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Items: 29

1.

Discovery of a Fluorinated Enigmol Analog with Enhanced in Vivo Pharmacokinetic and Anti-Tumor Properties.

Miller EJ, Mays SG, Baillie MT, Howard RB, Culver DG, Saindane M, Pruett ST, Holt JJ, Menaldino DS, Evers TJ, Reddy GP, Arrendale RF, Natchus MG, Petros JA, Liotta DC.

ACS Med Chem Lett. 2016 Mar 21;7(5):537-42. doi: 10.1021/acsmedchemlett.6b00113. eCollection 2016 May 12.

2.

Discovery of tetrahydroisoquinoline-based CXCR4 antagonists.

Truax VM, Zhao H, Katzman BM, Prosser AR, Alcaraz AA, Saindane MT, Howard RB, Culver D, Arrendale RF, Gruddanti PR, Evers TJ, Natchus MG, Snyder JP, Liotta DC, Wilson LJ.

ACS Med Chem Lett. 2013 Sep 5;4(11):1025-30. doi: 10.1021/ml400183q. eCollection 2013 Nov 14.

3.

An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model.

Krumm SA, Yan D, Hovingh ES, Evers TJ, Enkirch T, Reddy GP, Sun A, Saindane MT, Arrendale RF, Painter G, Liotta DC, Natchus MG, von Messling V, Plemper RK.

Sci Transl Med. 2014 Apr 16;6(232):232ra52. doi: 10.1126/scitranslmed.3008517.

4.

Effect of protein binding on unbound atazanavir and darunavir cerebrospinal fluid concentrations.

Delille CA, Pruett ST, Marconi VC, Lennox JL, Armstrong WS, Arrendale RF, Sheth AN, Easley KA, Acosta EP, Vunnava A, Ofotokun I.

J Clin Pharmacol. 2014 Sep;54(9):1063-71. doi: 10.1002/jcph.298. Epub 2014 Apr 8.

5.

Synthetic curcumin analog UBS109 inhibits the growth of head and neck squamous cell carcinoma xenografts.

Zhu S, Moore TW, Morii N, Howard RB, Culver D, Arrendale RF, Reddy P, Evers TJ, Zhang H, Sica G, Chen ZG, Sun A, Fu H, Khuri FR, Shin DM, Snyder JP, Shoji M.

Curr Cancer Drug Targets. 2014;14(4):380-93.

PMID:
24628271
6.

Synthesis and Metabolic Studies of Host Directed Inhibitors for Anti Viral Therapy.

Moore TW, Sana K, Yan D, Krumm SA, Thepchatri P, Snyder JP, Marengo J, Arrendale RF, Prussia AJ, Natchus MG, Liotta DC, Plemper RK, Sun A.

ACS Med Chem Lett. 2013 Aug 8;4(8):762-767.

7.

Water-soluble progesterone analogues are effective, injectable treatments in animal models of traumatic brain injury.

Guthrie DB, Stein DG, Liotta DC, Lockwood MA, Sayeed I, Atif F, Arrendale RF, Reddy GP, Evers TJ, Marengo JR, Howard RB, Culver DG, Natchus MG.

ACS Med Chem Lett. 2012 Mar 15;3(5):362-6. doi: 10.1021/ml200303r. eCollection 2012 May 10.

8.

Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts.

Zhu S, Moore TW, Lin X, Morii N, Mancini A, Howard RB, Culver D, Arrendale RF, Reddy P, Evers TJ, Zhang H, Sica G, Chen ZG, Sun A, Fu H, Khuri FR, Shin DM, Snyder JP, Shoji M.

Integr Biol (Camb). 2012 Jun;4(6):633-40. doi: 10.1039/c2ib20007d. Epub 2012 Apr 25.

9.

Development of a unique small molecule modulator of CXCR4.

Liang Z, Zhan W, Zhu A, Yoon Y, Lin S, Sasaki M, Klapproth JM, Yang H, Grossniklaus HE, Xu J, Rojas M, Voll RJ, Goodman MM, Arrendale RF, Liu J, Yun CC, Snyder JP, Liotta DC, Shim H.

PLoS One. 2012;7(4):e34038. doi: 10.1371/journal.pone.0034038. Epub 2012 Apr 2.

10.

Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase: synthesis, structure-activity relationships, and pharmacokinetics.

Ndungu JM, Krumm SA, Yan D, Arrendale RF, Reddy GP, Evers T, Howard R, Natchus MG, Saindane MT, Liotta DC, Plemper RK, Snyder JP, Sun A.

J Med Chem. 2012 May 10;55(9):4220-30. doi: 10.1021/jm201699w. Epub 2012 Apr 20.

11.

Sphingolipid analogues inhibit development of malaria parasites.

Meyer EV, Holt JJ, Girard KR, Ballie MT, Bushnev AS, Lapp S, Menaldino DS, Arrendale RF, Reddy GP, Evers TJ, Howard RB, Culver DG, Liotta DC, Galinski MR, Natchus MG.

ACS Med Chem Lett. 2011 Dec 6;3(1):43-7. doi: 10.1021/ml2002136. eCollection 2012 Jan 12.

12.

Novel synthesis and biological evaluation of enigmols as therapeutic agents for treating prostate cancer.

