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Items: 7


Mitochondrial Network State Scales mDNA Genetic Dynamics.

Aryaman J, Bowles C, Jones NS, Johnston IG.

Genetics. 2019 Aug;212(4):1429-1443. doi: 10.1534/genetics.119.302423. Epub 2019 Jun 28.


Mitochondrial Heterogeneity.

Aryaman J, Johnston IG, Jones NS.

Front Genet. 2019 Jan 25;9:718. doi: 10.3389/fgene.2018.00718. eCollection 2018. Review.


High prevalence of focal and multi-focal somatic genetic variants in the human brain.

Keogh MJ, Wei W, Aryaman J, Walker L, van den Ameele J, Coxhead J, Wilson I, Bashton M, Beck J, West J, Chen R, Haudenschild C, Bartha G, Luo S, Morris CM, Jones NS, Attems J, Chinnery PF.

Nat Commun. 2018 Oct 15;9(1):4257. doi: 10.1038/s41467-018-06331-w.


Frequency and signature of somatic variants in 1461 human brain exomes.

Wei W, Keogh MJ, Aryaman J, Golder Z, Kullar PJ, Wilson I, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, Sarraj SA, Morris CM, Ansorge O, Jones NS, Ironside JW, Chinnery PF.

Genet Med. 2019 Apr;21(4):904-912. doi: 10.1038/s41436-018-0274-3. Epub 2018 Sep 14.


Oligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains.

Keogh MJ, Wei W, Aryaman J, Wilson I, Talbot K, Turner MR, McKenzie CA, Troakes C, Attems J, Smith C, Al Sarraj S, Morris CM, Ansorge O, Pickering-Brown S, Jones N, Ironside JW, Chinnery PF.

J Neurol Neurosurg Psychiatry. 2018 Aug;89(8):813-816. doi: 10.1136/jnnp-2017-317234. Epub 2018 Jan 13.


Mitochondrial DNA density homeostasis accounts for a threshold effect in a cybrid model of a human mitochondrial disease.

Aryaman J, Johnston IG, Jones NS.

Biochem J. 2017 Nov 24;474(23):4019-4034. doi: 10.1042/BCJ20170651.


Mitochondrial heterogeneity, metabolic scaling and cell death.

Aryaman J, Hoitzing H, Burgstaller JP, Johnston IG, Jones NS.

Bioessays. 2017 Jul;39(7). doi: 10.1002/bies.201700001. Epub 2017 Jun 8. Review.

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