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Items: 39

1.

Cell Cycle Perturbation Induces Collagen Production in Fibroblasts.

Wake M, Takeda N, Isagawa T, Sato T, Nakagama Y, Morioka MS, Hirota Y, Asagiri M, Maemura K, Manabe I, Tanabe K, Komuro I.

Int Heart J. 2019 Jul 27;60(4):958-963. doi: 10.1536/ihj.18-710. Epub 2019 Jul 12.

2.

Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M.

Abe H, Takeda N, Isagawa T, Semba H, Nishimura S, Morioka MS, Nakagama Y, Sato T, Soma K, Koyama K, Wake M, Katoh M, Asagiri M, Neugent ML, Kim JW, Stockmann C, Yonezawa T, Inuzuka R, Hirota Y, Maemura K, Yamashita T, Otsu K, Manabe I, Nagai R, Komuro I.

Nat Commun. 2019 Jun 27;10(1):2824. doi: 10.1038/s41467-019-10859-w.

3.

Necrostatin-7 suppresses RANK-NFATc1 signaling and attenuates macrophage to osteoclast differentiation.

Fuji H, Ohmae S, Noma N, Takeiri M, Yasutomi H, Izumi K, Ito M, Toyomoto M, Iwaki S, Takemoto K, Seo S, Taura K, Hida S, Aoyama M, Ishihama Y, Hagiwara M, Takeda N, Hatano E, Iwaisako K, Uemoto S, Asagiri M.

Biochem Biophys Res Commun. 2018 Sep 5;503(2):544-549. doi: 10.1016/j.bbrc.2018.05.153. Epub 2018 Jul 7.

PMID:
29800570
4.

Pancreatic Stellate Cells Have Distinct Characteristics From Hepatic Stellate Cells and Are Not the Unique Origin of Collagen-Producing Cells in the Pancreas.

Yamamoto G, Taura K, Iwaisako K, Asagiri M, Ito S, Koyama Y, Tanabe K, Iguchi K, Satoh M, Nishio T, Okuda Y, Ikeno Y, Yoshino K, Seo S, Hatano E, Uemoto S.

Pancreas. 2017 Oct;46(9):1141-1151. doi: 10.1097/MPA.0000000000000901.

PMID:
28902784
5.

Gallbladder-derived surfactant protein D regulates gut commensal bacteria for maintaining intestinal homeostasis.

Sarashina-Kida H, Negishi H, Nishio J, Suda W, Nakajima Y, Yasui-Kato M, Iwaisako K, Kang S, Endo N, Yanai H, Asagiri M, Kida H, Hattori M, Kumanogoh A, Taniguchi T.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10178-10183. doi: 10.1073/pnas.1712837114. Epub 2017 Sep 6.

6.

Actin-binding protein coronin 1A controls osteoclastic bone resorption by regulating lysosomal secretion of cathepsin K.

Ohmae S, Noma N, Toyomoto M, Shinohara M, Takeiri M, Fuji H, Takemoto K, Iwaisako K, Fujita T, Takeda N, Kawatani M, Aoyama M, Hagiwara M, Ishihama Y, Asagiri M.

Sci Rep. 2017 Mar 16;7:41710. doi: 10.1038/srep41710.

7.

Hepatic vagus nerve regulates Kupffer cell activation via α7 nicotinic acetylcholine receptor in nonalcoholic steatohepatitis.

Nishio T, Taura K, Iwaisako K, Koyama Y, Tanabe K, Yamamoto G, Okuda Y, Ikeno Y, Yoshino K, Kasai Y, Okuno M, Seo S, Sakurai T, Asagiri M, Hatano E, Uemoto S.

J Gastroenterol. 2017 Aug;52(8):965-976. doi: 10.1007/s00535-016-1304-z. Epub 2017 Jan 2.

PMID:
28044208
8.

HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity.

Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, Miyazawa H, Yamaguchi Y, Miura M, Jenkins DM, Choi H, Kim JW, Asagiri M, Cowburn AS, Abe H, Soma K, Koyama K, Katoh M, Sayama K, Goda N, Johnson RS, Manabe I, Nagai R, Komuro I.

Nat Commun. 2016 May 18;7:11635. doi: 10.1038/ncomms11635.

9.

Mice lacking the intracellular cation channel TRIC-B have compromised collagen production and impaired bone mineralization.

Zhao C, Ichimura A, Qian N, Iida T, Yamazaki D, Noma N, Asagiri M, Yamamoto K, Komazaki S, Sato C, Aoyama F, Sawaguchi A, Kakizawa S, Nishi M, Takeshima H.

Sci Signal. 2016 May 17;9(428):ra49. doi: 10.1126/scisignal.aad9055.

PMID:
27188440
10.

B-cell survival and development controlled by the coordination of NF-κB family members RelB and cRel.

Almaden JV, Liu YC, Yang E, Otero DC, Birnbaum H, Davis-Turak J, Asagiri M, David M, Goldrath AW, Hoffmann A.

Blood. 2016 Mar 10;127(10):1276-86. doi: 10.1182/blood-2014-10-606988. Epub 2016 Jan 14.

