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Items: 20

1.

Structural basis for delta cell paracrine regulation in pancreatic islets.

Arrojo E Drigo R, Jacob S, García-Prieto CF, Zheng X, Fukuda M, Nhu HTT, Stelmashenko O, Peçanha FLM, Rodriguez-Diaz R, Bushong E, Deerinck T, Phan S, Ali Y, Leibiger I, Chua M, Boudier T, Song SH, Graf M, Augustine GJ, Ellisman MH, Berggren PO.

Nat Commun. 2019 Aug 16;10(1):3700. doi: 10.1038/s41467-019-11517-x. Erratum in: Nat Commun. 2019 Sep 11;10(1):4218.

2.

Age Mosaicism across Multiple Scales in Adult Tissues.

Arrojo E Drigo R, Lev-Ram V, Tyagi S, Ramachandra R, Deerinck T, Bushong E, Phan S, Orphan V, Lechene C, Ellisman MH, Hetzer MW.

Cell Metab. 2019 Aug 6;30(2):343-351.e3. doi: 10.1016/j.cmet.2019.05.010. Epub 2019 Jun 6.

PMID:
31178361
3.

Visualization of long-lived proteins reveals age mosaicism within nuclei of postmitotic cells.

Toyama BH, Arrojo E Drigo R, Lev-Ram V, Ramachandra R, Deerinck TJ, Lechene C, Ellisman MH, Hetzer MW.

J Cell Biol. 2019 Feb 4;218(2):433-444. doi: 10.1083/jcb.201809123. Epub 2018 Dec 14.

4.

Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function.

Yu G, Tzouvelekis A, Wang R, Herazo-Maya JD, Ibarra GH, Srivastava A, de Castro JPW, DeIuliis G, Ahangari F, Woolard T, Aurelien N, Arrojo E Drigo R, Gan Y, Graham M, Liu X, Homer RJ, Scanlan TS, Mannam P, Lee PJ, Herzog EL, Bianco AC, Kaminski N.

Nat Med. 2018 Jan;24(1):39-49. doi: 10.1038/nm.4447. Epub 2017 Dec 4.

5.

Pancreatic Islet Blood Flow Dynamics in Primates.

Diez JA, Arrojo E Drigo R, Zheng X, Stelmashenko OV, Chua M, Rodriguez-Diaz R, Fukuda M, Köhler M, Leibiger I, Tun SBB, Ali Y, Augustine GJ, Barathi VA, Berggren PO.

Cell Rep. 2017 Aug 8;20(6):1490-1501. doi: 10.1016/j.celrep.2017.07.039.

6.

A novel toolbox to investigate tissue spatial organization applied to the study of the islets of Langerhans.

Tran Thi Nhu H, Arrojo E Drigo R, Berggren PO, Boudier T.

Sci Rep. 2017 Mar 17;7:44261. doi: 10.1038/srep44261.

7.

New insights into the architecture of the islet of Langerhans: a focused cross-species assessment.

Arrojo e Drigo R, Ali Y, Diez J, Srinivasan DK, Berggren PO, Boehm BO.

Diabetologia. 2015 Oct;58(10):2218-28. doi: 10.1007/s00125-015-3699-0. Epub 2015 Jul 28. Review.

PMID:
26215305
8.

Young capillary vessels rejuvenate aged pancreatic islets.

Almaça J, Molina J, Arrojo E Drigo R, Abdulreda MH, Jeon WB, Berggren PO, Caicedo A, Nam HG.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17612-7. doi: 10.1073/pnas.1414053111. Epub 2014 Nov 17.

9.

The type II deiodinase is retrotranslocated to the cytoplasm and proteasomes via p97/Atx3 complex.

Arrojo E Drigo R, Egri P, Jo S, Gereben B, Bianco AC.

Mol Endocrinol. 2013 Dec;27(12):2105-15. doi: 10.1210/me.2013-1281. Epub 2013 Nov 6.

10.

Coordination of hypothalamic and pituitary T3 production regulates TSH expression.

Fonseca TL, Correa-Medina M, Campos MP, Wittmann G, Werneck-de-Castro JP, Arrojo e Drigo R, Mora-Garzon M, Ueta CB, Caicedo A, Fekete C, Gereben B, Lechan RM, Bianco AC.

