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Items: 1 to 50 of 267

1.

Forced isoform switching of Neat1_1 to Neat1_2 leads to the loss of Neat1_1 and the hyperformation of paraspeckles but does not affect the development and growth of mice.

Isobe M, Toya H, Mito M, Chiba T, Asahara H, Hirose T, Nakagawa S.

RNA. 2019 Dec 10. pii: rna.072587.119. doi: 10.1261/rna.072587.119. [Epub ahead of print]

2.

The long noncoding RNA NEAT1_1 is seemingly dispensable for normal tissue homeostasis and cancer cell growth.

Adriaens C, Rambow F, Bervoets G, Silla T, Mito M, Chiba T, Asahara H, Hirose T, Nakagawa S, Jensen TH, Marine JC.

RNA. 2019 Dec;25(12):1681-1695. doi: 10.1261/rna.071456.119. Epub 2019 Sep 24.

PMID:
31551298
3.

Post-transcriptional regulation of inflammation by RNA-binding proteins via cis-elements of mRNAs.

Uchida Y, Chiba T, Kurimoto R, Asahara H.

J Biochem. 2019 Nov 1;166(5):375-382. doi: 10.1093/jb/mvz067. Review.

PMID:
31511872
4.

Comparative analysis demonstrates cell type-specific conservation of SOX9 targets between mouse and chicken.

Yamashita S, Kataoka K, Yamamoto H, Kato T, Hara S, Yamaguchi K, Renard-Guillet C, Katou Y, Shirahige K, Ochi H, Ogino H, Uchida T, Inui M, Takada S, Shigenobu S, Asahara H.

Sci Rep. 2019 Aug 29;9(1):12560. doi: 10.1038/s41598-019-48979-4.

5.

Efficient full spin-orbit torque switching in a single layer of a perpendicularly magnetized single-crystalline ferromagnet.

Jiang M, Asahara H, Sato S, Kanaki T, Yamasaki H, Ohya S, Tanaka M.

Nat Commun. 2019 Jun 13;10(1):2590. doi: 10.1038/s41467-019-10553-x.

6.

Wwp2 maintains cartilage homeostasis through regulation of Adamts5.

Mokuda S, Nakamichi R, Matsuzaki T, Ito Y, Sato T, Miyata K, Inui M, Olmer M, Sugiyama E, Lotz M, Asahara H.

Nat Commun. 2019 Jun 3;10(1):2429. doi: 10.1038/s41467-019-10177-1.

7.

Photochemical C-H oxygenation of side-chain methyl groups in polypropylene with chlorine dioxide.

Ohkubo K, Asahara H, Inoue T.

Chem Commun (Camb). 2019 Apr 16;55(32):4723-4726. doi: 10.1039/c9cc01037h.

PMID:
30942239
8.

Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism.

Sasako T, Ohsugi M, Kubota N, Itoh S, Okazaki Y, Terai A, Kubota T, Yamashita S, Nakatsukasa K, Kamura T, Iwayama K, Tokuyama K, Kiyonari H, Furuta Y, Shibahara J, Fukayama M, Enooku K, Okushin K, Tsutsumi T, Tateishi R, Tobe K, Asahara H, Koike K, Kadowaki T, Ueki K.

Nat Commun. 2019 Feb 27;10(1):947. doi: 10.1038/s41467-019-08591-6.

9.

Zfp238 Regulates the Thermogenic Program in Cooperation with Foxo1.

Kita M, Nakae J, Kawano Y, Asahara H, Takemori H, Okado H, Itoh H.

iScience. 2019 Feb 22;12:87-101. doi: 10.1016/j.isci.2019.01.005. Epub 2019 Jan 7.

10.

Ablation of miR-146b in mice causes hematopoietic malignancy.

Mitsumura T, Ito Y, Chiba T, Matsushima T, Kurimoto R, Tanaka Y, Kato T, Uchida K, Ito T, Yamamoto K, Eishi Y, Kitagawa M, Miyazaki Y, Inase N, Asahara H.

Blood Adv. 2018 Dec 11;2(23):3483-3491. doi: 10.1182/bloodadvances.2018017954.

11.

Alkynylation and Cyanation of Alkenes Using Diverse Properties of a Nitro Group.

Asahara H, Sofue A, Kuroda Y, Nishiwaki N.

J Org Chem. 2018 Nov 16;83(22):13691-13699. doi: 10.1021/acs.joc.8b01865. Epub 2018 Nov 1.

PMID:
30359520
12.

Combinatorial CRISPR/Cas9 Approach to Elucidate a Far-Upstream Enhancer Complex for Tissue-Specific Sox9 Expression.

Mochizuki Y, Chiba T, Kataoka K, Yamashita S, Sato T, Kato T, Takahashi K, Miyamoto T, Kitazawa M, Hatta T, Natsume T, Takai S, Asahara H.