11.

Hepatic stellate cells relay inflammation signaling from sinusoids to parenchyma in mouse models of immune-mediated hepatitis.

Fujita T, Soontrapa K, Ito Y, Iwaisako K, Moniaga CS, Asagiri M, Majima M, Narumiya S.

Hepatology. 2016 Apr;63(4):1325-39. doi: 10.1002/hep.28112. Epub 2015 Sep 30.

12.

Efficient inhibition of tumor angiogenesis and growth by a synthetic peptide blocking S100A4-methionine aminopeptidase 2 interaction.

Ochiya T, Takenaga K, Asagiri M, Nakano K, Satoh H, Watanabe T, Imajoh-Ohmi S, Endo H.

Mol Ther Methods Clin Dev. 2015 Apr 1;2:15008. doi: 10.1038/mtm.2015.8. eCollection 2015.

13.

Inhibition of MMP-2-Mediated Mast Cell Invasion by NF-κB Inhibitor DHMEQ in Mast Cells.

Noma N, Asagiri M, Takeiri M, Ohmae S, Takemoto K, Iwaisako K, Minato N, Maeda-Yamamoto M, Simizu S, Umezawa K.

Int Arch Allergy Immunol. 2015;166(2):84-90. doi: 10.1159/000371419. Epub 2015 Mar 13.

14.

Migration of splenic lymphocytes promotes liver fibrosis through modification of T helper cytokine balance in mice.

Tanabe K, Taura K, Koyama Y, Yamamoto G, Nishio T, Okuda Y, Nakamura K, Toriguchi K, Takemoto K, Yamanaka K, Iwaisako K, Seo S, Asagiri M, Hatano E, Uemoto S.

J Gastroenterol. 2015 Oct;50(10):1054-68. doi: 10.1007/s00535-015-1054-3. Epub 2015 Feb 28.

PMID:
25724556
15.

Strategies to Detect Hepatic Myofibroblasts in Liver Cirrhosis of Different Etiologies.

Iwaisako K, Taura K, Koyama Y, Takemoto K, Asagiri M.

Curr Pathobiol Rep. 2014;2(4):209-215. Review.

16.

Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure.

Takemoto K, Hatano E, Iwaisako K, Takeiri M, Noma N, Ohmae S, Toriguchi K, Tanabe K, Tanaka H, Seo S, Taura K, Machida K, Takeda N, Saji S, Uemoto S, Asagiri M.

FEBS Open Bio. 2014 Sep 6;4:777-87. doi: 10.1016/j.fob.2014.08.007. eCollection 2014.

17.

Origin of myofibroblasts in the fibrotic liver in mice.

Iwaisako K, Jiang C, Zhang M, Cong M, Moore-Morris TJ, Park TJ, Liu X, Xu J, Wang P, Paik YH, Meng F, Asagiri M, Murray LA, Hofmann AF, Iida T, Glass CK, Brenner DA, Kisseleva T.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3297-305. doi: 10.1073/pnas.1400062111. Epub 2014 Jul 29.

18.

Generation of a mouse model with down-regulated U50 snoRNA (SNORD50) expression and its organ-specific phenotypic modulation.

Soeno Y, Fujita K, Kudo T, Asagiri M, Kakuta S, Taya Y, Shimazu Y, Sato K, Tanaka-Fujita R, Kubo S, Iwakura Y, Nakamura Y, Mori S, Aoba T.

PLoS One. 2013 Aug 26;8(8):e72105. doi: 10.1371/journal.pone.0072105. eCollection 2013.

19.

Cilostazol attenuates hepatic stellate cell activation and protects mice against carbon tetrachloride-induced liver fibrosis.

Saito S, Hata K, Iwaisako K, Yanagida A, Takeiri M, Tanaka H, Kageyama S, Hirao H, Ikeda K, Asagiri M, Uemoto S.

Hepatol Res. 2014 Apr;44(4):460-73. doi: 10.1111/hepr.12140. Epub 2013 Jun 30.

20.

Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways.

Shih VF, Davis-Turak J, Macal M, Huang JQ, Ponomarenko J, Kearns JD, Yu T, Fagerlund R, Asagiri M, Zuniga EI, Hoffmann A.

Nat Immunol. 2012 Dec;13(12):1162-70. doi: 10.1038/ni.2446. Epub 2012 Oct 21.

21.

The transcriptional specificity of NF-κB dimers is coded within the κB DNA response elements.

Wang VY, Huang W, Asagiri M, Spann N, Hoffmann A, Glass C, Ghosh G.

Cell Rep. 2012 Oct 25;2(4):824-39. doi: 10.1016/j.celrep.2012.08.042. Epub 2012 Oct 11.

22.

Epidermal phospholipase Cδ1 regulates granulocyte counts and systemic interleukin-17 levels in mice.

Kanemaru K, Nakamura Y, Sato K, Kojima R, Takahashi S, Yamaguchi M, Ichinohe M, Kiyonari H, Shioi G, Kabashima K, Nakahigashi K, Asagiri M, Jamora C, Yamaguchi H, Fukami K.

