Inoue T, Shibutani Y, Koyanagi M, Hosooka T, Matsumoto M, Inoue H, Uchida T, Koike M, Uchiyama Y, Akira S, Kasuga M.

J Clin Invest. 2010 Jan;120(1):115-26. doi: 10.1172/JCI39721. Epub 2009 Dec 1.

31.

Increased ribosomal biogenesis induces pancreatic beta cell failure in mice model of type 2 diabetes.

Asahara S, Matsuda T, Kido Y, Kasuga M.

Biochem Biophys Res Commun. 2009 Apr 10;381(3):367-71.

PMID:
19309774
32.

[A case of splenic inflammatory pseudotumor].

Fujisaki T, Ikari T, Kamei A, Takano K, Kuraoka K, Hirasawa T, Yoshimoto K, Asahara S.

Nihon Shokakibyo Gakkai Zasshi. 2008 Apr;105(4):572-7. Japanese.

PMID:
18388450
33.

[Transcatheter arterial chemoembolization (TACE) using degradable starch microspheres (DSM) for metastatic liver tumors in patients with gastric cancer].

Hirasawa T, Asahara S, Fujisaki S, Kuraoka K, Takano K, Kamei A, Ikari T.

Nihon Shokakibyo Gakkai Zasshi. 2008 Mar;105(3):367-72. Japanese.

PMID:
18332601
34.

Biphasic response of pancreatic beta-cell mass to ablation of tuberous sclerosis complex 2 in mice.

Shigeyama Y, Kobayashi T, Kido Y, Hashimoto N, Asahara S, Matsuda T, Takeda A, Inoue T, Shibutani Y, Koyanagi M, Uchida T, Inoue M, Hino O, Kasuga M, Noda T.

Mol Cell Biol. 2008 May;28(9):2971-9. doi: 10.1128/MCB.01695-07. Epub 2008 Mar 3.

35.

Comparison of low back joint moment using a dynamic 3D biomechanical model in different transferring tasks wearing low back belt.

Katsuhira J, Sasaki H, Asahara S, Ikegami T, Ishihara H, Kikuchi T, Hirai Y, Yamasaki Y, Wada T, Maruyama H.

Gait Posture. 2008 Aug;28(2):258-64. doi: 10.1016/j.gaitpost.2007.12.070. Epub 2008 Feb 15.

PMID:
18280736
36.

[Transcatheter arterial chemoembolization (TACE) using degradable starch microspheres (DSM) (DSM-TACE) for primary and metastatic liver neuroendocrine tumors from gastrointestinal neuroendocrine tumors].

Fujisaki T, Ikari T, Kamei A, Takano K, Kuraoka K, Yoshimoto K, Hirasawa T, Asahara S.

Nihon Shokakibyo Gakkai Zasshi. 2008 Feb;105(2):206-13. Japanese.

PMID:
18250591
37.

Locally advanced intrahepatic cholangiocarcinoma successfully resected after transcatheter arterial chemoembolization with degradable starch microspheres: report of a case.

Wu Y, Saiura A, Yamamoto J, Koga R, Asahara S, Kamei A, Takano K, Ikari T, Seki M, Yamaguchi T, Muto T.

Hepatogastroenterology. 2007 Jul-Aug;54(77):1345-7.

PMID:
17708251
38.

CT and MRI findings with contrast enhancement of small pancreatic adenocarcinoma in the late phase.

Hijioka S, Ikari T, Kamei A, Takano K, Asahara S, Fujita N, Shimizu M, Yamamoto J, Fujita R, Sasaki K.

Hepatogastroenterology. 2007 Mar;54(74):389-92.

PMID:
17523281
39.

Transcatheter arterial chemoembolization with DSM for primary hepatic malignant carcinoid.

Hijioka S, Ikari T, Kamei A, Takano K, Asahara S, Fujita N, Shimizu M, Kuraoka K, Fijita R, Kanda H, Kato Y.

Hepatogastroenterology. 2007 Mar;54(74):382-5.

PMID:
17523279
40.

Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass.

Hashimoto N, Kido Y, Uchida T, Asahara S, Shigeyama Y, Matsuda T, Takeda A, Tsuchihashi D, Nishizawa A, Ogawa W, Fujimoto Y, Okamura H, Arden KC, Herrera PL, Noda T, Kasuga M.

Nat Genet. 2006 May;38(5):589-93. Epub 2006 Apr 23.

PMID:
16642023
41.

[US - IDUS - EUS for diagnosis of biliary tract neoplasms].

Hijioka S, Ikari T, Kamei A, Takano K, Asahara S, Fujita R.

Nihon Rinsho. 2006 Jan;64 Suppl 1:393-7. Review. Japanese. No abstract available.

PMID:
16457290
42.

[A case of diffuse type of hepatocellular carcinoma with tumor thrombosis of inferior vena cava (Vv3) and main trunk of portal vein (Vp4), showing marked response to transcatheter arterial chemoembolization with degradable starch microspheres (DSM-TACE)].

Asahara S, Ikari T, Kamei A, Sato E, Takano K, Fujita N, Shimizu M, Fujita R.

Nihon Shokakibyo Gakkai Zasshi. 2004 Dec;101(12):1332-9. Japanese. No abstract available.

PMID:
15651397
43.
44.

Dermatomyositis and myelodysplastic syndrome with myelofibrosis responding to methotrexate therapy.

Tsuji G, Maekawa S, Saigo K, Nobuhara Y, Nakamura T, Kawano S, Koshiba M, Asahara S, Chinzei T, Kumagai S.

Am J Hematol. 2003 Nov;74(3):175-8.

45.
46.

Strategies for surgical treatment of gallbladder carcinoma based on information available before resection.

Kokudo N, Makuuchi M, Natori T, Sakamoto Y, Yamamoto J, Seki M, Noie T, Sugawara Y, Imamura H, Asahara S, Ikari T.

Arch Surg. 2003 Jul;138(7):741-50; discussion 750.

PMID:
12860755
47.

Effect of intravenous infusion of NIK-716 in anesthetized pediatric patients.

Miyasaka K, Kondo Y, Asahara S, Tamura T, Suzuki Y.

Methods Find Exp Clin Pharmacol. 2002 Dec;24(10):697-701.

PMID:
12616964
48.

Acute lymphoblastic leukemia accompanied by chromosomal abnormality of translocation (12;17).

Asahara SI, Saigo K, Hasuike N, Tamura M, Maeda Y, Tomofuji Y, Chinzei T, Tatsumi E.

Haematologia (Budap). 2001;31(3):209-13. Review.

PMID:
11855782
49.

Analysis of stiffness and stress in I-bar clasps.

Sato Y, Tsuga K, Abe Y, Asahara S, Akagawa Y.

J Oral Rehabil. 2001 Jun;28(6):596-600.

PMID:
11422688
50.

Finite element analysis on preferable I-bar clasp shape.

Sato Y, Tsuga K, Abe Y, Asahara S, Akagawa Y.

J Oral Rehabil. 2001 May;28(5):413-7.

PMID:
11380780

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