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Items: 1 to 50 of 54

1.

Distinct Phenotypes Induced by Three Degrees of Transverse Aortic Constriction in Mice.

Richards DA, Aronovitz MJ, Calamaras TD, Tam K, Martin GL, Liu P, Bowditch HK, Zhang P, Huggins GS, Blanton RM.

Sci Rep. 2019 Apr 10;9(1):5844. doi: 10.1038/s41598-019-42209-7.

2.

Mixed lineage kinase-3 prevents cardiac dysfunction and structural remodeling with pressure overload.

Calamaras TD, Baumgartner RA, Aronovitz MJ, McLaughlin AL, Tam K, Richards DA, Cooper CW, Li N, Baur WE, Qiao X, Wang GR, Davis RJ, Kapur NK, Karas RH, Blanton RM.

Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H145-H159. doi: 10.1152/ajpheart.00029.2018. Epub 2018 Oct 26.

3.

Membrane-Initiated Estrogen Receptor Signaling Mediates Metabolic Homeostasis via Central Activation of Protein Phosphatase 2A.

Ueda K, Takimoto E, Lu Q, Liu P, Fukuma N, Adachi Y, Suzuki R, Chou S, Baur W, Aronovitz MJ, Greenberg AS, Komuro I, Karas RH.

Diabetes. 2018 Aug;67(8):1524-1537. doi: 10.2337/db17-1342. Epub 2018 May 15.

4.

Bone Morphogenetic Protein 9 Reduces Cardiac Fibrosis and Improves Cardiac Function in Heart Failure.

Morine KJ, Qiao X, York S, Natov PS, Paruchuri V, Zhang Y, Aronovitz MJ, Karas RH, Kapur NK.

Circulation. 2018 Jul 31;138(5):513-526. doi: 10.1161/CIRCULATIONAHA.117.031635.

5.

Reduced activin receptor-like kinase 1 activity promotes cardiac fibrosis in heart failure.

Morine KJ, Qiao X, Paruchuri V, Aronovitz MJ, Mackey EE, Buiten L, Levine J, Ughreja K, Nepali P, Blanton RM, Oh SP, Karas RH, Kapur NK.

Cardiovasc Pathol. 2017 Nov - Dec;31:26-33. doi: 10.1016/j.carpath.2017.07.004. Epub 2017 Jul 18.

6.

Conditional knockout of activin like kinase-1 (ALK-1) leads to heart failure without maladaptive remodeling.

Morine KJ, Qiao X, Paruchuri V, Aronovitz MJ, Mackey EE, Buiten L, Levine J, Ughreja K, Nepali P, Blanton RM, Karas RH, Oh SP, Kapur NK.

Heart Vessels. 2017 May;32(5):628-636. doi: 10.1007/s00380-017-0955-x. Epub 2017 Feb 17.

7.

MicroRNA-Offset RNA Alters Gene Expression and Cell Proliferation.

Zhao J, Schnitzler GR, Iyer LK, Aronovitz MJ, Baur WE, Karas RH.

PLoS One. 2016 Jun 8;11(6):e0156772. doi: 10.1371/journal.pone.0156772. eCollection 2016.

8.

Reducing endoglin activity limits calcineurin and TRPC-6 expression and improves survival in a mouse model of right ventricular pressure overload.

Kapur NK, Qiao X, Paruchuri V, Mackey EE, Daly GH, Ughreja K, Morine KJ, Levine J, Aronovitz MJ, Hill NS, Jaffe IZ, Letarte M, Karas RH.

J Am Heart Assoc. 2014 Jul 11;3(4). pii: e000965. doi: 10.1161/JAHA.114.000965. Erratum in: J Am Heart Assoc. 2014 Aug;3(4):e000419. Ughreja, Kesahn [Corrected to Ughreja, Kishan].

9.

Glycogen synthase kinase-3β inhibition ameliorates cardiac parasympathetic dysfunction in type 1 diabetic Akita mice.

Zhang Y, Welzig CM, Picard KL, Du C, Wang B, Pan JQ, Kyriakis JM, Aronovitz MJ, Claycomb WC, Blanton RM, Park HJ, Galper JB.

Diabetes. 2014 Jun;63(6):2097-113. doi: 10.2337/db12-1459. Epub 2014 Jan 23.

10.

Biventricular remodeling in murine models of right ventricular pressure overload.

Kapur NK, Paruchuri V, Aronovitz MJ, Qiao X, Mackey EE, Daly GH, Ughreja K, Levine J, Blanton R, Hill NS, Karas RH.

PLoS One. 2013 Jul 30;8(7):e70802. doi: 10.1371/journal.pone.0070802. Print 2013.

11.