Nat Commun. 2012 Jul 17;3:963. doi: 10.1038/ncomms1960.

PMID:
22805570
23.

NF-κB potentiates caspase independent hydrogen peroxide induced cell death.

Ho JQ, Asagiri M, Hoffmann A, Ghosh G.

PLoS One. 2011 Feb 15;6(2):e16815. doi: 10.1371/journal.pone.0016815.

24.

Axonal-transport-mediated gene transduction in the interior of rat bone.

Okabayashi T, Nakanishi K, Tsuchihara T, Arino H, Yoshihara Y, Tominaga S, Uenoyama M, Suzuki S, Asagiri M, Nemoto K.

PLoS One. 2010 Sep 28;5(9). pii: e13034. doi: 10.1371/journal.pone.0013034.

25.

Defective regulation of CXCR2 facilitates neutrophil release from bone marrow causing spontaneous inflammation in severely NF-kappa B-deficient mice.

von Vietinghoff S, Asagiri M, Azar D, Hoffmann A, Ley K.

J Immunol. 2010 Jul 1;185(1):670-8. doi: 10.4049/jimmunol.1000339. Epub 2010 Jun 2.

26.

Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis.

Takeda N, O'Dea EL, Doedens A, Kim JW, Weidemann A, Stockmann C, Asagiri M, Simon MC, Hoffmann A, Johnson RS.

Genes Dev. 2010 Mar 1;24(5):491-501. doi: 10.1101/gad.1881410.

27.

Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.

Asagiri M, Hirai T, Kunigami T, Kamano S, Gober HJ, Okamoto K, Nishikawa K, Latz E, Golenbock DT, Aoki K, Ohya K, Imai Y, Morishita Y, Miyazono K, Kato S, Saftig P, Takayanagi H.

Science. 2008 Feb 1;319(5863):624-7. doi: 10.1126/science.1150110.

28.

The molecular understanding of osteoclast differentiation.

Asagiri M, Takayanagi H.

Bone. 2007 Feb;40(2):251-64. Epub 2006 Nov 13. Review.

PMID:
17098490
29.

Autoamplification of NFATc1 expression determines its essential role in bone homeostasis.

Asagiri M, Sato K, Usami T, Ochi S, Nishina H, Yoshida H, Morita I, Wagner EF, Mak TW, Serfling E, Takayanagi H.

J Exp Med. 2005 Nov 7;202(9):1261-9.

31.

NFAT and Osterix cooperatively regulate bone formation.

Koga T, Matsui Y, Asagiri M, Kodama T, de Crombrugghe B, Nakashima K, Takayanagi H.

Nat Med. 2005 Aug;11(8):880-5. Epub 2005 Jul 24.

PMID:
16041384
32.

IRF-7 is the master regulator of type-I interferon-dependent immune responses.

Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, Shimada N, Ohba Y, Takaoka A, Yoshida N, Taniguchi T.

Nature. 2005 Apr 7;434(7034):772-7. Epub 2005 Mar 30.

33.

Inhibition of RANKL-induced osteoclastogenesis by (-)-DHMEQ, a novel NF-kappaB inhibitor, through downregulation of NFATc1.

Takatsuna H, Asagiri M, Kubota T, Oka K, Osada T, Sugiyama C, Saito H, Aoki K, Ohya K, Takayanagi H, Umezawa K.

J Bone Miner Res. 2005 Apr;20(4):653-62. Epub 2004 Dec 6.

34.

Regulation of FGF receptor-2 expression by transcription factor E2F-1.

Tashiro E, Minato Y, Maruki H, Asagiri M, Imoto M.

Oncogene. 2003 Aug 28;22(36):5630-5.

PMID:
12944911
35.

Essential role of IRF-3 in lipopolysaccharide-induced interferon-beta gene expression and endotoxin shock.

Sakaguchi S, Negishi H, Asagiri M, Nakajima C, Mizutani T, Takaoka A, Honda K, Taniguchi T.

Biochem Biophys Res Commun. 2003 Jul 11;306(4):860-6.

PMID:
12821121
36.

Constitutive IFN-alpha/beta signal for efficient IFN-alpha/beta gene induction by virus.

Hata N, Sato M, Takaoka A, Asagiri M, Tanaka N, Taniguchi T.

Biochem Biophys Res Commun. 2001 Jul 13;285(2):518-25.

PMID:
11444873
37.

Gene induction pathways mediated by distinct IRFs during viral infection.

Nakaya T, Sato M, Hata N, Asagiri M, Suemori H, Noguchi S, Tanaka N, Taniguchi T.

Biochem Biophys Res Commun. 2001 May 25;283(5):1150-6.

PMID:
11355893
38.

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction.

Sato M, Suemori H, Hata N, Asagiri M, Ogasawara K, Nakao K, Nakaya T, Katsuki M, Noguchi S, Tanaka N, Taniguchi T.

Immunity. 2000 Oct;13(4):539-48.

39.

Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7.

Sato M, Hata N, Asagiri M, Nakaya T, Taniguchi T, Tanaka N.

FEBS Lett. 1998 Dec 11;441(1):106-10.

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