Garnier-Amblard EC, Mays SG, Arrendale RF, Baillie MT, Bushnev AS, Culver DG, Evers TJ, Holt JJ, Howard RB, Liebeskind LS, Menaldino DS, Natchus MG, Petros JA, Ramaraju H, Reddy GP, Liotta DC.

ACS Med Chem Lett. 2011 Mar 25;2(6):438-43. doi: 10.1021/ml2000164. eCollection 2011 Jun 9.

13.

Selective inhibition of endothelial and monocyte redox-sensitive genes by AGI-1067: a novel antioxidant and anti-inflammatory agent.

Kunsch C, Luchoomun J, Grey JY, Olliff LK, Saint LB, Arrendale RF, Wasserman MA, Saxena U, Medford RM.

J Pharmacol Exp Ther. 2004 Mar;308(3):820-9. Epub 2003 Nov 14.

PMID:
14617690
14.

Determination of testosterone and 6beta-hydroxytestosterone by gas chromatography-selected ion monitoring-mass spectrometry for the characterization of cytochrome p450 3A activity.

Testino SA Jr, Ozarowski J, Thurston AW, Arrendale RF, Patonay G.

J Chromatogr B Biomed Sci Appl. 1999 Oct 29;734(1):73-81.

PMID:
10574192
15.

Stereospecific determinations of (+/- )-DU-124884 and its metabolites (+/- )-KC-9048 in human plasma by liquid chromatography.

Naidong W, Pullen RH, Arrendale RF, Brennan JJ, Hulse JD, Lee JW.

J Pharm Biomed Anal. 1996 Jan;14(3):325-37.

PMID:
8851757
16.

Determination of remifentanil in human blood by liquid-liquid extraction and capillary GC-HRMS-SIM using a deuterated internal standard.

Grosse CM, Davis IM, Arrendale RF, Jersey J, Amin J.

J Pharm Biomed Anal. 1994 Feb;12(2):195-203.

PMID:
8003546
17.

Caffeoyltartronic acid from catnip (Nepeta cataria): A precursor for catechol in lubber grasshopper (Romalea guttata) defensive secretions.

Snook ME, Blum MS, Whitman DW, Arrendale RF, Costello CE, Harwood JS.

J Chem Ecol. 1993 Sep;19(9):1957-66. doi: 10.1007/BF00983799.

PMID:
24249371
18.

Effects of the pre-column in automated on-column injection capillary gas chromatography.

Arrendale RF, Stewart JT, Martin RM.

J Chromatogr. 1990 Oct 5;518(2):307-18.

PMID:
2254387
19.

A generalist herbivore in a specialist mode Metabolic, sequestrative, and defensive consequences.

Blum MS, Severson RF, Arrendale RF, Whitman DW, Escoubas P, Adeyeye O, Jones CG.

J Chem Ecol. 1990 Jan;16(1):223-44. doi: 10.1007/BF01021281.

PMID:
24264909
20.

Relationship of plasma clonidine to growth hormone concentrations in children and adolescents.

Hoffman WH, DiPiro JT, Tackett RL, Arrendale RF, Hahn DA.

J Clin Pharmacol. 1989 Jun;29(6):538-42.

PMID:
2754022
21.

Attraction of adult sweet potato weevils,Cylas formicarius elegantulus (Summers), (Coleoptera: Curculionidae), to sweet potato leaf and root volatiles.

Nottingham SF, Son KC, Severson RF, Arrendale RF, Kays SJ.

J Chem Ecol. 1989 Mar;15(3):1095-106. doi: 10.1007/BF01015202.

PMID:
24271909
22.
23.
24.

Identification of tobacco hornworm antibiosis factor from cuticulae of repandae section ofNicotiana species.

Severson RF, Huesing JE, Jones D, Arrendale RF, Sisson VA.

J Chem Ecol. 1988 Jun;14(6):1485-94. doi: 10.1007/BF01012420.

PMID:
24276399
25.

Biotransformation of the antiestrogen clomiphene to chemically reactive metabolites in the immature female rat.

Ruenitz PC, Arrendale RF, George GD, Thompson CB, Mokler CM, Nanavati NT.

Cancer Res. 1987 Aug 1;47(15):4015-9.

26.

Isolation of compactin (a hypocholestrolemic metabolite) from a new source: Penicillium cyclopium.

Doss SL, Chu CK, Mesbah MK, Cutler HG, Cole PD, Arrendale RF, Springer JP.

J Nat Prod. 1986 Mar-Apr;49(2):357-8. No abstract available.

PMID:
3734817
27.

Isolation of indoles and carbazoles from cigarette smoke condensate.

Snook ME, Arrendale RF, Higman HC, Chortyk OT.

Anal Chem. 1978 Jan;50(1):88-90. No abstract available.

PMID:
619701
28.

Gas chromatographic method for the determination of free and total solanesol in tabacco.

Severson RF, Ellington JJ, Schlotzhauer PF, Arrendale RF, Schepartz AI.

J Chromatogr. 1977 Sep 21;139(2):269-82.

PMID:
893618
29.

Gas chromatographic quantitation of polynuclear aromatic hydrocarbons in tobacco smoke.

Severson RF, Snook ME, Arrendale RF, Chortyk OT.

Anal Chem. 1976 Nov;48(13):1866-72. No abstract available.

PMID:
970639

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