Dev Cell. 2018 Sep 24;46(6):794-806.e6. doi: 10.1016/j.devcel.2018.07.024. Epub 2018 Aug 23.

13.

FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration.

Alvarez-Garcia O, Matsuzaki T, Olmer M, Miyata K, Mokuda S, Sakai D, Masuda K, Asahara H, Lotz MK.

Aging Cell. 2018 Oct;17(5):e12800. doi: 10.1111/acel.12800. Epub 2018 Jul 2.

14.

A tandem repeat array in IG-DMR is essential for imprinting of paternal allele at the Dlk1-Dio3 domain during embryonic development.

Saito T, Hara S, Kato T, Tamano M, Muramatsu A, Asahara H, Takada S.

Hum Mol Genet. 2018 Sep 15;27(18):3283-3292. doi: 10.1093/hmg/ddy235.

PMID:
29931170
15.

[Cartilage/chondrocyte research and osteoarthritis. Current topics and future of ligament regeneration therapy.]

Nakamichi R, Kataoka K, Asahara H.

Clin Calcium. 2018;28(6):809-816. doi: CliCa1806809816. Japanese.

PMID:
29848827
16.

Phosphine Induced Dimerization of Propargyl Alcohols Leading to Allyl Propargyl Ethers.

Iwai K, Yokoyama S, Asahara H, Nishiwaki N.

J Oleo Sci. 2018 Jun 1;67(6):773-778. doi: 10.5650/jos.ess17277. Epub 2018 May 15.

17.

Dissecting the roles of miR-140 and its host gene.

Inui M, Mokuda S, Sato T, Tamano M, Takada S, Asahara H.

Nat Cell Biol. 2018 May;20(5):516-518. doi: 10.1038/s41556-018-0077-4. No abstract available.

18.

Essential role of Mohawk for tenogenic tissue homeostasis including spinal disc and periodontal ligament.

Nakamichi R, Kataoka K, Asahara H.

Mod Rheumatol. 2018 Nov;28(6):933-940. doi: 10.1080/14397595.2018.1466644. Epub 2018 May 15. Review.

19.

FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis.

Matsuzaki T, Alvarez-Garcia O, Mokuda S, Nagira K, Olmer M, Gamini R, Miyata K, Akasaki Y, Su AI, Asahara H, Lotz MK.

Sci Transl Med. 2018 Feb 14;10(428). pii: eaan0746. doi: 10.1126/scitranslmed.aan0746.

20.

Direct Aziridination of Nitroalkenes Affording N-Alkyl-C-nitroaziridines and the Subsequent Lewis Acid Mediated Isomerization to β-Nitroenamines.

Hao F, Asahara H, Nishiwaki N.

Org Lett. 2017 Oct 6;19(19):5442-5445. doi: 10.1021/acs.orglett.7b02724. Epub 2017 Sep 21.

PMID:
28933166
21.

Quantification and Theoretical Analysis of the Electrophilicities of Michael Acceptors.

Allgäuer DS, Jangra H, Asahara H, Li Z, Chen Q, Zipse H, Ofial AR, Mayr H.

J Am Chem Soc. 2017 Sep 27;139(38):13318-13329. doi: 10.1021/jacs.7b05106. Epub 2017 Sep 18.

PMID:
28921959
22.

Development of new experimental platform 'MARS'-Multiple Artificial-gravity Research System-to elucidate the impacts of micro/partial gravity on mice.

Shiba D, Mizuno H, Yumoto A, Shimomura M, Kobayashi H, Morita H, Shimbo M, Hamada M, Kudo T, Shinohara M, Asahara H, Shirakawa M, Takahashi S.

Sci Rep. 2017 Sep 7;7(1):10837. doi: 10.1038/s41598-017-10998-4.

23.

Bisulfite Sequencing for DNA Methylation Analysis of Primary Muscle Stem Cells.

Miyata K, Naito M, Miyata T, Mokuda S, Asahara H.

Methods Mol Biol. 2017;1668:3-13. doi: 10.1007/978-1-4939-7283-8_1.

24.

CDKL5 controls postsynaptic localization of GluN2B-containing NMDA receptors in the hippocampus and regulates seizure susceptibility.

Okuda K, Kobayashi S, Fukaya M, Watanabe A, Murakami T, Hagiwara M, Sato T, Ueno H, Ogonuki N, Komano-Inoue S, Manabe H, Yamaguchi M, Ogura A, Asahara H, Sakagami H, Mizuguchi M, Manabe T, Tanaka T.

Neurobiol Dis. 2017 Oct;106:158-170. doi: 10.1016/j.nbd.2017.07.002. Epub 2017 Jul 6.

PMID:
28688852
25.