Rapid estrogen receptor signaling mediates estrogen-induced inhibition of vascular smooth muscle cell proliferation.

Ueda K, Lu Q, Baur W, Aronovitz MJ, Karas RH.

Arterioscler Thromb Vasc Biol. 2013 Aug;33(8):1837-43. doi: 10.1161/ATVBAHA.112.300752. Epub 2013 Jun 6.

12.

Estrogen receptor-mediated regulation of microRNA inhibits proliferation of vascular smooth muscle cells.

Zhao J, Imbrie GA, Baur WE, Iyer LK, Aronovitz MJ, Kershaw TB, Haselmann GM, Lu Q, Karas RH.

Arterioscler Thromb Vasc Biol. 2013 Feb;33(2):257-65. doi: 10.1161/ATVBAHA.112.300200. Epub 2012 Nov 21.

13.

Rapid estrogen receptor signaling is essential for the protective effects of estrogen against vascular injury.

Bernelot Moens SJ, Schnitzler GR, Nickerson M, Guo H, Ueda K, Lu Q, Aronovitz MJ, Nickerson H, Baur WE, Hansen U, Iyer LK, Karas RH.

Circulation. 2012 Oct 16;126(16):1993-2004. doi: 10.1161/CIRCULATIONAHA.112.124529. Epub 2012 Sep 20.

14.

Mineralocorticoid receptor antagonism inhibits vein graft remodeling in mice.

Ehsan A, McGraw AP, Aronovitz MJ, Galayda C, Conte MS, Karas RH, Jaffe IZ.

J Thorac Cardiovasc Surg. 2013 Jun;145(6):1642-9, 1649.e1. doi: 10.1016/j.jtcvs.2012.08.007. Epub 2012 Sep 13.

15.

Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure.

Kapur NK, Wilson S, Yunis AA, Qiao X, Mackey E, Paruchuri V, Baker C, Aronovitz MJ, Karumanchi SA, Letarte M, Kass DA, Mendelsohn ME, Karas RH.

Circulation. 2012 Jun 5;125(22):2728-38. doi: 10.1161/CIRCULATIONAHA.111.080002. Epub 2012 May 16.

16.

Decreased metalloprotease 9 induction, cardiac fibrosis, and higher autophagy after pressure overload in mice lacking the transcriptional regulator p8.

Georgescu SP, Aronovitz MJ, Iovanna JL, Patten RD, Kyriakis JM, Goruppi S.

Am J Physiol Cell Physiol. 2011 Nov;301(5):C1046-56. doi: 10.1152/ajpcell.00211.2011. Epub 2011 Jul 20.

17.

Elevated soluble fms-like tyrosine kinase-1 levels in acute coronary occlusion.

Kapur NK, Heffernan KS, Yunis AA, Nguyen TA, Aronovitz MJ, Parpos P, Wilson S, Baker CK, Esposito ML, Shah A, Kimmelstiel CD, Weintraub A, Karas RH, Mendelsohn ME.

Arterioscler Thromb Vasc Biol. 2011 Feb;31(2):443-50. doi: 10.1161/ATVBAHA.110.215897. Epub 2010 Nov 11.

PMID:
21071694
18.

Deficiency of the transcriptional regulator p8 results in increased autophagy and apoptosis, and causes impaired heart function.

Kong DK, Georgescu SP, Cano C, Aronovitz MJ, Iovanna JL, Patten RD, Kyriakis JM, Goruppi S.

Mol Biol Cell. 2010 Apr 15;21(8):1335-49. doi: 10.1091/mbc.E09-09-0818. Epub 2010 Feb 24.

19.

Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice.

Park HJ, Zhang Y, Du C, Welzig CM, Madias C, Aronovitz MJ, Georgescu SP, Naggar I, Wang B, Kim YB, Blaustein RO, Karas RH, Liao R, Mathews CE, Galper JB.

Circ Res. 2009 Jul 31;105(3):287-94. doi: 10.1161/CIRCRESAHA.109.193995. Epub 2009 May 7.

20.

Estrogen attenuates left ventricular and cardiomyocyte hypertrophy by an estrogen receptor-dependent pathway that increases calcineurin degradation.

Donaldson C, Eder S, Baker C, Aronovitz MJ, Weiss AD, Hall-Porter M, Wang F, Ackerman A, Karas RH, Molkentin JD, Patten RD.

Circ Res. 2009 Jan 30;104(2):265-75, 11p following 275. doi: 10.1161/CIRCRESAHA.108.190397. Epub 2008 Dec 12.

21.

17 Beta-estradiol differentially affects left ventricular and cardiomyocyte hypertrophy following myocardial infarction and pressure overload.