J Clin Invest. 2013 Apr;123(4):1492-500. doi: 10.1172/JCI61231. Epub 2013 Mar 25.

11.

Role of the type 2 iodothyronine deiodinase (D2) in the control of thyroid hormone signaling.

Arrojo E Drigo R, Fonseca TL, Werneck-de-Castro JP, Bianco AC.

Biochim Biophys Acta. 2013 Jul;1830(7):3956-64. doi: 10.1016/j.bbagen.2012.08.019. Epub 2012 Aug 29. Review.

12.

Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism.

Jo S, Kalló I, Bardóczi Z, Arrojo e Drigo R, Zeöld A, Liposits Z, Oliva A, Lemmon VP, Bixby JL, Gereben B, Bianco AC.

J Neurosci. 2012 Jun 20;32(25):8491-500. doi: 10.1523/JNEUROSCI.6514-11.2012.

13.

A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons.

Kalló I, Mohácsik P, Vida B, Zeöld A, Bardóczi Z, Zavacki AM, Farkas E, Kádár A, Hrabovszky E, Arrojo E Drigo R, Dong L, Barna L, Palkovits M, Borsay BA, Herczeg L, Lechan RM, Bianco AC, Liposits Z, Fekete C, Gereben B.

PLoS One. 2012;7(6):e37860. doi: 10.1371/journal.pone.0037860. Epub 2012 Jun 18.

14.

Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis.

Arrojo E Drigo R, Fonseca TL, Castillo M, Salathe M, Simovic G, Mohácsik P, Gereben B, Bianco AC.

Mol Endocrinol. 2011 Dec;25(12):2065-75. doi: 10.1210/me.2011-1061. Epub 2011 Nov 3.

15.

Type 2 deiodinase at the crossroads of thyroid hormone action.

Arrojo E Drigo R, Bianco AC.

Int J Biochem Cell Biol. 2011 Oct;43(10):1432-41. doi: 10.1016/j.biocel.2011.05.016. Epub 2011 Jun 12. Review.

16.

The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure.

da-Silva WS, Ribich S, Arrojo e Drigo R, Castillo M, Patti ME, Bianco AC.

FEBS Lett. 2011 Feb 4;585(3):539-44. doi: 10.1016/j.febslet.2010.12.044. Epub 2011 Jan 14.

17.

Inhibition of the type 2 iodothyronine deiodinase underlies the elevated plasma TSH associated with amiodarone treatment.

Rosene ML, Wittmann G, Arrojo e Drigo R, Singru PS, Lechan RM, Bianco AC.

Endocrinology. 2010 Dec;151(12):5961-70. doi: 10.1210/en.2010-0553. Epub 2010 Oct 6.

18.

Knockdown of the type 3 iodothyronine deiodinase (D3) interacting protein peroxiredoxin 3 decreases D3-mediated deiodination in intact cells.

Aerts G, Arrojo E Drigo R, Van Herck SL, Sammels E, Mirebeau-Prunier D, Gereben B, Zeöld A, Harney JW, Huang SA, Mulcahey MA, Van der Geyten S, Van den Bergh G, Arckens L, Darras VM, Zavacki AM.

Endocrinology. 2009 Nov;150(11):5171-80. doi: 10.1210/en.2009-0702. Epub 2009 Oct 9.

19.

The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase.

Zavacki AM, Arrojo E Drigo R, Freitas BC, Chung M, Harney JW, Egri P, Wittmann G, Fekete C, Gereben B, Bianco AC.

Mol Cell Biol. 2009 Oct;29(19):5339-47. doi: 10.1128/MCB.01498-08. Epub 2009 Aug 3.

20.

Mice with impaired extrathyroidal thyroxine to 3,5,3'-triiodothyronine conversion maintain normal serum 3,5,3'-triiodothyronine concentrations.

Christoffolete MA, Arrojo e Drigo R, Gazoni F, Tente SM, Goncalves V, Amorim BS, Larsen PR, Bianco AC, Zavacki AM.

Endocrinology. 2007 Mar;148(3):954-60. Epub 2006 Nov 30.

PMID:
17138654

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