Tendons and Ligaments: Connecting Developmental Biology to Musculoskeletal Disease Pathogenesis.

Asahara H, Inui M, Lotz MK.

J Bone Miner Res. 2017 Sep;32(9):1773-1782. doi: 10.1002/jbmr.3199. Epub 2017 Jul 13. Review.

26.

Long and branched polyamines are required for maintenance of the ribosome, tRNAHis and tRNATyr in Thermus thermophilus cells at high temperatures.

Nakashima M, Yamagami R, Tomikawa C, Ochi Y, Moriya T, Asahara H, Fourmy D, Yoshizawa S, Oshima T, Hori H.

Genes Cells. 2017 Jul;22(7):628-645. doi: 10.1111/gtc.12502. Epub 2017 May 24.

27.

Synthesis of Functionalized 3-Cyanoisoxazoles Using a Dianionic Reagent.

Iwai K, Asahara H, Nishiwaki N.

J Org Chem. 2017 May 19;82(10):5409-5415. doi: 10.1021/acs.joc.7b00811. Epub 2017 May 9.

PMID:
28471185
28.

Analysis of transcription factors expressed at the anterior mouse limb bud.

Yokoyama S, Furukawa S, Kitada S, Mori M, Saito T, Kawakami K, Belmonte JCI, Kawakami Y, Ito Y, Sato T, Asahara H.

PLoS One. 2017 May 3;12(5):e0175673. doi: 10.1371/journal.pone.0175673. eCollection 2017.

29.

Hydrohalogenation of Ethynylpyridines Involving Nucleophilic Attack of a Halide Ion.

Muragishi K, Asahara H, Nishiwaki N.

ACS Omega. 2017 Apr 4;2(4):1265-1272. doi: 10.1021/acsomega.7b00133. eCollection 2017 Apr 30.

30.

Identification of targets of tumor suppressor microRNA-34a using a reporter library system.

Ito Y, Inoue A, Seers T, Hato Y, Igarashi A, Toyama T, Taganov KD, Boldin MP, Asahara H.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3927-3932. doi: 10.1073/pnas.1620019114. Epub 2017 Mar 29.

31.

E3 ubiquitin ligases SIAH1/2 regulate hypoxia-inducible factor-1 (HIF-1)-mediated Th17 cell differentiation.

Matsui-Hasumi A, Sato Y, Uto-Konomi A, Yamashita S, Uehori J, Yoshimura A, Yamashita M, Asahara H, Suzuki S, Kubo M.

Int Immunol. 2017 Mar 1;29(3):133-143. doi: 10.1093/intimm/dxx014.

PMID:
28338984
32.

Bhlha9 regulates apical ectodermal ridge formation during limb development.

Kataoka K, Matsushima T, Ito Y, Sato T, Yokoyama S, Asahara H.

J Bone Miner Metab. 2018 Jan;36(1):64-72. doi: 10.1007/s00774-017-0820-0. Epub 2017 Mar 21.

33.

ARID2 modulates DNA damage response in human hepatocellular carcinoma cells.

Oba A, Shimada S, Akiyama Y, Nishikawaji T, Mogushi K, Ito H, Matsumura S, Aihara A, Mitsunori Y, Ban D, Ochiai T, Kudo A, Asahara H, Kaida A, Miura M, Tanabe M, Tanaka S.

J Hepatol. 2017 May;66(5):942-951. doi: 10.1016/j.jhep.2016.12.026. Epub 2017 Feb 24.

PMID:
28238438
34.

TWIST1 induces MMP3 expression through up-regulating DNA hydroxymethylation and promotes catabolic responses in human chondrocytes.

Hasei J, Teramura T, Takehara T, Onodera Y, Horii T, Olmer M, Hatada I, Fukuda K, Ozaki T, Lotz MK, Asahara H.

Sci Rep. 2017 Feb 21;7:42990. doi: 10.1038/srep42990.

35.

Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin.

Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M.

J Neurosci. 2017 Mar 22;37(12):3181-3191. doi: 10.1523/JNEUROSCI.3632-16.2017. Epub 2017 Feb 17.

36.

Tailor-made synthesis of fully alkylated/arylated nicotinates by FeCl3-mediated condensation of enamino esters with enones.

Hirai S, Horikawa Y, Asahara H, Nishiwaki N.

Chem Commun (Camb). 2017 Feb 16;53(15):2390-2393. doi: 10.1039/c7cc00051k.

PMID:
28174763
37.

Complementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction.

Nakasuji T, Ogonuki N, Chiba T, Kato T, Shiozawa K, Yamatoya K, Tanaka H, Kondo T, Miyado K, Miyasaka N, Kubota T, Ogura A, Asahara H.

PLoS Genet. 2017 Jan 23;13(1):e1006578. doi: 10.1371/journal.pgen.1006578. eCollection 2017 Jan.