Patten RD, Pourati I, Aronovitz MJ, Alsheikh-Ali A, Eder S, Force T, Mendelsohn ME, Karas RH.

J Card Fail. 2008 Apr;14(3):245-53. doi: 10.1016/j.cardfail.2007.10.024.

22.

Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP.

Park HJ, Georgescu SP, Du C, Madias C, Aronovitz MJ, Welzig CM, Wang B, Begley U, Zhang Y, Blaustein RO, Patten RD, Karas RH, Van Tol HH, Osborne TF, Shimano H, Liao R, Link MS, Galper JB.

J Clin Invest. 2008 Jan;118(1):259-71.

23.

17beta-estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling.

Patten RD, Pourati I, Aronovitz MJ, Baur J, Celestin F, Chen X, Michael A, Haq S, Nuedling S, Grohe C, Force T, Mendelsohn ME, Karas RH.

Circ Res. 2004 Oct 1;95(7):692-9. Epub 2004 Sep 2.

PMID:
15345655
24.

17-beta-estradiol increases cardiac remodeling and mortality in mice with myocardial infarction.

van Eickels M, Patten RD, Aronovitz MJ, Alsheikh-Ali A, Gostyla K, Celestin F, Grohe C, Mendelsohn ME, Karas RH.

J Am Coll Cardiol. 2003 Jun 4;41(11):2084-92. Erratum in: J Am Coll Cardiol. 2003 Jul 2;42(1):following 183.

25.

Effects of angiotensin II receptor blockade versus angiotensin-converting-enzyme inhibition on ventricular remodelling following myocardial infarction in the mouse.

Patten RD, Aronovitz MJ, Einstein M, Lambert M, Pandian NG, Mendelsohn ME, Konstam MA.

Clin Sci (Lond). 2003 Feb;104(2):109-18.

PMID:
12546633
26.

Use of pulse wave and color flow Doppler echocardiography in mouse models of human disease.

Patten RD, Aronovitz MJ, Bridgman P, Pandian NG.

J Am Soc Echocardiogr. 2002 Jul;15(7):708-14.

PMID:
12094169
27.

Effects of estrogen on cardiac electrophysiology in female mice.

Saba S, Zhu W, Aronovitz MJ, Estes NA 3rd, Wang PJ, Mendelsohn ME, Karas RH.

J Cardiovasc Electrophysiol. 2002 Mar;13(3):276-80.

PMID:
11942597
28.

Effects of estrogen on the vascular injury response in estrogen receptor alpha, beta (double) knockout mice.

Karas RH, Schulten H, Pare G, Aronovitz MJ, Ohlsson C, Gustafsson JA, Mendelsohn ME.

Circ Res. 2001 Sep 14;89(6):534-9.

PMID:
11557741
29.

Safety and efficacy of a steerable temperature monitoring microwave catheter system for ventricular myocardial ablation.

VanderBrink BA, Gilbride C, Aronovitz MJ, Lenihan T, Schorn G, Taylor K, Regan JF, Carr K, Schoen FJ, Link MS, Homoud MK, Estes NA 3rd, Wang PJ.

J Cardiovasc Electrophysiol. 2000 Mar;11(3):305-10.

PMID:
10749353
30.

Localization of the sites of conduction abnormalities in a mouse model of myotonic dystrophy.

Saba S, Vanderbrink BA, Luciano B, Aronovitz MJ, Berul CI, Reddy S, Housman D, Mendelsohn ME, Estes NA 3rd, Wang PJ.

J Cardiovasc Electrophysiol. 1999 Sep;10(9):1214-20.

PMID:
10517654
31.

Assessment of atrioventricular nodal physiology in the mouse.

VanderBrink BA, Link MS, Aronovitz MJ, Saba S, Sloan SB, Homoud MK, Estes III NA, Wang PJ.

J Interv Card Electrophysiol. 1999 Oct;3(3):207-12.

PMID:
10490476
32.

DMPK dosage alterations result in atrioventricular conduction abnormalities in a mouse myotonic dystrophy model.

Berul CI, Maguire CT, Aronovitz MJ, Greenwood J, Miller C, Gehrmann J, Housman D, Mendelsohn ME, Reddy S.

J Clin Invest. 1999 Feb;103(4):R1-7.

33.

Familial hypertrophic cardiomyopathy mice display gender differences in electrophysiological abnormalities.

Berul CI, Christe ME, Aronovitz MJ, Maguire CT, Seidman CE, Seidman JG, Mendelsohn ME.

J Interv Card Electrophysiol. 1998 Mar;2(1):7-14.

PMID:
9869991
34.

Ventricular remodeling in a mouse model of myocardial infarction.

Patten RD, Aronovitz MJ, Deras-Mejia L, Pandian NG, Hanak GG, Smith JJ, Mendelsohn ME, Konstam MA.