38.

The transcription factor mohawk homeobox regulates homeostasis of the periodontal ligament.

Koda N, Sato T, Shinohara M, Ichinose S, Ito Y, Nakamichi R, Kayama T, Kataoka K, Suzuki H, Moriyama K, Asahara H.

Development. 2017 Jan 15;144(2):313-320. doi: 10.1242/dev.135798. Epub 2016 Dec 19.

39.

Deletion of conserved sequences in IG-DMR at Dlk1-Gtl2 locus suggests their involvement in expression of paternally expressed genes in mice.

Saito T, Hara S, Tamano M, Asahara H, Takada S.

J Reprod Dev. 2017 Feb 16;63(1):101-109. doi: 10.1262/jrd.2016-135. Epub 2016 Dec 1.

40.

Synthesis of 6-substituted 2-phenacylpyridines from 2-(phenylethynyl)pyridine via isoxazolo[2,3-a]pyridinium salt.

Le ST, Fujimoto T, Asahara H, Nishiwaki N.

Org Biomol Chem. 2016 Dec 7;14(45):10674-10682. Epub 2016 Oct 28.

PMID:
27790667
41.

Current Status and Strategy of microRNA Research for Cartilage Development and Osteoarthritis Pathogenesis.

Asahara H.

J Bone Metab. 2016 Aug;23(3):121-7. doi: 10.11005/jbm.2016.23.3.121. Epub 2016 Aug 31. Review.

42.

Reconstitution of Protein Translation of Mycobacterium Reveals Functional Conservation and Divergence with the Gram-Negative Bacterium Escherichia coli.

Srivastava A, Asahara H, Zhang M, Zhang W, Liu H, Cui S, Jin Q, Chong S.

PLoS One. 2016 Aug 26;11(8):e0162020. doi: 10.1371/journal.pone.0162020. eCollection 2016.

43.

Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs.

Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, Suzuki H, Mori M, Inagawa M, Ichinose S, Lotz MK, Sakai D, Masuda K, Ozaki T, Asahara H.

Nat Commun. 2016 Aug 16;7:12503. doi: 10.1038/ncomms12503.

44.

Dnmt3a Regulates Proliferation of Muscle Satellite Cells via p57Kip2.

Naito M, Mori M, Inagawa M, Miyata K, Hashimoto N, Tanaka S, Asahara H.

PLoS Genet. 2016 Jul 14;12(7):e1006167. doi: 10.1371/journal.pgen.1006167. eCollection 2016 Jul.

45.

Gene targeting of the transcription factor Mohawk in rats causes heterotopic ossification of Achilles tendon via failed tenogenesis.

Suzuki H, Ito Y, Shinohara M, Yamashita S, Ichinose S, Kishida A, Oyaizu T, Kayama T, Nakamichi R, Koda N, Yagishita K, Lotz MK, Okawa A, Asahara H.

Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7840-5. doi: 10.1073/pnas.1522054113. Epub 2016 Jul 1.

46.

Dual Behavior of Iodine Species in Condensation of Anilines and Vinyl Ethers Affording 2-Methylquinolines.

Le ST, Yasuoka C, Asahara H, Nishiwaki N.

Molecules. 2016 Jun 25;21(7). pii: E827. doi: 10.3390/molecules21070827.

47.

ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity.

Otero M, Peng H, Hachem KE, Culley KL, Wondimu EB, Quinn J, Asahara H, Tsuchimochi K, Hashimoto K, Goldring MB.

Connect Tissue Res. 2017 Jan;58(1):15-26. doi: 10.1080/03008207.2016.1200566. Epub 2016 Jun 16.

48.

Folate-/FAD-dependent tRNA methyltransferase from Thermus thermophilus regulates other modifications in tRNA at low temperatures.

Yamagami R, Tomikawa C, Shigi N, Kazayama A, Asai S, Takuma H, Hirata A, Fourmy D, Asahara H, Watanabe K, Yoshizawa S, Hori H.

Genes Cells. 2016 Jul;21(7):740-54. doi: 10.1111/gtc.12376. Epub 2016 May 30.

49.

A direct and vicinal functionalization of the 1-methyl-2-quinolone framework: 4-alkoxylation and 3-chlorination.

Hao F, Asahara H, Nishiwaki N.

Org Biomol Chem. 2016 Jun 14;14(22):5128-35. doi: 10.1039/c6ob00868b. Epub 2016 May 16.

PMID:
27181022
50.

Three-dimensional printing of continuous-fiber composites by in-nozzle impregnation.

Matsuzaki R, Ueda M, Namiki M, Jeong TK, Asahara H, Horiguchi K, Nakamura T, Todoroki A, Hirano Y.

Sci Rep. 2016 Mar 11;6:23058. doi: 10.1038/srep23058.

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