Am J Physiol. 1998 May;274(5):H1812-20. doi: 10.1152/ajpheart.1998.274.5.H1812.

PMID:
9612394
35.
36.

Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice.

Berul CI, Christe ME, Aronovitz MJ, Seidman CE, Seidman JG, Mendelsohn ME.

J Clin Invest. 1997 Feb 15;99(4):570-6.

37.

In vivo cardiac electrophysiology studies in the mouse.

Berul CI, Aronovitz MJ, Wang PJ, Mendelsohn ME.

Circulation. 1996 Nov 15;94(10):2641-8.

PMID:
8921812
38.

A new platinum balloon-expandable stent (Angiostent) mounted on a high pressure balloon: acute and late results in an atherogenic swine model.

Hijazi ZM, Homoud M, Aronovitz MJ, Smith JJ, Faller GT.

J Invasive Cardiol. 1995 Jun;7(5):127-34.

PMID:
10155095
39.

Antifibrinolytic activity of apolipoprotein(a) in vivo: human apolipoprotein(a) transgenic mice are resistant to tissue plasminogen activator-mediated thrombolysis.

Palabrica TM, Liu AC, Aronovitz MJ, Furie B, Lawn RM, Furie BC.

Nat Med. 1995 Mar;1(3):256-9. Erratum in: Nat Med 1995 Jun;1(6):598.

PMID:
7585043
40.

A new low profile balloon atrial septostomy catheter: initial animal and clinical experience.

Hijazi ZM, Geggel RL, Aronovitz MJ, Marx GR, Rhodes J, Fulton DR.

J Invasive Cardiol. 1994 Jul-Aug;6(6):209-12.

PMID:
10155071
41.

Experimental volume replacement through lower extremity veins.

Stylianos S, Jacir NN, Hoffman MA, Aronovitz MJ, Harris BH.

J Trauma. 1993 Nov;35(5):666-9; discussion 669-70.

PMID:
8230326
42.
43.

Magnetic resonance imaging in ischemic injury after heart transplantation in rats.

Konstam MA, Aronovitz MJ, Runge VM, Isner JM, Foster EA, Kaufman DM, Diehl JT, Dresdale AR, Katzen NA, Kaplan E.

J Heart Lung Transplant. 1991 Sep-Oct;10(5 Pt 1):750-6.

PMID:
1958682
44.

Total lymphoid irradiation and discordant cardiac xenografts.

Kaplan E, Dresdale AR, Diehl JT, Katzen NA, Aronovitz MJ, Konstam MA, Payne DD, Cleveland RJ.

J Heart Transplant. 1990 Jan-Feb;9(1):11-3.

PMID:
2313414
45.

Kinetics of pulmonary platelet deposition and clearance during thrombin-induced microembolism in rabbits.

Konstam MA, Brockway BA, Aronovitz MJ, Ramberg K, Palabrica TM, Otradovec CL, Cooper A, Hill N.

Exp Lung Res. 1989 Dec;15(6):867-79.

PMID:
2612444
46.

Thrombus imaging in a primate model with antibodies specific for an external membrane protein of activated platelets.

Palabrica TM, Furie BC, Konstam MA, Aronovitz MJ, Connolly R, Brockway BA, Ramberg KL, Furie B.

Proc Natl Acad Sci U S A. 1989 Feb;86(3):1036-40.

47.

Magnetic resonance imaging with gadolinium-DTPA for detecting cardiac transplant rejection in rats.

Konstam MA, Aronovitz MJ, Runge VM, Kaufman DM, Brockway BA, Isner JM, Katzen NA, Dresdale AR, Diehl JT, Kaplan E, et al.

Circulation. 1988 Nov;78(5 Pt 2):III87-94.

PMID:
3052922
48.

Donor-specific transfusion and cardiac xenografts.

Kaplan E, Dresdale AR, Diehl JT, Aronovitz MJ, Konstam MA, Katzen NA, Gould KE, Isner JM, Connolly RJ, Payne DD, et al.

Transplantation. 1988 Oct;46(4):605-7. No abstract available.

PMID:
3051573
49.

Effects of indomethacin in utero on the pulmonary vasculature of the newborn guinea pig.

Demello DE, Murphy JD, Aronovitz MJ, Davies P, Reid LM.

Pediatr Res. 1987 Dec;22(6):693-7.

PMID:
3431953
50.

Pulmonary artery structural changes in two colonies of rats with different sensitivity to chronic hypoxia.

Langleben D, Jones RC, Aronovitz MJ, Hill NS, Ou LC, Reid LM.

Am J Pathol. 1987 Jul;128(1):61-6.

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